{"id":"https://openalex.org/W7147241971","doi":"https://doi.org/10.70675/8fc153dfzc95cz4209zabf7z1567442c940d","title":"La microalgue Odontella aurita pr\u00e9vient l'insulino-r\u00e9sistance et l'inflammation h\u00e9patiques induites par un r\u00e9gime hyper-lipidique : mise en \u00e9vidence des m\u00e9canismes insulino-sensibilisateurs des acides gras polyinsatur\u00e9s omega-3 au niveau neuronal.","display_name":"La microalgue Odontella aurita pr\u00e9vient l'insulino-r\u00e9sistance et l'inflammation h\u00e9patiques induites par un r\u00e9gime hyper-lipidique : mise en \u00e9vidence des m\u00e9canismes insulino-sensibilisateurs des acides gras polyinsatur\u00e9s omega-3 au niveau neuronal.","publication_year":2016,"publication_date":"2016-03-03","ids":{"openalex":"https://openalex.org/W7147241971","doi":"https://doi.org/10.70675/8fc153dfzc95cz4209zabf7z1567442c940d","mag":"2311197248"},"language":"fr","primary_location":{"id":"doi:10.70675/8fc153dfzc95cz4209zabf7z1567442c940d","doi":"https://doi.org/10.70675/8fc153dfzc95cz4209zabf7z1567442c940d","is_oa":false,"landing_page_url":"https://doi.org/10.70675/8fc153dfzc95cz4209zabf7z1567442c940d","pdf_url":null,"source":{"id":"https://openalex.org/S4406923047","display_name":"theses.fr (ABES)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Universit\u00e9 Paris-Saclay (ComUE)","raw_type":"dissertation"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://www.theses.fr/2016SACLS050/document","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5022185124","display_name":"Hamza Amine","orcid":"https://orcid.org/0000-0001-9811-1283","observed_orcids":["https://orcid.org/0000-0001-9811-1283"]},"institutions":[{"id":"https://openalex.org/I277688954","display_name":"Universit\u00e9 Paris-Saclay","ror":"https://ror.org/03xjwb503","country_code":"FR","type":"education","lineage":["https://openalex.org/I277688954"]}],"countries":["FR"],"is_corresponding":true,"raw_author_name":"Hamza Amine","raw_affiliation_strings":["Universit\u00e9 Paris-Saclay (ComUE)"],"raw_orcid":"https://orcid.org/0000-0001-9811-1283","affiliations":[{"raw_affiliation_string":"Universit\u00e9 Paris-Saclay (ComUE)","institution_ids":["https://openalex.org/I277688954"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5022185124"],"corresponding_institution_ids":["https://openalex.org/I277688954"],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10387","display_name":"Fatty Acid Research and Health","score":0.9491999745368958,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10387","display_name":"Fatty Acid Research and Health","score":0.9491999745368958,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11390","display_name":"Seaweed-derived Bioactive Compounds","score":0.0203000009059906,"subfield":{"id":"https://openalex.org/subfields/1104","display_name":"Aquatic Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11140","display_name":"Natural Antidiabetic Agents Studies","score":0.010599999688565731,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/omega-3-polyunsaturated-fatty-acids","display_name":"omega-3 polyunsaturated fatty acids","score":0.8309999704360962},{"id":"https://openalex.org/keywords/eicosapentaenoic-acid","display_name":"eicosapentaenoic acid","score":0.984000027179718},{"id":"https://openalex.org/keywords/insulin-resistance","display_name":"insulin resistance","score":0.9139999747276306},{"id":"https://openalex.org/keywords/type-2-diabetes","display_name":"type 2 diabetes","score":0.7630000114440918},{"id":"https://openalex.org/keywords/high-fat-diet","display_name":"high-fat diet","score":0.7310000061988831},{"id":"https://openalex.org/keywords/liver-inflammation","display_name":"liver inflammation","score":0.7870000004768372},{"id":"https://openalex.org/keywords/metabolic-syndrome","display_name":"metabolic syndrome","score":0.7450000047683716},{"id":"https://openalex.org/keywords/tlr4","display_name":"TLR4","score":0.7009999752044678},{"id":"https://openalex.org/keywords/jnk","display_name":"JNK","score":0.5080000162124634},{"id":"https://openalex.org/keywords/p38-mapk","display_name":"p38 MAPK","score":0.9110000133514404},{"id":"https://openalex.org/keywords/insulin-receptor-tyrosine-kinase","display_name":"insulin receptor tyrosine kinase","score":0.8379999995231628},{"id":"https://openalex.org/keywords/neuroinflammation","display_name":"neuroinflammation","score":0.4950000047683716},{"id":"https://openalex.org/keywords/oxidative-stress","display_name":"oxidative stress","score":0.5569999814033508},{"id":"https://openalex.org/keywords/lipid-peroxidation","display_name":"lipid peroxidation","score":0.4359999895095825}],"concepts":[{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.45489999651908875},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.328900009393692},{"id":"https://openalex.org/C15708023","wikidata":"https://www.wikidata.org/wiki/Q80083","display_name":"Humanities","level":1,"score":0.225600004196167},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.22130000591278076},{"id":"https://openalex.org/C142362112","wikidata":"https://www.wikidata.org/wiki/Q735","display_name":"Art","level":0,"score":0.19429999589920044},{"id":"https://openalex.org/C29456083","wikidata":"https://www.wikidata.org/wiki/Q1221899","display_name":"Gynecology","level":1,"score":0.18889999389648438},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.17440000176429749},{"id":"https://openalex.org/C2986587452","wikidata":"https://www.wikidata.org/wiki/Q938438","display_name":"Statistical analysis","level":2,"score":0.1599999964237213},{"id":"https://openalex.org/C52909226","wikidata":"https://www.wikidata.org/wiki/Q5462835","display_name":"Fluorescent labelling","level":3,"score":0.15479999780654907},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.15459999442100525}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.70675/8fc153dfzc95cz4209zabf7z1567442c940d","doi":"https://doi.org/10.70675/8fc153dfzc95cz4209zabf7z1567442c940d","is_oa":false,"landing_page_url":"https://doi.org/10.70675/8fc153dfzc95cz4209zabf7z1567442c940d","pdf_url":null,"source":{"id":"https://openalex.org/S4406923047","display_name":"theses.fr (ABES)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Universit\u00e9 Paris-Saclay (ComUE)","raw_type":"dissertation"},{"id":"pmh:2016SACLS050","doi":null,"is_oa":true,"landing_page_url":"http://www.theses.fr/2016SACLS050/document","pdf_url":null,"source":{"id":"https://openalex.org/S4406923047","display_name":"theses.fr (ABES)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Electronic Thesis or Dissertation"},{"id":"pmh:oai:HAL:tel-01722423v1","doi":null,"is_oa":true,"landing_page_url":"https://theses.hal.science/tel-01722423","pdf_url":null,"source":{"id":"https://openalex.org/S4306402512","display_name":"HAL","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4405252976","host_organization_name":"Centre pour la Communication Scientifique Directe","host_organization_lineage":["https://openalex.org/I4405252976"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Biologie cellulaire. Universit\u00e9 Paris Saclay (COmUE); Universit\u00e9 Hassan II (Casablanca, Maroc). Facult\u00e9 des Sciences, 2016. Fran\u00e7ais. ⟨NNT : 2016SACLS050⟩","raw_type":"info:eu-repo/semantics/doctoralThesis"},{"id":"mag:2311197248","doi":null,"is_oa":false,"landing_page_url":"https://hal.archives-ouvertes.fr/tel-01722423v1","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:2016SACLS050","doi":null,"is_oa":true,"landing_page_url":"http://www.theses.fr/2016SACLS050/document","pdf_url":null,"source":{"id":"https://openalex.org/S4406923047","display_name":"theses.fr (ABES)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Electronic Thesis or Dissertation"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9537000060081482}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":727,"referenced_works":["https://openalex.org/W9809145","https://openalex.org/W31735925","https://openalex.org/W42380194","https://openalex.org/W184717169","https://openalex.org/W230940498","https://openalex.org/W748217515","https://openalex.org/W874202208","https://openalex.org/W1045140098","https://openalex.org/W1481314844","https://openalex.org/W1483162601","https://openalex.org/W1496640920","https://openalex.org/W1499978168","https://openalex.org/W1501449620","https://openalex.org/W1502274943","https://openalex.org/W1507716785","https://openalex.org/W1508602313","https://openalex.org/W1508994506","https://openalex.org/W1512966860","https://openalex.org/W1513089486","https://openalex.org/W1517759896","https://openalex.org/W1517818296","https://openalex.org/W1518698643","https://openalex.org/W1519843522","https://openalex.org/W1524030768","https://openalex.org/W1524321743","https://openalex.org/W1529636865","https://openalex.org/W1530052324","https://openalex.org/W1530179357","https://openalex.org/W1530406019","https://openalex.org/W1531763753","https://openalex.org/W1534057962","https://openalex.org/W1534360145","https://openalex.org/W1534710388","https://openalex.org/W1551216731","https://openalex.org/W1557744782","https://openalex.org/W1559597555","https://openalex.org/W1561443084","https://openalex.org/W1562891630","https://openalex.org/W1564546569","https://openalex.org/W1572696798","https://openalex.org/W1581857504","https://openalex.org/W1583767403","https://openalex.org/W1587875569","https://openalex.org/W1593760300","https://openalex.org/W1594930126","https://openalex.org/W1596881606","https://openalex.org/W1608606552","https://openalex.org/W1624505911","https://openalex.org/W1674259800","https://openalex.org/W1675830194","https://openalex.org/W1697523131","https://openalex.org/W1698695320","https://openalex.org/W1708748675","https://openalex.org/W1756039870","https://openalex.org/W1764140709","https://openalex.org/W1772991109","https://openalex.org/W1797267066","https://openalex.org/W1802404595","https://openalex.org/W1841050729","https://openalex.org/W1871669466","https://openalex.org/W1886303132","https://openalex.org/W1898464912","https://openalex.org/W1911968642","https://openalex.org/W1919647167","https://openalex.org/W1944741194","https://openalex.org/W1953016419","https://openalex.org/W1959312622","https://openalex.org/W1963751749","https://openalex.org/W1964044812","https://openalex.org/W1964465655","https://openalex.org/W1965971815","https://openalex.org/W1966181749","https://openalex.org/W1966568934","https://openalex.org/W1966608496","https://openalex.org/W1966772446","https://openalex.org/W1967161323","https://openalex.org/W1967357406","https://openalex.org/W1967661330","https://openalex.org/W1968336033","https://openalex.org/W1968476943","https://openalex.org/W1969175670","https://openalex.org/W1969403095","https://openalex.org/W1969501356","https://openalex.org/W1969752278","https://openalex.org/W1969973773","https://openalex.org/W1970187819","https://openalex.org/W1970336470","https://openalex.org/W1970748867","https://openalex.org/W1971200894","https://openalex.org/W1971452427","https://openalex.org/W1971475788","https://openalex.org/W1971710102","https://openalex.org/W1972590376","https://openalex.org/W1972934337","https://openalex.org/W1973372369","https://openalex.org/W1974033843","https://openalex.org/W1974055405","https://openalex.org/W1974075629","https://openalex.org/W1974092523","https://openalex.org/W1974186154","https://openalex.org/W1974241409","https://openalex.org/W1974773133","https://openalex.org/W1974802955","https://openalex.org/W1974872833","https://openalex.org/W1975537939","https://openalex.org/W1975945337","https://openalex.org/W1976029372","https://openalex.org/W1977001646","https://openalex.org/W1977128714","https://openalex.org/W1977797609","https://openalex.org/W1978220485","https://openalex.org/W1978281808","https://openalex.org/W1979094012","https://openalex.org/W1979101494","https://openalex.org/W1979598489","https://openalex.org/W1980152778","https://openalex.org/W1980376777","https://openalex.org/W1981411312","https://openalex.org/W1981642488","https://openalex.org/W1981796916","https://openalex.org/W1982920909","https://openalex.org/W1983856784","https://openalex.org/W1984159784","https://openalex.org/W1984456316","https://openalex.org/W1985113364","https://openalex.org/W1985473826","https://openalex.org/W1985538633","https://openalex.org/W1986602268","https://openalex.org/W1986781079","https://openalex.org/W1987125079","https://openalex.org/W1987453246","https://openalex.org/W1987597166","https://openalex.org/W1988870963","https://openalex.org/W1989020172","https://openalex.org/W1989321724","https://openalex.org/W1989324173","https://openalex.org/W1989656760","https://openalex.org/W1990433634","https://openalex.org/W1990465836","https://openalex.org/W1990657409","https://openalex.org/W1991079474","https://openalex.org/W1991246265","https://openalex.org/W1991401793","https://openalex.org/W1991619890","https://openalex.org/W1991710558","https://openalex.org/W1992245975","https://openalex.org/W1992489770","https://openalex.org/W1993211211","https://openalex.org/W1993418845","https://openalex.org/W1993429838","https://openalex.org/W1993431258","https://openalex.org/W1993762569","https://openalex.org/W1993867495","https://openalex.org/W1993884627","https://openalex.org/W1995020420","https://openalex.org/W1995356743","https://openalex.org/W1995687483","https://openalex.org/W1995866508","https://openalex.org/W1995927479","https://openalex.org/W1996089807","https://openalex.org/W1996120614","https://openalex.org/W1996257405","https://openalex.org/W1996293435","https://openalex.org/W1996560248","https://openalex.org/W1996669341","https://openalex.org/W1996713062","https://openalex.org/W1997978122","https://openalex.org/W1998024601","https://openalex.org/W1998365634","https://openalex.org/W1998525855","https://openalex.org/W1998585620","https://openalex.org/W1998836938","https://openalex.org/W1999249055","https://openalex.org/W1999260487","https://openalex.org/W1999634145","https://openalex.org/W1999654071","https://openalex.org/W1999824494","https://openalex.org/W1999971397","https://openalex.org/W2000054651","https://openalex.org/W2000084601","https://openalex.org/W2000665430","https://openalex.org/W2001123017","https://openalex.org/W2001197365","https://openalex.org/W2001727439","https://openalex.org/W2002070144","https://openalex.org/W2002127663","https://openalex.org/W2002938711","https://openalex.org/W2003385732","https://openalex.org/W2003659422","https://openalex.org/W2004728333","https://openalex.org/W2005166222","https://openalex.org/W2005527509","https://openalex.org/W2005745228","https://openalex.org/W2005827500","https://openalex.org/W2005955483","https://openalex.org/W2006702634","https://openalex.org/W2006706785","https://openalex.org/W2007194743","https://openalex.org/W2007751980","https://openalex.org/W2008311512","https://openalex.org/W2008810276","https://openalex.org/W2008821667","https://openalex.org/W2009354994","https://openalex.org/W2009458118","https://openalex.org/W2010447832","https://openalex.org/W2010590191","https://openalex.org/W2010703494","https://openalex.org/W2010763118","https://openalex.org/W2010911569","https://openalex.org/W2010955929","https://openalex.org/W2011210301","https://openalex.org/W2011211995","https://openalex.org/W2011282245","https://openalex.org/W2011723360","https://openalex.org/W2012433024","https://openalex.org/W2013205499","https://openalex.org/W2014702667","https://openalex.org/W2014887370","https://openalex.org/W2015263036","https://openalex.org/W2015925329","https://openalex.org/W2016248729","https://openalex.org/W2016790352","https://openalex.org/W2017296879","https://openalex.org/W2017712441","https://openalex.org/W2018946767","https://openalex.org/W2019009753","https://openalex.org/W2020275122","https://openalex.org/W2020650452","https://openalex.org/W2020902595","https://openalex.org/W2021523302","https://openalex.org/W2021861695","https://openalex.org/W2021988516","https://openalex.org/W2022094791","https://openalex.org/W2022129879","https://openalex.org/W2022294953","https://openalex.org/W2022464927","https://openalex.org/W2022925818","https://openalex.org/W2022930571","https://openalex.org/W2023751903","https://openalex.org/W2024573537","https://openalex.org/W2024813257","https://openalex.org/W2024886564","https://openalex.org/W2025578932","https://openalex.org/W2025607561","https://openalex.org/W2026927520","https://openalex.org/W2027855860","https://openalex.org/W2027950474","https://openalex.org/W2028232702","https://openalex.org/W2028320377","https://openalex.org/W2028395411","https://openalex.org/W2028790719","https://openalex.org/W2029667930","https://openalex.org/W2029716970","https://openalex.org/W2030029464","https://openalex.org/W2030535042","https://openalex.org/W2030778616","https://openalex.org/W2030899725","https://openalex.org/W2030977583","https://openalex.org/W2031463153","https://openalex.org/W2031504013","https://openalex.org/W2031823238","https://openalex.org/W2032125791","https://openalex.org/W2032140907","https://openalex.org/W2032984787","https://openalex.org/W2033330574","https://openalex.org/W2033524876","https://openalex.org/W2033728841","https://openalex.org/W2035357682","https://openalex.org/W2036044659","https://openalex.org/W2037021965","https://openalex.org/W2037081680","https://openalex.org/W2038556759","https://openalex.org/W2038842701","https://openalex.org/W2038884731","https://openalex.org/W2038941282","https://openalex.org/W2038961236","https://openalex.org/W2039054036","https://openalex.org/W2039193709","https://openalex.org/W2040328785","https://openalex.org/W2040692229","https://openalex.org/W2040732264","https://openalex.org/W2040834782","https://openalex.org/W2040901874","https://openalex.org/W2041216506","https://openalex.org/W2041608072","https://openalex.org/W2042686252","https://openalex.org/W2042706232","https://openalex.org/W2043823247","https://openalex.org/W2044880963","https://openalex.org/W2046277604","https://openalex.org/W2046402204","https://openalex.org/W2046422846","https://openalex.org/W2046535955","https://openalex.org/W2047034783","https://openalex.org/W2047543296","https://openalex.org/W2048236176","https://openalex.org/W2048363513","https://openalex.org/W2048819152","https://openalex.org/W2049342816","https://openalex.org/W2049677309","https://openalex.org/W2049875806","https://openalex.org/W2049881486","https://openalex.org/W2049965571","https://openalex.org/W2050035145","https://openalex.org/W2050259739","https://openalex.org/W2050323812","https://openalex.org/W2050967471","https://openalex.org/W2051192888","https://openalex.org/W2051303794","https://openalex.org/W2051304353","https://openalex.org/W2051628416","https://openalex.org/W2051758765","https://openalex.org/W2051940924","https://openalex.org/W2051993213","https://openalex.org/W2052446906","https://openalex.org/W2052506761","https://openalex.org/W2053127486","https://openalex.org/W2053154947","https://openalex.org/W2053298147","https://openalex.org/W2053761680","https://openalex.org/W2054016219","https://openalex.org/W2054027245","https://openalex.org/W2054101408","https://openalex.org/W2054257916","https://openalex.org/W2055046559","https://openalex.org/W2055269050","https://openalex.org/W2055598943","https://openalex.org/W2056181578","https://openalex.org/W2056367020","https://openalex.org/W2057114766","https://openalex.org/W2057126981","https://openalex.org/W2057193041","https://openalex.org/W2058083313","https://openalex.org/W2058138221","https://openalex.org/W2058586676","https://openalex.org/W2059039575","https://openalex.org/W2059511498","https://openalex.org/W2059713297","https://openalex.org/W2059842910","https://openalex.org/W2060016290","https://openalex.org/W2060129133","https://openalex.org/W2060239530","https://openalex.org/W2060294481","https://openalex.org/W2060622317","https://openalex.org/W2060682066","https://openalex.org/W2060817939","https://openalex.org/W2060915586","https://openalex.org/W2061261165","https://openalex.org/W2061613314","https://openalex.org/W2062322478","https://openalex.org/W2062390485","https://openalex.org/W2062835892","https://openalex.org/W2063131576","https://openalex.org/W2063535738","https://openalex.org/W2064091786","https://openalex.org/W2064119981","https://openalex.org/W2064125892","https://openalex.org/W2064399682","https://openalex.org/W2064434693","https://openalex.org/W2064435741","https://openalex.org/W2064504332","https://openalex.org/W2064801081","https://openalex.org/W2065028165","https://openalex.org/W2065322400","https://openalex.org/W2065402200","https://openalex.org/W2065501573","https://openalex.org/W2065697164","https://openalex.org/W2065789432","https://openalex.org/W2065912402","https://openalex.org/W2066160102","https://openalex.org/W2066171146","https://openalex.org/W2066696278","https://openalex.org/W2066721136","https://openalex.org/W2067096633","https://openalex.org/W2067118306","https://openalex.org/W2067226772","https://openalex.org/W2067503419","https://openalex.org/W2067875627","https://openalex.org/W2068583404","https://openalex.org/W2068908759","https://openalex.org/W2069711307","https://openalex.org/W2069746141","https://openalex.org/W2070119291","https://openalex.org/W2070164366","https://openalex.org/W2070197168","https://openalex.org/W2070358670","https://openalex.org/W2071470362","https://openalex.org/W2072367079","https://openalex.org/W2072676249","https://openalex.org/W2073565085","https://openalex.org/W2073603433","https://openalex.org/W2073751076","https://openalex.org/W2073878918","https://openalex.org/W2073959976","https://openalex.org/W2074125728","https://openalex.org/W2074351291","https://openalex.org/W2075171810","https://openalex.org/W2075275904","https://openalex.org/W2075521286","https://openalex.org/W2075875125","https://openalex.org/W2076310317","https://openalex.org/W2076865656","https://openalex.org/W2078316187","https://openalex.org/W2079229709","https://openalex.org/W2079395662","https://openalex.org/W2079480602","https://openalex.org/W2079520104","https://openalex.org/W2079659159","https://openalex.org/W2079834984","https://openalex.org/W2080217697","https://openalex.org/W2080415718","https://openalex.org/W2080549540","https://openalex.org/W2080594285","https://openalex.org/W2080784038","https://openalex.org/W2080932392","https://openalex.org/W2081100041","https://openalex.org/W2081393100","https://openalex.org/W2081728052","https://openalex.org/W2082432928","https://openalex.org/W2082817623","https://openalex.org/W2082835899","https://openalex.org/W2083050494","https://openalex.org/W2083374924","https://openalex.org/W2083380961","https://openalex.org/W2083406653","https://openalex.org/W2083457336","https://openalex.org/W2083612635","https://openalex.org/W2083636435","https://openalex.org/W2083661583","https://openalex.org/W2083666530","https://openalex.org/W2083682196","https://openalex.org/W2084521532","https://openalex.org/W2084618648","https://openalex.org/W2085181449","https://openalex.org/W2085379045","https://openalex.org/W2086102771","https://openalex.org/W2086388293","https://openalex.org/W2086410640","https://openalex.org/W2086752996","https://openalex.org/W2087127797","https://openalex.org/W2087296641","https://openalex.org/W2087622626","https://openalex.org/W2087752240","https://openalex.org/W2087785956","https://openalex.org/W2088012387","https://openalex.org/W2088085350","https://openalex.org/W2088183665","https://openalex.org/W2088666203","https://openalex.org/W2088892125","https://openalex.org/W2088940658","https://openalex.org/W2089269477","https://openalex.org/W2089284695","https://openalex.org/W2089567564","https://openalex.org/W2089889881","https://openalex.org/W2090549717","https://openalex.org/W2090640877","https://openalex.org/W2091725117","https://openalex.org/W2091759162","https://openalex.org/W2092004124","https://openalex.org/W2092817365","https://openalex.org/W2093894290","https://openalex.org/W2094016960","https://openalex.org/W2094498915","https://openalex.org/W2094644629","https://openalex.org/W2094884053","https://openalex.org/W2095126334","https://openalex.org/W2095252238","https://openalex.org/W2095799421","https://openalex.org/W2096032494","https://openalex.org/W2096429786","https://openalex.org/W2096773810","https://openalex.org/W2097278274","https://openalex.org/W2097447032","https://openalex.org/W2097763382","https://openalex.org/W2098628437","https://openalex.org/W2098768454","https://openalex.org/W2098901296","https://openalex.org/W2099025205","https://openalex.org/W2099587538","https://openalex.org/W2100232436","https://openalex.org/W2100599316","https://openalex.org/W2100897987","https://openalex.org/W2101076088","https://openalex.org/W2101328621","https://openalex.org/W2101510325","https://openalex.org/W2101921785","https://openalex.org/W2102683312","https://openalex.org/W2103010344","https://openalex.org/W2103402907","https://openalex.org/W2103488083","https://openalex.org/W2103832212","https://openalex.org/W2105912552","https://openalex.org/W2106173125","https://openalex.org/W2107000838","https://openalex.org/W2107572553","https://openalex.org/W2107674876","https://openalex.org/W2107863336","https://openalex.org/W2108266286","https://openalex.org/W2108373994","https://openalex.org/W2108544809","https://openalex.org/W2109889741","https://openalex.org/W2110331338","https://openalex.org/W2110500106","https://openalex.org/W2110678596","https://openalex.org/W2110846639","https://openalex.org/W2110871895","https://openalex.org/W2111192178","https://openalex.org/W2111428445","https://openalex.org/W2111622333","https://openalex.org/W2112662561","https://openalex.org/W2113039508","https://openalex.org/W2114597116","https://openalex.org/W2114650931","https://openalex.org/W2115138453","https://openalex.org/W2115449075","https://openalex.org/W2115681043","https://openalex.org/W2115767669","https://openalex.org/W2117209669","https://openalex.org/W2117290383","https://openalex.org/W2117365118","https://openalex.org/W2117634500","https://openalex.org/W2117752401","https://openalex.org/W2118055379","https://openalex.org/W2118338384","https://openalex.org/W2118499682","https://openalex.org/W2118688616","https://openalex.org/W2118923573","https://openalex.org/W2118969396","https://openalex.org/W2118991004","https://openalex.org/W2121042850","https://openalex.org/W2121309304","https://openalex.org/W2121790250","https://openalex.org/W2122248435","https://openalex.org/W2122393978","https://openalex.org/W2122567567","https://openalex.org/W2122660225","https://openalex.org/W2122814014","https://openalex.org/W2123229219","https://openalex.org/W2123479382","https://openalex.org/W2123521914","https://openalex.org/W2123577868","https://openalex.org/W2123704636","https://openalex.org/W2124032393","https://openalex.org/W2124035752","https://openalex.org/W2124311814","https://openalex.org/W2124343538","https://openalex.org/W2124568143","https://openalex.org/W2124588973","https://openalex.org/W2124688365","https://openalex.org/W2124733230","https://openalex.org/W2124848390","https://openalex.org/W2125058279","https://openalex.org/W2125510262","https://openalex.org/W2126393987","https://openalex.org/W2126584538","https://openalex.org/W2126875959","https://openalex.org/W2126889659","https://openalex.org/W2127187614","https://openalex.org/W2127304365","https://openalex.org/W2127337885","https://openalex.org/W2127616500","https://openalex.org/W2127856503","https://openalex.org/W2128337755","https://openalex.org/W2128344890","https://openalex.org/W2128485668","https://openalex.org/W2128842224","https://openalex.org/W2129088717","https://openalex.org/W2129125398","https://openalex.org/W2129316761","https://openalex.org/W2129319296","https://openalex.org/W2129578178","https://openalex.org/W2129706448","https://openalex.org/W2129709499","https://openalex.org/W2130421043","https://openalex.org/W2130489314","https://openalex.org/W2130495917","https://openalex.org/W2130766522","https://openalex.org/W2131094572","https://openalex.org/W2131536322","https://openalex.org/W2131754310","https://openalex.org/W2131836263","https://openalex.org/W2132258820","https://openalex.org/W2132554143","https://openalex.org/W2132806782","https://openalex.org/W2133010654","https://openalex.org/W2133795831","https://openalex.org/W2134100055","https://openalex.org/W2134414477","https://openalex.org/W2134944069","https://openalex.org/W2135238555","https://openalex.org/W2135608471","https://openalex.org/W2135766812","https://openalex.org/W2135896596","https://openalex.org/W2136024338","https://openalex.org/W2136274729","https://openalex.org/W2136400536","https://openalex.org/W2137274603","https://openalex.org/W2138193344","https://openalex.org/W2138271889","https://openalex.org/W2138504016","https://openalex.org/W2138590740","https://openalex.org/W2139019841","https://openalex.org/W2139191784","https://openalex.org/W2140653555","https://openalex.org/W2140793658","https://openalex.org/W2142436967","https://openalex.org/W2142458796","https://openalex.org/W2142596209","https://openalex.org/W2142932338","https://openalex.org/W2143104968","https://openalex.org/W2143112776","https://openalex.org/W2143539807","https://openalex.org/W2143809126","https://openalex.org/W2144146259","https://openalex.org/W2144411635","https://openalex.org/W2144498167","https://openalex.org/W2144632432","https://openalex.org/W2144736021","https://openalex.org/W2145142659","https://openalex.org/W2145330768","https://openalex.org/W2145437385","https://openalex.org/W2145506695","https://openalex.org/W2146052109","https://openalex.org/W2146175913","https://openalex.org/W2146187080","https://openalex.org/W2147029239","https://openalex.org/W2147658040","https://openalex.org/W2147825853","https://openalex.org/W2148345765","https://openalex.org/W2148387062","https://openalex.org/W2148722507","https://openalex.org/W2149034507","https://openalex.org/W2149613768","https://openalex.org/W2151064573","https://openalex.org/W2151175711","https://openalex.org/W2151335106","https://openalex.org/W2151465653","https://openalex.org/W2151604950","https://openalex.org/W2151938344","https://openalex.org/W2152409266","https://openalex.org/W2152429535","https://openalex.org/W2152513016","https://openalex.org/W2152591650","https://openalex.org/W2152817152","https://openalex.org/W2153722087","https://openalex.org/W2154524115","https://openalex.org/W2154621132","https://openalex.org/W2154713680","https://openalex.org/W2154993634","https://openalex.org/W2155010729","https://openalex.org/W2156260257","https://openalex.org/W2156280702","https://openalex.org/W2156414024","https://openalex.org/W2157296874","https://openalex.org/W2157510059","https://openalex.org/W2157559566","https://openalex.org/W2158061384","https://openalex.org/W2158360711","https://openalex.org/W2158594746","https://openalex.org/W2159685920","https://openalex.org/W2159951890","https://openalex.org/W2159988116","https://openalex.org/W2160234571","https://openalex.org/W2161012482","https://openalex.org/W2161226168","https://openalex.org/W2161324995","https://openalex.org/W2161651062","https://openalex.org/W2161914374","https://openalex.org/W2161972691","https://openalex.org/W2162188338","https://openalex.org/W2162563981","https://openalex.org/W2162614886","https://openalex.org/W2162778157","https://openalex.org/W2162792640","https://openalex.org/W2163051017","https://openalex.org/W2163591544","https://openalex.org/W2163805272","https://openalex.org/W2163837156","https://openalex.org/W2164346577","https://openalex.org/W2164471793","https://openalex.org/W2164865997","https://openalex.org/W2165189049","https://openalex.org/W2165708021","https://openalex.org/W2165857119","https://openalex.org/W2166165585","https://openalex.org/W2166544755","https://openalex.org/W2167213027","https://openalex.org/W2167234504","https://openalex.org/W2167793054","https://openalex.org/W2167874330","https://openalex.org/W2168135465","https://openalex.org/W2169654877","https://openalex.org/W2170708534","https://openalex.org/W2170844731","https://openalex.org/W2170869159","https://openalex.org/W2171142773","https://openalex.org/W2171719931","https://openalex.org/W2172053085","https://openalex.org/W2177335585","https://openalex.org/W2180827867","https://openalex.org/W2189933127","https://openalex.org/W2192932552","https://openalex.org/W2194294353","https://openalex.org/W2199513918","https://openalex.org/W2219809581","https://openalex.org/W2241735732","https://openalex.org/W2276615036","https://openalex.org/W2304671461","https://openalex.org/W2309312299","https://openalex.org/W2318071784","https://openalex.org/W2318799649","https://openalex.org/W2318811682","https://openalex.org/W2319361543","https://openalex.org/W2325223362","https://openalex.org/W2332137635","https://openalex.org/W2333084676","https://openalex.org/W2334337188","https://openalex.org/W2400149408","https://openalex.org/W2411826498","https://openalex.org/W2426939044","https://openalex.org/W2528661075","https://openalex.org/W4237075664","https://openalex.org/W4238567307","https://openalex.org/W4242539867","https://openalex.org/W4252765144","https://openalex.org/W4256252393","https://openalex.org/W7098669547"],"related_works":["https://openalex.org/W4392487806","https://openalex.org/W2180827867","https://openalex.org/W7147568083","https://openalex.org/W1963530660","https://openalex.org/W4392218286","https://openalex.org/W2023251601","https://openalex.org/W7148974308","https://openalex.org/W2133732735","https://openalex.org/W2901141535","https://openalex.org/W2092907349"],"abstract_inverted_index":{"Le":[0,188],"syndrome":[1,62,595],"m\u00e9tabolique":[2,63],"est":[3,29,232,264,420,531],"caract\u00e9ris\u00e9":[4],"par":[5,64,117,151,212,219,345,570],"un":[6,38,118,203,309],"ensemble":[7],"de":[8,24,27,36,40,46,59,66,80,87,109,154,160,165,175,196,207,214,228,230,283,314,328,330,340,369,404,415,430,468,490,501,524,534,542,549,578,581,583,590],"perturbations":[9],"m\u00e9tabolique.":[10,596],"Il":[11],"inclut":[12],"la":[13,17,47,73,107,112,176,208,220,248,271,277,296,315,326,341,352,396,405,418,426,449,463,477,483,525,529,550,565,576,579],"dyslipid\u00e9mie,":[14],"l\u2019ob\u00e9sit\u00e9":[15,110],"abdominale,":[16],"r\u00e9sistance":[18,74,113,145,209,297,316,342,566],"\u00e0":[19,31,75,114,143,146,180,193,210,258,280,299,317,343,382,448,567],"l\u2019insuline":[20,76,115,147],"et":[21,55,77,104,111,222,240,252,303,332,409,424,429,445,462,465,471,485,536,545,564,593],"l\u2019hypertension.":[22],"L\u2019association":[23],"ces":[25,553],"facteurs":[26,58],"risques":[28,60],"li\u00e9e":[30],"une":[32,97,144,152,158,173,194,281],"augmentation":[33,153,195],"du":[34,61,163,178,198,244,256,273,285,588,594],"risque":[35],"d\u00e9velopper":[37],"diab\u00e8te":[39,79,589],"type-2.":[41],"Les":[42],"acides":[43,122,347,558,572],"gras":[44,123,348,387,559,573],"polyinsatur\u00e9s":[45,560],"famille":[48],"des":[49,216,236,291,305,356,359,441],"om\u00e9ga-3":[50,561],"ont":[51,377],"plusieurs":[52],"effets":[53,523,548],"biologiques":[54],"modulent":[56],"les":[57,253,321,334,346,365,374,413,522,547,557,571],"l\u2019interm\u00e9diaire":[65],"multiples":[67],"m\u00e9canismes.":[68],"Cependant,":[69,242],"leurs":[70],"impacts":[71],"sur":[72,106,412,488],"le":[78,133,169,223,407,410,434,437,454,486,494,497,505,517,532,537],"type":[81,591],"2":[82,592],"sont":[83],"encore":[84],"inconnus.Au":[85],"cours":[86],"ce":[88],"travail,":[89],"nous":[90,129,362,400],"avons":[91,130,363,401,474,513],"\u00e9tudi\u00e9":[92,476],"l\u2019effet":[93,459],"d\u2019Odontella":[94],"aurita":[95],"(OA),":[96],"microalgue":[98,249,278],"riche":[99,120],"en":[100,121,182,354,539],"EPA":[101],"(AGPI":[102],"om\u00e9ga-3)":[103],"antioxydants,":[105],"pr\u00e9vention":[108],"induites":[116],"r\u00e9gime":[119,134,170,189,245,274],"satur\u00e9s":[124,574],"High-Fat":[125],"(HF).":[126],"En":[127,225,372,492,527],"effet,":[128,226,373,493],"montr\u00e9":[131,514],"que":[132,351,504,516,556],"HF":[135,171,190,246,275],"soumis":[136],"aux":[137],"rats":[138],"pendant":[139,380],"8":[140],"semaines":[141],"conduit":[142,191,279],"qui":[148,201],"se":[149],"caract\u00e9rise":[150],"l'insulin\u00e9mie":[155,251],"ainsi":[156,288,295,350,586],"qu'\u00e0":[157],"diminution":[159,174],"l'expression":[161,197,229,284,440,500],"prot\u00e9ique":[162],"r\u00e9cepteur":[164,179,199,257,286,301],"l'insuline.":[166,259],"De":[167],"plus,":[168],"provoque":[172],"sensibilit\u00e9":[177],"l'insuline":[181,211,344,568],"inhibant":[183],"son":[184],"activit\u00e9":[185,261],"tyrosine":[186,262],"kinase.":[187],"\u00e9galement":[192],"TLR4,":[200,535],"joue":[202],"r\u00f4le":[204,310],"dans":[205,312,325,338],"l'induction":[206,339],"l'interm\u00e9diaire":[213],"l'activation":[215,235],"voies":[217,292,306,335],"proinflammatoires":[218,238,293,336],"r\u00e9sistine":[221,419,464,484,530],"LPS.":[224],"l'augmentation":[227],"TLR4":[231,287,302,331,502,543,584],"associ\u00e9e":[233],"avec":[234,247,276,395,436,496],"MAPK":[237],"JNK":[239],"P38.":[241],"l'enrichissement":[243],"normalise":[250],"niveaux":[254],"d'expression":[255],"Son":[260],"kinase":[263],"aussi":[265,515],"restaur\u00e9e.":[266],"Et":[267],"d'une":[268],"mani\u00e8re":[269,452],"int\u00e9ressante,":[270,453],"suppl\u00e9mentation":[272],"r\u00e9duction":[282],"qu'une":[289],"inhibition":[290],"pr\u00e9venant":[294],"h\u00e9patique":[298],"l\u2019insuline.Le":[300],"l\u2019activation":[304],"pro-inflammatoires":[307],"jouent":[308],"important":[311],"l\u2019induction":[313],"l\u2019insuline.":[318],"Afin":[319],"d'explorer":[320],"m\u00e9canismes":[322,357],"mol\u00e9culaires":[323],"impliqu\u00e9s":[324],"r\u00e9gulation":[327,577],"l\u2019expression":[329,469,489,541],"d\u00e9terminer":[333],"impliqu\u00e9es":[337],"satur\u00e9s,":[349],"mise":[353],"\u00e9vidence":[355],"insulino-sensibilisateurs":[358],"AGPI":[360],"om\u00e9ga-3,":[361],"utilis\u00e9":[364],"cellules":[366,375],"SH-SY5Y":[367],"(cellules":[368],"neuroblastome":[370],"humain).":[371],"SHSY5Y":[376],"\u00e9t\u00e9":[378],"expos\u00e9es":[379],"4h":[381],"l\u2019acide":[383],"palmitique":[384],"(PA,":[385],"acide":[386],"satur\u00e9)":[388],"ou":[389],"au":[390,456,507,519],"DHA":[391,411,457,508],"(om\u00e9ga-3)":[392],"puis":[393],"trait\u00e9es":[394],"r\u00e9sistine.":[397,450,526],"Tout":[398],"d'abord,":[399],"analys\u00e9":[402],"l'effet":[403],"r\u00e9sistine,":[406],"PA":[408,438,461,487,498,520],"marqueurs":[414],"l'inflammation.":[416],"Seule":[417],"capable":[421],"d'activer":[422],"NFkB":[423],"augmenter":[425],"phosphorylation":[427],"d\u2019Akt":[428],"p38":[431],"MAPK.":[432],"Toutefois,":[433],"pr\u00e9traitement":[435,455,495,506,518],"augmente":[439,499],"cytokines":[442],"inflammatoires":[443],"(IL-6":[444],"TNF-a),":[446],"similaire":[447],"D\u2019une":[451],"supprime":[458],"d":[460],"pr\u00e9vient":[466],"l\u2019augmentation":[467],"d'IL-6":[470],"TNF-\u03b1.":[472],"Nous":[473,512],"ensuite":[475],"possibilit\u00e9":[478],"d'un":[479],"effet":[480,528],"synergique":[481],"entre":[482],"TLR4.":[491],"alors":[503],"n'a":[509],"aucun":[510],"effet.":[511],"potentialise":[521],"ligand":[533],"PA,":[538],"augmentant":[540],"favorise":[544],"amplifie":[546],"r\u00e9sistine.En":[551],"conclusion,":[552],"r\u00e9sultats":[554],"montrent":[555],"pr\u00e9viennent":[562],"l'inflammation":[563],"induite":[569],"via":[575],"voie":[580],"signalisation":[582],"emp\u00eachant":[585],"l\u2019installation":[587]},"counts_by_year":[],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2026-04-02T00:00:00"}