{"id":"https://openalex.org/W7147134607","doi":"https://doi.org/10.64898/2026.03.27.714269","title":"Fc receptor dependent and independent mechanisms of antibody-mediated enhancement of immune responses","display_name":"Fc receptor dependent and independent mechanisms of antibody-mediated enhancement of immune responses","publication_year":2026,"publication_date":"2026-03-31","ids":{"openalex":"https://openalex.org/W7147134607","doi":"https://doi.org/10.64898/2026.03.27.714269"},"language":"en","primary_location":{"id":"doi:10.64898/2026.03.27.714269","doi":"https://doi.org/10.64898/2026.03.27.714269","is_oa":true,"landing_page_url":"https://doi.org/10.64898/2026.03.27.714269","pdf_url":null,"source":{"id":"https://openalex.org/S4306402567","display_name":"bioRxiv (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"posted-content"},"volume":null,"type":"preprint","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://doi.org/10.64898/2026.03.27.714269","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5080917884","display_name":"Melissa Cipolla","orcid":"https://orcid.org/0000-0001-8156-2512","observed_orcids":["https://orcid.org/0000-0001-8156-2512"]},"institutions":[{"id":"https://openalex.org/I83399316","display_name":"Rockefeller University","ror":"https://ror.org/0420db125","country_code":"US","type":"education","lineage":["https://openalex.org/I83399316"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Melissa Cipolla","raw_affiliation_strings":["Laboratory of Molecular Immunology, The Rockefeller University, New York, NY, USA"],"raw_orcid":"https://orcid.org/0000-0001-8156-2512","affiliations":[{"raw_affiliation_string":"Laboratory of Molecular Immunology, The Rockefeller University, New York, NY, USA","institution_ids":["https://openalex.org/I83399316"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089541169","display_name":"Andrew J. MacLean","orcid":"https://orcid.org/0009-0008-8378-4141","observed_orcids":["https://orcid.org/0009-0008-8378-4141","https://orcid.org/0000-0003-2124-8999"]},"institutions":[{"id":"https://openalex.org/I83399316","display_name":"Rockefeller University","ror":"https://ror.org/0420db125","country_code":"US","type":"education","lineage":["https://openalex.org/I83399316"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Andrew J. MacLean","raw_affiliation_strings":["Laboratory of Molecular Immunology, The Rockefeller University, New York, NY, USA"],"raw_orcid":"https://orcid.org/0000-0003-2124-8999","affiliations":[{"raw_affiliation_string":"Laboratory of Molecular Immunology, The Rockefeller University, New York, NY, USA","institution_ids":["https://openalex.org/I83399316"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5132614184","display_name":"Brianna Hernandez","orcid":"https://orcid.org/0009-0003-8137-4353","observed_orcids":["https://orcid.org/0009-0003-8137-4353"]},"institutions":[{"id":"https://openalex.org/I83399316","display_name":"Rockefeller University","ror":"https://ror.org/0420db125","country_code":"US","type":"education","lineage":["https://openalex.org/I83399316"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Brianna Hernandez","raw_affiliation_strings":["Laboratory of Molecular Immunology, The Rockefeller University, New York, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Molecular Immunology, The Rockefeller University, New York, NY, USA","institution_ids":["https://openalex.org/I83399316"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050358212","display_name":"Gabriela S. Silva Santos","orcid":"https://orcid.org/0000-0002-7482-7380","observed_orcids":["https://orcid.org/0000-0002-7482-7380"]},"institutions":[{"id":"https://openalex.org/I83399316","display_name":"Rockefeller University","ror":"https://ror.org/0420db125","country_code":"US","type":"education","lineage":["https://openalex.org/I83399316"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gabriela S. Silva Santos","raw_affiliation_strings":["Laboratory of Molecular Immunology, The Rockefeller University, New York, NY, USA"],"raw_orcid":"https://orcid.org/0000-0002-7482-7380","affiliations":[{"raw_affiliation_string":"Laboratory of Molecular Immunology, The Rockefeller University, New York, NY, USA","institution_ids":["https://openalex.org/I83399316"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002836913","display_name":"Leonidas Stamatatos","orcid":"https://orcid.org/0000-0002-1106-7097","observed_orcids":["https://orcid.org/0000-0002-1106-7097"]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]},{"id":"https://openalex.org/I4210089486","display_name":"Fred Hutch Cancer Center","ror":"https://ror.org/007ps6h72","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210089486"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Leonidas Stamatatos","raw_affiliation_strings":["Department of Global Health, University of Washington, Seattle, WA, USA","Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, WA, USA"],"raw_orcid":"https://orcid.org/0000-0002-1106-7097","affiliations":[{"raw_affiliation_string":"Department of Global Health, University of Washington, Seattle, WA, USA","institution_ids":["https://openalex.org/I201448701"]},{"raw_affiliation_string":"Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Center, Seattle, WA, USA","institution_ids":["https://openalex.org/I4210089486"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072949815","display_name":"Anna Gazumyan","orcid":"https://orcid.org/0000-0002-5976-9717","observed_orcids":["https://orcid.org/0000-0002-5976-9717"]},"institutions":[{"id":"https://openalex.org/I83399316","display_name":"Rockefeller University","ror":"https://ror.org/0420db125","country_code":"US","type":"education","lineage":["https://openalex.org/I83399316"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Anna Gazumyan","raw_affiliation_strings":["Laboratory of Molecular Immunology, The Rockefeller University, New York, NY, USA"],"raw_orcid":"https://orcid.org/0000-0002-5976-9717","affiliations":[{"raw_affiliation_string":"Laboratory of Molecular Immunology, The Rockefeller University, New York, NY, USA","institution_ids":["https://openalex.org/I83399316"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012612358","display_name":"Harald Hartweger","orcid":"https://orcid.org/0000-0002-1118-1818","observed_orcids":["https://orcid.org/0000-0002-1118-1818"]},"institutions":[{"id":"https://openalex.org/I83399316","display_name":"Rockefeller University","ror":"https://ror.org/0420db125","country_code":"US","type":"education","lineage":["https://openalex.org/I83399316"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Harald Hartweger","raw_affiliation_strings":["Laboratory of Molecular Immunology, The Rockefeller University, New York, NY, USA"],"raw_orcid":"https://orcid.org/0000-0002-1118-1818","affiliations":[{"raw_affiliation_string":"Laboratory of Molecular Immunology, The Rockefeller University, New York, NY, USA","institution_ids":["https://openalex.org/I83399316"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024104170","display_name":"Julia Merkenschlager","orcid":"https://orcid.org/0000-0001-6726-7939","observed_orcids":["https://orcid.org/0000-0001-6726-7939"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I83399316","display_name":"Rockefeller University","ror":"https://ror.org/0420db125","country_code":"US","type":"education","lineage":["https://openalex.org/I83399316"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Julia Merkenschlager","raw_affiliation_strings":["Laboratory of Lymphocyte Collaboration and Competition, Harvard Medical School, Boston, MA, USA","Laboratory of Molecular Immunology, The Rockefeller University, New York, NY, USA"],"raw_orcid":"https://orcid.org/0000-0001-6726-7939","affiliations":[{"raw_affiliation_string":"Laboratory of Lymphocyte Collaboration and Competition, Harvard Medical School, Boston, MA, USA","institution_ids":["https://openalex.org/I136199984"]},{"raw_affiliation_string":"Laboratory of Molecular Immunology, The Rockefeller University, New York, NY, USA","institution_ids":["https://openalex.org/I83399316"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021432635","display_name":"Stylianos Bournazos","orcid":"https://orcid.org/0000-0001-5466-5620","observed_orcids":["https://orcid.org/0000-0001-5466-5620"]},"institutions":[{"id":"https://openalex.org/I83399316","display_name":"Rockefeller University","ror":"https://ror.org/0420db125","country_code":"US","type":"education","lineage":["https://openalex.org/I83399316"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Stylianos Bournazos","raw_affiliation_strings":["Laboratory of Molecular Genetics and Immunology, The Rockefeller University, New York, NY, USA"],"raw_orcid":"https://orcid.org/0000-0001-5466-5620","affiliations":[{"raw_affiliation_string":"Laboratory of Molecular Genetics and Immunology, The Rockefeller University, New York, NY, USA","institution_ids":["https://openalex.org/I83399316"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007474253","display_name":"Jeffrey V. Ravetch","orcid":"https://orcid.org/0000-0003-2024-9041","observed_orcids":["https://orcid.org/0000-0003-2024-9041"]},"institutions":[{"id":"https://openalex.org/I83399316","display_name":"Rockefeller University","ror":"https://ror.org/0420db125","country_code":"US","type":"education","lineage":["https://openalex.org/I83399316"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jeffrey V. Ravetch","raw_affiliation_strings":["Laboratory of Molecular Genetics and Immunology, The Rockefeller University, New York, NY, USA"],"raw_orcid":"https://orcid.org/0000-0003-2024-9041","affiliations":[{"raw_affiliation_string":"Laboratory of Molecular Genetics and Immunology, The Rockefeller University, New York, NY, USA","institution_ids":["https://openalex.org/I83399316"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5003699560","display_name":"Michel C. Nussenzweig","orcid":"https://orcid.org/0000-0003-0592-8564","observed_orcids":["https://orcid.org/0000-0003-0592-8564"]},"institutions":[{"id":"https://openalex.org/I1344073410","display_name":"Howard Hughes Medical Institute","ror":"https://ror.org/006w34k90","country_code":"US","type":"facility","lineage":["https://openalex.org/I1344073410"]},{"id":"https://openalex.org/I83399316","display_name":"Rockefeller University","ror":"https://ror.org/0420db125","country_code":"US","type":"education","lineage":["https://openalex.org/I83399316"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Michel C. Nussenzweig","raw_affiliation_strings":["Howard Hughes Medical Institute (HHMI), The Rockefeller University, New York, NY, USA","Laboratory of Molecular Immunology, The Rockefeller University, New York, NY, USA"],"raw_orcid":"https://orcid.org/0000-0003-0592-8564","affiliations":[{"raw_affiliation_string":"Howard Hughes Medical Institute (HHMI), The Rockefeller University, New York, NY, USA","institution_ids":["https://openalex.org/I1344073410","https://openalex.org/I83399316"]},{"raw_affiliation_string":"Laboratory of Molecular Immunology, The Rockefeller University, New York, NY, USA","institution_ids":["https://openalex.org/I83399316"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5003699560"],"corresponding_institution_ids":["https://openalex.org/I1344073410","https://openalex.org/I83399316"],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":0.788100004196167,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":0.788100004196167,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11016","display_name":"Monoclonal and Polyclonal Antibodies Research","score":0.20200000703334808,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13410","display_name":"Immune responses and vaccinations","score":0.0010000000474974513,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/antibody-mediated-enhancement","display_name":"antibody-mediated enhancement","score":0.8069999814033508},{"id":"https://openalex.org/keywords/fc-gamma-receptor","display_name":"Fc gamma receptor","score":0.8830000162124634},{"id":"https://openalex.org/keywords/complement-receptor-1","display_name":"complement receptor 1","score":0.902999997138977},{"id":"https://openalex.org/keywords/complement-receptor-2","display_name":"CR2","score":1.0},{"id":"https://openalex.org/keywords/germinal-center","display_name":"germinal center","score":0.847000002861023},{"id":"https://openalex.org/keywords/plasmablasts","display_name":"plasmablasts","score":0.9679999947547913},{"id":"https://openalex.org/keywords/immunological-memory","display_name":"immunological memory","score":0.7129999995231628},{"id":"https://openalex.org/keywords/pre-existing-antibodies","display_name":"pre-existing antibodies","score":0.7699999809265137},{"id":"https://openalex.org/keywords/b-cell-recruitment","display_name":"B cell recruitment","score":0.5490000247955322}],"concepts":[{"id":"https://openalex.org/C96926380","wikidata":"https://www.wikidata.org/wiki/Q1737968","display_name":"Germinal center","level":4,"score":0.8924999833106995},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.6230000257492065},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.5845999717712402},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.5701000094413757},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.5217000246047974},{"id":"https://openalex.org/C175773311","wikidata":"https://www.wikidata.org/wiki/Q5156412","display_name":"Complement receptor","level":4,"score":0.5056999921798706},{"id":"https://openalex.org/C2778453870","wikidata":"https://www.wikidata.org/wiki/Q188930","display_name":"B cell","level":3,"score":0.5047000050544739},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.47440001368522644},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.46889999508857727},{"id":"https://openalex.org/C2779931124","wikidata":"https://www.wikidata.org/wiki/Q417823","display_name":"Fc receptor","level":3,"score":0.46549999713897705},{"id":"https://openalex.org/C2781377902","wikidata":"https://www.wikidata.org/wiki/Q21418769","display_name":"Affinity maturation","level":3,"score":0.4307999908924103},{"id":"https://openalex.org/C2779359726","wikidata":"https://www.wikidata.org/wiki/Q1195394","display_name":"Memory B cell","level":4,"score":0.42149999737739563},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.39410001039505005},{"id":"https://openalex.org/C2909900342","wikidata":"https://www.wikidata.org/wiki/Q1616930","display_name":"Immunoglobulin Fc Fragments","level":4,"score":0.36090001463890076},{"id":"https://openalex.org/C2778474638","wikidata":"https://www.wikidata.org/wiki/Q575241","display_name":"Immune complex","level":3,"score":0.3230000138282776},{"id":"https://openalex.org/C2991763054","wikidata":"https://www.wikidata.org/wiki/Q38103695","display_name":"Immunological memory","level":4,"score":0.3118000030517578},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.3086000084877014},{"id":"https://openalex.org/C157695867","wikidata":"https://www.wikidata.org/wiki/Q1100474","display_name":"B-cell receptor","level":4,"score":0.29490000009536743},{"id":"https://openalex.org/C2776090121","wikidata":"https://www.wikidata.org/wiki/Q193529","display_name":"T cell","level":3,"score":0.29330000281333923},{"id":"https://openalex.org/C137756551","wikidata":"https://www.wikidata.org/wiki/Q2386881","display_name":"Immunoglobulin class switching","level":4,"score":0.2831000089645386},{"id":"https://openalex.org/C103474210","wikidata":"https://www.wikidata.org/wiki/Q142851","display_name":"Immune receptor","level":3,"score":0.2825999855995178},{"id":"https://openalex.org/C3018913218","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody response","level":3,"score":0.2797999978065491},{"id":"https://openalex.org/C189014844","wikidata":"https://www.wikidata.org/wiki/Q189118","display_name":"Cell type","level":3,"score":0.27390000224113464},{"id":"https://openalex.org/C145558887","wikidata":"https://www.wikidata.org/wiki/Q3832893","display_name":"B-1 cell","level":5,"score":0.2694999873638153},{"id":"https://openalex.org/C62478195","wikidata":"https://www.wikidata.org/wiki/Q828130","display_name":"Signal transduction","level":2,"score":0.26440000534057617},{"id":"https://openalex.org/C89372155","wikidata":"https://www.wikidata.org/wiki/Q420107","display_name":"Opsonin","level":3,"score":0.26269999146461487},{"id":"https://openalex.org/C111684460","wikidata":"https://www.wikidata.org/wiki/Q334848","display_name":"Complement system","level":3,"score":0.2621999979019165},{"id":"https://openalex.org/C197462201","wikidata":"https://www.wikidata.org/wiki/Q2476074","display_name":"Cell surface receptor","level":3,"score":0.2574000060558319}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.64898/2026.03.27.714269","doi":"https://doi.org/10.64898/2026.03.27.714269","is_oa":true,"landing_page_url":"https://doi.org/10.64898/2026.03.27.714269","pdf_url":null,"source":{"id":"https://openalex.org/S4306402567","display_name":"bioRxiv (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"posted-content"}],"best_oa_location":{"id":"doi:10.64898/2026.03.27.714269","doi":"https://doi.org/10.64898/2026.03.27.714269","is_oa":true,"landing_page_url":"https://doi.org/10.64898/2026.03.27.714269","pdf_url":null,"source":{"id":"https://openalex.org/S4306402567","display_name":"bioRxiv (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"posted-content"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.5683000087738037,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":66,"referenced_works":["https://openalex.org/W1482080671","https://openalex.org/W1502492318","https://openalex.org/W1965076940","https://openalex.org/W1968375364","https://openalex.org/W1968537458","https://openalex.org/W1982839060","https://openalex.org/W1985136634","https://openalex.org/W1990539976","https://openalex.org/W1991656907","https://openalex.org/W2000061036","https://openalex.org/W2003000602","https://openalex.org/W2006894378","https://openalex.org/W2016054852","https://openalex.org/W2016708646","https://openalex.org/W2023364238","https://openalex.org/W2028087680","https://openalex.org/W2036897871","https://openalex.org/W2055951388","https://openalex.org/W2062204806","https://openalex.org/W2071722434","https://openalex.org/W2072411874","https://openalex.org/W2076198413","https://openalex.org/W2076456265","https://openalex.org/W2080674820","https://openalex.org/W2081717004","https://openalex.org/W2083571966","https://openalex.org/W2083719521","https://openalex.org/W2084317828","https://openalex.org/W2091709065","https://openalex.org/W2097907807","https://openalex.org/W2100612316","https://openalex.org/W2104432354","https://openalex.org/W2110990893","https://openalex.org/W2116661011","https://openalex.org/W2118274231","https://openalex.org/W2137063023","https://openalex.org/W2138207763","https://openalex.org/W2166979142","https://openalex.org/W2169456326","https://openalex.org/W2169818150","https://openalex.org/W2171117312","https://openalex.org/W2180048932","https://openalex.org/W2527013454","https://openalex.org/W2527863850","https://openalex.org/W2580378056","https://openalex.org/W2611690321","https://openalex.org/W2795740139","https://openalex.org/W2952109315","https://openalex.org/W2989707275","https://openalex.org/W3021060601","https://openalex.org/W3044639797","https://openalex.org/W3080829022","https://openalex.org/W3128063150","https://openalex.org/W3135024921","https://openalex.org/W3137987441","https://openalex.org/W3161420752","https://openalex.org/W4289767269","https://openalex.org/W4311129803","https://openalex.org/W4312140670","https://openalex.org/W4313347699","https://openalex.org/W4375859102","https://openalex.org/W4382182059","https://openalex.org/W4382937102","https://openalex.org/W4384198553","https://openalex.org/W4402677562","https://openalex.org/W4405603466"],"related_works":["https://openalex.org/W7201842494","https://openalex.org/W2128733214","https://openalex.org/W2003000602","https://openalex.org/W2067195117","https://openalex.org/W2084839207","https://openalex.org/W1482080671","https://openalex.org/W7155063992","https://openalex.org/W4313347699","https://openalex.org/W4399360425","https://openalex.org/W1812829599"],"abstract_inverted_index":{"Abstract":[0],"Immune":[1],"memory":[2,20],"responses":[3,38,63,113,157],"are":[4],"rapid":[5],"and":[6,22,25,33,47,60,81,85,111,120,125,145,164,173],"qualitatively":[7],"distinct":[8],"from":[9],"primary":[10],"responses.":[11,102],"They":[12],"typically":[13],"develop":[14],"in":[15,133],"the":[16,29,42,48,55,86,93,131,134,171,176],"presence":[17],"of":[18,31,44,57,77,109,142,175],"antigen-experienced":[19],"T":[21,32],"B":[23,34,97],"cells":[24,35],"pre-existing":[26,52],"antibodies.":[27],"Although":[28],"contribution":[30,43],"to":[36],"recall":[37],"is":[39,64,114,140],"well":[40],"defined,":[41],"antibody":[45,75,153],"\u201cmemory\u201d":[46],"mechanisms":[49,72,168],"by":[50,89],"which":[51,90],"antibodies":[53],"modulate":[54,155],"development":[56],"germinal":[58,78,177],"center":[59,79,178],"plasma":[61],"cell":[62,98],"not":[65],"precisely":[66],"understood.":[67],"Here":[68],"we":[69],"report":[70],"on":[71],"that":[73,106,152],"mediate":[74],"enhancement":[76,108],"(GC)":[80],"plasmablast":[82],"(PB)":[83],"compartments,":[84],"parallel":[87],"process":[88],"they":[91],"change":[92],"affinity":[94,135],"threshold":[95,136],"for":[96,137],"recruitment":[99],"into":[100],"immune":[101,156],"The":[103],"data":[104],"indicate":[105],"antibody-mediated":[107],"GC":[110,138],"PB":[112],"Fc":[115,160],"gamma":[116,161],"receptor":[117,123,162],"(Fc\u03b3R)":[118],"dependent":[119,163],"largely":[121],"complement":[122],"1":[124],"2":[126],"(CR1/2)":[127],"independent.":[128],"In":[129],"contrast,":[130],"reduction":[132],"entry":[139],"independent":[141,165],"both":[143,159,170],"Fc\u03b3Rs":[144],"CR1/2.":[146],"Summary":[147],"Cipolla":[148],"et":[149],"al.":[150],"show":[151],"can":[154],"via":[158],"mechanisms.":[166],"These":[167],"influence":[169],"magnitude":[172],"composition":[174],"response.":[179]},"counts_by_year":[],"updated_date":"2026-10-28T10:33:24.094632","created_date":"2026-04-02T00:00:00"}