{"id":"https://openalex.org/W7144834291","doi":null,"title":"\u30de\u30a6\u30b9\u306e\u793e\u4f1a\u7684\u8a8d\u77e5\u6a5f\u80fd\u306b\u304a\u3051\u308b\u524d\u982d\u524d\u76ae\u8cea\u306e\u5f79\u5272","display_name":"\u30de\u30a6\u30b9\u306e\u793e\u4f1a\u7684\u8a8d\u77e5\u6a5f\u80fd\u306b\u304a\u3051\u308b\u524d\u982d\u524d\u76ae\u8cea\u306e\u5f79\u5272","publication_year":null,"publication_date":null,"ids":{"openalex":"https://openalex.org/W7144834291"},"language":"ja","primary_location":{"id":"pmh:oai:irdb.nii.ac.jp:01222:0006301317","doi":null,"is_oa":true,"landing_page_url":"https://tachibana.repo.nii.ac.jp/records/2000042","pdf_url":"https://tachibana.repo.nii.ac.jp/record/2000042/files/ktu_dr_2023_k02_b.pdf","source":{"id":"https://openalex.org/S7407056385","display_name":"Institutional Repositories DataBase (IRDB)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I184597095","host_organization_name":"National Institute of Informatics","host_organization_lineage":["https://openalex.org/I184597095"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"doctoral thesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://tachibana.repo.nii.ac.jp/record/2000042/files/ktu_dr_2023_k02_b.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5131650879","display_name":"\u6210\u7dad \u516b\u5cf6","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"\u516b\u5cf6, \u6210\u7dad","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5131650879"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11541","display_name":"Neuroendocrine regulation and behavior","score":0.9794999957084656,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11541","display_name":"Neuroendocrine regulation and behavior","score":0.9794999957084656,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10448","display_name":"Memory and Neural Mechanisms","score":0.015799999237060547,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11094","display_name":"Face Recognition and Perception","score":0.0010000000474974513,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/prefrontal-cortex","display_name":"prefrontal cortex","score":0.878000020980835},{"id":"https://openalex.org/keywords/social-cognition","display_name":"social cognition","score":0.9340000152587891},{"id":"https://openalex.org/keywords/social-memory","display_name":"social memory","score":0.8579999804496765},{"id":"https://openalex.org/keywords/social-recognition","display_name":"social recognition","score":0.8669999837875366},{"id":"https://openalex.org/keywords/social-novelty","display_name":"social novelty","score":0.8420000076293945},{"id":"https://openalex.org/keywords/social-motivation","display_name":"social motivation","score":0.8889999985694885},{"id":"https://openalex.org/keywords/oxytocin-receptor","display_name":"oxytocin receptor","score":0.6940000057220459},{"id":"https://openalex.org/keywords/oxytocin-receptor-antagonist","display_name":"oxytocin receptor antagonist","score":0.8870000243186951},{"id":"https://openalex.org/keywords/prelimbic-cortex","display_name":"prelimbic cortex","score":0.8410000205039978},{"id":"https://openalex.org/keywords/anterior-cingulate-cortex","display_name":"anterior cingulate cortex","score":0.9990000128746033},{"id":"https://openalex.org/keywords/short-term-habituation","display_name":"short-term habituation","score":0.6370000243186951},{"id":"https://openalex.org/keywords/anxiety-like-behavior","display_name":"anxiety-like behavior","score":0.656000018119812},{"id":"https://openalex.org/keywords/social-inquiry","display_name":"social investigation","score":0.5270000100135803},{"id":"https://openalex.org/keywords/mice","display_name":"mice","score":0.6859999895095825},{"id":"https://openalex.org/keywords/lesion-studies","display_name":"lesion studies","score":0.5849999785423279}],"concepts":[{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.6399999856948853},{"id":"https://openalex.org/C50610925","wikidata":"https://www.wikidata.org/wiki/Q1136816","display_name":"Habituation","level":2,"score":0.5521000027656555},{"id":"https://openalex.org/C2779085643","wikidata":"https://www.wikidata.org/wiki/Q7096029","display_name":"Open field","level":2,"score":0.5390999913215637},{"id":"https://openalex.org/C2778738651","wikidata":"https://www.wikidata.org/wiki/Q16546687","display_name":"Novelty","level":2,"score":0.5252000093460083},{"id":"https://openalex.org/C2781195155","wikidata":"https://www.wikidata.org/wiki/Q18680","display_name":"Prefrontal cortex","level":3,"score":0.4821999967098236},{"id":"https://openalex.org/C138496976","wikidata":"https://www.wikidata.org/wiki/Q175002","display_name":"Developmental psychology","level":1,"score":0.47110000252723694},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.47049999237060547},{"id":"https://openalex.org/C2781210436","wikidata":"https://www.wikidata.org/wiki/Q1892702","display_name":"Cingulate cortex","level":3,"score":0.4320000112056732},{"id":"https://openalex.org/C2776035688","wikidata":"https://www.wikidata.org/wiki/Q1606558","display_name":"Affect (linguistics)","level":2,"score":0.4172999858856201},{"id":"https://openalex.org/C86658582","wikidata":"https://www.wikidata.org/wiki/Q1432778","display_name":"Social cognition","level":3,"score":0.385699987411499},{"id":"https://openalex.org/C2993892105","wikidata":"https://www.wikidata.org/wiki/Q7302601","display_name":"Social recognition","level":2,"score":0.38429999351501465},{"id":"https://openalex.org/C2776176026","wikidata":"https://www.wikidata.org/wiki/Q169960","display_name":"Oxytocin","level":2,"score":0.3774999976158142},{"id":"https://openalex.org/C2778402161","wikidata":"https://www.wikidata.org/wiki/Q2121931","display_name":"Anterior cingulate cortex","level":3,"score":0.36820000410079956},{"id":"https://openalex.org/C169900460","wikidata":"https://www.wikidata.org/wiki/Q2200417","display_name":"Cognition","level":2,"score":0.3407000005245209},{"id":"https://openalex.org/C2776893239","wikidata":"https://www.wikidata.org/wiki/Q1778765","display_name":"Social isolation","level":2,"score":0.32899999618530273},{"id":"https://openalex.org/C13543017","wikidata":"https://www.wikidata.org/wiki/Q4430231","display_name":"Social deprivation","level":2,"score":0.3253999948501587},{"id":"https://openalex.org/C130064352","wikidata":"https://www.wikidata.org/wiki/Q853725","display_name":"Social relation","level":2,"score":0.3249000012874603},{"id":"https://openalex.org/C118303440","wikidata":"https://www.wikidata.org/wiki/Q419968","display_name":"Neuropeptide","level":3,"score":0.30570000410079956},{"id":"https://openalex.org/C21204594","wikidata":"https://www.wikidata.org/wiki/Q921513","display_name":"Social behavior","level":2,"score":0.27459999918937683},{"id":"https://openalex.org/C16634123","wikidata":"https://www.wikidata.org/wiki/Q7551393","display_name":"Social stress","level":2,"score":0.2678999900817871},{"id":"https://openalex.org/C115961737","wikidata":"https://www.wikidata.org/wiki/Q1516282","display_name":"Juvenile","level":2,"score":0.26080000400543213}],"mesh":[],"locations_count":1,"locations":[{"id":"pmh:oai:irdb.nii.ac.jp:01222:0006301317","doi":null,"is_oa":true,"landing_page_url":"https://tachibana.repo.nii.ac.jp/records/2000042","pdf_url":"https://tachibana.repo.nii.ac.jp/record/2000042/files/ktu_dr_2023_k02_b.pdf","source":{"id":"https://openalex.org/S7407056385","display_name":"Institutional Repositories DataBase (IRDB)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I184597095","host_organization_name":"National Institute of Informatics","host_organization_lineage":["https://openalex.org/I184597095"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"doctoral thesis"}],"best_oa_location":{"id":"pmh:oai:irdb.nii.ac.jp:01222:0006301317","doi":null,"is_oa":true,"landing_page_url":"https://tachibana.repo.nii.ac.jp/records/2000042","pdf_url":"https://tachibana.repo.nii.ac.jp/record/2000042/files/ktu_dr_2023_k02_b.pdf","source":{"id":"https://openalex.org/S7407056385","display_name":"Institutional Repositories DataBase (IRDB)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I184597095","host_organization_name":"National Institute of Informatics","host_organization_lineage":["https://openalex.org/I184597095"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"doctoral thesis"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7144834291.pdf","grobid_xml":"https://content.openalex.org/works/W7144834291.grobid-xml"},"referenced_works_count":114,"referenced_works":["https://openalex.org/W581256308","https://openalex.org/W829173880","https://openalex.org/W1518543521","https://openalex.org/W1541267199","https://openalex.org/W1602757251","https://openalex.org/W1965464977","https://openalex.org/W1977514547","https://openalex.org/W1982578614","https://openalex.org/W1985661446","https://openalex.org/W1997603362","https://openalex.org/W2003392460","https://openalex.org/W2008763209","https://openalex.org/W2008860212","https://openalex.org/W2011010963","https://openalex.org/W2011504521","https://openalex.org/W2019807914","https://openalex.org/W2023976995","https://openalex.org/W2033268764","https://openalex.org/W2035177057","https://openalex.org/W2035462451","https://openalex.org/W2035895525","https://openalex.org/W2036309829","https://openalex.org/W2037594700","https://openalex.org/W2055165429","https://openalex.org/W2058233450","https://openalex.org/W2061706174","https://openalex.org/W2065380220","https://openalex.org/W2067545661","https://openalex.org/W2069519651","https://openalex.org/W2069667743","https://openalex.org/W2072652550","https://openalex.org/W2075052558","https://openalex.org/W2076566560","https://openalex.org/W2082887417","https://openalex.org/W2084677746","https://openalex.org/W2084882106","https://openalex.org/W2087129491","https://openalex.org/W2091028497","https://openalex.org/W2091234323","https://openalex.org/W2091281681","https://openalex.org/W2096484229","https://openalex.org/W2099168883","https://openalex.org/W2103264859","https://openalex.org/W2109091674","https://openalex.org/W2110037546","https://openalex.org/W2121825607","https://openalex.org/W2136061660","https://openalex.org/W2148097152","https://openalex.org/W2148891332","https://openalex.org/W2150681219","https://openalex.org/W2158994451","https://openalex.org/W2162459454","https://openalex.org/W2164537043","https://openalex.org/W2164671673","https://openalex.org/W2165266294","https://openalex.org/W2166273490","https://openalex.org/W2167872172","https://openalex.org/W2170097553","https://openalex.org/W2173670840","https://openalex.org/W2184917663","https://openalex.org/W2192963222","https://openalex.org/W2217656301","https://openalex.org/W2279203193","https://openalex.org/W2490698326","https://openalex.org/W2517333721","https://openalex.org/W2525578234","https://openalex.org/W2526508243","https://openalex.org/W2606136976","https://openalex.org/W2625169251","https://openalex.org/W2672878424","https://openalex.org/W2741054042","https://openalex.org/W2767851849","https://openalex.org/W2772417881","https://openalex.org/W2778920599","https://openalex.org/W2795455408","https://openalex.org/W2799513798","https://openalex.org/W2802046728","https://openalex.org/W2804267430","https://openalex.org/W2810620216","https://openalex.org/W2895003314","https://openalex.org/W2895687586","https://openalex.org/W2896605400","https://openalex.org/W2908730501","https://openalex.org/W2917785150","https://openalex.org/W2937223937","https://openalex.org/W2942558631","https://openalex.org/W2945129130","https://openalex.org/W2949112906","https://openalex.org/W2951493639","https://openalex.org/W2955865427","https://openalex.org/W2994049374","https://openalex.org/W2995438719","https://openalex.org/W2997912864","https://openalex.org/W3004431803","https://openalex.org/W3005544203","https://openalex.org/W3015947217","https://openalex.org/W3043022139","https://openalex.org/W3047544314","https://openalex.org/W3083031599","https://openalex.org/W3087402181","https://openalex.org/W3136859047","https://openalex.org/W3149736664","https://openalex.org/W3159995594","https://openalex.org/W3160186986","https://openalex.org/W3163969335","https://openalex.org/W3207566007","https://openalex.org/W3210700420","https://openalex.org/W4206648006","https://openalex.org/W4221093782","https://openalex.org/W4284989910","https://openalex.org/W4292338349","https://openalex.org/W4293783072","https://openalex.org/W4387318339","https://openalex.org/W7098584608"],"related_works":["https://openalex.org/W4366603586","https://openalex.org/W4292338349","https://openalex.org/W4387394290","https://openalex.org/W3163915889","https://openalex.org/W3083031599","https://openalex.org/W2917785150","https://openalex.org/W3089103715","https://openalex.org/W3174475603","https://openalex.org/W4392752834","https://openalex.org/W2969513567"],"abstract_inverted_index":{"Introduction.":[0],"Social":[1],"cognitive":[2,28,40,458,479,520],"functions":[3,41,459,480,521,551],"are":[4,481],"regulated":[5],"on":[6,45,257,329,361,377,452,461,465,525],"neural":[7,36,454,474,499,516],"circuits":[8],"among":[9],"brain":[10],"regions":[11],"such":[12],"as":[13,91,93,117,150,186],"prefrontal":[14],"cortex":[15,66,71],"(PFC),":[16],"hippocampus,":[17],"amygdala,":[18],"and":[19,51,68,79,105,111,124,158,199,205,218,243,259,286,306,364,368,405,468,494,552],"others.":[20],"Furthermore,":[21,202,389],"the":[22,35,46,52,58,61,64,101,120,129,133,161,178,214,222,229,233,249,255,271,281,298,302,307,338,342,353,362,365,369,379,390,401,409,414,424,438,453,462,473,483,501,515,526,539],"neuropeptide":[23],"oxytocin":[24,252,266,435],"involved":[25,476],"in":[26,42,73,82,95,173,213,221,239,254,273,358,374,400,408,437,443,477,491,557],"social":[27,39,49,75,77,102,106,118,130,151,162,174,187,197,200,241,244,261,299,318,339,429,445,457,478,492,495,519,530],"functions.":[29],"In":[30,128,160,337,351,413,497,528],"this":[31,498],"study,":[32,416],"we":[33,417],"examine":[34,514],"mechanisms":[37,553],"of":[38,60,142,251,325,334,392,421,456,518,542],"rodents,":[43],"focusing":[44],"relationship":[47],"between":[48],"memory":[50,493,531],"PFC.":[53,527],"Study":[54,246],"1.":[55],"We":[56,226,263,448],"examined":[57,248],"role":[59,238,250,490],"PFC":[62,256,272,425,439,502],"subregions,":[63],"prelimbic":[65],"(PL)":[67],"anterior":[69],"cingulate":[70],"(ACC),":[72],"short-term":[74,240,347,359,375,428,444],"memory,":[76],"motivation,":[78],"anxiety-related":[80,219,406],"behaviors":[81],"male":[83,113,274],"mice.":[84,275],"The":[85,276,317],"PL":[86,193,203,230],"or":[87,145],"ACC":[88,153,206,234],"lesioned":[89],"group,":[90,99],"well":[92],"those":[94],"a":[96,450,523],"sham":[97],"control":[98,179,288,343],"underwent":[100,297],"recognition":[103,131,198,242,300,319,340],"test":[104,108,123,217,310,320,404],"novelty":[107,163],"where":[109],"juvenile":[110,144],"adult":[112,146,182],"mice":[114,135,147,168,180,183,277,296],"were":[115,148,184,278],"used":[116,149,185],"stimuli,":[119],"open":[121,215,303,402],"field":[122,216,304,403],"light-dark":[125,223,410],"transition":[126,224,309,411],"test.":[127,225,412],"test,":[132,164,301,305,341],"PL-lesioned":[134],"exhibited":[136,346],"habituation":[137,157,348,360,376],"but":[138,231],"not":[139,166,209,232,385,396,533],"dishabituation":[140],"regardless":[141],"whether":[143],"stimuli.":[152,188],"lesions":[154,194,204,207],"didn\u2019t":[155],"affect":[156,210,397],"dishabituation.":[159],"PL-but":[165],"ACC-lesioned":[167],"spent":[169],"less":[170],"time":[171],"engaged":[172],"investigation":[175],"compared":[176],"with":[177,522],"when":[181],"These":[189],"results":[190],"suggest":[191],"that":[192,419,434,548],"impaired":[195,427],"both":[196],"motivation.":[201,245,496],"did":[208,384,395],"general":[211,398],"activity":[212,399],"behavior":[220,407],"newly":[227],"found":[228,418],"plays":[235],"an":[236,265,488],"important":[237,441],"2.We":[247],"receptors":[253,436],"short-":[258],"long-term":[260,387],"memory.":[262,430,446],"injected":[264],"receptor":[267],"antagonist":[268],"(OTA)":[269],"into":[270,280,423],"divided":[279],"high-dose":[282],"OTA,":[283],"low-dose":[284],"OTA":[285,393,422],"vehicle":[287],"group":[289,344,355,371,383],"(artificial":[290],"cerebrospinal":[291],"fluid:":[292],"aCSF).":[293],"All":[294],"grouped":[295],"light/dark":[308],"15":[311],"min":[312,327],"after":[313],"each":[314,328,349],"drug":[315],"injection.":[316],"was":[321],"conducted":[322],"three":[323],"trials":[324],"5":[326],"3":[330],"consecutive":[331],"days":[332],"(total":[333],"9":[335],"trials).":[336],"showed":[345,356,372],"day.":[350,381],"contrast,":[352],"OTA-H":[354],"impairment":[357,373],"2nd":[363],"3rd":[366,380],"days,":[367],"OTA-L":[370],"only":[378],"Each":[382],"show":[386],"habituation.":[388],"effects":[391],"injection":[394,420],"present":[415],"dose-dependently":[426],"Our":[431],"findings":[432],"demonstrated":[433],"played":[440],"roles":[442],"Discussion.":[447],"provided":[449],"perspective":[451],"network":[455],"centered":[460],"PFC,":[463],"based":[464],"previous":[466],"studies":[467],"our":[469],"two":[470],"studies.":[471,543],"Although":[472],"networks":[475],"unclear,":[482],"PFC-amygdala-hippocampal":[484],"circuit":[485],"might":[486,503],"play":[487],"essential":[489],"circuit,":[500],"perform":[504],"top-down":[505],"processing;":[506],"thus,":[507],"it":[508,545],"is":[509,546],"necessary":[510],"to":[511,513,538],"continue":[512],"basis":[517],"focus":[524],"addition,":[529],"has":[532],"been":[534],"studied":[535,556],"systematically":[536],"due":[537],"small":[540],"number":[541],"Therefore,":[544],"expected":[547],"their":[549],"various":[550],"will":[554],"be":[555],"more":[558],"detail.":[559]},"counts_by_year":[],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2026-04-01T00:00:00"}