{"id":"https://openalex.org/W7143346128","doi":"https://doi.org/10.1038/s41380-026-03535-1","title":"Circuit-targeted modulation of anxiety symptoms in individuals with major depression: A randomized head-to-head TMS trial","display_name":"Circuit-targeted modulation of anxiety symptoms in individuals with major depression: A randomized head-to-head TMS trial","publication_year":2026,"publication_date":"2026-03-30","ids":{"openalex":"https://openalex.org/W7143346128","doi":"https://doi.org/10.1038/s41380-026-03535-1","pmid":"https://pubmed.ncbi.nlm.nih.gov/41912790","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/13098680"},"language":"en","primary_location":{"id":"doi:10.1038/s41380-026-03535-1","doi":"https://doi.org/10.1038/s41380-026-03535-1","is_oa":false,"landing_page_url":"https://doi.org/10.1038/s41380-026-03535-1","pdf_url":null,"source":{"id":"https://openalex.org/S71149355","display_name":"Molecular Psychiatry","issn_l":"1359-4184","issn":["1359-4184","1476-5578"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular Psychiatry","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.researchsquare.com/article/rs-4791291/latest.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5090664383","display_name":"Joseph J. Taylor","orcid":"https://orcid.org/0000-0002-9185-0427","observed_orcids":["https://orcid.org/0000-0002-9185-0427"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I48633490","display_name":"Mass General Brigham","ror":"https://ror.org/04py2rh25","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Joseph J. Taylor","raw_affiliation_strings":["Center for Brain Circuit Therapeutics, Mass General Brigham, Boston, MA, USA. jtaylor61@bwh.harvard.edu","Department of Psychiatry, Mass General Brigham, Boston, MA, USA. jtaylor61@bwh.harvard.edu","Harvard Medical School, Boston, MA, USA. jtaylor61@bwh.harvard.edu"],"raw_orcid":"https://orcid.org/0000-0002-9185-0427","affiliations":[{"raw_affiliation_string":"Center for Brain Circuit Therapeutics, Mass General Brigham, Boston, MA, USA. jtaylor61@bwh.harvard.edu","institution_ids":["https://openalex.org/I48633490"]},{"raw_affiliation_string":"Department of Psychiatry, Mass General Brigham, Boston, MA, USA. jtaylor61@bwh.harvard.edu","institution_ids":["https://openalex.org/I48633490"]},{"raw_affiliation_string":"Harvard Medical School, Boston, MA, USA. jtaylor61@bwh.harvard.edu","institution_ids":["https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100337043","display_name":"Jing Li","orcid":"https://orcid.org/0000-0003-0410-6673","observed_orcids":["https://orcid.org/0000-0003-0410-6673"]},"institutions":[{"id":"https://openalex.org/I48633490","display_name":"Mass General Brigham","ror":"https://ror.org/04py2rh25","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jing Li","raw_affiliation_strings":["Center for Brain Circuit Therapeutics, Mass General Brigham, Boston, MA, USA","Department of Neurology, Mass General Brigham, Boston, MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Brain Circuit Therapeutics, Mass General Brigham, Boston, MA, USA","institution_ids":["https://openalex.org/I48633490"]},{"raw_affiliation_string":"Department of Neurology, Mass General Brigham, Boston, MA, USA","institution_ids":["https://openalex.org/I48633490"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006778261","display_name":"Christopher Lin","orcid":"https://orcid.org/0009-0000-0913-2390","observed_orcids":["https://orcid.org/0009-0000-0913-2390","https://orcid.org/0000-0003-2428-9980"]},"institutions":[{"id":"https://openalex.org/I48633490","display_name":"Mass General Brigham","ror":"https://ror.org/04py2rh25","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Christopher Lin","raw_affiliation_strings":["Center for Brain Circuit Therapeutics, Mass General Brigham, Boston, MA, USA","Department of Neurology, Mass General Brigham, Boston, MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Brain Circuit Therapeutics, Mass General Brigham, Boston, MA, USA","institution_ids":["https://openalex.org/I48633490"]},{"raw_affiliation_string":"Department of Neurology, Mass General Brigham, Boston, MA, USA","institution_ids":["https://openalex.org/I48633490"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5130910706","display_name":"Emma Jones","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I48633490","display_name":"Mass General Brigham","ror":"https://ror.org/04py2rh25","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Emma Jones","raw_affiliation_strings":["Center for Brain Circuit Therapeutics, Mass General Brigham, Boston, MA, USA","Department of Psychiatry, Mass General Brigham, Boston, MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Brain Circuit Therapeutics, Mass General Brigham, Boston, MA, USA","institution_ids":["https://openalex.org/I48633490"]},{"raw_affiliation_string":"Department of Psychiatry, Mass General Brigham, Boston, MA, USA","institution_ids":["https://openalex.org/I48633490"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000028681","display_name":"Summer B. Frandsen","orcid":"https://orcid.org/0000-0003-0306-3018","observed_orcids":["https://orcid.org/0000-0003-0306-3018"]},"institutions":[{"id":"https://openalex.org/I48633490","display_name":"Mass General Brigham","ror":"https://ror.org/04py2rh25","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Summer Frandsen","raw_affiliation_strings":["Center for Brain Circuit Therapeutics, Mass General Brigham, Boston, MA, USA","Department of Neurology, Mass General Brigham, Boston, MA, USA"],"raw_orcid":"https://orcid.org/0000-0003-0306-3018","affiliations":[{"raw_affiliation_string":"Center for Brain Circuit Therapeutics, Mass General Brigham, Boston, MA, USA","institution_ids":["https://openalex.org/I48633490"]},{"raw_affiliation_string":"Department of Neurology, Mass General Brigham, Boston, MA, USA","institution_ids":["https://openalex.org/I48633490"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102746361","display_name":"Claudia R. Becker","orcid":"https://orcid.org/0009-0003-1239-8650","observed_orcids":["https://orcid.org/0009-0003-1239-8650"]},"institutions":[{"id":"https://openalex.org/I91045830","display_name":"Texas A&M University","ror":"https://ror.org/01f5ytq51","country_code":"US","type":"education","lineage":["https://openalex.org/I91045830"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Claudia R. Becker","raw_affiliation_strings":["Department of Psychological and Brain Sciences, Texas A & M University, College Station, TX, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychological and Brain Sciences, Texas A & M University, College Station, TX, USA","institution_ids":["https://openalex.org/I91045830"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5129419175","display_name":"William Drew","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I48633490","display_name":"Mass General Brigham","ror":"https://ror.org/04py2rh25","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"William Drew","raw_affiliation_strings":["Center for Brain Circuit Therapeutics, Mass General Brigham, Boston, MA, USA","Department of Neurology, Mass General Brigham, Boston, MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Brain Circuit Therapeutics, Mass General Brigham, Boston, MA, USA","institution_ids":["https://openalex.org/I48633490"]},{"raw_affiliation_string":"Department of Neurology, Mass General Brigham, Boston, MA, USA","institution_ids":["https://openalex.org/I48633490"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002843074","display_name":"Dania Haj-Darwish","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I48633490","display_name":"Mass General Brigham","ror":"https://ror.org/04py2rh25","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Dania Haj-Darwish","raw_affiliation_strings":["Center for Brain Circuit Therapeutics, Mass General Brigham, Boston, MA, USA","Department of Neurology, Mass General Brigham, Boston, MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Brain Circuit Therapeutics, Mass General Brigham, Boston, MA, USA","institution_ids":["https://openalex.org/I48633490"]},{"raw_affiliation_string":"Department of Neurology, Mass General Brigham, Boston, MA, USA","institution_ids":["https://openalex.org/I48633490"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025800076","display_name":"Sandrine Jabbour","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I48633490","display_name":"Mass General Brigham","ror":"https://ror.org/04py2rh25","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sandrine Jabbour","raw_affiliation_strings":["Center for Brain Circuit Therapeutics, Mass General Brigham, Boston, MA, USA","Department of Neurology, Mass General Brigham, Boston, MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Brain Circuit Therapeutics, Mass General Brigham, Boston, MA, USA","institution_ids":["https://openalex.org/I48633490"]},{"raw_affiliation_string":"Department of Neurology, Mass General Brigham, Boston, MA, USA","institution_ids":["https://openalex.org/I48633490"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103688793","display_name":"Jessica Leach","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I48633490","display_name":"Mass General Brigham","ror":"https://ror.org/04py2rh25","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jessica Leach","raw_affiliation_strings":["Center for Brain Circuit Therapeutics, Mass General Brigham, Boston, MA, USA","Department of Neurology, Mass General Brigham, Boston, MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Brain Circuit Therapeutics, Mass General Brigham, Boston, MA, USA","institution_ids":["https://openalex.org/I48633490"]},{"raw_affiliation_string":"Department of Neurology, Mass General Brigham, Boston, MA, USA","institution_ids":["https://openalex.org/I48633490"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062218231","display_name":"Stephan T. Palm","orcid":"https://orcid.org/0009-0000-8345-5470","observed_orcids":["https://orcid.org/0009-0000-8345-5470"]},"institutions":[{"id":"https://openalex.org/I48633490","display_name":"Mass General Brigham","ror":"https://ror.org/04py2rh25","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Stephan Palm","raw_affiliation_strings":["Center for Brain Circuit Therapeutics, Mass General Brigham, Boston, MA, USA","Department of Neurology, Mass General Brigham, Boston, MA, USA"],"raw_orcid":"https://orcid.org/0009-0000-8345-5470","affiliations":[{"raw_affiliation_string":"Center for Brain Circuit Therapeutics, Mass General Brigham, Boston, MA, USA","institution_ids":["https://openalex.org/I48633490"]},{"raw_affiliation_string":"Department of Neurology, Mass General Brigham, Boston, MA, USA","institution_ids":["https://openalex.org/I48633490"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113411672","display_name":"Lauren L. Sanderson","orcid":"https://orcid.org/0000-0001-9436-0776","observed_orcids":["https://orcid.org/0000-0001-9436-0776"]},"institutions":[{"id":"https://openalex.org/I48633490","display_name":"Mass General Brigham","ror":"https://ror.org/04py2rh25","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lauren Sanderson","raw_affiliation_strings":["Center for Brain Circuit Therapeutics, Mass General Brigham, Boston, MA, USA","Department of Neurology, Mass General Brigham, Boston, MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Brain Circuit Therapeutics, Mass General Brigham, Boston, MA, USA","institution_ids":["https://openalex.org/I48633490"]},{"raw_affiliation_string":"Department of Neurology, Mass General Brigham, Boston, MA, USA","institution_ids":["https://openalex.org/I48633490"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5114237794","display_name":"Emanuella Santos","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I48633490","display_name":"Mass General Brigham","ror":"https://ror.org/04py2rh25","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Emanuella Santos","raw_affiliation_strings":["Center for Brain Circuit Therapeutics, Mass General Brigham, Boston, MA, USA","Department of Neurology, Mass General Brigham, Boston, MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Brain Circuit Therapeutics, Mass General Brigham, Boston, MA, USA","institution_ids":["https://openalex.org/I48633490"]},{"raw_affiliation_string":"Department of Neurology, Mass General Brigham, Boston, MA, USA","institution_ids":["https://openalex.org/I48633490"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5107674840","display_name":"Lera Sterina","orcid":"https://orcid.org/0009-0006-6154-1486","observed_orcids":["https://orcid.org/0009-0006-6154-1486"]},"institutions":[{"id":"https://openalex.org/I48633490","display_name":"Mass General Brigham","ror":"https://ror.org/04py2rh25","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lera Sterina","raw_affiliation_strings":["Center for Brain Circuit Therapeutics, Mass General Brigham, Boston, MA, USA","Department of Psychiatry, Mass General Brigham, Boston, MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Brain Circuit Therapeutics, Mass General Brigham, Boston, MA, USA","institution_ids":["https://openalex.org/I48633490"]},{"raw_affiliation_string":"Department of Psychiatry, Mass General Brigham, Boston, MA, USA","institution_ids":["https://openalex.org/I48633490"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5116419045","display_name":"Nicole Chiulli","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I48633490","display_name":"Mass General Brigham","ror":"https://ror.org/04py2rh25","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Nicole Chiulli","raw_affiliation_strings":["Center for Brain Circuit Therapeutics, Mass General Brigham, Boston, MA, USA","Department of Psychiatry, Mass General Brigham, Boston, MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Brain Circuit Therapeutics, Mass General Brigham, Boston, MA, USA","institution_ids":["https://openalex.org/I48633490"]},{"raw_affiliation_string":"Department of Psychiatry, Mass General Brigham, Boston, MA, USA","institution_ids":["https://openalex.org/I48633490"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050971382","display_name":"John B. Miller","orcid":"https://orcid.org/0000-0003-0109-9738","observed_orcids":["https://orcid.org/0000-0003-0109-9738"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I48633490","display_name":"Mass General Brigham","ror":"https://ror.org/04py2rh25","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"John Miller","raw_affiliation_strings":["Department of Neurology, Mass General Brigham, Boston, MA, USA","Harvard Medical School, Boston, MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, Mass General Brigham, Boston, MA, USA","institution_ids":["https://openalex.org/I48633490"]},{"raw_affiliation_string":"Harvard Medical School, Boston, MA, USA","institution_ids":["https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5130971088","display_name":"Sheena Barantono","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I48633490","display_name":"Mass General Brigham","ror":"https://ror.org/04py2rh25","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sheena Barantono","raw_affiliation_strings":["Center for Brain Circuit Therapeutics, Mass General Brigham, Boston, MA, USA","Department of Neurology, Mass General Brigham, Boston, MA, USA","Harvard Medical School, Boston, MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Brain Circuit Therapeutics, Mass General Brigham, Boston, MA, USA","institution_ids":["https://openalex.org/I48633490"]},{"raw_affiliation_string":"Department of Neurology, Mass General Brigham, Boston, MA, USA","institution_ids":["https://openalex.org/I48633490"]},{"raw_affiliation_string":"Harvard Medical School, Boston, MA, USA","institution_ids":["https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063490841","display_name":"Irene Gonsalvez","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I48633490","display_name":"Mass General Brigham","ror":"https://ror.org/04py2rh25","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Irene Gonsalvez","raw_affiliation_strings":["Center for Brain Circuit Therapeutics, Mass General Brigham, Boston, MA, USA","Department of Psychiatry, Mass General Brigham, Boston, MA, USA","Harvard Medical School, Boston, MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Brain Circuit Therapeutics, Mass General Brigham, Boston, MA, USA","institution_ids":["https://openalex.org/I48633490"]},{"raw_affiliation_string":"Department of Psychiatry, Mass General Brigham, Boston, MA, USA","institution_ids":["https://openalex.org/I48633490"]},{"raw_affiliation_string":"Harvard Medical School, Boston, MA, USA","institution_ids":["https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087782670","display_name":"Stanley Lyndon","orcid":"https://orcid.org/0000-0002-2651-9754","observed_orcids":["https://orcid.org/0000-0002-2651-9754"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I48633490","display_name":"Mass General Brigham","ror":"https://ror.org/04py2rh25","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Stanley Lyndon","raw_affiliation_strings":["Center for Brain Circuit Therapeutics, Mass General Brigham, Boston, MA, USA","Department of Psychiatry, Mass General Brigham, Boston, MA, USA","Harvard Medical School, Boston, MA, USA"],"raw_orcid":"https://orcid.org/0000-0002-2651-9754","affiliations":[{"raw_affiliation_string":"Center for Brain Circuit Therapeutics, Mass General Brigham, Boston, MA, USA","institution_ids":["https://openalex.org/I48633490"]},{"raw_affiliation_string":"Department of Psychiatry, Mass General Brigham, Boston, MA, USA","institution_ids":["https://openalex.org/I48633490"]},{"raw_affiliation_string":"Harvard Medical School, Boston, MA, USA","institution_ids":["https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073848713","display_name":"Samuel B. Snider","orcid":"https://orcid.org/0000-0002-6965-7890","observed_orcids":["https://orcid.org/0000-0002-6965-7890"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I48633490","display_name":"Mass General Brigham","ror":"https://ror.org/04py2rh25","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Samuel B. Snider","raw_affiliation_strings":["Center for Brain Circuit Therapeutics, Mass General Brigham, Boston, MA, USA","Department of Neurology, Mass General Brigham, Boston, MA, USA","Harvard Medical School, Boston, MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Brain Circuit Therapeutics, Mass General Brigham, Boston, MA, USA","institution_ids":["https://openalex.org/I48633490"]},{"raw_affiliation_string":"Department of Neurology, Mass General Brigham, Boston, MA, USA","institution_ids":["https://openalex.org/I48633490"]},{"raw_affiliation_string":"Harvard Medical School, Boston, MA, USA","institution_ids":["https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091678814","display_name":"Michael Fox","orcid":"https://orcid.org/0000-0001-8848-6399","observed_orcids":["https://orcid.org/0000-0001-8848-6399"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I48633490","display_name":"Mass General Brigham","ror":"https://ror.org/04py2rh25","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Michael D. Fox","raw_affiliation_strings":["Center for Brain Circuit Therapeutics, Mass General Brigham, Boston, MA, USA","Department of Neurology, Mass General Brigham, Boston, MA, USA","Department of Psychiatry, Mass General Brigham, Boston, MA, USA","Harvard Medical School, Boston, MA, USA"],"raw_orcid":"https://orcid.org/0000-0001-8848-6399","affiliations":[{"raw_affiliation_string":"Center for Brain Circuit Therapeutics, Mass General Brigham, Boston, MA, USA","institution_ids":["https://openalex.org/I48633490"]},{"raw_affiliation_string":"Department of Neurology, Mass General Brigham, Boston, MA, USA","institution_ids":["https://openalex.org/I48633490"]},{"raw_affiliation_string":"Department of Psychiatry, Mass General Brigham, Boston, MA, USA","institution_ids":["https://openalex.org/I48633490"]},{"raw_affiliation_string":"Harvard Medical School, Boston, MA, USA","institution_ids":["https://openalex.org/I136199984"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5039000139","display_name":"Shan Siddiqi","orcid":"https://orcid.org/0000-0002-0967-9289","observed_orcids":["https://orcid.org/0000-0002-0967-9289"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I48633490","display_name":"Mass General Brigham","ror":"https://ror.org/04py2rh25","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Shan H. Siddiqi","raw_affiliation_strings":["Center for Brain Circuit Therapeutics, Mass General Brigham, Boston, MA, USA","Department of Psychiatry, Mass General Brigham, Boston, MA, USA","Harvard Medical School, Boston, MA, USA"],"raw_orcid":"https://orcid.org/0000-0002-0967-9289","affiliations":[{"raw_affiliation_string":"Center for Brain Circuit Therapeutics, Mass General Brigham, Boston, MA, USA","institution_ids":["https://openalex.org/I48633490"]},{"raw_affiliation_string":"Department of Psychiatry, Mass General Brigham, Boston, MA, USA","institution_ids":["https://openalex.org/I48633490"]},{"raw_affiliation_string":"Harvard Medical School, Boston, MA, USA","institution_ids":["https://openalex.org/I136199984"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5090664383"],"corresponding_institution_ids":["https://openalex.org/I136199984","https://openalex.org/I48633490"],"apc_list":{"value":5490,"currency":"USD","value_usd":5490},"apc_paid":null,"fwci":41.9531,"has_fulltext":true,"cited_by_count":25,"citation_normalized_percentile":{"value":0.99894525,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":100},"biblio":{"volume":"31","issue":"8","first_page":"4525","last_page":"4534"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10614","display_name":"Transcranial Magnetic Stimulation Studies","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10614","display_name":"Transcranial Magnetic Stimulation Studies","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11071","display_name":"Treatment of Major Depression","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11921","display_name":"Electroconvulsive Therapy Studies","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/transcranial-magnetic-stimulation","display_name":"transcranial magnetic stimulation","score":0.9879999756813049},{"id":"https://openalex.org/keywords/major-depressive-disorder","display_name":"major depressive disorder","score":0.9850000143051147},{"id":"https://openalex.org/keywords/comorbid-anxiety","display_name":"anxiety comorbidity","score":0.8460000157356262},{"id":"https://openalex.org/keywords/dorsolateral-prefrontal-cortex","display_name":"dorsolateral prefrontal cortex","score":0.984000027179718},{"id":"https://openalex.org/keywords/dorsomedial-prefrontal-cortex","display_name":"dorsomedial prefrontal cortex","score":1.0},{"id":"https://openalex.org/keywords/dysphoric-symptoms","display_name":"dysphoric symptoms","score":0.8980000019073486},{"id":"https://openalex.org/keywords/placebo-controlled-comparison","display_name":"placebo comparison","score":0.4569999873638153}],"concepts":[{"id":"https://openalex.org/C2778581513","wikidata":"https://www.wikidata.org/wiki/Q263962","display_name":"Transcranial magnetic stimulation","level":3,"score":0.7562000155448914},{"id":"https://openalex.org/C558461103","wikidata":"https://www.wikidata.org/wiki/Q154430","display_name":"Anxiety","level":2,"score":0.7164999842643738},{"id":"https://openalex.org/C2776867660","wikidata":"https://www.wikidata.org/wiki/Q1814941","display_name":"Depression (economics)","level":2,"score":0.6377999782562256},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.5503000020980835},{"id":"https://openalex.org/C2780508717","wikidata":"https://www.wikidata.org/wiki/Q72788","display_name":"Dorsolateral prefrontal cortex","level":4,"score":0.5306000113487244},{"id":"https://openalex.org/C2780051608","wikidata":"https://www.wikidata.org/wiki/Q42844","display_name":"Major depressive disorder","level":3,"score":0.4424999952316284},{"id":"https://openalex.org/C2781195155","wikidata":"https://www.wikidata.org/wiki/Q18680","display_name":"Prefrontal cortex","level":3,"score":0.43779999017715454},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.43709999322891235},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.39480000734329224},{"id":"https://openalex.org/C2780375056","wikidata":"https://www.wikidata.org/wiki/Q905905","display_name":"Neuromodulation","level":3,"score":0.3434000015258789},{"id":"https://openalex.org/C3019858935","wikidata":"https://www.wikidata.org/wiki/Q4340209","display_name":"Depressive symptoms","level":3,"score":0.335999995470047},{"id":"https://openalex.org/C50231774","wikidata":"https://www.wikidata.org/wiki/Q639842","display_name":"Brain mapping","level":2,"score":0.32989999651908875},{"id":"https://openalex.org/C16568411","wikidata":"https://www.wikidata.org/wiki/Q83042","display_name":"Neurology","level":2,"score":0.32440000772476196},{"id":"https://openalex.org/C168563851","wikidata":"https://www.wikidata.org/wiki/Q1436668","display_name":"Randomized controlled trial","level":2,"score":0.31439998745918274},{"id":"https://openalex.org/C2780733359","wikidata":"https://www.wikidata.org/wiki/Q331769","display_name":"Mood","level":2,"score":0.313400000333786},{"id":"https://openalex.org/C120843803","wikidata":"https://www.wikidata.org/wiki/Q4955807","display_name":"Brain activity and meditation","level":3,"score":0.3116999864578247},{"id":"https://openalex.org/C2779226451","wikidata":"https://www.wikidata.org/wiki/Q903809","display_name":"Functional magnetic resonance imaging","level":2,"score":0.3068000078201294},{"id":"https://openalex.org/C2776317618","wikidata":"https://www.wikidata.org/wiki/Q544006","display_name":"Anxiety disorder","level":3,"score":0.30070000886917114},{"id":"https://openalex.org/C2985799443","wikidata":"https://www.wikidata.org/wiki/Q4955838","display_name":"Brain stimulation","level":3,"score":0.29499998688697815},{"id":"https://openalex.org/C2779097318","wikidata":"https://www.wikidata.org/wiki/Q2993446","display_name":"Connectomics","level":4,"score":0.28679999709129333},{"id":"https://openalex.org/C2779177272","wikidata":"https://www.wikidata.org/wiki/Q76560","display_name":"Antidepressant","level":3,"score":0.2761000096797943},{"id":"https://openalex.org/C2778402161","wikidata":"https://www.wikidata.org/wiki/Q2121931","display_name":"Anterior cingulate cortex","level":3,"score":0.2711000144481659},{"id":"https://openalex.org/C70410870","wikidata":"https://www.wikidata.org/wiki/Q199906","display_name":"Clinical psychology","level":1,"score":0.26910001039505005},{"id":"https://openalex.org/C2777342061","wikidata":"https://www.wikidata.org/wiki/Q7836891","display_name":"Treatment-resistant depression","level":4,"score":0.26669999957084656},{"id":"https://openalex.org/C58693492","wikidata":"https://www.wikidata.org/wiki/Q551875","display_name":"Neuroimaging","level":2,"score":0.26589998602867126},{"id":"https://openalex.org/C24998067","wikidata":"https://www.wikidata.org/wiki/Q4114622","display_name":"Stimulation","level":2,"score":0.26339998841285706},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.25519999861717224}],"mesh":[{"descriptor_ui":"D000087643","descriptor_name":"Dorsolateral Prefrontal Cortex","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001007","descriptor_name":"Anxiety","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D001007","descriptor_name":"Anxiety","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D003863","descriptor_name":"Depression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003865","descriptor_name":"Major Depressive Disorder","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D003865","descriptor_name":"Major Depressive Disorder","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010865","descriptor_name":"Pilot Projects","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017397","descriptor_name":"Prefrontal Cortex","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D050781","descriptor_name":"Transcranial Magnetic Stimulation","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D063132","descriptor_name":"Connectome","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1038/s41380-026-03535-1","doi":"https://doi.org/10.1038/s41380-026-03535-1","is_oa":false,"landing_page_url":"https://doi.org/10.1038/s41380-026-03535-1","pdf_url":null,"source":{"id":"https://openalex.org/S71149355","display_name":"Molecular Psychiatry","issn_l":"1359-4184","issn":["1359-4184","1476-5578"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular Psychiatry","raw_type":"journal-article"},{"id":"doi:10.21203/rs.3.rs-4791291/v1","doi":"https://doi.org/10.21203/rs.3.rs-4791291/v1","is_oa":true,"landing_page_url":"https://doi.org/10.21203/rs.3.rs-4791291/v1","pdf_url":"https://www.researchsquare.com/article/rs-4791291/latest.pdf","source":{"id":"https://openalex.org/S4306525896","display_name":"Research Square","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Research Square","raw_type":"posted-content"},{"id":"pmh:oai:pubmedcentral.nih.gov:13098680","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13098680/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13098680/pdf/nihms-2163515.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Mol Psychiatry","raw_type":"Text"},{"id":"pmid:41912790","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/41912790","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular psychiatry","raw_type":"Clinical Trial, Phase II"}],"best_oa_location":{"id":"doi:10.21203/rs.3.rs-4791291/v1","doi":"https://doi.org/10.21203/rs.3.rs-4791291/v1","is_oa":true,"landing_page_url":"https://doi.org/10.21203/rs.3.rs-4791291/v1","pdf_url":"https://www.researchsquare.com/article/rs-4791291/latest.pdf","source":{"id":"https://openalex.org/S4306525896","display_name":"Research Square","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Research Square","raw_type":"posted-content"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9922999739646912}],"study_designs":[{"display_name":"Randomized Controlled Trial","id":"https://openalex.org/study-designs/randomized-controlled-trial"},{"display_name":"Clinical Trial","id":"https://openalex.org/study-designs/clinical-trial"}],"awards":[{"id":"https://openalex.org/G1120570908","display_name":"Treating hyperexcitability in Alzheimer's disease with levetiracetam to improve brain function and cognition","funder_award_id":"R01AG060987","funder_id":"https://openalex.org/F4320337337","funder_display_name":"National Institute on Aging"},{"id":"https://openalex.org/G1244286876","display_name":"Personalized circuit-based neuromodulation targets for depression","funder_award_id":"K23MH121657","funder_id":"https://openalex.org/F4320337346","funder_display_name":"National Institute of Mental Health"},{"id":"https://openalex.org/G1630641404","display_name":null,"funder_award_id":"I01 CX002293","funder_id":"https://openalex.org/F4320306127","funder_display_name":"U.S. Department of Veterans Affairs"},{"id":"https://openalex.org/G188715211","display_name":"Targeted modulation of symptom-specific brain circuits with transcranial magnetic stimulation","funder_award_id":"R21MH126271","funder_id":"https://openalex.org/F4320337346","funder_display_name":"National Institute of Mental Health"},{"id":"https://openalex.org/G3206168920","display_name":"Reliability of Repetitive TMS-induced Modulation of Cortical Excitability","funder_award_id":"R01MH115949","funder_id":"https://openalex.org/F4320337346","funder_display_name":"National Institute of Mental Health"},{"id":"https://openalex.org/G3863163885","display_name":"Ketamine for the treatment for alcohol use disorder in the emergency department: A pilot double-blind, placebo-controlled randomized clinical trial","funder_award_id":"R21AA030372","funder_id":"https://openalex.org/F4320337330","funder_display_name":"National Institute on Alcohol Abuse and Alcoholism"},{"id":"https://openalex.org/G5032782408","display_name":null,"funder_award_id":"NIMH R21MH126271","funder_id":"https://openalex.org/F4320337346","funder_display_name":"National Institute of Mental Health"},{"id":"https://openalex.org/G6342956342","display_name":"Transdiagnostic memory, mood and motor circuits in Alzheimer's and neurodegenerative disease","funder_award_id":"R56AG069086","funder_id":"https://openalex.org/F4320337337","funder_display_name":"National Institute on Aging"},{"id":"https://openalex.org/G9000891321","display_name":"Deriving TMS Targets for Mood Valence and Mood Stabilization in Bipolar Disorder","funder_award_id":"K23MH129829","funder_id":"https://openalex.org/F4320337346","funder_display_name":"National Institute of Mental Health"},{"id":"https://openalex.org/G9000920336","display_name":"Using human brain connectivity to identify the causal neuroanatomical substrate of depression symptoms","funder_award_id":"R01MH113929","funder_id":"https://openalex.org/F4320337346","funder_display_name":"National Institute of Mental Health"}],"funders":[{"id":"https://openalex.org/F4320306127","display_name":"U.S. Department of Veterans Affairs","ror":"https://ror.org/05rsv9s98"},{"id":"https://openalex.org/F4320308349","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78"},{"id":"https://openalex.org/F4320315792","display_name":"BrainsWay","ror":"https://ror.org/03by3f970"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337330","display_name":"National Institute on Alcohol Abuse and Alcoholism","ror":"https://ror.org/02jzrsm59"},{"id":"https://openalex.org/F4320337337","display_name":"National Institute on Aging","ror":"https://ror.org/049v75w11"},{"id":"https://openalex.org/F4320337346","display_name":"National Institute of Mental Health","ror":"https://ror.org/04xeg9z08"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7143346128.pdf","grobid_xml":"https://content.openalex.org/works/W7143346128.grobid-xml"},"referenced_works_count":61,"referenced_works":["https://openalex.org/W820930954","https://openalex.org/W1550782508","https://openalex.org/W1642975344","https://openalex.org/W1869019363","https://openalex.org/W1963670337","https://openalex.org/W1964098393","https://openalex.org/W1988751658","https://openalex.org/W2004241099","https://openalex.org/W2049545999","https://openalex.org/W2060427373","https://openalex.org/W2079581133","https://openalex.org/W2095733926","https://openalex.org/W2115504852","https://openalex.org/W2141253606","https://openalex.org/W2155932495","https://openalex.org/W2162393641","https://openalex.org/W2170302543","https://openalex.org/W2171327262","https://openalex.org/W2302097048","https://openalex.org/W2407226921","https://openalex.org/W2519753596","https://openalex.org/W2560565629","https://openalex.org/W2622109244","https://openalex.org/W2767756464","https://openalex.org/W2902923903","https://openalex.org/W2911080671","https://openalex.org/W2914312460","https://openalex.org/W2935903511","https://openalex.org/W2937293138","https://openalex.org/W2951025927","https://openalex.org/W2969004444","https://openalex.org/W2982569821","https://openalex.org/W2982582461","https://openalex.org/W3011443824","https://openalex.org/W3015111688","https://openalex.org/W3021695182","https://openalex.org/W3022337098","https://openalex.org/W3048161568","https://openalex.org/W3181719595","https://openalex.org/W3208689015","https://openalex.org/W3209776446","https://openalex.org/W4200434130","https://openalex.org/W4206921358","https://openalex.org/W4210615564","https://openalex.org/W4213385012","https://openalex.org/W4224212725","https://openalex.org/W4247665917","https://openalex.org/W4295750005","https://openalex.org/W4313612970","https://openalex.org/W4317869069","https://openalex.org/W4377967799","https://openalex.org/W4385417543","https://openalex.org/W4386701448","https://openalex.org/W4388753904","https://openalex.org/W4389138867","https://openalex.org/W4389397376","https://openalex.org/W4390060863","https://openalex.org/W4396237720","https://openalex.org/W4405585988","https://openalex.org/W4408903946","https://openalex.org/W4411811135"],"related_works":["https://openalex.org/W7155618402","https://openalex.org/W2913269143","https://openalex.org/W4396221500","https://openalex.org/W7155099585","https://openalex.org/W3011443824","https://openalex.org/W4313612970","https://openalex.org/W3020253804","https://openalex.org/W3111364412","https://openalex.org/W4391059608","https://openalex.org/W4403120051"],"abstract_inverted_index":{"Abstract":[0],"Transcranial":[1],"magnetic":[2],"stimulation":[3],"(TMS)":[4],"is":[5],"effective":[6],"for":[7,140],"major":[8],"depressive":[9],"disorder":[10],"(MDD)":[11],"despite":[12],"imprecise":[13],"scalp-based":[14],"targeting.":[15],"Retrospective":[16],"analyses":[17],"suggest":[18],"that":[19],"targeting":[20,28,58,65,73,87,114,118],"one":[21],"brain":[22,31,120],"circuit":[23,32,57,64,72,86,113],"improves":[24,33],"\u201cdysphoric\u201d":[25],"symptoms,":[26],"while":[27,84],"a":[29],"different":[30,119],"\u201canxiosomatic\u201d":[34],"symptoms.":[35,128],"Here,":[36],"we":[37],"tested":[38],"this":[39],"hypothesis":[40],"prospectively.":[41],"Individuals":[42],"with":[43,55,111],"moderate-to-severe":[44,47],"MDD":[45],"and":[46,126,130,137,142],"anxiety":[48,110,125],"(n=40)":[49],"were":[50],"randomized":[51],"to":[52],"receive":[53],"TMS":[54,117],"dysphoric":[56,71],"(dorsolateral":[59],"prefrontal":[60,67],"cortex)":[61],"or":[62],"anxiosomatic":[63,85],"(dorsomedial":[66],"cortex).":[68],"As":[69],"hypothesized,":[70],"(n=16)":[74],"improved":[75,89],"BDI":[76,93],"more":[77,91],"than":[78,92],"BAI":[79,90],"(ratio":[80,94],"1.08,":[81],"IQR":[82,96],"0.69-2.02),":[83],"(n=20)":[88],"0.70,":[95],"0.01-1.01)":[97],"(Wilcoxon":[98],"rank-sum":[99],"test":[100],"p=0.0195).":[101],"This":[102],"result":[103],"was":[104],"driven":[105],"by":[106],"larger":[107],"improvements":[108],"in":[109],"-anxiosomatic":[112],"(p=0.0301).":[115],"Thus,":[116],"circuits":[121],"differentially":[122],"modulates":[123],"comorbid":[124],"depression":[127],"Symptom-":[129],"circuit-specific":[131],"trial":[132],"designs":[133],"may":[134],"improve":[135],"power":[136],"better":[138],"control":[139],"placebo":[141],"non-specific":[143],"effects.":[144]},"counts_by_year":[{"year":2026,"cited_by_count":18},{"year":2025,"cited_by_count":6},{"year":2024,"cited_by_count":1}],"updated_date":"2026-11-09T13:22:03.289127","created_date":"2026-03-31T00:00:00"}