{"id":"https://openalex.org/W7141308317","doi":"https://doi.org/10.1016/b978-0-443-34172-4.00031-8","title":"Cholestatic and uremic itch","display_name":"Cholestatic and uremic itch","publication_year":2026,"publication_date":"2026-01-01","ids":{"openalex":"https://openalex.org/W7141308317","doi":"https://doi.org/10.1016/b978-0-443-34172-4.00031-8"},"language":"en","primary_location":{"id":"doi:10.1016/b978-0-443-34172-4.00031-8","doi":"https://doi.org/10.1016/b978-0-443-34172-4.00031-8","is_oa":false,"landing_page_url":"https://doi.org/10.1016/b978-0-443-34172-4.00031-8","pdf_url":null,"source":{"id":"https://openalex.org/S4306463230","display_name":"Elsevier eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Itch Spectrum","raw_type":"book-chapter"},"volume":{"id":"https://openalex.org/W7141076522","display_name":"The Itch Spectrum"},"type":"book-chapter","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5008235419","display_name":"Miriam M. D\u00fcll","orcid":"https://orcid.org/0000-0001-6335-9158","observed_orcids":["https://orcid.org/0000-0001-6335-9158"]},"institutions":[{"id":"https://openalex.org/I181369854","display_name":"Friedrich-Alexander-Universit\u00e4t Erlangen-N\u00fcrnberg","ror":"https://ror.org/00f7hpc57","country_code":"DE","type":"education","lineage":["https://openalex.org/I181369854"]},{"id":"https://openalex.org/I4210088053","display_name":"Universit\u00e4tsklinikum Erlangen","ror":"https://ror.org/0030f2a11","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210088053"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Miriam M. D\u00fcll","raw_affiliation_strings":["Department of Medicine 1, University Hospital Erlangen and Friedrich-Alexander-University Erlangen-N\u00fcrnberg, Erlangen, Germany","Deutsches Zentrum Immuntherapie DZI, Erlangen, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine 1, University Hospital Erlangen and Friedrich-Alexander-University Erlangen-N\u00fcrnberg, Erlangen, Germany","institution_ids":["https://openalex.org/I181369854","https://openalex.org/I4210088053"]},{"raw_affiliation_string":"Deutsches Zentrum Immuntherapie DZI, Erlangen, Germany","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5081840796","display_name":"Andreas Emanuel Kremer","orcid":"https://orcid.org/0000-0002-9263-948X","observed_orcids":["https://orcid.org/0000-0002-9263-948X"]},"institutions":[{"id":"https://openalex.org/I181369854","display_name":"Friedrich-Alexander-Universit\u00e4t Erlangen-N\u00fcrnberg","ror":"https://ror.org/00f7hpc57","country_code":"DE","type":"education","lineage":["https://openalex.org/I181369854"]},{"id":"https://openalex.org/I202697423","display_name":"University of Zurich","ror":"https://ror.org/02crff812","country_code":"CH","type":"education","lineage":["https://openalex.org/I202697423"]},{"id":"https://openalex.org/I4210088053","display_name":"Universit\u00e4tsklinikum Erlangen","ror":"https://ror.org/0030f2a11","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210088053"]},{"id":"https://openalex.org/I4210100468","display_name":"University Hospital Zurich","ror":"https://ror.org/01462r250","country_code":"CH","type":"healthcare","lineage":["https://openalex.org/I4210100468"]}],"countries":["CH","DE"],"is_corresponding":false,"raw_author_name":"Andreas E. Kremer","raw_affiliation_strings":["Department of Gastroenterology and Hepatology, University Hospital Z\u00fcrich, University of Z\u00fcrich, Z\u00fcrich, Switzerland","Department of Medicine 1, University Hospital Erlangen and Friedrich-Alexander-University Erlangen-N\u00fcrnberg, Erlangen, Germany","Deutsches Zentrum Immuntherapie DZI, Erlangen, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gastroenterology and Hepatology, University Hospital Z\u00fcrich, University of Z\u00fcrich, Z\u00fcrich, Switzerland","institution_ids":["https://openalex.org/I202697423","https://openalex.org/I4210100468"]},{"raw_affiliation_string":"Department of Medicine 1, University Hospital Erlangen and Friedrich-Alexander-University Erlangen-N\u00fcrnberg, Erlangen, Germany","institution_ids":["https://openalex.org/I181369854","https://openalex.org/I4210088053"]},{"raw_affiliation_string":"Deutsches Zentrum Immuntherapie DZI, Erlangen, Germany","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.18233296,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"329","last_page":"341"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10837","display_name":"Dermatology and Skin Diseases","score":0.951200008392334,"subfield":{"id":"https://openalex.org/subfields/2708","display_name":"Dermatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10837","display_name":"Dermatology and Skin Diseases","score":0.951200008392334,"subfield":{"id":"https://openalex.org/subfields/2708","display_name":"Dermatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10291","display_name":"Dialysis and Renal Disease Management","score":0.005200000014156103,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10196","display_name":"Pain Mechanisms and Treatments","score":0.004100000020116568,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pruritus","display_name":"pruritus","score":0.9179999828338623},{"id":"https://openalex.org/keywords/chronic-kidney-disease","display_name":"chronic kidney disease","score":0.8709999918937683},{"id":"https://openalex.org/keywords/chronic-liver-disease","display_name":"chronic liver disease","score":0.972000002861023},{"id":"https://openalex.org/keywords/bile-acids","display_name":"bile acids","score":0.6380000114440918},{"id":"https://openalex.org/keywords/mrgprd","display_name":"MRGPRD","score":0.9980000257492065},{"id":"https://openalex.org/keywords/kappa-opioid-receptor","display_name":"kappa opioid receptor","score":0.8309999704360962},{"id":"https://openalex.org/keywords/difelikefalin","display_name":"difelikefalin","score":0.9940000176429749},{"id":"https://openalex.org/keywords/uremic-toxins","display_name":"uremic toxins","score":0.781000018119812},{"id":"https://openalex.org/keywords/indoxyl-sulfate","display_name":"indoxyl sulfate","score":0.9539999961853027},{"id":"https://openalex.org/keywords/allantoin","display_name":"allantoin","score":0.9629999995231628},{"id":"https://openalex.org/keywords/calcium-and-phosphorus-homeostasis","display_name":"calcium and phosphorus homeostasis","score":0.8289999961853027},{"id":"https://openalex.org/keywords/cutaneous-innervation","display_name":"skin innervation","score":0.7580000162124634},{"id":"https://openalex.org/keywords/opioid-system","display_name":"opioid system","score":0.5759999752044678},{"id":"https://openalex.org/keywords/lysophosphatidic-acid","display_name":"lysophosphatidic acid","score":0.8529999852180481},{"id":"https://openalex.org/keywords/itch-mechanisms","display_name":"itch mechanisms","score":0.5090000033378601}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7548999786376953},{"id":"https://openalex.org/C2779399885","wikidata":"https://www.wikidata.org/wiki/Q413288","display_name":"Bile acid","level":2,"score":0.5223000049591064},{"id":"https://openalex.org/C2780091579","wikidata":"https://www.wikidata.org/wiki/Q9377","display_name":"Kidney","level":2,"score":0.4634000062942505},{"id":"https://openalex.org/C2776661833","wikidata":"https://www.wikidata.org/wiki/Q2823281","display_name":"Lysophosphatidic acid","level":3,"score":0.4410000145435333},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.4025999903678894},{"id":"https://openalex.org/C2778938600","wikidata":"https://www.wikidata.org/wiki/Q389934","display_name":"Agonist","level":3,"score":0.334199994802475},{"id":"https://openalex.org/C2778653478","wikidata":"https://www.wikidata.org/wiki/Q1054718","display_name":"Kidney disease","level":2,"score":0.33000001311302185},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.30809998512268066},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.30480000376701355},{"id":"https://openalex.org/C2777214474","wikidata":"https://www.wikidata.org/wiki/Q147778","display_name":"Cirrhosis","level":2,"score":0.29330000281333923},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.26089999079704285}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/b978-0-443-34172-4.00031-8","doi":"https://doi.org/10.1016/b978-0-443-34172-4.00031-8","is_oa":false,"landing_page_url":"https://doi.org/10.1016/b978-0-443-34172-4.00031-8","pdf_url":null,"source":{"id":"https://openalex.org/S4306463230","display_name":"Elsevier eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Itch Spectrum","raw_type":"book-chapter"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9537000060081482,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":113,"referenced_works":["https://openalex.org/W36003463","https://openalex.org/W1545913426","https://openalex.org/W1557396643","https://openalex.org/W1970263282","https://openalex.org/W1971837450","https://openalex.org/W1975809640","https://openalex.org/W1988408110","https://openalex.org/W1989709559","https://openalex.org/W1995517056","https://openalex.org/W2004435536","https://openalex.org/W2010189325","https://openalex.org/W2013241580","https://openalex.org/W2014943569","https://openalex.org/W2021475268","https://openalex.org/W2023696004","https://openalex.org/W2023752243","https://openalex.org/W2032062642","https://openalex.org/W2039947236","https://openalex.org/W2040926476","https://openalex.org/W2043916843","https://openalex.org/W2045223517","https://openalex.org/W2062261237","https://openalex.org/W2065909481","https://openalex.org/W2068043591","https://openalex.org/W2072982915","https://openalex.org/W2075644994","https://openalex.org/W2079146831","https://openalex.org/W2089109720","https://openalex.org/W2093292173","https://openalex.org/W2105176852","https://openalex.org/W2108087274","https://openalex.org/W2111533254","https://openalex.org/W2115590061","https://openalex.org/W2117798291","https://openalex.org/W2118866905","https://openalex.org/W2119965510","https://openalex.org/W2124382028","https://openalex.org/W2130281254","https://openalex.org/W2136860906","https://openalex.org/W2139861148","https://openalex.org/W2140123841","https://openalex.org/W2144641720","https://openalex.org/W2146764867","https://openalex.org/W2147889176","https://openalex.org/W2154913409","https://openalex.org/W2159924115","https://openalex.org/W2160188055","https://openalex.org/W2168681401","https://openalex.org/W2171685278","https://openalex.org/W2213313540","https://openalex.org/W2236135063","https://openalex.org/W2238330273","https://openalex.org/W2346140086","https://openalex.org/W2348308547","https://openalex.org/W2402117629","https://openalex.org/W2414590316","https://openalex.org/W2500163800","https://openalex.org/W2518389324","https://openalex.org/W2586480777","https://openalex.org/W2592427646","https://openalex.org/W2726471463","https://openalex.org/W2810661595","https://openalex.org/W2903575659","https://openalex.org/W2909951700","https://openalex.org/W2910487479","https://openalex.org/W2912717193","https://openalex.org/W2913532420","https://openalex.org/W2914445924","https://openalex.org/W2936325970","https://openalex.org/W2944749860","https://openalex.org/W2966236039","https://openalex.org/W2966834148","https://openalex.org/W2972641132","https://openalex.org/W2985069633","https://openalex.org/W2988468898","https://openalex.org/W2993083975","https://openalex.org/W2999094105","https://openalex.org/W3011716780","https://openalex.org/W3017176778","https://openalex.org/W3047643652","https://openalex.org/W3098760744","https://openalex.org/W3134250283","https://openalex.org/W3149206400","https://openalex.org/W3154098947","https://openalex.org/W3175402370","https://openalex.org/W3175994617","https://openalex.org/W3176655397","https://openalex.org/W3198355413","https://openalex.org/W3208565007","https://openalex.org/W3214988211","https://openalex.org/W3215716637","https://openalex.org/W4220828378","https://openalex.org/W4223605727","https://openalex.org/W4253946839","https://openalex.org/W4281647171","https://openalex.org/W4282926324","https://openalex.org/W4283763388","https://openalex.org/W4283813391","https://openalex.org/W4293496222","https://openalex.org/W4306642647","https://openalex.org/W4306726715","https://openalex.org/W4307771971","https://openalex.org/W4323348337","https://openalex.org/W4379207386","https://openalex.org/W4387965403","https://openalex.org/W4390016082","https://openalex.org/W4392015136","https://openalex.org/W4392164679","https://openalex.org/W4396675132","https://openalex.org/W4399459662","https://openalex.org/W4400937723","https://openalex.org/W4407722625","https://openalex.org/W4408673346"],"related_works":[],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-10T09:11:00.788812","created_date":"2026-03-28T00:00:00"}