{"id":"https://openalex.org/W7140890262","doi":"https://doi.org/10.1227/neu.0000000000003964_1075","title":"1075 Electrocorticography Reveals Movement-Associated Cortical Beta Rhythm Modulation in Transcranial Direct Current Stimulation for Parkinson's Disease","display_name":"1075 Electrocorticography Reveals Movement-Associated Cortical Beta Rhythm Modulation in Transcranial Direct Current Stimulation for Parkinson's Disease","publication_year":2026,"publication_date":"2026-03-26","ids":{"openalex":"https://openalex.org/W7140890262","doi":"https://doi.org/10.1227/neu.0000000000003964_1075"},"language":"en","primary_location":{"id":"doi:10.1227/neu.0000000000003964_1075","doi":"https://doi.org/10.1227/neu.0000000000003964_1075","is_oa":false,"landing_page_url":"https://doi.org/10.1227/neu.0000000000003964_1075","pdf_url":null,"source":{"id":"https://openalex.org/S111727011","display_name":"Neurosurgery","issn_l":"0148-396X","issn":["0148-396X","1081-1281","1524-4040"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neurosurgery","raw_type":"journal-article"},"volume":null,"type":"conference-abstract","is_traditional":false,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5020872700","display_name":"Rishi Suresh","orcid":"https://orcid.org/0000-0001-6507-261X","observed_orcids":["https://orcid.org/0000-0001-6507-261X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Rishi Suresh","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082974853","display_name":"Nathan Christopher Rowland","orcid":"https://orcid.org/0000-0002-6414-931X","observed_orcids":["https://orcid.org/0000-0002-6414-931X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Nathan C. Rowland","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5130683815","display_name":"Terry Roddey","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Terry Roddey","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5116316083","display_name":"Tracy A. Aggrey-Ansong","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Tracy Aggrey-Ansong","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"72","issue":"Supplement_1","first_page":"198","last_page":"198"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10614","display_name":"Transcranial Magnetic Stimulation Studies","score":0.8949999809265137,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10614","display_name":"Transcranial Magnetic Stimulation Studies","score":0.8949999809265137,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10919","display_name":"Deep Brain Stimulation and Movement Disorders","score":0.10350000113248825,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11123","display_name":"Obsessive-Compulsive Spectrum Disorders","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/3203","display_name":"Clinical Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/parkinson-s-disease","display_name":"Parkinson's disease","score":0.8669999837875366},{"id":"https://openalex.org/keywords/transcranial-direct-current-stimulation","display_name":"transcranial direct current stimulation","score":0.9909999966621399},{"id":"https://openalex.org/keywords/electrocorticography","display_name":"electrocorticography","score":0.9229999780654907},{"id":"https://openalex.org/keywords/tremor-suppression","display_name":"tremor suppression","score":0.9229999780654907},{"id":"https://openalex.org/keywords/deep-brain-stimulation","display_name":"deep brain stimulation","score":0.8510000109672546},{"id":"https://openalex.org/keywords/primary-motor-cortex","display_name":"primary motor cortex","score":0.7680000066757202},{"id":"https://openalex.org/keywords/essential-tremor","display_name":"essential tremor","score":0.5979999899864197},{"id":"https://openalex.org/keywords/non-invasive-brain-stimulation","display_name":"non-invasive brain stimulation","score":0.6620000004768372},{"id":"https://openalex.org/keywords/mechanism-of-action","display_name":"mechanism of action","score":0.6470000147819519},{"id":"https://openalex.org/keywords/power-spectral-density","display_name":"power spectral density","score":0.5979999899864197},{"id":"https://openalex.org/keywords/theta-activity","display_name":"theta activity","score":0.41499999165534973}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9275000095367432},{"id":"https://openalex.org/C2780117969","wikidata":"https://www.wikidata.org/wiki/Q3587624","display_name":"Electrocorticography","level":3,"score":0.7337999939918518},{"id":"https://openalex.org/C2777803708","wikidata":"https://www.wikidata.org/wiki/Q603398","display_name":"Transcranial direct-current stimulation","level":3,"score":0.633899986743927},{"id":"https://openalex.org/C2776174256","wikidata":"https://www.wikidata.org/wiki/Q830842","display_name":"BETA (programming language)","level":2,"score":0.6330999732017517},{"id":"https://openalex.org/C24998067","wikidata":"https://www.wikidata.org/wiki/Q4114622","display_name":"Stimulation","level":2,"score":0.5523999929428101},{"id":"https://openalex.org/C123079801","wikidata":"https://www.wikidata.org/wiki/Q750240","display_name":"Modulation (music)","level":2,"score":0.5242000222206116},{"id":"https://openalex.org/C135343436","wikidata":"https://www.wikidata.org/wiki/Q170406","display_name":"Rhythm","level":2,"score":0.5073000192642212},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.5001999735832214},{"id":"https://openalex.org/C2776620479","wikidata":"https://www.wikidata.org/wiki/Q159241","display_name":"Direct current","level":3,"score":0.4456999897956848},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.4081000089645386},{"id":"https://openalex.org/C90987802","wikidata":"https://www.wikidata.org/wiki/Q1138877","display_name":"Transcranial alternating current stimulation","level":4,"score":0.3889999985694885},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3880999982357025},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.34630000591278076},{"id":"https://openalex.org/C148043351","wikidata":"https://www.wikidata.org/wiki/Q4456944","display_name":"Current (fluid)","level":2,"score":0.34119999408721924},{"id":"https://openalex.org/C2910144760","wikidata":"https://www.wikidata.org/wiki/Q831014","display_name":"Beta Rhythm","level":3,"score":0.3312999904155731},{"id":"https://openalex.org/C522805319","wikidata":"https://www.wikidata.org/wiki/Q179965","display_name":"Electroencephalography","level":2,"score":0.28200000524520874},{"id":"https://openalex.org/C2780375056","wikidata":"https://www.wikidata.org/wiki/Q905905","display_name":"Neuromodulation","level":3,"score":0.25690001249313354},{"id":"https://openalex.org/C2985799443","wikidata":"https://www.wikidata.org/wiki/Q4955838","display_name":"Brain stimulation","level":3,"score":0.2556999921798706}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1227/neu.0000000000003964_1075","doi":"https://doi.org/10.1227/neu.0000000000003964_1075","is_oa":false,"landing_page_url":"https://doi.org/10.1227/neu.0000000000003964_1075","pdf_url":null,"source":{"id":"https://openalex.org/S111727011","display_name":"Neurosurgery","issn_l":"0148-396X","issn":["0148-396X","1081-1281","1524-4040"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neurosurgery","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.98580002784729,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2697636610","https://openalex.org/W3207742320","https://openalex.org/W4403353272","https://openalex.org/W2007021711","https://openalex.org/W2756021835","https://openalex.org/W4391484153","https://openalex.org/W2101436214","https://openalex.org/W2914049140","https://openalex.org/W4395021117","https://openalex.org/W2578036900"],"abstract_inverted_index":{"INTRODUCTION:":[0],"Deep":[1],"brain":[2,383],"stimulation":[3,46,119,201,462],"(DBS)":[4],"is":[5,54],"currently":[6],"the":[7,109,121,127,139,143,325,355,381,430],"gold-standard":[8],"procedure":[9],"for":[10,22,105,206,253,444],"medically":[11],"refractory":[12],"Parkinson's":[13],"disease":[14,198],"(PD).":[15],"Many":[16],"PD":[17,98,264,299,339,382],"patients":[18,102,296,300],"are":[19],"not":[20,352,370,386],"candidates":[21],"neurosurgical":[23],"intervention":[24],"and":[25,99,149,170,175,195,200,222,250,265,283,322,334,347,448,451],"may":[26,60,394,452],"also":[27,362],"be":[28,61],"at":[29,155,173,219,392],"risk":[30],"of":[31,67,70,433],"complications":[32],"such":[33,41],"as":[34,42],"neurocognitive":[35],"decline":[36],"or":[37,132,271],"hemorrhage.":[38],"Non-invasive":[39],"alternatives":[40],"transcranial":[43],"direct":[44],"current":[45],"(tDCS)":[47],"have":[48,404],"shown":[49,406],"promise,":[50],"but":[51,274,297,368],"widespread":[52],"use":[53],"limited":[55],"by":[56],"inconsistent":[57],"results.":[58,78],"This":[59,438],"due":[62],"to":[63,76,93,117,120,126,138,161,178,224,241,269,302,333,380,407,419,422,463],"an":[64,365],"incomplete":[65],"understanding":[66],"its":[68],"mechanism":[69],"action":[71],"which":[72,341,403,435,458],"prevents":[73],"tailoring":[74],"therapy":[75],"improve":[77],"We":[79],"hypothesized":[80],"that":[81,319,384],"tDCS":[82,116,289,321,376,445],"targeted":[83],"cortical":[84,424,455],"beta":[85,91,270,329,349,425],"rhythms":[86],"correlated":[87,342],"with":[88,238,267,314,343,372,396,409],"basal":[89],"ganglia":[90],"entrainment":[92],"suppress":[94],"tremor.":[95,437,465],"METHODS:":[96],"6":[97],"8":[100],"ET":[101,266,295,366],"were":[103,152,228],"recruited":[104],"this":[106,348],"study.":[107],"During":[108],"DBS":[110,128,323],"operation,":[111],"we":[112,259],"used":[113],"high-density":[114],"anodal":[115],"apply":[118,461],"primary":[122],"motor":[123,140],"cortex":[124,141],"ipsilateral":[125],"craniotomy":[129],"site.":[130],"Six":[131],"eight-channel":[133],"ECOG":[134,225],"electrode":[135],"was":[136,159,185,214,351,361],"advanced":[137],"through":[142],"cranial":[144],"defect":[145],"(below).":[146],"Baseline,":[147],"intra-stimulation,":[148],"post-stimulation":[150,326],"recordings":[151],"obtained":[153,215],"sampled":[154],"3":[156,188],"kHz.":[157],"Signal":[158],"downsampled":[160],"1":[162],"kHz,":[163],"common":[164],"average":[165],"referenced":[166],"over":[167,187],"all":[168],"channels,":[169],"notch":[171],"filtered":[172],"60":[174],"120":[176],"Hz":[177,221],"remove":[179],"powerline":[180],"noise.":[181],"Power":[182],"spectral":[183,277,292],"density":[184],"calculated":[186],"five-second":[189],"epochs":[190],"per":[191,193],"channel":[192],"patient":[194,340],"compared":[196],"between":[197,263],"groups":[199],"states":[202],"using":[203,230,235],"Welch's":[204],"method":[205],"discrete":[207],"Fourier":[208,232],"transform":[209,233],"(DFT).":[210],"VR":[211,217,315],"kinematic":[212,316,345],"data":[213,317],"from":[216],"controllers":[218],"75":[220],"synced":[223],"data.":[226],"Spectrograms":[227,310],"produced":[229,311],"short-time":[231],"(STFT)":[234],"Hamming":[236],"window":[237],"90%":[239],"overlap":[240],"analyze":[242],"movement-related":[243],"changes.":[244],"Statistical":[245],"analysis":[246],"involved":[247],"two-way":[248],"ANOVA":[249],"Bonferroni":[251],"correction":[252],"multiple":[254],"comparisons.":[255],"RESULTS:":[256],"At":[257],"baseline,":[258],"observed":[260,275],"no":[261,291],"differences":[262],"respect":[268],"alpha":[272],"PSD,":[273],"increased":[276],"power":[278,401],"in":[279,294,298,306,312,324,337,354,364,388,411],"delta,":[280],"theta,":[281],"gamma":[282,285],"high":[284],"bands.":[286],"2":[287],"mA":[288],"induced":[290],"changes":[293,379,391],"led":[301],"a":[303,440,454],"significant":[304],"increase":[305],"theta":[307,400],"PSD":[308],"only.":[309],"correlation":[313],"revealed":[318],"both":[320],"state":[327],"prolonged":[328,363],"burst":[330,359,427],"activity":[331,350,428],"prior":[332],"during":[335,414,429],"movement":[336,415,434],"one":[338],"suppressed":[344],"tremor,":[346],"present":[353],"pre-stimulation":[356],"state.":[357],"Beta":[358],"behavior":[360],"patient,":[367],"did":[369],"correlate":[371,395,408],"tremor":[373,397,410],"suppression.":[374],"CONCLUSIONS:":[375],"exerts":[377],"broad-spectrum":[378],"do":[385],"occur":[387],"ET.":[389],"These":[390],"rest":[393],"suppression,":[398],"especially":[399],"changes,":[402],"been":[405],"PD.":[412],"However,":[413],"initiation,":[416],"tDCS,":[417],"similarly":[418],"DBS,":[420],"appears":[421],"induce":[423],"rhythm":[426],"preparatory":[431],"phase":[432],"suppresses":[436],"represents":[439],"potential":[441],"target":[442],"biomarker":[443],"treatment":[446],"optimization":[447],"response":[449],"monitoring":[450],"portend":[453],"brain-computer":[456],"interface":[457],"can":[459],"adaptively":[460],"treat":[464]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2026-03-27T00:00:00"}