{"id":"https://openalex.org/W7140829974","doi":"https://doi.org/10.1093/gbe/evag070","title":"De Novo Chromosome-Level Assembly of the Endangered Pilocarpus Microphyllus Highlights Genomic Resources for Conservation and Sustainable Pilocarpine Extraction","display_name":"De Novo Chromosome-Level Assembly of the Endangered Pilocarpus Microphyllus Highlights Genomic Resources for Conservation and Sustainable Pilocarpine Extraction","publication_year":2026,"publication_date":"2026-03-01","ids":{"openalex":"https://openalex.org/W7140829974","doi":"https://doi.org/10.1093/gbe/evag070","pmid":"https://pubmed.ncbi.nlm.nih.gov/41885800","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/13034126"},"language":"en","primary_location":{"id":"doi:10.1093/gbe/evag070","doi":"https://doi.org/10.1093/gbe/evag070","is_oa":true,"landing_page_url":"https://doi.org/10.1093/gbe/evag070","pdf_url":null,"source":{"id":"https://openalex.org/S10195028","display_name":"Genome Biology and Evolution","issn_l":"1759-6653","issn":["1759-6653"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-d","doyens","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Genome Biology and Evolution","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1093/gbe/evag070","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5055770820","display_name":"Mariane B. Sobreiro","orcid":"https://orcid.org/0000-0002-9459-1459","observed_orcids":["https://orcid.org/0000-0002-9459-1459"]},"institutions":[{"id":"https://openalex.org/I4210161302","display_name":"Vale Technological Institute","ror":"https://ror.org/05wnasr61","country_code":"BR","type":"education","lineage":["https://openalex.org/I4210161302"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Mariane Brom Sobreiro","raw_affiliation_strings":["Environmental Genomics, Instituto Tecnolo\u0301gico Vale , Bele\u0301m, PA ,"],"raw_orcid":"https://orcid.org/0000-0002-9459-1459","affiliations":[{"raw_affiliation_string":"Environmental Genomics, Instituto Tecnolo\u0301gico Vale , Bele\u0301m, PA ,","institution_ids":["https://openalex.org/I4210161302"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5130711735","display_name":"Leandro Magalh\u00e3es","orcid":"https://orcid.org/0000-0002-2399-7769","observed_orcids":["https://orcid.org/0000-0002-2399-7769"]},"institutions":[{"id":"https://openalex.org/I4210161302","display_name":"Vale Technological Institute","ror":"https://ror.org/05wnasr61","country_code":"BR","type":"education","lineage":["https://openalex.org/I4210161302"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Leandro Magalh\u00e3es","raw_affiliation_strings":["Environmental Genomics, Instituto Tecnolo\u0301gico Vale , Bele\u0301m, PA ,"],"raw_orcid":"https://orcid.org/0000-0002-2399-7769","affiliations":[{"raw_affiliation_string":"Environmental Genomics, Instituto Tecnolo\u0301gico Vale , Bele\u0301m, PA ,","institution_ids":["https://openalex.org/I4210161302"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011648104","display_name":"Leandro Ara\u00fajo Arg\u00f4lo","orcid":"https://orcid.org/0000-0001-9049-7505","observed_orcids":["https://orcid.org/0000-0001-9049-7505"]},"institutions":[{"id":"https://openalex.org/I4210161302","display_name":"Vale Technological Institute","ror":"https://ror.org/05wnasr61","country_code":"BR","type":"education","lineage":["https://openalex.org/I4210161302"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Leandro Ara\u00fajo Argolo","raw_affiliation_strings":["Environmental Genomics, Instituto Tecnolo\u0301gico Vale , Bele\u0301m, PA ,"],"raw_orcid":"https://orcid.org/0000-0001-9049-7505","affiliations":[{"raw_affiliation_string":"Environmental Genomics, Instituto Tecnolo\u0301gico Vale , Bele\u0301m, PA ,","institution_ids":["https://openalex.org/I4210161302"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022842489","display_name":"Camila Leit\u00e3o Nacif","orcid":"https://orcid.org/0000-0001-7016-7242","observed_orcids":["https://orcid.org/0000-0001-7016-7242"]},"institutions":[{"id":"https://openalex.org/I4210161302","display_name":"Vale Technological Institute","ror":"https://ror.org/05wnasr61","country_code":"BR","type":"education","lineage":["https://openalex.org/I4210161302"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Camila Leit\u00e3o Nacif","raw_affiliation_strings":["Environmental Genomics, Instituto Tecnolo\u0301gico Vale , Bele\u0301m, PA ,"],"raw_orcid":"https://orcid.org/0000-0001-7016-7242","affiliations":[{"raw_affiliation_string":"Environmental Genomics, Instituto Tecnolo\u0301gico Vale , Bele\u0301m, PA ,","institution_ids":["https://openalex.org/I4210161302"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047136190","display_name":"Carlos Eduardo de Ara\u00fajo Batista","orcid":"https://orcid.org/0000-0003-4691-4142","observed_orcids":["https://orcid.org/0000-0003-4691-4142"]},"institutions":[{"id":"https://openalex.org/I4210161302","display_name":"Vale Technological Institute","ror":"https://ror.org/05wnasr61","country_code":"BR","type":"education","lineage":["https://openalex.org/I4210161302"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Carlos Eduardo de Ara\u00fajo Batista","raw_affiliation_strings":["Environmental Genomics, Instituto Tecnolo\u0301gico Vale , Bele\u0301m, PA ,"],"raw_orcid":"https://orcid.org/0000-0003-4691-4142","affiliations":[{"raw_affiliation_string":"Environmental Genomics, Instituto Tecnolo\u0301gico Vale , Bele\u0301m, PA ,","institution_ids":["https://openalex.org/I4210161302"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5118140575","display_name":"D\u00e9bora de Morais Cordeiro","orcid":"https://orcid.org/0009-0006-0520-7125","observed_orcids":["https://orcid.org/0009-0006-0520-7125"]},"institutions":[{"id":"https://openalex.org/I4210161302","display_name":"Vale Technological Institute","ror":"https://ror.org/05wnasr61","country_code":"BR","type":"education","lineage":["https://openalex.org/I4210161302"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"D\u00e9bora de Morais Cordeiro","raw_affiliation_strings":["Environmental Genomics, Instituto Tecnolo\u0301gico Vale , Bele\u0301m, PA ,"],"raw_orcid":"https://orcid.org/0009-0006-0520-7125","affiliations":[{"raw_affiliation_string":"Environmental Genomics, Instituto Tecnolo\u0301gico Vale , Bele\u0301m, PA ,","institution_ids":["https://openalex.org/I4210161302"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072711119","display_name":"Renato R. M. Oliveira","orcid":"https://orcid.org/0000-0002-0111-8209","observed_orcids":["https://orcid.org/0000-0002-0111-8209"]},"institutions":[{"id":"https://openalex.org/I4210161302","display_name":"Vale Technological Institute","ror":"https://ror.org/05wnasr61","country_code":"BR","type":"education","lineage":["https://openalex.org/I4210161302"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Renato Renison Moreira-Oliveira","raw_affiliation_strings":["Environmental Genomics, Instituto Tecnolo\u0301gico Vale , Bele\u0301m, PA ,"],"raw_orcid":"https://orcid.org/0000-0002-0111-8209","affiliations":[{"raw_affiliation_string":"Environmental Genomics, Instituto Tecnolo\u0301gico Vale , Bele\u0301m, PA ,","institution_ids":["https://openalex.org/I4210161302"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5126881289","display_name":"Guilherme Oliveira","orcid":"https://orcid.org/0000-0003-0054-3438","observed_orcids":["https://orcid.org/0000-0003-0054-3438"]},"institutions":[{"id":"https://openalex.org/I4210161302","display_name":"Vale Technological Institute","ror":"https://ror.org/05wnasr61","country_code":"BR","type":"education","lineage":["https://openalex.org/I4210161302"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Guilherme Oliveira","raw_affiliation_strings":["Environmental Genomics, Instituto Tecnolo\u0301gico Vale , Bele\u0301m, PA ,"],"raw_orcid":"https://orcid.org/0000-0003-0054-3438","affiliations":[{"raw_affiliation_string":"Environmental Genomics, Instituto Tecnolo\u0301gico Vale , Bele\u0301m, PA ,","institution_ids":["https://openalex.org/I4210161302"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052609445","display_name":"Alexandre Luis Padovan Aleixo","orcid":"https://orcid.org/0000-0002-7816-9725","observed_orcids":["https://orcid.org/0000-0002-7816-9725"]},"institutions":[{"id":"https://openalex.org/I4210161302","display_name":"Vale Technological Institute","ror":"https://ror.org/05wnasr61","country_code":"BR","type":"education","lineage":["https://openalex.org/I4210161302"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Alexandre Aleixo","raw_affiliation_strings":["Environmental Genomics, Instituto Tecnolo\u0301gico Vale , Bele\u0301m, PA ,"],"raw_orcid":"https://orcid.org/0000-0002-7816-9725","affiliations":[{"raw_affiliation_string":"Environmental Genomics, Instituto Tecnolo\u0301gico Vale , Bele\u0301m, PA ,","institution_ids":["https://openalex.org/I4210161302"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5125750783","display_name":"Carolina da Silva Carvalho","orcid":"https://orcid.org/0000-0002-0063-2185","observed_orcids":["https://orcid.org/0000-0002-0063-2185"]},"institutions":[{"id":"https://openalex.org/I4210161302","display_name":"Vale Technological Institute","ror":"https://ror.org/05wnasr61","country_code":"BR","type":"education","lineage":["https://openalex.org/I4210161302"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Carolina da Silva Carvalho","raw_affiliation_strings":["Environmental Genomics, Instituto Tecnolo\u0301gico Vale , Bele\u0301m, PA ,"],"raw_orcid":"https://orcid.org/0000-0002-0063-2185","affiliations":[{"raw_affiliation_string":"Environmental Genomics, Instituto Tecnolo\u0301gico Vale , Bele\u0301m, PA ,","institution_ids":["https://openalex.org/I4210161302"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079778844","display_name":"Cec\u00edlio Fr\u00f3is Caldeira","orcid":"https://orcid.org/0000-0003-4762-3515","observed_orcids":["https://orcid.org/0000-0003-4762-3515"]},"institutions":[{"id":"https://openalex.org/I4210161302","display_name":"Vale Technological Institute","ror":"https://ror.org/05wnasr61","country_code":"BR","type":"education","lineage":["https://openalex.org/I4210161302"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Cec\u00edlio Frois Caldeira","raw_affiliation_strings":["Environmental Genomics, Instituto Tecnolo\u0301gico Vale , Bele\u0301m, PA ,"],"raw_orcid":"https://orcid.org/0000-0003-4762-3515","affiliations":[{"raw_affiliation_string":"Environmental Genomics, Instituto Tecnolo\u0301gico Vale , Bele\u0301m, PA ,","institution_ids":["https://openalex.org/I4210161302"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034201726","display_name":"Sibelle Torres Vila\u00e7a","orcid":"https://orcid.org/0000-0002-6887-4703","observed_orcids":["https://orcid.org/0000-0002-6887-4703"]},"institutions":[{"id":"https://openalex.org/I4210161302","display_name":"Vale Technological Institute","ror":"https://ror.org/05wnasr61","country_code":"BR","type":"education","lineage":["https://openalex.org/I4210161302"]}],"countries":["BR"],"is_corresponding":true,"raw_author_name":"Sibelle Torres Vila\u00e7a","raw_affiliation_strings":["Environmental Genomics, Instituto Tecnolo\u0301gico Vale , Bele\u0301m, PA ,"],"raw_orcid":"https://orcid.org/0000-0002-6887-4703","affiliations":[{"raw_affiliation_string":"Environmental Genomics, Instituto Tecnolo\u0301gico Vale , Bele\u0301m, PA ,","institution_ids":["https://openalex.org/I4210161302"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5082398078","display_name":"Amanda Ferreira Vidal","orcid":"https://orcid.org/0000-0003-4180-9925","observed_orcids":["https://orcid.org/0000-0003-4180-9925"]},"institutions":[{"id":"https://openalex.org/I4210161302","display_name":"Vale Technological Institute","ror":"https://ror.org/05wnasr61","country_code":"BR","type":"education","lineage":["https://openalex.org/I4210161302"]}],"countries":["BR"],"is_corresponding":true,"raw_author_name":"Amanda F Vidal","raw_affiliation_strings":["Environmental Genomics, Instituto Tecnolo\u0301gico Vale , Bele\u0301m, PA ,"],"raw_orcid":"https://orcid.org/0000-0003-4180-9925","affiliations":[{"raw_affiliation_string":"Environmental Genomics, Instituto Tecnolo\u0301gico Vale , Bele\u0301m, PA ,","institution_ids":["https://openalex.org/I4210161302"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5034201726","https://openalex.org/A5082398078"],"corresponding_institution_ids":["https://openalex.org/I4210161302"],"apc_list":{"value":2850,"currency":"USD","value_usd":2850},"apc_paid":{"value":2850,"currency":"USD","value_usd":2850},"fwci":2.3338,"has_fulltext":true,"cited_by_count":1,"citation_normalized_percentile":{"value":0.84609001,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":91,"max":95},"biblio":{"volume":"18","issue":"3","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10434","display_name":"Chromosomal and Genetic Variations","score":0.7026000022888184,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10434","display_name":"Chromosomal and Genetic Variations","score":0.7026000022888184,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10015","display_name":"Genomics and Phylogenetic Studies","score":0.2809999883174896,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10385","display_name":"Plant Diversity and Evolution","score":0.003000000026077032,"subfield":{"id":"https://openalex.org/subfields/1105","display_name":"Ecology, Evolution, Behavior and Systematics"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pilocarpus-microphyllus","display_name":"Pilocarpus microphyllus","score":1.0},{"id":"https://openalex.org/keywords/jaborandi","display_name":"jaborandi","score":0.9120000004768372},{"id":"https://openalex.org/keywords/pilocarpine","display_name":"pilocarpine","score":0.8889999985694885},{"id":"https://openalex.org/keywords/chromosome-level-genome-assembly","display_name":"chromosome-level genome assembly","score":0.9359999895095825},{"id":"https://openalex.org/keywords/haplotype-phasing","display_name":"haplotype phasing","score":0.8700000047683716},{"id":"https://openalex.org/keywords/genome-annotation","display_name":"genome annotation","score":0.6480000019073486},{"id":"https://openalex.org/keywords/repetitive-dna","display_name":"repetitive DNA","score":0.6000000238418579},{"id":"https://openalex.org/keywords/plant-conservation","display_name":"plant conservation","score":0.5960000157356262},{"id":"https://openalex.org/keywords/threatened-plant-species","display_name":"threatened plant species","score":0.7519999742507935},{"id":"https://openalex.org/keywords/alkaloid-biosynthesis","display_name":"alkaloid biosynthesis","score":0.6060000061988831}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8544999957084656},{"id":"https://openalex.org/C151810110","wikidata":"https://www.wikidata.org/wiki/Q7307074","display_name":"RefSeq","level":4,"score":0.734499990940094},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.7343999743461609},{"id":"https://openalex.org/C179345059","wikidata":"https://www.wikidata.org/wiki/Q11394","display_name":"Endangered species","level":3,"score":0.7294999957084656},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.5393999814987183},{"id":"https://openalex.org/C78458016","wikidata":"https://www.wikidata.org/wiki/Q840400","display_name":"Evolutionary biology","level":1,"score":0.4269999861717224},{"id":"https://openalex.org/C18949551","wikidata":"https://www.wikidata.org/wiki/Q740578","display_name":"Sequence assembly","level":5,"score":0.4187999963760376},{"id":"https://openalex.org/C197077220","wikidata":"https://www.wikidata.org/wiki/Q720988","display_name":"Human genome","level":4,"score":0.383899986743927},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.3792000114917755},{"id":"https://openalex.org/C189206191","wikidata":"https://www.wikidata.org/wiki/Q222046","display_name":"Genomics","level":4,"score":0.3343999981880188},{"id":"https://openalex.org/C150903083","wikidata":"https://www.wikidata.org/wiki/Q7108","display_name":"Biotechnology","level":1,"score":0.3089999854564667},{"id":"https://openalex.org/C192953774","wikidata":"https://www.wikidata.org/wiki/Q7307127","display_name":"Reference genome","level":4,"score":0.29899999499320984},{"id":"https://openalex.org/C89566754","wikidata":"https://www.wikidata.org/wiki/Q2273828","display_name":"Genome project","level":4,"score":0.2825999855995178},{"id":"https://openalex.org/C15151743","wikidata":"https://www.wikidata.org/wiki/Q903778","display_name":"Metagenomics","level":3,"score":0.27649998664855957},{"id":"https://openalex.org/C189592816","wikidata":"https://www.wikidata.org/wiki/Q427626","display_name":"Taxonomic rank","level":3,"score":0.26910001039505005},{"id":"https://openalex.org/C46111723","wikidata":"https://www.wikidata.org/wiki/Q471857","display_name":"Proteomics","level":3,"score":0.2612000107765198},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.2535000145435333},{"id":"https://openalex.org/C22322919","wikidata":"https://www.wikidata.org/wiki/Q5533501","display_name":"Genomic organization","level":4,"score":0.2513999938964844}],"mesh":[{"descriptor_ui":"D010862","descriptor_name":"Pilocarpine","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":true},{"descriptor_ui":"D018745","descriptor_name":"Genome, Plant","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D032103","descriptor_name":"Pilocarpus","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D032103","descriptor_name":"Pilocarpus","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D032461","descriptor_name":"Chromosomes, Plant","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D056727","descriptor_name":"Endangered Species","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1093/gbe/evag070","doi":"https://doi.org/10.1093/gbe/evag070","is_oa":true,"landing_page_url":"https://doi.org/10.1093/gbe/evag070","pdf_url":null,"source":{"id":"https://openalex.org/S10195028","display_name":"Genome Biology and Evolution","issn_l":"1759-6653","issn":["1759-6653"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-d","doyens","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Genome Biology and Evolution","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:13034126","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13034126/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13034126/pdf/evag070.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Genome Biol Evol","raw_type":"Text"},{"id":"pmid:41885800","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/41885800","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Genome biology and evolution","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1093/gbe/evag070","doi":"https://doi.org/10.1093/gbe/evag070","is_oa":true,"landing_page_url":"https://doi.org/10.1093/gbe/evag070","pdf_url":null,"source":{"id":"https://openalex.org/S10195028","display_name":"Genome Biology and Evolution","issn_l":"1759-6653","issn":["1759-6653"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-d","doyens","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Genome Biology and Evolution","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7140829974.pdf","grobid_xml":"https://content.openalex.org/works/W7140829974.grobid-xml"},"referenced_works_count":43,"referenced_works":["https://openalex.org/W166124571","https://openalex.org/W1986998800","https://openalex.org/W1996228949","https://openalex.org/W2036897871","https://openalex.org/W2074620061","https://openalex.org/W2091705028","https://openalex.org/W2140247198","https://openalex.org/W2612261225","https://openalex.org/W2728408188","https://openalex.org/W2755358631","https://openalex.org/W2792820199","https://openalex.org/W2900629010","https://openalex.org/W2946021510","https://openalex.org/W2971559821","https://openalex.org/W3012094285","https://openalex.org/W3014502522","https://openalex.org/W3047598142","https://openalex.org/W3085758516","https://openalex.org/W3119908887","https://openalex.org/W3131055609","https://openalex.org/W3203343200","https://openalex.org/W3213504861","https://openalex.org/W4200564640","https://openalex.org/W4207054657","https://openalex.org/W4234868996","https://openalex.org/W4246769071","https://openalex.org/W4281662064","https://openalex.org/W4284884776","https://openalex.org/W4375863320","https://openalex.org/W4376871633","https://openalex.org/W4380538102","https://openalex.org/W4381248116","https://openalex.org/W4387079708","https://openalex.org/W4392155646","https://openalex.org/W4393991132","https://openalex.org/W4401441624","https://openalex.org/W4406299390","https://openalex.org/W4409544387","https://openalex.org/W4412677253","https://openalex.org/W4412882389","https://openalex.org/W4413051233","https://openalex.org/W4413992903","https://openalex.org/W7118378286"],"related_works":["https://openalex.org/W4389788201","https://openalex.org/W4411877565","https://openalex.org/W7143330432","https://openalex.org/W4413800163","https://openalex.org/W4414602811","https://openalex.org/W7133202518","https://openalex.org/W4414099386","https://openalex.org/W7139979068","https://openalex.org/W7202087528","https://openalex.org/W4412882389"],"abstract_inverted_index":{"Pilocarpus":[0],"microphyllus":[1],"(jaborandi)":[2],"is":[3,14],"an":[4,21],"endangered":[5],"plant":[6],"species":[7],"with":[8,65],"significant":[9],"bioeconomic":[10],"relevance,":[11],"as":[12],"it":[13],"the":[15,26,92,100,114],"main":[16],"known":[17],"source":[18],"of":[19,28,69,77,85,99],"pilocarpine,":[20],"alkaloid":[22],"widely":[23],"used":[24],"in":[25],"treatment":[27],"glaucoma":[29],"and":[30,48,72,118,128],"other":[31],"diseases.":[32],"Here,":[33],"we":[34],"present":[35],"a":[36,66,73,108],"functionally":[37,89],"annotated,":[38],"haplotype-phased,":[39],"chromosome-level":[40],"genome":[41,53,102,106],"for":[42,112],"P.":[43],"microphyllus,":[44],"combining":[45],"PacBio":[46],"HiFi":[47],"Hi-C":[49],"sequencing.":[50],"The":[51],"final":[52],"assembly":[54],"spans":[55],"2.6":[56],"Gb":[57],"anchored":[58],"into":[59],"22":[60],"chromosomes":[61],"across":[62],"95":[63],"scaffolds,":[64],"scaffold":[67],"N50":[68],"120.9":[70],"Mb":[71],"BUSCO":[74],"completeness":[75],"score":[76],"99.66%.":[78],"We":[79],"obtained":[80],"28,319":[81],"unique":[82],"protein-coding":[83],"loci,":[84],"which":[86],"28,090":[87],"were":[88],"annotated":[90],"to":[91,125],"RefSeq":[93],"database.":[94],"Repetitive":[95],"sequences":[96],"constituted":[97],"88.98%":[98],"total":[101],"length.":[103],"This":[104],"near-T2T":[105],"provides":[107],"robust":[109],"molecular":[110],"foundation":[111],"investigating":[113],"pilocarpine":[115],"biosynthetic":[116],"pathway":[117],"supports":[119],"future":[120],"population-level":[121],"studies,":[122],"thereby":[123],"contributing":[124],"improved":[126],"management":[127],"conservation":[129],"strategies.":[130]},"counts_by_year":[{"year":2026,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2026-03-27T00:00:00"}