{"id":"https://openalex.org/W7140193707","doi":"https://doi.org/10.1097/01.ccm.0001185204.88862.ea","title":"802: RACIAL DISPARITIES IN ICU VENTILATION FOR COPD: A RETROSPECTIVE STUDY USING MIMIC-IV DATA","display_name":"802: RACIAL DISPARITIES IN ICU VENTILATION FOR COPD: A RETROSPECTIVE STUDY USING MIMIC-IV DATA","publication_year":2026,"publication_date":"2026-03-01","ids":{"openalex":"https://openalex.org/W7140193707","doi":"https://doi.org/10.1097/01.ccm.0001185204.88862.ea"},"language":"en","primary_location":{"id":"doi:10.1097/01.ccm.0001185204.88862.ea","doi":"https://doi.org/10.1097/01.ccm.0001185204.88862.ea","is_oa":false,"landing_page_url":"https://doi.org/10.1097/01.ccm.0001185204.88862.ea","pdf_url":null,"source":{"id":"https://openalex.org/S108732581","display_name":"Critical Care Medicine","issn_l":"0090-3493","issn":["0090-3493","1530-0293"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Critical Care Medicine","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5146827782","display_name":"Jeffrey Chen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I184840846","display_name":"Virginia Commonwealth University","ror":"https://ror.org/02nkdxk79","country_code":"US","type":"education","lineage":["https://openalex.org/I184840846"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jeffrey Chen","raw_affiliation_strings":["School of Medicine, Virginia Commonwealth University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Medicine, Virginia Commonwealth University","institution_ids":["https://openalex.org/I184840846"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5096772302","display_name":"Konrad McKalip","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I184840846","display_name":"Virginia Commonwealth University","ror":"https://ror.org/02nkdxk79","country_code":"US","type":"education","lineage":["https://openalex.org/I184840846"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Konrad McKalip","raw_affiliation_strings":["School of Medicine, Virginia Commonwealth University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Medicine, Virginia Commonwealth University","institution_ids":["https://openalex.org/I184840846"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5118803222","display_name":"Nicole Lulkin","orcid":"https://orcid.org/0009-0008-7649-8809","observed_orcids":["https://orcid.org/0009-0008-7649-8809"]},"institutions":[{"id":"https://openalex.org/I184840846","display_name":"Virginia Commonwealth University","ror":"https://ror.org/02nkdxk79","country_code":"US","type":"education","lineage":["https://openalex.org/I184840846"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Nicole Lulkin","raw_affiliation_strings":["School of Medicine, Virginia Commonwealth University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Medicine, Virginia Commonwealth University","institution_ids":["https://openalex.org/I184840846"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031401755","display_name":"Leo Anthony Celi","orcid":"https://orcid.org/0000-0001-6712-6626","observed_orcids":["https://orcid.org/0000-0001-6712-6626"]},"institutions":[{"id":"https://openalex.org/I1316535847","display_name":"Beth Israel Deaconess Medical Center","ror":"https://ror.org/04drvxt59","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1316535847"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Leo Anthony Celi","raw_affiliation_strings":["Beth Israel Deaconess Medical Center BIDMC"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Beth Israel Deaconess Medical Center BIDMC","institution_ids":["https://openalex.org/I1316535847"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5013963892","display_name":"Danai Khemasuwan","orcid":"https://orcid.org/0000-0003-4735-6285","observed_orcids":["https://orcid.org/0000-0003-4735-6285"]},"institutions":[{"id":"https://openalex.org/I184840846","display_name":"Virginia Commonwealth University","ror":"https://ror.org/02nkdxk79","country_code":"US","type":"education","lineage":["https://openalex.org/I184840846"]},{"id":"https://openalex.org/I72019824","display_name":"Virginia Commonwealth University Medical Center","ror":"https://ror.org/057xmsr27","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I72019824"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Danai Khemasuwan","raw_affiliation_strings":["Department of Internal Medicine, Virginia Commonwealth University Health"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, Virginia Commonwealth University Health","institution_ids":["https://openalex.org/I184840846","https://openalex.org/I72019824"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.16436573,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"54","issue":"3S","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10322","display_name":"Respiratory Support and Mechanisms","score":0.5687999725341797,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10322","display_name":"Respiratory Support and Mechanisms","score":0.5687999725341797,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10143","display_name":"Chronic Obstructive Pulmonary Disease (COPD) Research","score":0.25850000977516174,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10235","display_name":"Health disparities and outcomes","score":0.04989999905228615,"subfield":{"id":"https://openalex.org/subfields/3306","display_name":"Health"},"field":{"id":"https://openalex.org/fields/33","display_name":"Social Sciences"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/racial-disparities","display_name":"racial disparities","score":0.9900000095367432},{"id":"https://openalex.org/keywords/invasive-mechanical-ventilation","display_name":"invasive mechanical ventilation","score":0.9340000152587891},{"id":"https://openalex.org/keywords/chronic-obstructive-pulmonary-disease","display_name":"chronic obstructive pulmonary disease","score":0.9850000143051147},{"id":"https://openalex.org/keywords/black-patients","display_name":"Black patients","score":0.6159999966621399},{"id":"https://openalex.org/keywords/intensive-care-unit-patients","display_name":"intensive care unit patients","score":0.5899999737739563},{"id":"https://openalex.org/keywords/socioeconomic-status","display_name":"socioeconomic status","score":0.8090000152587891},{"id":"https://openalex.org/keywords/comorbidity","display_name":"comorbidities","score":0.8709999918937683},{"id":"https://openalex.org/keywords/disease-severity","display_name":"disease severity","score":0.9739999771118164},{"id":"https://openalex.org/keywords/targeted-maximum-likelihood-estimation","display_name":"targeted maximum likelihood estimation","score":0.6299999952316284},{"id":"https://openalex.org/keywords/propensity-score-adjustment","display_name":"propensity score adjustment","score":0.7049999833106995},{"id":"https://openalex.org/keywords/health-equity","display_name":"health equity","score":0.4449999928474426},{"id":"https://openalex.org/keywords/mimic-iv","display_name":"MIMIC-IV","score":0.8209999799728394}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9664000272750854},{"id":"https://openalex.org/C167135981","wikidata":"https://www.wikidata.org/wiki/Q2146302","display_name":"Retrospective cohort study","level":2,"score":0.7803000211715698},{"id":"https://openalex.org/C194828623","wikidata":"https://www.wikidata.org/wiki/Q2861470","display_name":"Emergency medicine","level":1,"score":0.6498000025749207},{"id":"https://openalex.org/C2777080012","wikidata":"https://www.wikidata.org/wiki/Q3766250","display_name":"Mechanical ventilation","level":2,"score":0.5246999859809875},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.5152999758720398},{"id":"https://openalex.org/C200457457","wikidata":"https://www.wikidata.org/wiki/Q584049","display_name":"Ventilation (architecture)","level":2,"score":0.4961000084877014},{"id":"https://openalex.org/C545542383","wikidata":"https://www.wikidata.org/wiki/Q2751242","display_name":"Medical emergency","level":1,"score":0.37599998712539673},{"id":"https://openalex.org/C2779473830","wikidata":"https://www.wikidata.org/wiki/Q1540899","display_name":"MEDLINE","level":2,"score":0.3564999997615814},{"id":"https://openalex.org/C2987404301","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care","level":2,"score":0.30309998989105225},{"id":"https://openalex.org/C3019440749","wikidata":"https://www.wikidata.org/wiki/Q855172","display_name":"Noninvasive ventilation","level":3,"score":0.2922999858856201}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1097/01.ccm.0001185204.88862.ea","doi":"https://doi.org/10.1097/01.ccm.0001185204.88862.ea","is_oa":false,"landing_page_url":"https://doi.org/10.1097/01.ccm.0001185204.88862.ea","pdf_url":null,"source":{"id":"https://openalex.org/S108732581","display_name":"Critical Care Medicine","issn_l":"0090-3493","issn":["0090-3493","1530-0293"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Critical Care Medicine","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"},{"score":0.9629999995231628,"display_name":"Reduced inequalities","id":"https://metadata.un.org/sdg/10"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2012117744","https://openalex.org/W4387241272","https://openalex.org/W4389129382","https://openalex.org/W4308101843","https://openalex.org/W2265317366","https://openalex.org/W4250104906","https://openalex.org/W4308231994","https://openalex.org/W4409053683","https://openalex.org/W4387609899","https://openalex.org/W4303984643"],"abstract_inverted_index":{"Introduction:":[0],"Prior":[1],"studies":[2],"suggest":[3],"Black":[4,98,175,205,261,289],"ICU":[5,37,78,94,116],"patients":[6,38,79,176,206,216,262,291],"may":[7],"receive":[8],"invasive":[9],"mechanical":[10],"ventilation":[11],"(IMV)":[12],"less":[13],"often":[14],"than":[15,214,296],"White":[16,163,215,297],"patients,":[17,298],"but":[18,227,255,299],"the":[19,68,93,115,274],"role":[20],"of":[21,105,112,131,172,211],"clinical":[22],"versus":[23],"structural":[24,313],"factors":[25],"remains":[26],"unclear.":[27],"This":[28],"study":[29,66],"examines":[30],"racial":[31,73,320],"disparities":[32,74],"in":[33,75,184,276],"IMV":[34,76,213,294],"use":[35],"among":[36,77],"with":[39,80,168,199],"chronic":[40],"obstructive":[41],"pulmonary":[42],"disease":[43],"(COPD)":[44],"and":[45,52,88,95,133,141,165,188,237],"evaluates":[46],"whether":[47],"adjusting":[48,233],"for":[49,57,234,260],"clinical,":[50,186],"demographic,":[51],"illness":[53,189,328],"severity":[54,130,190,238,329],"variables":[55,239],"accounts":[56],"observed":[58],"differences.":[59],"Methods:":[60],"We":[61,118],"conducted":[62],"a":[63,102,169,253],"retrospective":[64],"cohort":[65,104,160],"using":[67,135],"MIMIC-IV":[69],"database":[70],"to":[71,92,182,197,269,273,286],"assess":[72],"COPD.":[81],"Patients":[82],"were":[83,324],"identified":[84],"by":[85,327],"ICD-9/10":[86],"codes":[87],"included":[89],"if":[90],"admitted":[91],"self-identified":[96],"as":[97],"or":[99],"White,":[100],"yielding":[101],"final":[103],"1,961.":[106],"The":[107,159],"primary":[108],"outcome":[109],"was":[110,161,180,302],"receipt":[111],"IV":[113],"during":[114],"stay.":[117],"applied":[119],"stepwise":[120],"adjustment":[121],"across":[122],"five":[123],"covariate":[124,306],"domains":[125],"(demographics,":[126],"socioeconomic":[127],"status,":[128],"comorbidities,":[129],"illness,":[132],"anthropometrics)":[134],"propensity":[136],"score":[137,309],"models,":[138,204],"logistic":[139,203],"regression,":[140],"targeted":[142],"maximum":[143],"likelihood":[144],"estimation":[145],"(TMLE).":[146],"Isolated":[147],"domain":[148],"analyses":[149],"assessed":[150],"each":[151],"factor\u2019s":[152],"independent":[153],"impact":[154],"on":[155],"disparity":[156,229,301],"attenuation.":[157],"Results:":[158],"predominantly":[162],"(82.9%)":[164],"male":[166],"(55.1%),":[167],"median":[170],"age":[171],"69":[173],"years.":[174],"comprised":[177],"17.1%.":[178],"Race":[179],"linked":[181],"differences":[183],"baseline":[185],"socioeconomic,":[187,235],"characteristics":[191],"(baseline":[192],"pseudo-R2":[193],"increased":[194],"from":[195],"0.01":[196],"0.09":[198],"full":[200],"adjustment).":[201],"In":[202],"initially":[207],"had":[208,292],"lower":[209,293],"odds":[210],"receiving":[212],"(adjusted":[217],"OR":[218,242],"=":[219,243,249,264,281],"0.49;":[220],"95%":[221,245,266,283],"CI:":[222,246,267,284],"0.10\u20132.30;":[223],"p":[224,248],"<":[225],"0.001),":[226],"this":[228,300],"became":[230],"non-significant":[231],"after":[232,305],"comorbidity,":[236],"(fully":[240],"adjusted":[241,278],"0.86;":[244],"0.67\u20131.09;":[247],"0.224).":[250],"TMLE":[251,316],"showed":[252,317],"lower,":[254],"not":[256,303],"significant,":[257],"unadjusted":[258],"risk":[259],"(RD":[263,280],"\u20130.17;":[265],"\u20130.51":[268],"0.17),":[270],"which":[271],"attenuated":[272],"null":[275],"fully":[277],"models":[279,310],"\u20130.03;":[282],"\u20131.81":[285],"1.74).":[287],"Conclusions:":[288],"COPD":[290],"rates":[295],"significant":[304],"adjustment.":[307],"Propensity":[308],"suggested":[311],"modest":[312],"confounding,":[314],"while":[315],"no":[318],"residual":[319],"effect":[321],"post-adjustment.":[322],"Differences":[323],"largely":[325],"mediated":[326],"at":[330],"presentation.":[331]},"counts_by_year":[],"updated_date":"2026-10-12T09:40:04.860316","created_date":"2026-03-25T00:00:00"}