{"id":"https://openalex.org/W7140190902","doi":"https://doi.org/10.3389/fvets.2026.1752459","title":"Natural SARS-CoV-2 infection in farmed minks (Neovison vison) causes lung pathology, systemic viral spread, and transmission risk, even in asymptomatic animals","display_name":"Natural SARS-CoV-2 infection in farmed minks (Neovison vison) causes lung pathology, systemic viral spread, and transmission risk, even in asymptomatic animals","publication_year":2026,"publication_date":"2026-03-24","ids":{"openalex":"https://openalex.org/W7140190902","doi":"https://doi.org/10.3389/fvets.2026.1752459","pmid":"https://pubmed.ncbi.nlm.nih.gov/41953113","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/13054983"},"language":"en","primary_location":{"id":"doi:10.3389/fvets.2026.1752459","doi":"https://doi.org/10.3389/fvets.2026.1752459","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fvets.2026.1752459","pdf_url":"https://public-pages-files-2025.frontiersin.org/journals/veterinary-science/articles/10.3389/fvets.2026.1752459/pdf","source":{"id":"https://openalex.org/S2594976040","display_name":"Frontiers in Veterinary Science","issn_l":"2297-1769","issn":["2297-1769"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Veterinary Science","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://public-pages-files-2025.frontiersin.org/journals/veterinary-science/articles/10.3389/fvets.2026.1752459/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5048121398","display_name":"Sandra Vreman","orcid":"https://orcid.org/0000-0003-0779-6251","observed_orcids":["https://orcid.org/0000-0003-0779-6251"]},"institutions":[{"id":"https://openalex.org/I913481162","display_name":"Wageningen University & Research","ror":"https://ror.org/04qw24q55","country_code":"NL","type":"education","lineage":["https://openalex.org/I913481162"]}],"countries":["NL"],"is_corresponding":true,"raw_author_name":"Sandra Vreman","raw_affiliation_strings":["Wageningen Bioveterinary Research, Wageningen University and Research"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Wageningen Bioveterinary Research, Wageningen University and Research","institution_ids":["https://openalex.org/I913481162"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047811819","display_name":"Giuseppe Giglia","orcid":"https://orcid.org/0000-0002-3544-8812","observed_orcids":["https://orcid.org/0000-0002-3544-8812"]},"institutions":[{"id":"https://openalex.org/I193662353","display_name":"Utrecht University","ror":"https://ror.org/04pp8hn57","country_code":"NL","type":"education","lineage":["https://openalex.org/I193662353"]},{"id":"https://openalex.org/I27483092","display_name":"University of Perugia","ror":"https://ror.org/00x27da85","country_code":"IT","type":"education","lineage":["https://openalex.org/I27483092"]}],"countries":["IT","NL"],"is_corresponding":false,"raw_author_name":"Giuseppe Giglia","raw_affiliation_strings":["Department of Veterinary Medicine, University of Perugia","Division of Pathology, Department of Biomolecular Health Sciences, Faculty of Veterinary Medicine, Utrecht University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Veterinary Medicine, University of Perugia","institution_ids":["https://openalex.org/I27483092"]},{"raw_affiliation_string":"Division of Pathology, Department of Biomolecular Health Sciences, Faculty of Veterinary Medicine, Utrecht University","institution_ids":["https://openalex.org/I193662353"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074983073","display_name":"Robert Jan Molenaar","orcid":"https://orcid.org/0000-0003-0336-1226","observed_orcids":["https://orcid.org/0000-0003-0336-1226"]},"institutions":[{"id":"https://openalex.org/I4210119978","display_name":"Royal GD (Netherlands)","ror":"https://ror.org/02j5ney70","country_code":"NL","type":"company","lineage":["https://openalex.org/I4210119978"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Robert-Jan Molenaar","raw_affiliation_strings":["Department of Poultry Health, Royal GD"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Poultry Health, Royal GD","institution_ids":["https://openalex.org/I4210119978"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043563240","display_name":"Renate W. Hakze\u2010van der Honing","orcid":"https://orcid.org/0000-0001-7621-2729","observed_orcids":["https://orcid.org/0000-0001-7621-2729"]},"institutions":[{"id":"https://openalex.org/I913481162","display_name":"Wageningen University & Research","ror":"https://ror.org/04qw24q55","country_code":"NL","type":"education","lineage":["https://openalex.org/I913481162"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Renate Hakze-van der Honing","raw_affiliation_strings":["Wageningen Bioveterinary Research, Wageningen University and Research"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Wageningen Bioveterinary Research, Wageningen University and Research","institution_ids":["https://openalex.org/I913481162"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031211693","display_name":"Eveline M. Delemarre","orcid":"https://orcid.org/0000-0002-4310-0998","observed_orcids":["https://orcid.org/0000-0002-4310-0998"]},"institutions":[{"id":"https://openalex.org/I3018483916","display_name":"University Medical Center Utrecht","ror":"https://ror.org/0575yy874","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I3018483916"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Eveline M. Delemarre","raw_affiliation_strings":["Center for Translational Immunology, University Medical Center Utrecht"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Translational Immunology, University Medical Center Utrecht","institution_ids":["https://openalex.org/I3018483916"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086290087","display_name":"Stefan Nierkens","orcid":"https://orcid.org/0000-0003-3406-817X","observed_orcids":["https://orcid.org/0000-0003-3406-817X"]},"institutions":[{"id":"https://openalex.org/I3018483916","display_name":"University Medical Center Utrecht","ror":"https://ror.org/0575yy874","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I3018483916"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Stefan Nierkens","raw_affiliation_strings":["Center for Translational Immunology, University Medical Center Utrecht"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Translational Immunology, University Medical Center Utrecht","institution_ids":["https://openalex.org/I3018483916"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022520156","display_name":"Katrin E. Wiese","orcid":"https://orcid.org/0000-0002-1603-2846","observed_orcids":["https://orcid.org/0000-0002-1603-2846"]},"institutions":[{"id":"https://openalex.org/I913481162","display_name":"Wageningen University & Research","ror":"https://ror.org/04qw24q55","country_code":"NL","type":"education","lineage":["https://openalex.org/I913481162"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Katrin E. Wiese","raw_affiliation_strings":["Wageningen Bioveterinary Research, Wageningen University and Research"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Wageningen Bioveterinary Research, Wageningen University and Research","institution_ids":["https://openalex.org/I913481162"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058342002","display_name":"Gianfilippo Agliani","orcid":"https://orcid.org/0000-0002-4347-4922","observed_orcids":["https://orcid.org/0000-0002-4347-4922"]},"institutions":[{"id":"https://openalex.org/I193662353","display_name":"Utrecht University","ror":"https://ror.org/04pp8hn57","country_code":"NL","type":"education","lineage":["https://openalex.org/I193662353"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Gianfilippo Agliani","raw_affiliation_strings":["Division of Pathology, Department of Biomolecular Health Sciences, Faculty of Veterinary Medicine, Utrecht University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Pathology, Department of Biomolecular Health Sciences, Faculty of Veterinary Medicine, Utrecht University","institution_ids":["https://openalex.org/I193662353"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112420075","display_name":"Wim H. M. van der Poel","orcid":"https://orcid.org/0000-0002-7498-8002","observed_orcids":["https://orcid.org/0000-0002-7498-8002"]},"institutions":[{"id":"https://openalex.org/I913481162","display_name":"Wageningen University & Research","ror":"https://ror.org/04qw24q55","country_code":"NL","type":"education","lineage":["https://openalex.org/I913481162"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Wim van der Poel","raw_affiliation_strings":["Wageningen Bioveterinary Research, Wageningen University and Research"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Wageningen Bioveterinary Research, Wageningen University and Research","institution_ids":["https://openalex.org/I913481162"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040714564","display_name":"Frank J. M. van Kuppeveld","orcid":"https://orcid.org/0000-0001-5800-749X","observed_orcids":["https://orcid.org/0000-0001-5800-749X"]},"institutions":[{"id":"https://openalex.org/I193662353","display_name":"Utrecht University","ror":"https://ror.org/04pp8hn57","country_code":"NL","type":"education","lineage":["https://openalex.org/I193662353"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Frank van Kuppeveld","raw_affiliation_strings":["Section of Virology, Division of Infectious Diseases & Immunology, Department of Biomolecular Health Sciences, Faculty of Veterinary Medicine, Utrecht University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Section of Virology, Division of Infectious Diseases & Immunology, Department of Biomolecular Health Sciences, Faculty of Veterinary Medicine, Utrecht University","institution_ids":["https://openalex.org/I193662353"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080132990","display_name":"Berend\u2010Jan Bosch","orcid":"https://orcid.org/0000-0002-3864-232X","observed_orcids":["https://orcid.org/0000-0002-3864-232X"]},"institutions":[{"id":"https://openalex.org/I193662353","display_name":"Utrecht University","ror":"https://ror.org/04pp8hn57","country_code":"NL","type":"education","lineage":["https://openalex.org/I193662353"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Berend Jan Bosch","raw_affiliation_strings":["Section of Virology, Division of Infectious Diseases & Immunology, Department of Biomolecular Health Sciences, Faculty of Veterinary Medicine, Utrecht University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Section of Virology, Division of Infectious Diseases & Immunology, Department of Biomolecular Health Sciences, Faculty of Veterinary Medicine, Utrecht University","institution_ids":["https://openalex.org/I193662353"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009977774","display_name":"Erwin de Bruin","orcid":"https://orcid.org/0000-0003-0826-5102","observed_orcids":["https://orcid.org/0000-0003-0826-5102"]},"institutions":[{"id":"https://openalex.org/I193662353","display_name":"Utrecht University","ror":"https://ror.org/04pp8hn57","country_code":"NL","type":"education","lineage":["https://openalex.org/I193662353"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Erwin de Bruin","raw_affiliation_strings":["Division of Pathology, Department of Biomolecular Health Sciences, Faculty of Veterinary Medicine, Utrecht University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Pathology, Department of Biomolecular Health Sciences, Faculty of Veterinary Medicine, Utrecht University","institution_ids":["https://openalex.org/I193662353"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111833376","display_name":"Andrea Gr\u00f6ne","orcid":"https://orcid.org/0000-0002-6296-1128","observed_orcids":["https://orcid.org/0000-0002-6296-1128"]},"institutions":[{"id":"https://openalex.org/I193662353","display_name":"Utrecht University","ror":"https://ror.org/04pp8hn57","country_code":"NL","type":"education","lineage":["https://openalex.org/I193662353"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Andrea Gr\u00f6ne","raw_affiliation_strings":["Division of Pathology, Department of Biomolecular Health Sciences, Faculty of Veterinary Medicine, Utrecht University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Pathology, Department of Biomolecular Health Sciences, Faculty of Veterinary Medicine, Utrecht University","institution_ids":["https://openalex.org/I193662353"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065695135","display_name":"Naomi D. de Bruijn","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210119978","display_name":"Royal GD (Netherlands)","ror":"https://ror.org/02j5ney70","country_code":"NL","type":"company","lineage":["https://openalex.org/I4210119978"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Naomi de Bruijn","raw_affiliation_strings":["Department of Poultry Health, Royal GD"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Poultry Health, Royal GD","institution_ids":["https://openalex.org/I4210119978"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5008146809","display_name":"Judith M. A. van den Brand","orcid":"https://orcid.org/0000-0001-8420-5406","observed_orcids":["https://orcid.org/0000-0001-8420-5406"]},"institutions":[{"id":"https://openalex.org/I193662353","display_name":"Utrecht University","ror":"https://ror.org/04pp8hn57","country_code":"NL","type":"education","lineage":["https://openalex.org/I193662353"]}],"countries":["NL"],"is_corresponding":true,"raw_author_name":"Judith M.A. van den Brand","raw_affiliation_strings":["Division of Pathology, Department of Biomolecular Health Sciences, Faculty of Veterinary Medicine, Utrecht University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Pathology, Department of Biomolecular Health Sciences, Faculty of Veterinary Medicine, Utrecht University","institution_ids":["https://openalex.org/I193662353"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5008146809","https://openalex.org/A5048121398"],"corresponding_institution_ids":["https://openalex.org/I193662353","https://openalex.org/I913481162"],"apc_list":{"value":3150,"currency":"CHF","value_usd":3801},"apc_paid":{"value":3150,"currency":"CHF","value_usd":3801},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"13","issue":null,"first_page":"1752459","last_page":"1752459"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10118","display_name":"SARS-CoV-2 and COVID-19 Research","score":0.7993000149726868,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10118","display_name":"SARS-CoV-2 and COVID-19 Research","score":0.7993000149726868,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11495","display_name":"Animal Virus Infections Studies","score":0.16300000250339508,"subfield":{"id":"https://openalex.org/subfields/1103","display_name":"Animal Science and Zoology"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12492","display_name":"Zoonotic diseases and public health","score":0.017999999225139618,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/sars-cov-2","display_name":"SARS-CoV-2","score":0.9750000238418579},{"id":"https://openalex.org/keywords/farmed-mink","display_name":"farmed mink","score":0.8519999980926514},{"id":"https://openalex.org/keywords/american-mink","display_name":"American mink","score":0.9700000286102295},{"id":"https://openalex.org/keywords/interstitial-lung-disease","display_name":"interstitial lung disease","score":0.8080000281333923},{"id":"https://openalex.org/keywords/pulmonary-pathology","display_name":"lung pathology","score":0.8500000238418579},{"id":"https://openalex.org/keywords/asymptomatic-infection","display_name":"asymptomatic infection","score":0.734000027179718},{"id":"https://openalex.org/keywords/viral-spread","display_name":"viral spread","score":0.5120000243186951},{"id":"https://openalex.org/keywords/zoonotic-transmission","display_name":"zoonotic transmission","score":0.8420000076293945},{"id":"https://openalex.org/keywords/serology","display_name":"serology","score":0.5320000052452087},{"id":"https://openalex.org/keywords/viral-load","display_name":"viral load","score":0.43799999356269836},{"id":"https://openalex.org/keywords/wildlife-reservoirs","display_name":"wildlife reservoirs","score":0.37599998712539673},{"id":"https://openalex.org/keywords/sars-cov-2-variants","display_name":"SARS-CoV-2 variants","score":0.5789999961853027}],"concepts":[{"id":"https://openalex.org/C52991690","wikidata":"https://www.wikidata.org/wiki/Q1740042","display_name":"Culling","level":3,"score":0.8174999952316284},{"id":"https://openalex.org/C116675565","wikidata":"https://www.wikidata.org/wiki/Q3241045","display_name":"Outbreak","level":2,"score":0.6676999926567078},{"id":"https://openalex.org/C2777910003","wikidata":"https://www.wikidata.org/wiki/Q1707292","display_name":"Asymptomatic","level":2,"score":0.5949000120162964},{"id":"https://openalex.org/C2777914695","wikidata":"https://www.wikidata.org/wiki/Q12192","display_name":"Pneumonia","level":2,"score":0.590499997138977},{"id":"https://openalex.org/C2777648638","wikidata":"https://www.wikidata.org/wiki/Q57751738","display_name":"Coronavirus","level":5,"score":0.5760999917984009},{"id":"https://openalex.org/C113280763","wikidata":"https://www.wikidata.org/wiki/Q2326546","display_name":"Subclinical infection","level":2,"score":0.5501000285148621},{"id":"https://openalex.org/C2777714996","wikidata":"https://www.wikidata.org/wiki/Q7886","display_name":"Lung","level":2,"score":0.515999972820282},{"id":"https://openalex.org/C12914427","wikidata":"https://www.wikidata.org/wiki/Q7933612","display_name":"Viral shedding","level":3,"score":0.49639999866485596},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.4864000082015991},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.47940000891685486},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4399000108242035},{"id":"https://openalex.org/C2778158872","wikidata":"https://www.wikidata.org/wiki/Q2603200","display_name":"Viral pneumonia","level":5,"score":0.4374000132083893},{"id":"https://openalex.org/C761482","wikidata":"https://www.wikidata.org/wiki/Q118093","display_name":"Transmission (telecommunications)","level":2,"score":0.43529999256134033},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4198000133037567},{"id":"https://openalex.org/C534529494","wikidata":"https://www.wikidata.org/wiki/Q7891","display_name":"Respiratory system","level":2,"score":0.4009999930858612},{"id":"https://openalex.org/C2776178081","wikidata":"https://www.wikidata.org/wiki/Q3286546","display_name":"Respiratory disease","level":3,"score":0.39820000529289246},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.3837999999523163},{"id":"https://openalex.org/C2779764123","wikidata":"https://www.wikidata.org/wiki/Q7972881","display_name":"Wasting","level":2,"score":0.3763999938964844},{"id":"https://openalex.org/C2779192065","wikidata":"https://www.wikidata.org/wiki/Q19707","display_name":"Donkey","level":2,"score":0.36500000953674316},{"id":"https://openalex.org/C9418649","wikidata":"https://www.wikidata.org/wiki/Q5275407","display_name":"Diffuse alveolar damage","level":4,"score":0.357699990272522},{"id":"https://openalex.org/C2522874641","wikidata":"https://www.wikidata.org/wiki/Q808","display_name":"Virus","level":2,"score":0.35190001130104065},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.3431999981403351},{"id":"https://openalex.org/C2779673711","wikidata":"https://www.wikidata.org/wiki/Q2633267","display_name":"Atypical pneumonia","level":3,"score":0.30570000410079956},{"id":"https://openalex.org/C544855455","wikidata":"https://www.wikidata.org/wiki/Q1070952","display_name":"Histopathology","level":2,"score":0.29420000314712524},{"id":"https://openalex.org/C2780727368","wikidata":"https://www.wikidata.org/wiki/Q1928978","display_name":"Viral disease","level":3,"score":0.27480000257492065},{"id":"https://openalex.org/C2779720271","wikidata":"https://www.wikidata.org/wiki/Q179422","display_name":"Lymph","level":2,"score":0.260699987411499},{"id":"https://openalex.org/C2911126609","wikidata":"https://www.wikidata.org/wiki/Q6003455","display_name":"Wasting Syndrome","level":3,"score":0.2563999891281128},{"id":"https://openalex.org/C2780931953","wikidata":"https://www.wikidata.org/wiki/Q9371","display_name":"Spleen","level":2,"score":0.2529999911785126}],"mesh":[],"locations_count":7,"locations":[{"id":"doi:10.3389/fvets.2026.1752459","doi":"https://doi.org/10.3389/fvets.2026.1752459","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fvets.2026.1752459","pdf_url":"https://public-pages-files-2025.frontiersin.org/journals/veterinary-science/articles/10.3389/fvets.2026.1752459/pdf","source":{"id":"https://openalex.org/S2594976040","display_name":"Frontiers in Veterinary Science","issn_l":"2297-1769","issn":["2297-1769"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Veterinary Science","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:13054983","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13054983/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13054983/pdf/fvets-13-1752459.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Front Vet Sci","raw_type":"Text"},{"id":"pmid:41953113","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/41953113","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in veterinary science","raw_type":"Journal Article"},{"id":"pmh:oai:library.wur.nl:wurpubs/09f4c1f4-5de5-4926-8509-43367ed78640","doi":null,"is_oa":true,"landing_page_url":"https://research.wur.nl/en/publications/natural-sars-cov-2-infection-in-farmed-minks-neovison-vison-cause","pdf_url":"https://edepot.wur.nl/716312","source":{"id":"https://openalex.org/S4210201231","display_name":"Socio-Environmental Systems Modeling","issn_l":"2663-3027","issn":["2663-3027"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"ISSN: 2297-1769","raw_type":"Article/Letter to editor"},{"id":"pmh:oai:doaj.org/article:378fdd044eb646b8aaf99c580a9dc742","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/378fdd044eb646b8aaf99c580a9dc742","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Frontiers in Veterinary Science, Vol 13 (2026)","raw_type":"article"},{"id":"pmh:oai:dspace.library.uu.nl:1874/483855","doi":null,"is_oa":true,"landing_page_url":"https://dspace.library.uu.nl/handle/1874/483855","pdf_url":null,"source":{"id":"https://openalex.org/S4306401649","display_name":"Utrecht University Repository (Utrecht University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I193662353","host_organization_name":"Utrecht University","host_organization_lineage":["https://openalex.org/I193662353"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Article"},{"id":"pmh:oai:dspace.library.uu.nl:1874/484598","doi":null,"is_oa":true,"landing_page_url":"https://dspace.library.uu.nl/handle/1874/484598","pdf_url":null,"source":{"id":"https://openalex.org/S4306401649","display_name":"Utrecht University Repository (Utrecht University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I193662353","host_organization_name":"Utrecht University","host_organization_lineage":["https://openalex.org/I193662353"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Article"}],"best_oa_location":{"id":"doi:10.3389/fvets.2026.1752459","doi":"https://doi.org/10.3389/fvets.2026.1752459","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fvets.2026.1752459","pdf_url":"https://public-pages-files-2025.frontiersin.org/journals/veterinary-science/articles/10.3389/fvets.2026.1752459/pdf","source":{"id":"https://openalex.org/S2594976040","display_name":"Frontiers in Veterinary Science","issn_l":"2297-1769","issn":["2297-1769"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Veterinary Science","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9537000060081482,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7140190902.pdf","grobid_xml":"https://content.openalex.org/works/W7140190902.grobid-xml"},"referenced_works_count":50,"referenced_works":["https://openalex.org/W70469965","https://openalex.org/W1602717038","https://openalex.org/W1967986697","https://openalex.org/W2010917880","https://openalex.org/W2095170040","https://openalex.org/W2129542667","https://openalex.org/W2153866915","https://openalex.org/W2170195562","https://openalex.org/W2588404756","https://openalex.org/W2806299069","https://openalex.org/W3001195213","https://openalex.org/W3009885589","https://openalex.org/W3023698680","https://openalex.org/W3034306775","https://openalex.org/W3034813444","https://openalex.org/W3035191535","https://openalex.org/W3036853141","https://openalex.org/W3037229948","https://openalex.org/W3038836337","https://openalex.org/W3043405722","https://openalex.org/W3089933733","https://openalex.org/W3099833776","https://openalex.org/W3102258632","https://openalex.org/W3104695222","https://openalex.org/W3108050888","https://openalex.org/W3110743867","https://openalex.org/W3120969844","https://openalex.org/W3123508390","https://openalex.org/W3127508468","https://openalex.org/W3135265863","https://openalex.org/W3152527271","https://openalex.org/W3170500760","https://openalex.org/W3174834250","https://openalex.org/W3182552419","https://openalex.org/W3198684284","https://openalex.org/W3207237055","https://openalex.org/W3214567236","https://openalex.org/W3216684143","https://openalex.org/W4205521972","https://openalex.org/W4206909303","https://openalex.org/W4210308762","https://openalex.org/W4214712460","https://openalex.org/W4221052027","https://openalex.org/W4317532237","https://openalex.org/W4362506553","https://openalex.org/W4384501730","https://openalex.org/W4387613427","https://openalex.org/W4406213903","https://openalex.org/W4409986667","https://openalex.org/W4413182653"],"related_works":["https://openalex.org/W3043405722","https://openalex.org/W3214567236","https://openalex.org/W4206909303","https://openalex.org/W3170500760","https://openalex.org/W3198684284","https://openalex.org/W4410948901","https://openalex.org/W3034813444","https://openalex.org/W7166319150","https://openalex.org/W3194557310","https://openalex.org/W4390587698"],"abstract_inverted_index":{"Introduction":[0],"In":[1],"2020,":[2],"the":[3,23,45,86,97,111,118,191,206,220,233,263,270,275,297,348],"first":[4],"disease":[5,32,54,103],"outbreak":[6],"of":[7,91,99,120,133,148,277,304,350],"severe":[8,202,317,328],"acute":[9],"respiratory":[10,49,53],"syndrome":[11],"coronavirus":[12],"2":[13],"(SARS-CoV-2)":[14],"in":[15,22,28,33,43,52,56,125,205,219,228,239,248,262,269,281,334,347],"farmed":[16],"minks":[17,34,69,126,135,305],"(Neovison":[18],"vison)":[19],"was":[20,190],"reported":[21],"Netherlands,":[24],"followed":[25],"by":[26,37,215],"outbreaks":[27],"other":[29],"countries.":[30],"The":[31],"is":[35,67],"characterized":[36],"interstitial":[38,188],"pneumonia":[39,189],"and":[40,47,102,117,146,174,208,223,236,250,253,255,266,320,344],"viral":[41,100,216,243,322,345],"replication":[42],"both":[44],"upper":[46],"lower":[48],"tracts,":[50],"resulting":[51],"and,":[55],"some":[57],"cases,":[58],"death.":[59],"A":[60,131],"major":[61],"concern,":[62],"besides":[63],"animal":[64],"health":[65,144],"problems,":[66],"that":[68,187],"are":[70,331],"a":[71,77,293,340],"potential":[72,341],"reservoir":[73],"for":[74,80,88],"SARS-CoV-2,":[75],"with":[76,200,308,314],"zoonotic":[78,342],"impact":[79],"human":[81],"Coronavirus":[82],"Disease-19":[83],"(COVID-19),":[84],"underscoring":[85],"need":[87],"close":[89],"monitoring":[90],"infections.":[92],"Methods":[93],"To":[94],"better":[95],"understand":[96],"dynamics":[98],"spread":[101,346],"progression":[104],"after":[105],"natural":[106],"infection,":[107],"this":[108],"study":[109],"investigates":[110],"pathology,":[112],"immunohistochemistry,":[113],"virology,":[114],"serology,":[115],"proteomics,":[116],"presence":[119,276],"Aleutian":[121],"Disease":[122],"Virus":[123],"(ADV)":[124],"from":[127],"an":[128],"infected":[129,313],"farm.":[130],"total":[132],"45":[134],"were":[136,213,246,260,306],"divided":[137],"into":[138],"four":[139,198],"groups":[140],"based":[141],"on":[142,287,300],"clinical":[143,166,337,352],"status":[145],"time":[147],"sampling:":[149],"found":[150,175,247],"dead":[151,176],"before":[152],"culling":[153,161,169,178],"(FD,":[154],"n":[155,163,171,180],"=":[156,164,172,181],"15),":[157],"clinically":[158],"healthy":[159],"during":[160,168,177],"(NCSc,":[162],"10),":[165,173],"signs":[167],"(CSc,":[170],"(FDc,":[179],"10).":[182],"Results":[183],"Histopathological":[184,211],"examination":[185],"revealed":[186],"most":[192],"prominent":[193],"SARS-CoV-2-related":[194],"finding":[195],"across":[196,324],"all":[197,240,282],"groups,":[199,283],"more":[201],"lesions":[203,330],"seen":[204],"FD":[207],"FDc":[209,271],"groups.":[210,241,298],"changes":[212],"supported":[214],"antigen":[217],"expression":[218],"nose,":[221],"trachea,":[222],"lungs,":[224],"as":[225,227,232],"well":[226],"extra-respiratory":[229],"tissues":[230],"such":[231],"intestine,":[234,267],"spleen,":[235,264],"lymph":[237],"nodes,":[238],"Highest":[242],"RNA":[244],"levels":[245,259],"nasal":[249],"throat":[251],"swabs":[252],"nose":[254],"lung":[256,318,329],"tissues.":[257],"Lower":[258],"detected":[261],"liver,":[265],"especially":[268],"animals.":[272],"Serology":[273],"confirmed":[274],"SARS-CoV-2":[278,315],"specific":[279],"antibodies":[280],"whereas":[284],"immune-related":[285],"proteomics":[286],"whole":[288],"blood":[289],"did":[290],"not":[291],"show":[292],"significant":[294],"difference":[295],"between":[296],"Based":[299],"qPCR,":[301],"over":[302],"57%":[303],"co-infected":[307],"ADV.":[309],"Discussion":[310],"Minks":[311],"naturally":[312],"exhibit":[316],"pathology":[319],"high":[321],"loads":[323],"multiple":[325],"organs.":[326],"Additionally,":[327],"also":[332],"observed":[333],"animals":[335],"without":[336],"signs,":[338],"suggesting":[339],"risk":[343],"absence":[349],"any":[351],"signs.":[353]},"counts_by_year":[],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2026-03-25T00:00:00"}