{"id":"https://openalex.org/W7136233152","doi":"https://doi.org/10.6084/m9.figshare.4406600","title":"Additional file 4: of Synergistic effect of oridonin and a PI3K/mTOR inhibitor on the non-germinal center B cell-like subtype of diffuse large B cell lymphoma","display_name":"Additional file 4: of Synergistic effect of oridonin and a PI3K/mTOR inhibitor on the non-germinal center B cell-like subtype of diffuse large B cell lymphoma","publication_year":2016,"publication_date":"2016-01-01","ids":{"openalex":"https://openalex.org/W7136233152","doi":"https://doi.org/10.6084/m9.figshare.4406600"},"language":"en","primary_location":{"id":"doi:10.6084/m9.figshare.4406600","doi":"https://doi.org/10.6084/m9.figshare.4406600","is_oa":true,"landing_page_url":"https://doi.org/10.6084/m9.figshare.4406600","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"JournalArticle"},"volume":null,"type":"article","indexed_in":["datacite"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://doi.org/10.6084/m9.figshare.4406600","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5048826393","display_name":"Kai Qing","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Qing, Kai","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5129422353","display_name":"Zhen Jin","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jin, Zhen","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5129464257","display_name":"Wanbin Fu","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Fu, Wanbin","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032220368","display_name":"Wenfang Wang","orcid":"https://orcid.org/0000-0001-5667-239X","observed_orcids":["https://orcid.org/0000-0001-5667-239X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Wang, Wenfang","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5129640226","display_name":"Zhao Liu","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Liu, Zhao","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5129398797","display_name":"Xiaoyang Li","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Li, Xiaoyang","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5129417586","display_name":"Zizhen Xu","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Xu, Zizhen","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5129597245","display_name":"Junmin Li","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Li, Junmin","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.61988441,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10185","display_name":"Lymphoma Diagnosis and Treatment","score":0.9326000213623047,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10185","display_name":"Lymphoma Diagnosis and Treatment","score":0.9326000213623047,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10952","display_name":"PI3K/AKT/mTOR signaling in cancer","score":0.026399999856948853,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11157","display_name":"Chronic Lymphocytic Leukemia Research","score":0.009600000455975533,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/oridonin","display_name":"oridonin","score":1.0},{"id":"https://openalex.org/keywords/nvp-bez235","display_name":"NVP-BEZ235","score":0.9929999709129333},{"id":"https://openalex.org/keywords/pi3k-mtor-inhibitors","display_name":"PI3K/mTOR inhibitors","score":0.8989999890327454},{"id":"https://openalex.org/keywords/diffuse-large-b-cell-lymphoma","display_name":"diffuse large B-cell lymphoma","score":0.9810000061988831},{"id":"https://openalex.org/keywords/cell-cycle","display_name":"cell cycle","score":0.7250000238418579},{"id":"https://openalex.org/keywords/g0-g1-phase","display_name":"G0/G1 phase","score":0.8700000047683716},{"id":"https://openalex.org/keywords/drug-synergy","display_name":"drug synergy","score":0.6349999904632568}],"concepts":[{"id":"https://openalex.org/C2778559949","wikidata":"https://www.wikidata.org/wiki/Q2626074","display_name":"Diffuse large B-cell lymphoma","level":3,"score":0.6567000150680542},{"id":"https://openalex.org/C29537977","wikidata":"https://www.wikidata.org/wiki/Q188941","display_name":"Cell cycle","level":3,"score":0.5875999927520752},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.5746999979019165},{"id":"https://openalex.org/C553184892","wikidata":"https://www.wikidata.org/wiki/Q1141429","display_name":"Flow cytometry","level":2,"score":0.5590999722480774},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5099999904632568},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.5012000203132629},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.48240000009536743},{"id":"https://openalex.org/C2779338263","wikidata":"https://www.wikidata.org/wiki/Q208414","display_name":"Lymphoma","level":2,"score":0.4810999929904938},{"id":"https://openalex.org/C109316439","wikidata":"https://www.wikidata.org/wiki/Q246181","display_name":"Cytotoxicity","level":3,"score":0.3743000030517578},{"id":"https://openalex.org/C62112901","wikidata":"https://www.wikidata.org/wiki/Q189159","display_name":"Cell growth","level":2,"score":0.3497999906539917},{"id":"https://openalex.org/C2994037739","wikidata":"https://www.wikidata.org/wiki/Q188941","display_name":"Cell cycle progression","level":4,"score":0.3495999872684479},{"id":"https://openalex.org/C81885089","wikidata":"https://www.wikidata.org/wiki/Q189082","display_name":"Cell culture","level":2,"score":0.3479999899864197},{"id":"https://openalex.org/C2778453870","wikidata":"https://www.wikidata.org/wiki/Q188930","display_name":"B cell","level":3,"score":0.3424000144004822},{"id":"https://openalex.org/C3020616263","wikidata":"https://www.wikidata.org/wiki/Q1216998","display_name":"Tumor cells","level":2,"score":0.3206999897956848},{"id":"https://openalex.org/C2777257650","wikidata":"https://www.wikidata.org/wiki/Q4833719","display_name":"B-cell lymphoma","level":3,"score":0.3095000088214874},{"id":"https://openalex.org/C2986587452","wikidata":"https://www.wikidata.org/wiki/Q938438","display_name":"Statistical analysis","level":2,"score":0.3057999908924103},{"id":"https://openalex.org/C3019361144","wikidata":"https://www.wikidata.org/wiki/Q367359","display_name":"Negative control","level":2,"score":0.3005000054836273},{"id":"https://openalex.org/C2780339063","wikidata":"https://www.wikidata.org/wiki/Q5201367","display_name":"Cytometry","level":3,"score":0.2985999882221222},{"id":"https://openalex.org/C114684123","wikidata":"https://www.wikidata.org/wiki/Q419458","display_name":"CD3","level":4,"score":0.29339998960494995},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2847000062465668},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2669000029563904},{"id":"https://openalex.org/C2777066959","wikidata":"https://www.wikidata.org/wiki/Q869711","display_name":"Cricetulus","level":4,"score":0.26019999384880066},{"id":"https://openalex.org/C2780783641","wikidata":"https://www.wikidata.org/wiki/Q738686","display_name":"MTT assay","level":3,"score":0.2581000030040741},{"id":"https://openalex.org/C2776090121","wikidata":"https://www.wikidata.org/wiki/Q193529","display_name":"T cell","level":3,"score":0.25450000166893005},{"id":"https://openalex.org/C3019137385","wikidata":"https://www.wikidata.org/wiki/Q189159","display_name":"Cell survival","level":3,"score":0.2540999948978424},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.25099998712539673}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.6084/m9.figshare.4406600","doi":"https://doi.org/10.6084/m9.figshare.4406600","is_oa":true,"landing_page_url":"https://doi.org/10.6084/m9.figshare.4406600","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"JournalArticle"},{"id":"doi:10.6084/m9.figshare.4406600.v1","doi":"https://doi.org/10.6084/m9.figshare.4406600.v1","is_oa":true,"landing_page_url":"https://doi.org/10.6084/m9.figshare.4406600.v1","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"JournalArticle"}],"best_oa_location":{"id":"doi:10.6084/m9.figshare.4406600","doi":"https://doi.org/10.6084/m9.figshare.4406600","is_oa":true,"landing_page_url":"https://doi.org/10.6084/m9.figshare.4406600","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"JournalArticle"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9537000060081482,"id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W6921406942","https://openalex.org/W6977714964","https://openalex.org/W6939985170","https://openalex.org/W6921256694","https://openalex.org/W2512530941","https://openalex.org/W2389812258","https://openalex.org/W2311954102","https://openalex.org/W1995831059","https://openalex.org/W135902674","https://openalex.org/W2587670985"],"abstract_inverted_index":{"The":[0,35,57],"effect":[1],"of":[2,37,53,59],"oridonin":[3],"and":[4,32,39,49],"NVP-BEZ235":[5],"on":[6],"cell":[7],"cycle.":[8],"(A)":[9],"Cells":[10],"were":[11],"treated":[12],"with":[13,18,30,97],"drugs":[14],"for":[15],"48":[16],"h":[17],"the":[19,46,71,83,98],"dosages":[20],"indicated":[21],"in":[22,45],"Fig":[23],"2.":[24],"Cell":[25],"cycle":[26],"assay":[27],"was":[28,62,80],"assessed":[29],"cytometry":[31],"Modfit":[33],"LT.":[34],"percentage":[36],"G0":[38],"G1phase":[40],"cells":[41,61],"is":[42],"respectively":[43],"shown":[44],"left":[47,50],"bottom":[48],"top":[51],"corner":[52],"each":[54],"panel.":[55],"(B)":[56],"number":[58],"G0/G1":[60],"determined":[63],"using":[64,82],"quantitative":[65],"FACS":[66],"analysis.":[67],"Each":[68],"column":[69],"represents":[70],"mean":[72],"\u00b1":[73],"SD":[74],"(n":[75],"=":[76],"3).":[77],"Statistical":[78],"analysis":[79],"performed":[81],"Student\u2019s":[84],"t":[85],"test.":[86],"NS":[87],"not":[88],"significant;":[89],"*p":[90],"<":[91,94],"0.05,":[92],"**p":[93],"0.01":[95],"compared":[96],"control":[99],"group.":[100],"(PDF":[101],"295":[102],"kb)":[103]},"counts_by_year":[],"updated_date":"2026-10-28T10:33:24.094632","created_date":"2026-03-17T00:00:00"}