{"id":"https://openalex.org/W7136203152","doi":"https://doi.org/10.6084/m9.figshare.4439831","title":"Additional file 7: of ERK1 and ERK2 present functional redundancy in tetrapods despite higher evolution rate of ERK1","display_name":"Additional file 7: of ERK1 and ERK2 present functional redundancy in tetrapods despite higher evolution rate of ERK1","publication_year":2015,"publication_date":"2015-01-01","ids":{"openalex":"https://openalex.org/W7136203152","doi":"https://doi.org/10.6084/m9.figshare.4439831"},"language":"en","primary_location":{"id":"doi:10.6084/m9.figshare.4439831","doi":"https://doi.org/10.6084/m9.figshare.4439831","is_oa":true,"landing_page_url":"https://doi.org/10.6084/m9.figshare.4439831","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"JournalArticle"},"volume":null,"type":"article","indexed_in":["datacite"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://doi.org/10.6084/m9.figshare.4439831","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5000940209","display_name":"Roser Busc\u00e0","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Busc\u00e0, Roser","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009594049","display_name":"Richard Christen","orcid":"https://orcid.org/0000-0002-3396-4362","observed_orcids":["https://orcid.org/0000-0002-3396-4362"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Christen, Richard","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002105140","display_name":"Matthew B. Lovern","orcid":"https://orcid.org/0009-0008-7927-5539","observed_orcids":["https://orcid.org/0009-0008-7927-5539"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Lovern, Matthew","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065856517","display_name":"Alexander Michael Clifford","orcid":"https://orcid.org/0000-0002-2836-5832","observed_orcids":["https://orcid.org/0000-0002-2836-5832"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Clifford, Alexander","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028404995","display_name":"Jia\u2010Xing Yue","orcid":"https://orcid.org/0000-0002-2122-9221","observed_orcids":["https://orcid.org/0000-0002-2122-9221"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Yue, Jia-Xing","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5105064268","display_name":"Greg G. Goss","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Goss, Greg","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091254505","display_name":"Jacques Pouyss\u00e9gur","orcid":"https://orcid.org/0000-0003-2779-6902","observed_orcids":["https://orcid.org/0000-0003-2779-6902"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Pouyss\u00e9gur, Jacques","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5029475255","display_name":"Philippe Lenormand","orcid":"https://orcid.org/0000-0001-5326-5502","observed_orcids":["https://orcid.org/0000-0001-5326-5502"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Lenormand, Philippe","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.48658149,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11533","display_name":"Melanoma and MAPK Pathways","score":0.7035999894142151,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11533","display_name":"Melanoma and MAPK Pathways","score":0.7035999894142151,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10169","display_name":"Protein Kinase Regulation and GTPase Signaling","score":0.12080000340938568,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10268","display_name":"Developmental Biology and Gene Regulation","score":0.09589999914169312,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/erk1","display_name":"ERK1","score":0.9980000257492065},{"id":"https://openalex.org/keywords/erk2","display_name":"ERK2","score":1.0},{"id":"https://openalex.org/keywords/functional-redundancy","display_name":"functional redundancy","score":0.9390000104904175},{"id":"https://openalex.org/keywords/mapk-signaling","display_name":"MAPK signaling","score":0.8579999804496765},{"id":"https://openalex.org/keywords/cdna-sequence","display_name":"cDNA sequence","score":0.7680000066757202},{"id":"https://openalex.org/keywords/tetrapods","display_name":"tetrapods","score":0.8399999737739563},{"id":"https://openalex.org/keywords/evolutionary-rates","display_name":"evolutionary rates","score":0.5540000200271606},{"id":"https://openalex.org/keywords/biological-nomenclature","display_name":"taxonomic nomenclature","score":0.5220000147819519}],"concepts":[{"id":"https://openalex.org/C152124472","wikidata":"https://www.wikidata.org/wiki/Q1204361","display_name":"Redundancy (engineering)","level":2,"score":0.6075999736785889},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.489300012588501},{"id":"https://openalex.org/C2778961482","wikidata":"https://www.wikidata.org/wiki/Q25241","display_name":"Vertebrate","level":3,"score":0.4278999865055084},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.40860000252723694},{"id":"https://openalex.org/C58642233","wikidata":"https://www.wikidata.org/wiki/Q8269924","display_name":"Taxonomy (biology)","level":2,"score":0.3237999975681305},{"id":"https://openalex.org/C189592816","wikidata":"https://www.wikidata.org/wiki/Q427626","display_name":"Taxonomic rank","level":3,"score":0.3172000050544739},{"id":"https://openalex.org/C78458016","wikidata":"https://www.wikidata.org/wiki/Q840400","display_name":"Evolutionary biology","level":1,"score":0.3059999942779541},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.30169999599456787},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.29109999537467957},{"id":"https://openalex.org/C32795469","wikidata":"https://www.wikidata.org/wiki/Q5156430","display_name":"Complementary sequences","level":2,"score":0.2515000104904175},{"id":"https://openalex.org/C195818886","wikidata":"https://www.wikidata.org/wiki/Q5421724","display_name":"Expressive power","level":2,"score":0.2515000104904175}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.6084/m9.figshare.4439831","doi":"https://doi.org/10.6084/m9.figshare.4439831","is_oa":true,"landing_page_url":"https://doi.org/10.6084/m9.figshare.4439831","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"JournalArticle"},{"id":"doi:10.6084/m9.figshare.4439831.v1","doi":"https://doi.org/10.6084/m9.figshare.4439831.v1","is_oa":true,"landing_page_url":"https://doi.org/10.6084/m9.figshare.4439831.v1","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"JournalArticle"}],"best_oa_location":{"id":"doi:10.6084/m9.figshare.4439831","doi":"https://doi.org/10.6084/m9.figshare.4439831","is_oa":true,"landing_page_url":"https://doi.org/10.6084/m9.figshare.4439831","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"JournalArticle"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W6921099067","https://openalex.org/W6921436427","https://openalex.org/W7136891230","https://openalex.org/W6977497313","https://openalex.org/W1937411730","https://openalex.org/W7100229421","https://openalex.org/W7137150790","https://openalex.org/W6902388750","https://openalex.org/W2410865989","https://openalex.org/W1743462958"],"abstract_inverted_index":{"Animal":[0],"names":[1,65,100],"and":[2,25,63,84],"accession":[3],"numbers":[4],"of":[5,16,31,35,46,50,66,71,75,87,91,101],"erk":[6],"cDNA":[7],"sequences":[8,18,38,78],"analyzed":[9],"in":[10,20,104],"the":[11,67],"present":[12],"study.":[13],"(A)":[14],"List":[15],"vertebrate":[17],"used":[19,40,54,80,95],"Figure":[21,23,27,57,82,97],"2A,":[22],"2B":[24],"Additional":[26,56],"5A-D.":[28],"(B)":[29],"list":[30,45,70,86],"37":[32,72],"mammalian":[33,48,73,89],"pairs":[34,49,74,90],"ERKs":[36,52,76,93],"whose":[37,77],"were":[39,79],"for":[41,55,81,96],"Fig.":[42],"5.":[43],"(C)":[44],"12":[47,88],"full-length":[51,92],"sequences,":[53,94],"5E-F.":[58],"(D)":[59],"Correspondence":[60],"between":[61],"taxonomic":[62,99],"common":[64],"animals":[68,102],"studied.":[69],"S4C":[83],"D.":[85],"S7.":[98],"studied":[103],"this":[105],"work.":[106],"(PDF":[107],"2233":[108],"kb)":[109]},"counts_by_year":[],"updated_date":"2026-10-28T10:33:24.094632","created_date":"2026-03-17T00:00:00"}