{"id":"https://openalex.org/W7130650438","doi":"https://doi.org/10.1021/acs.orglett.5c05451","title":"Iron-Catalyzed Stereospecific Heterocycle N-Glycosylation with Glycal Epoxides","display_name":"Iron-Catalyzed Stereospecific Heterocycle N-Glycosylation with Glycal Epoxides","publication_year":2026,"publication_date":"2026-02-20","ids":{"openalex":"https://openalex.org/W7130650438","doi":"https://doi.org/10.1021/acs.orglett.5c05451","pmid":"https://pubmed.ncbi.nlm.nih.gov/41674818","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/12889827"},"language":"en","primary_location":{"id":"doi:10.1021/acs.orglett.5c05451","doi":"https://doi.org/10.1021/acs.orglett.5c05451","is_oa":true,"landing_page_url":"https://doi.org/10.1021/acs.orglett.5c05451","pdf_url":null,"source":{"id":"https://openalex.org/S201989124","display_name":"Organic Letters","issn_l":"1523-7052","issn":["1523-7052","1523-7060"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Organic Letters","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1021/acs.orglett.5c05451","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5050497306","display_name":"Xiao-Wen Zhang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I6902469","display_name":"Brandeis University","ror":"https://ror.org/05abbep66","country_code":"US","type":"education","lineage":["https://openalex.org/I6902469"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Xiao-Wen Zhang","raw_affiliation_strings":["Department of Chemistry, Brandeis University, 415 South Street, Waltham, Massachusetts 02453, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Brandeis University, 415 South Street, Waltham, Massachusetts 02453, United States","institution_ids":["https://openalex.org/I6902469"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5135948516","display_name":"Dakang Zhang","orcid":"https://orcid.org/0009-0005-9149-189X","observed_orcids":["https://orcid.org/0009-0005-9149-189X"]},"institutions":[{"id":"https://openalex.org/I6902469","display_name":"Brandeis University","ror":"https://ror.org/05abbep66","country_code":"US","type":"education","lineage":["https://openalex.org/I6902469"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Dakang Zhang","raw_affiliation_strings":["Department of Chemistry, Brandeis University, 415 South Street, Waltham, Massachusetts 02453, United States"],"raw_orcid":"https://orcid.org/0009-0005-9149-189X","affiliations":[{"raw_affiliation_string":"Department of Chemistry, Brandeis University, 415 South Street, Waltham, Massachusetts 02453, United States","institution_ids":["https://openalex.org/I6902469"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5121019247","display_name":"Zixiang Jiang","orcid":"https://orcid.org/0009-0007-8265-6212","observed_orcids":["https://orcid.org/0009-0007-8265-6212"]},"institutions":[{"id":"https://openalex.org/I6902469","display_name":"Brandeis University","ror":"https://ror.org/05abbep66","country_code":"US","type":"education","lineage":["https://openalex.org/I6902469"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Zixiang Jiang","raw_affiliation_strings":["Department of Chemistry, Brandeis University, 415 South Street, Waltham, Massachusetts 02453, United States"],"raw_orcid":"https://orcid.org/0009-0007-8265-6212","affiliations":[{"raw_affiliation_string":"Department of Chemistry, Brandeis University, 415 South Street, Waltham, Massachusetts 02453, United States","institution_ids":["https://openalex.org/I6902469"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5000534939","display_name":"Hao Xu","orcid":"https://orcid.org/0000-0001-5029-8392","observed_orcids":["https://orcid.org/0000-0001-5029-8392"]},"institutions":[{"id":"https://openalex.org/I6902469","display_name":"Brandeis University","ror":"https://ror.org/05abbep66","country_code":"US","type":"education","lineage":["https://openalex.org/I6902469"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Hao Xu","raw_affiliation_strings":["Department of Chemistry, Brandeis University, 415 South Street, Waltham, Massachusetts 02453, United States"],"raw_orcid":"https://orcid.org/0000-0001-5029-8392","affiliations":[{"raw_affiliation_string":"Department of Chemistry, Brandeis University, 415 South Street, Waltham, Massachusetts 02453, United States","institution_ids":["https://openalex.org/I6902469"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5000534939"],"corresponding_institution_ids":["https://openalex.org/I6902469"],"apc_list":{"value":4500,"currency":"USD","value_usd":4500},"apc_paid":{"value":4500,"currency":"USD","value_usd":4500},"fwci":4.4913,"has_fulltext":true,"cited_by_count":3,"citation_normalized_percentile":{"value":0.92303049,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":96,"max":97},"biblio":{"volume":"28","issue":"9","first_page":"2859","last_page":"2864"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10835","display_name":"Carbohydrate Chemistry and Synthesis","score":0.9726999998092651,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10835","display_name":"Carbohydrate Chemistry and Synthesis","score":0.9726999998092651,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11440","display_name":"Click Chemistry and Applications","score":0.008299999870359898,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10013","display_name":"Asymmetric Synthesis and Catalysis","score":0.004000000189989805,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/n-glycosylation","display_name":"N-glycosylation","score":0.8870000243186951},{"id":"https://openalex.org/keywords/heterocyclic-compounds","display_name":"heterocyclic compounds","score":0.8320000171661377},{"id":"https://openalex.org/keywords/iron-catalysis","display_name":"iron catalysis","score":0.9300000071525574},{"id":"https://openalex.org/keywords/stereospecific-synthesis","display_name":"stereospecific synthesis","score":0.9120000004768372},{"id":"https://openalex.org/keywords/glycosyl-donors","display_name":"glycosyl donors","score":0.5419999957084656},{"id":"https://openalex.org/keywords/functional-group-tolerance","display_name":"functional group tolerance","score":0.6669999957084656},{"id":"https://openalex.org/keywords/low-catalyst-loading","display_name":"low catalyst loading","score":0.6060000061988831}],"concepts":[{"id":"https://openalex.org/C2781259705","wikidata":"https://www.wikidata.org/wiki/Q4139724","display_name":"Glycal","level":4,"score":0.9344000220298767},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.8870999813079834},{"id":"https://openalex.org/C187921627","wikidata":"https://www.wikidata.org/wiki/Q2469470","display_name":"Stereospecificity","level":3,"score":0.8773999810218811},{"id":"https://openalex.org/C2776920199","wikidata":"https://www.wikidata.org/wiki/Q408028","display_name":"Epoxide","level":3,"score":0.7202000021934509},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.4878999888896942},{"id":"https://openalex.org/C21951064","wikidata":"https://www.wikidata.org/wiki/Q899212","display_name":"Combinatorial chemistry","level":1,"score":0.41119998693466187},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.4090000092983246},{"id":"https://openalex.org/C161790260","wikidata":"https://www.wikidata.org/wiki/Q82264","display_name":"Catalysis","level":2,"score":0.38530001044273376},{"id":"https://openalex.org/C129694887","wikidata":"https://www.wikidata.org/wiki/Q47455153","display_name":"Stereoisomerism","level":3,"score":0.3398999869823456},{"id":"https://openalex.org/C65973085","wikidata":"https://www.wikidata.org/wiki/Q888529","display_name":"Halogenation","level":2,"score":0.32760000228881836},{"id":"https://openalex.org/C124668440","wikidata":"https://www.wikidata.org/wiki/Q2305173","display_name":"Chirality (physics)","level":5,"score":0.2827000021934509}],"mesh":[],"locations_count":7,"locations":[{"id":"doi:10.1021/acs.orglett.5c05451","doi":"https://doi.org/10.1021/acs.orglett.5c05451","is_oa":true,"landing_page_url":"https://doi.org/10.1021/acs.orglett.5c05451","pdf_url":null,"source":{"id":"https://openalex.org/S201989124","display_name":"Organic Letters","issn_l":"1523-7052","issn":["1523-7052","1523-7060"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Organic Letters","raw_type":"journal-article"},{"id":"doi:10.21203/rs.3.rs-8650471/v1","doi":"https://doi.org/10.21203/rs.3.rs-8650471/v1","is_oa":true,"landing_page_url":"https://doi.org/10.21203/rs.3.rs-8650471/v1","pdf_url":"https://www.researchsquare.com/article/rs-8650471/latest.pdf","source":{"id":"https://openalex.org/S4306525896","display_name":"Research Square","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Research Square","raw_type":"posted-content"},{"id":"pmh:oai:pubmedcentral.nih.gov:12949690","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12949690/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12949690/pdf/ol5c05451.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Org Lett","raw_type":"Text"},{"id":"pmid:41674818","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/41674818","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Research square","raw_type":"Journal Article"},{"id":"pmid:41715894","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/41715894","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Organic letters","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:12889827","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12889827/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Res Sq","raw_type":"Text"},{"id":"pmh:oai:europepmc.org:11697268","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/12889827","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1021/acs.orglett.5c05451","doi":"https://doi.org/10.1021/acs.orglett.5c05451","is_oa":true,"landing_page_url":"https://doi.org/10.1021/acs.orglett.5c05451","pdf_url":null,"source":{"id":"https://openalex.org/S201989124","display_name":"Organic Letters","issn_l":"1523-7052","issn":["1523-7052","1523-7060"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Organic Letters","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G4980010018","display_name":"A 400 MHz NMR Spectrometer","funder_award_id":"1s10od034395-01","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G9000906674","display_name":"Selective Nitrogen Atom Transfer for Applications in Biomedical Sciences","funder_award_id":"R35GM134926","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7130650438.pdf","grobid_xml":"https://content.openalex.org/works/W7130650438.grobid-xml"},"referenced_works_count":49,"referenced_works":["https://openalex.org/W1931117181","https://openalex.org/W1966166244","https://openalex.org/W1978072572","https://openalex.org/W1982301628","https://openalex.org/W1983361540","https://openalex.org/W2002180270","https://openalex.org/W2018402216","https://openalex.org/W2020964576","https://openalex.org/W2046485205","https://openalex.org/W2051745789","https://openalex.org/W2067100972","https://openalex.org/W2074135835","https://openalex.org/W2085162280","https://openalex.org/W2090868139","https://openalex.org/W2090928998","https://openalex.org/W2106227497","https://openalex.org/W2108071482","https://openalex.org/W2113605084","https://openalex.org/W2145690291","https://openalex.org/W2159190877","https://openalex.org/W2326903983","https://openalex.org/W2327948152","https://openalex.org/W2508183632","https://openalex.org/W2950071697","https://openalex.org/W2950091501","https://openalex.org/W2951470196","https://openalex.org/W3002286621","https://openalex.org/W3037355974","https://openalex.org/W3062184722","https://openalex.org/W3135170410","https://openalex.org/W4200165974","https://openalex.org/W4214908515","https://openalex.org/W4235239922","https://openalex.org/W4310600821","https://openalex.org/W4311673967","https://openalex.org/W4313909778","https://openalex.org/W4387674463","https://openalex.org/W4391659489","https://openalex.org/W4392356874","https://openalex.org/W4392799805","https://openalex.org/W4394999798","https://openalex.org/W4399359286","https://openalex.org/W4401352315","https://openalex.org/W4404699132","https://openalex.org/W4407802774","https://openalex.org/W4411926713","https://openalex.org/W4414666986","https://openalex.org/W4414779933","https://openalex.org/W7116751986"],"related_works":["https://openalex.org/W4414779933","https://openalex.org/W7155188884","https://openalex.org/W2755859323","https://openalex.org/W4401352315","https://openalex.org/W4394999798","https://openalex.org/W7163128831","https://openalex.org/W4404840303","https://openalex.org/W7168377599","https://openalex.org/W7206194671","https://openalex.org/W7214082175"],"abstract_inverted_index":{"Stereospecific":[0],"N-glycosylation":[1,18,37],"of":[2,60],"heterocycles":[3],"with":[4,19,46],"glycal":[5,22,41,63],"epoxides":[6,42,64],"could":[7],"readily":[8],"provide":[9],"valuable":[10],"building":[11],"blocks":[12],"for":[13,39,56],"drug":[14],"discovery,":[15],"but":[16],"heterocycle":[17,36],"a":[20,57],"pyranose-based":[21],"epoxide":[23],"is":[24,52],"still":[25],"difficult":[26],"using":[27],"existing":[28],"methods.":[29],"We":[30],"report":[31],"herein":[32],"an":[33],"iron-catalyzed":[34],"stereospecific":[35],"method":[38,51],"these":[40],"in":[43],"high":[44],"yields":[45],"low":[47],"catalyst":[48],"loadings.":[49],"This":[50],"functional-group-tolerant":[53],"and":[54,65],"effective":[55],"wide":[58],"variety":[59],"functionalized,":[61],"complex":[62],"heterocycles.":[66]},"counts_by_year":[{"year":2026,"cited_by_count":3}],"updated_date":"2026-11-09T13:22:03.289127","created_date":"2026-02-20T00:00:00"}
