{"id":"https://openalex.org/W7128406975","doi":"https://doi.org/10.1016/j.jphotobiol.2026.113386","title":"Photosensitization activity of normal and Hyperporphyirins self-assembled with recombinant albumin: Consequences for the development of engineered photoreceptor proteins","display_name":"Photosensitization activity of normal and Hyperporphyirins self-assembled with recombinant albumin: Consequences for the development of engineered photoreceptor proteins","publication_year":2026,"publication_date":"2026-02-07","ids":{"openalex":"https://openalex.org/W7128406975","doi":"https://doi.org/10.1016/j.jphotobiol.2026.113386","pmid":"https://pubmed.ncbi.nlm.nih.gov/41671773"},"language":"en","primary_location":{"id":"doi:10.1016/j.jphotobiol.2026.113386","doi":"https://doi.org/10.1016/j.jphotobiol.2026.113386","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.jphotobiol.2026.113386","pdf_url":null,"source":{"id":"https://openalex.org/S148303206","display_name":"Journal of Photochemistry and Photobiology B Biology","issn_l":"1011-1344","issn":["1011-1344","1873-2682"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Photochemistry and Photobiology B: Biology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5087105990","display_name":"Omar J. Castillo","orcid":"https://orcid.org/0000-0001-6956-4646","observed_orcids":["https://orcid.org/0000-0001-6956-4646"]},"institutions":[{"id":"https://openalex.org/I45438204","display_name":"The University of Texas at San Antonio","ror":"https://ror.org/01kd65564","country_code":"US","type":"education","lineage":["https://openalex.org/I45438204"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Omar Castillo","raw_affiliation_strings":["Department of Physics and Astronomy, University of Texas at San Antonio, San Antonio, TX, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physics and Astronomy, University of Texas at San Antonio, San Antonio, TX, USA","institution_ids":["https://openalex.org/I45438204"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5094166302","display_name":"Lydia Martinez Rivera","orcid":"https://orcid.org/0009-0004-8527-2044","observed_orcids":["https://orcid.org/0009-0004-8527-2044"]},"institutions":[{"id":"https://openalex.org/I45438204","display_name":"The University of Texas at San Antonio","ror":"https://ror.org/01kd65564","country_code":"US","type":"education","lineage":["https://openalex.org/I45438204"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lydia Martinez Rivera","raw_affiliation_strings":["Department of Physics and Astronomy, University of Texas at San Antonio, San Antonio, TX, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physics and Astronomy, University of Texas at San Antonio, San Antonio, TX, USA","institution_ids":["https://openalex.org/I45438204"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108915661","display_name":"Abdullah Albalawi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I45438204","display_name":"The University of Texas at San Antonio","ror":"https://ror.org/01kd65564","country_code":"US","type":"education","lineage":["https://openalex.org/I45438204"]},{"id":"https://openalex.org/I72264486","display_name":"University of Tabuk","ror":"https://ror.org/04yej8x59","country_code":"SA","type":"education","lineage":["https://openalex.org/I72264486"]}],"countries":["SA","US"],"is_corresponding":false,"raw_author_name":"Abdullah Albalawi","raw_affiliation_strings":["Department of Physics and Astronomy, University of Texas at San Antonio, San Antonio, TX, USA; Physics Department, Faculty of Science, University of Tabuk, Tabuk, Saudi Arabia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physics and Astronomy, University of Texas at San Antonio, San Antonio, TX, USA; Physics Department, Faculty of Science, University of Tabuk, Tabuk, Saudi Arabia","institution_ids":["https://openalex.org/I45438204","https://openalex.org/I72264486"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5037534302","display_name":"Lorenzo Brancaleon","orcid":"https://orcid.org/0000-0003-1039-339X","observed_orcids":["https://orcid.org/0000-0003-1039-339X"]},"institutions":[{"id":"https://openalex.org/I45438204","display_name":"The University of Texas at San Antonio","ror":"https://ror.org/01kd65564","country_code":"US","type":"education","lineage":["https://openalex.org/I45438204"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Lorenzo Brancaleon","raw_affiliation_strings":["Department of Physics and Astronomy, University of Texas at San Antonio, San Antonio, TX, USA. Electronic address: lorenzo.brancaleon@utsa.edu"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physics and Astronomy, University of Texas at San Antonio, San Antonio, TX, USA. Electronic address: lorenzo.brancaleon@utsa.edu","institution_ids":["https://openalex.org/I45438204"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5037534302"],"corresponding_institution_ids":["https://openalex.org/I45438204"],"apc_list":{"value":4110,"currency":"USD","value_usd":4110},"apc_paid":null,"fwci":4.6982,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.90154155,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":93,"max":96},"biblio":{"volume":"276","issue":null,"first_page":"113386","last_page":"113386"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10957","display_name":"Photodynamic Therapy Research Studies","score":0.8925999999046326,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10957","display_name":"Photodynamic Therapy Research Studies","score":0.8925999999046326,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10903","display_name":"Porphyrin and Phthalocyanine Chemistry","score":0.0966000035405159,"subfield":{"id":"https://openalex.org/subfields/2505","display_name":"Materials Chemistry"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12441","display_name":"Porphyrin Metabolism and Disorders","score":0.007600000128149986,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/photosensitization","display_name":"photosensitization","score":0.8889999985694885},{"id":"https://openalex.org/keywords/porphyrins","display_name":"porphyrins","score":0.9340000152587891},{"id":"https://openalex.org/keywords/recombinant-human-serum-albumin","display_name":"recombinant human serum albumin","score":0.9290000200271606},{"id":"https://openalex.org/keywords/photoproducts","display_name":"photoproducts","score":0.7570000290870667},{"id":"https://openalex.org/keywords/porphyrin-fluorescence","display_name":"porphyrin fluorescence","score":0.652999997138977},{"id":"https://openalex.org/keywords/photosensitizers","display_name":"photosensitizers","score":0.4819999933242798}],"concepts":[{"id":"https://openalex.org/C2777723881","wikidata":"https://www.wikidata.org/wiki/Q107315604","display_name":"Hemin","level":4,"score":0.88919997215271},{"id":"https://openalex.org/C31332276","wikidata":"https://www.wikidata.org/wiki/Q899750","display_name":"Photobleaching","level":3,"score":0.8046000003814697},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.7728999853134155},{"id":"https://openalex.org/C40767141","wikidata":"https://www.wikidata.org/wiki/Q285697","display_name":"Recombinant DNA","level":3,"score":0.717199981212616},{"id":"https://openalex.org/C2777516457","wikidata":"https://www.wikidata.org/wiki/Q2413613","display_name":"Singlet oxygen","level":3,"score":0.7010999917984009},{"id":"https://openalex.org/C2779671804","wikidata":"https://www.wikidata.org/wiki/Q619815","display_name":"Protoporphyrin IX","level":3,"score":0.6245999932289124},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.5859000086784363},{"id":"https://openalex.org/C2778417259","wikidata":"https://www.wikidata.org/wiki/Q619815","display_name":"Protoporphyrin","level":3,"score":0.5202000141143799},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.459199994802475},{"id":"https://openalex.org/C75473681","wikidata":"https://www.wikidata.org/wiki/Q188651","display_name":"Photochemistry","level":1,"score":0.43369999527931213},{"id":"https://openalex.org/C2779480358","wikidata":"https://www.wikidata.org/wiki/Q422926","display_name":"Porphyrin","level":2,"score":0.43130001425743103},{"id":"https://openalex.org/C2781323092","wikidata":"https://www.wikidata.org/wiki/Q1428072","display_name":"Photodynamic therapy","level":2,"score":0.4163999855518341},{"id":"https://openalex.org/C166940927","wikidata":"https://www.wikidata.org/wiki/Q178827","display_name":"Monomer","level":3,"score":0.39969998598098755},{"id":"https://openalex.org/C91881484","wikidata":"https://www.wikidata.org/wiki/Q191807","display_name":"Fluorescence","level":2,"score":0.3864000141620636},{"id":"https://openalex.org/C20639190","wikidata":"https://www.wikidata.org/wiki/Q2088972","display_name":"Phototoxicity","level":3,"score":0.3785000145435333},{"id":"https://openalex.org/C184651966","wikidata":"https://www.wikidata.org/wiki/Q906356","display_name":"Aqueous solution","level":2,"score":0.37529999017715454},{"id":"https://openalex.org/C86807702","wikidata":"https://www.wikidata.org/wiki/Q2620381","display_name":"Bovine serum albumin","level":2,"score":0.3650999963283539},{"id":"https://openalex.org/C2778597219","wikidata":"https://www.wikidata.org/wiki/Q11721976","display_name":"Human serum albumin","level":2,"score":0.3555000126361847},{"id":"https://openalex.org/C2781469039","wikidata":"https://www.wikidata.org/wiki/Q18388377","display_name":"Photosensitizer","level":2,"score":0.3481999933719635},{"id":"https://openalex.org/C51639874","wikidata":"https://www.wikidata.org/wiki/Q167149","display_name":"Plasma protein binding","level":2,"score":0.3467000126838684},{"id":"https://openalex.org/C48349386","wikidata":"https://www.wikidata.org/wiki/Q424361","display_name":"Reactive oxygen species","level":2,"score":0.32109999656677246},{"id":"https://openalex.org/C75079739","wikidata":"https://www.wikidata.org/wiki/Q1571801","display_name":"Intramolecular force","level":2,"score":0.3075999915599823},{"id":"https://openalex.org/C147816474","wikidata":"https://www.wikidata.org/wiki/Q169525","display_name":"Protein engineering","level":3,"score":0.3073999881744385},{"id":"https://openalex.org/C20705724","wikidata":"https://www.wikidata.org/wiki/Q902628","display_name":"Hemeprotein","level":4,"score":0.2955000102519989},{"id":"https://openalex.org/C26659971","wikidata":"https://www.wikidata.org/wiki/Q729923","display_name":"Fluorescence recovery after photobleaching","level":3,"score":0.28790000081062317},{"id":"https://openalex.org/C47701112","wikidata":"https://www.wikidata.org/wiki/Q735188","display_name":"Protein structure","level":2,"score":0.2806999981403351},{"id":"https://openalex.org/C16318435","wikidata":"https://www.wikidata.org/wiki/Q149299","display_name":"Mutagenesis","level":4,"score":0.2784000039100647},{"id":"https://openalex.org/C123669783","wikidata":"https://www.wikidata.org/wiki/Q902898","display_name":"Electron transfer","level":2,"score":0.27410000562667847},{"id":"https://openalex.org/C2776253728","wikidata":"https://www.wikidata.org/wiki/Q422964","display_name":"Biliverdin","level":5,"score":0.27160000801086426},{"id":"https://openalex.org/C544153396","wikidata":"https://www.wikidata.org/wiki/Q11426","display_name":"Metal","level":2,"score":0.2669000029563904},{"id":"https://openalex.org/C188198153","wikidata":"https://www.wikidata.org/wiki/Q1613840","display_name":"Limiting","level":2,"score":0.25920000672340393}],"mesh":[{"descriptor_ui":"D006427","descriptor_name":"Hemin","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008027","descriptor_name":"Light","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011166","descriptor_name":"Porphyrins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D011524","descriptor_name":"Protoporphyrins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D011524","descriptor_name":"Protoporphyrins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D011994","descriptor_name":"Recombinant Proteins","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D011994","descriptor_name":"Recombinant Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D011994","descriptor_name":"Recombinant Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011994","descriptor_name":"Recombinant Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D012709","descriptor_name":"Serum Albumin","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D012709","descriptor_name":"Serum Albumin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D012709","descriptor_name":"Serum Albumin","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D015202","descriptor_name":"Protein Engineering","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017319","descriptor_name":"Photosensitizing Agents","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D026082","descriptor_name":"Singlet Oxygen","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D026082","descriptor_name":"Singlet Oxygen","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.jphotobiol.2026.113386","doi":"https://doi.org/10.1016/j.jphotobiol.2026.113386","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.jphotobiol.2026.113386","pdf_url":null,"source":{"id":"https://openalex.org/S148303206","display_name":"Journal of Photochemistry and Photobiology B Biology","issn_l":"1011-1344","issn":["1011-1344","1873-2682"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Photochemistry and Photobiology B: Biology","raw_type":"journal-article"},{"id":"pmid:41671773","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/41671773","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of photochemistry and photobiology. B, Biology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320335743","display_name":"Saudi Arabian Cultural Mission","ror":"https://ror.org/01wa3dz59"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":73,"referenced_works":["https://openalex.org/W104036075","https://openalex.org/W1536155243","https://openalex.org/W1631638135","https://openalex.org/W1964200863","https://openalex.org/W1965187409","https://openalex.org/W1966746445","https://openalex.org/W1970905152","https://openalex.org/W1975586699","https://openalex.org/W1978342126","https://openalex.org/W1985384717","https://openalex.org/W1988490804","https://openalex.org/W1990970138","https://openalex.org/W2008748363","https://openalex.org/W2014745838","https://openalex.org/W2027259280","https://openalex.org/W2028689547","https://openalex.org/W2036187452","https://openalex.org/W2046971384","https://openalex.org/W2051974238","https://openalex.org/W2057350586","https://openalex.org/W2060483715","https://openalex.org/W2062261789","https://openalex.org/W2063038066","https://openalex.org/W2069464126","https://openalex.org/W2070501442","https://openalex.org/W2075017779","https://openalex.org/W2078398728","https://openalex.org/W2082877358","https://openalex.org/W2085093588","https://openalex.org/W2085161549","https://openalex.org/W2090012540","https://openalex.org/W2091448564","https://openalex.org/W2102697716","https://openalex.org/W2108474129","https://openalex.org/W2120347046","https://openalex.org/W2126588926","https://openalex.org/W2130056527","https://openalex.org/W2135031492","https://openalex.org/W2135362034","https://openalex.org/W2136698583","https://openalex.org/W2147520936","https://openalex.org/W2150240082","https://openalex.org/W2157812356","https://openalex.org/W2169936405","https://openalex.org/W2237011222","https://openalex.org/W2238155968","https://openalex.org/W2317286799","https://openalex.org/W2317873538","https://openalex.org/W2322705052","https://openalex.org/W2331494093","https://openalex.org/W2573958740","https://openalex.org/W2592943758","https://openalex.org/W2594551536","https://openalex.org/W2613169589","https://openalex.org/W2793258669","https://openalex.org/W2800110311","https://openalex.org/W2944793306","https://openalex.org/W2975620807","https://openalex.org/W2991343954","https://openalex.org/W2997636241","https://openalex.org/W3127329048","https://openalex.org/W3165785156","https://openalex.org/W3182706339","https://openalex.org/W4210456256","https://openalex.org/W4236397303","https://openalex.org/W4283733510","https://openalex.org/W4293359975","https://openalex.org/W4308038417","https://openalex.org/W4389203394","https://openalex.org/W4402343051","https://openalex.org/W4402343880","https://openalex.org/W4408499071","https://openalex.org/W4409726348"],"related_works":["https://openalex.org/W1974069718","https://openalex.org/W2005497061","https://openalex.org/W989113771","https://openalex.org/W7214757247","https://openalex.org/W2039204758","https://openalex.org/W4291269132","https://openalex.org/W2044151606","https://openalex.org/W4319721575","https://openalex.org/W2002782041","https://openalex.org/W7099016096"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2026-02-10T00:00:00"}