{"id":"https://openalex.org/W7128385341","doi":"https://doi.org/10.1016/j.amjcard.2026.01.016","title":"Radial Versus Femoral Secondary Access in Patients Undergoing TAVI: Rationale and Design of the RADIAL-TAVI Trial","display_name":"Radial Versus Femoral Secondary Access in Patients Undergoing TAVI: Rationale and Design of the RADIAL-TAVI Trial","publication_year":2026,"publication_date":"2026-02-07","ids":{"openalex":"https://openalex.org/W7128385341","doi":"https://doi.org/10.1016/j.amjcard.2026.01.016","pmid":"https://pubmed.ncbi.nlm.nih.gov/41663046"},"language":"en","primary_location":{"id":"doi:10.1016/j.amjcard.2026.01.016","doi":"https://doi.org/10.1016/j.amjcard.2026.01.016","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.amjcard.2026.01.016","pdf_url":null,"source":{"id":"https://openalex.org/S185186944","display_name":"The American Journal of Cardiology","issn_l":"0002-9149","issn":["0002-9149","1879-1913"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American Journal of Cardiology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1016/j.amjcard.2026.01.016","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5074292874","display_name":"Alexander von Ehr","orcid":"https://orcid.org/0000-0003-0849-321X","observed_orcids":["https://orcid.org/0000-0003-0849-321X"]},"institutions":[{"id":"https://openalex.org/I161046081","display_name":"University of Freiburg","ror":"https://ror.org/0245cg223","country_code":"DE","type":"education","lineage":["https://openalex.org/I161046081"]},{"id":"https://openalex.org/I4210133302","display_name":"Universit\u00e4ts-Herzzentrum Freiburg-Bad Krozingen","ror":"https://ror.org/02w6m7e50","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I2801240073","https://openalex.org/I4210133302"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Alexander von Ehr","raw_affiliation_strings":["Department of Cardiology and Angiology, University Heart Center Freiburg-Bad Krozingen, Faculty of Medicine, University of Freiburg, Freiburg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology and Angiology, University Heart Center Freiburg-Bad Krozingen, Faculty of Medicine, University of Freiburg, Freiburg, Germany","institution_ids":["https://openalex.org/I161046081","https://openalex.org/I4210133302"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085798844","display_name":"Uwe Zeymer","orcid":"https://orcid.org/0000-0001-7077-283X","observed_orcids":["https://orcid.org/0000-0001-7077-283X"]},"institutions":[{"id":"https://openalex.org/I161046081","display_name":"University of Freiburg","ror":"https://ror.org/0245cg223","country_code":"DE","type":"education","lineage":["https://openalex.org/I161046081"]},{"id":"https://openalex.org/I4210133302","display_name":"Universit\u00e4ts-Herzzentrum Freiburg-Bad Krozingen","ror":"https://ror.org/02w6m7e50","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I2801240073","https://openalex.org/I4210133302"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Uwe Zeymer","raw_affiliation_strings":["Department of Cardiology and Angiology, University Heart Center Freiburg-Bad Krozingen, Faculty of Medicine, University of Freiburg, Freiburg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology and Angiology, University Heart Center Freiburg-Bad Krozingen, Faculty of Medicine, University of Freiburg, Freiburg, Germany","institution_ids":["https://openalex.org/I161046081","https://openalex.org/I4210133302"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101524054","display_name":"Steffen Schneider","orcid":"https://orcid.org/0000-0003-3256-0726","observed_orcids":["https://orcid.org/0000-0003-3256-0726","https://orcid.org/0000-0001-9375-4861"]},"institutions":[{"id":"https://openalex.org/I4210114639","display_name":"Stiftung Institut f\u00fcr Herzinfarktforschung","ror":"https://ror.org/0213d4b59","country_code":"DE","type":"other","lineage":["https://openalex.org/I4210114639"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Steffen Schneider","raw_affiliation_strings":["Institut f\u00fcr Herzinfarktforschung, Ludwigshafen am Rhein, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut f\u00fcr Herzinfarktforschung, Ludwigshafen am Rhein, Germany","institution_ids":["https://openalex.org/I4210114639"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049481596","display_name":"Christian Besler","orcid":"https://orcid.org/0000-0002-8082-6472","observed_orcids":["https://orcid.org/0000-0002-8082-6472"]},"institutions":[{"id":"https://openalex.org/I161046081","display_name":"University of Freiburg","ror":"https://ror.org/0245cg223","country_code":"DE","type":"education","lineage":["https://openalex.org/I161046081"]},{"id":"https://openalex.org/I4210133302","display_name":"Universit\u00e4ts-Herzzentrum Freiburg-Bad Krozingen","ror":"https://ror.org/02w6m7e50","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I2801240073","https://openalex.org/I4210133302"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Christian Besler","raw_affiliation_strings":["Department of Cardiology and Angiology, University Heart Center Freiburg-Bad Krozingen, Faculty of Medicine, University of Freiburg, Freiburg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology and Angiology, University Heart Center Freiburg-Bad Krozingen, Faculty of Medicine, University of Freiburg, Freiburg, Germany","institution_ids":["https://openalex.org/I161046081","https://openalex.org/I4210133302"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070103202","display_name":"Christian Valina","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I161046081","display_name":"University of Freiburg","ror":"https://ror.org/0245cg223","country_code":"DE","type":"education","lineage":["https://openalex.org/I161046081"]},{"id":"https://openalex.org/I4210133302","display_name":"Universit\u00e4ts-Herzzentrum Freiburg-Bad Krozingen","ror":"https://ror.org/02w6m7e50","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I2801240073","https://openalex.org/I4210133302"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Christian Valina","raw_affiliation_strings":["Department of Cardiology and Angiology, University Heart Center Freiburg-Bad Krozingen, Faculty of Medicine, University of Freiburg, Freiburg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology and Angiology, University Heart Center Freiburg-Bad Krozingen, Faculty of Medicine, University of Freiburg, Freiburg, Germany","institution_ids":["https://openalex.org/I161046081","https://openalex.org/I4210133302"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069680685","display_name":"Moritz Seiffert","orcid":"https://orcid.org/0000-0002-3940-9079","observed_orcids":["https://orcid.org/0000-0002-3940-9079"]},"institutions":[{"id":"https://openalex.org/I4210139845","display_name":"BG University Hospital Bergmannsheil Bochum","ror":"https://ror.org/04j9bvy88","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I2799784675","https://openalex.org/I4210139845"]},{"id":"https://openalex.org/I904495901","display_name":"Ruhr University Bochum","ror":"https://ror.org/04tsk2644","country_code":"DE","type":"education","lineage":["https://openalex.org/I904495901"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Moritz Seiffert","raw_affiliation_strings":["Department of Cardiology and Angiology, BG University Hospital Bergmannsheil, Ruhr-University Bochum, Bochum, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology and Angiology, BG University Hospital Bergmannsheil, Ruhr-University Bochum, Bochum, Germany","institution_ids":["https://openalex.org/I4210139845","https://openalex.org/I904495901"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029674394","display_name":"Felix Mahfoud","orcid":"https://orcid.org/0000-0002-4425-549X","observed_orcids":["https://orcid.org/0000-0002-4425-549X"]},"institutions":[{"id":"https://openalex.org/I1850255","display_name":"University of Basel","ror":"https://ror.org/02s6k3f65","country_code":"CH","type":"education","lineage":["https://openalex.org/I1850255"]},{"id":"https://openalex.org/I2802542264","display_name":"University Hospital of Basel","ror":"https://ror.org/04k51q396","country_code":"CH","type":"healthcare","lineage":["https://openalex.org/I2802542264"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Felix Mahfoud","raw_affiliation_strings":["Department of Cardiology, Biomedical Engineering and Biomedicine, University Heart Center, University Hospital Basel, Basel, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology, Biomedical Engineering and Biomedicine, University Heart Center, University Hospital Basel, Basel, Switzerland","institution_ids":["https://openalex.org/I1850255","https://openalex.org/I2802542264"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020872201","display_name":"Samuel Tobias Sossalla","orcid":"https://orcid.org/0000-0001-8034-2673","observed_orcids":["https://orcid.org/0000-0001-8034-2673"]},"institutions":[{"id":"https://openalex.org/I200763008","display_name":"Justus-Liebig-Universit\u00e4t Gie\u00dfen","ror":"https://ror.org/033eqas34","country_code":"DE","type":"education","lineage":["https://openalex.org/I200763008"]},{"id":"https://openalex.org/I4210127591","display_name":"German Centre for Cardiovascular Research","ror":"https://ror.org/031t5w623","country_code":"DE","type":"facility","lineage":["https://openalex.org/I4210127591","https://openalex.org/I4405256427"]},{"id":"https://openalex.org/I4210133626","display_name":"Kerckhoff Klinik","ror":"https://ror.org/04m54m956","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210133626"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Samuel Sossalla","raw_affiliation_strings":["Department of Cardiology, Campus Kerckhoff of the Justus-Liebig-University Giessen, Kerckhoff-Klinik, Bad Nauheim, Germany; German Center for Cardiovascular Research (DZHK), Partner Site Rhine-Main, Bad Nauheim, Germany; Department of Cardiology and Angiology, Medical Clinic I, University Hospital Giessen, Justus-Liebig-University Giessen, Giessen, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology, Campus Kerckhoff of the Justus-Liebig-University Giessen, Kerckhoff-Klinik, Bad Nauheim, Germany; German Center for Cardiovascular Research (DZHK), Partner Site Rhine-Main, Bad Nauheim, Germany; Department of Cardiology and Angiology, Medical Clinic I, University Hospital Giessen, Justus-Liebig-University Giessen, Giessen, Germany","institution_ids":["https://openalex.org/I200763008","https://openalex.org/I4210127591","https://openalex.org/I4210133626"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046594613","display_name":"Ingo Hilgendorf","orcid":"https://orcid.org/0000-0002-0024-1643","observed_orcids":["https://orcid.org/0000-0002-0024-1643"]},"institutions":[{"id":"https://openalex.org/I161046081","display_name":"University of Freiburg","ror":"https://ror.org/0245cg223","country_code":"DE","type":"education","lineage":["https://openalex.org/I161046081"]},{"id":"https://openalex.org/I4210105663","display_name":"Deutsches Herzzentrum der Charit\u00e9","ror":"https://ror.org/01mmady97","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210105663","https://openalex.org/I7877124"]},{"id":"https://openalex.org/I4210127591","display_name":"German Centre for Cardiovascular Research","ror":"https://ror.org/031t5w623","country_code":"DE","type":"facility","lineage":["https://openalex.org/I4210127591","https://openalex.org/I4405256427"]},{"id":"https://openalex.org/I4210133302","display_name":"Universit\u00e4ts-Herzzentrum Freiburg-Bad Krozingen","ror":"https://ror.org/02w6m7e50","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I2801240073","https://openalex.org/I4210133302"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Ingo Hilgendorf","raw_affiliation_strings":["Department of Cardiology and Angiology, University Heart Center Freiburg-Bad Krozingen, Faculty of Medicine, University of Freiburg, Freiburg, Germany; DZHK (German Centre for Cardiovascular Research), Berlin, Germany; Department of Cardiology, Angiology and Intensive Care Medicine, Deutsches Herzzentrum der Charit\u00e9 (DHZC), Campus Virchow Klinikum, Berlin, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology and Angiology, University Heart Center Freiburg-Bad Krozingen, Faculty of Medicine, University of Freiburg, Freiburg, Germany; DZHK (German Centre for Cardiovascular Research), Berlin, Germany; Department of Cardiology, Angiology and Intensive Care Medicine, Deutsches Herzzentrum der Charit\u00e9 (DHZC), Campus Virchow Klinikum, Berlin, Germany","institution_ids":["https://openalex.org/I161046081","https://openalex.org/I4210105663","https://openalex.org/I4210127591","https://openalex.org/I4210133302"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006337265","display_name":"Dennis M. Wolf","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I161046081","display_name":"University of Freiburg","ror":"https://ror.org/0245cg223","country_code":"DE","type":"education","lineage":["https://openalex.org/I161046081"]},{"id":"https://openalex.org/I4210133302","display_name":"Universit\u00e4ts-Herzzentrum Freiburg-Bad Krozingen","ror":"https://ror.org/02w6m7e50","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I2801240073","https://openalex.org/I4210133302"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Dennis Wolf","raw_affiliation_strings":["Department of Cardiology and Angiology, University Heart Center Freiburg-Bad Krozingen, Faculty of Medicine, University of Freiburg, Freiburg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology and Angiology, University Heart Center Freiburg-Bad Krozingen, Faculty of Medicine, University of Freiburg, Freiburg, Germany","institution_ids":["https://openalex.org/I161046081","https://openalex.org/I4210133302"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073384141","display_name":"Martin A. Moser","orcid":"https://orcid.org/0000-0003-4919-2587","observed_orcids":["https://orcid.org/0000-0003-4919-2587"]},"institutions":[{"id":"https://openalex.org/I161046081","display_name":"University of Freiburg","ror":"https://ror.org/0245cg223","country_code":"DE","type":"education","lineage":["https://openalex.org/I161046081"]},{"id":"https://openalex.org/I4210133302","display_name":"Universit\u00e4ts-Herzzentrum Freiburg-Bad Krozingen","ror":"https://ror.org/02w6m7e50","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I2801240073","https://openalex.org/I4210133302"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Martin Moser","raw_affiliation_strings":["Department of Cardiology and Angiology, University Heart Center Freiburg-Bad Krozingen, Faculty of Medicine, University of Freiburg, Freiburg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology and Angiology, University Heart Center Freiburg-Bad Krozingen, Faculty of Medicine, University of Freiburg, Freiburg, Germany","institution_ids":["https://openalex.org/I161046081","https://openalex.org/I4210133302"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5116157878","display_name":"Leonie Ziegler","orcid":"https://orcid.org/0009-0004-1117-5137","observed_orcids":["https://orcid.org/0009-0004-1117-5137"]},"institutions":[{"id":"https://openalex.org/I161046081","display_name":"University of Freiburg","ror":"https://ror.org/0245cg223","country_code":"DE","type":"education","lineage":["https://openalex.org/I161046081"]},{"id":"https://openalex.org/I4210133302","display_name":"Universit\u00e4ts-Herzzentrum Freiburg-Bad Krozingen","ror":"https://ror.org/02w6m7e50","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I2801240073","https://openalex.org/I4210133302"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Leonie Ziegler","raw_affiliation_strings":["Department of Cardiology and Angiology, University Heart Center Freiburg-Bad Krozingen, Faculty of Medicine, University of Freiburg, Freiburg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology and Angiology, University Heart Center Freiburg-Bad Krozingen, Faculty of Medicine, University of Freiburg, Freiburg, Germany","institution_ids":["https://openalex.org/I161046081","https://openalex.org/I4210133302"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5125422585","display_name":"Malte Niehoff","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I161046081","display_name":"University of Freiburg","ror":"https://ror.org/0245cg223","country_code":"DE","type":"education","lineage":["https://openalex.org/I161046081"]},{"id":"https://openalex.org/I4210133302","display_name":"Universit\u00e4ts-Herzzentrum Freiburg-Bad Krozingen","ror":"https://ror.org/02w6m7e50","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I2801240073","https://openalex.org/I4210133302"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Malte Niehoff","raw_affiliation_strings":["Department of Cardiology and Angiology, University Heart Center Freiburg-Bad Krozingen, Faculty of Medicine, University of Freiburg, Freiburg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology and Angiology, University Heart Center Freiburg-Bad Krozingen, Faculty of Medicine, University of Freiburg, Freiburg, Germany","institution_ids":["https://openalex.org/I161046081","https://openalex.org/I4210133302"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061070510","display_name":"Christoph B. Olivier","orcid":"https://orcid.org/0000-0002-3065-625X","observed_orcids":["https://orcid.org/0000-0002-3065-625X"]},"institutions":[{"id":"https://openalex.org/I161046081","display_name":"University of Freiburg","ror":"https://ror.org/0245cg223","country_code":"DE","type":"education","lineage":["https://openalex.org/I161046081"]},{"id":"https://openalex.org/I4210133302","display_name":"Universit\u00e4ts-Herzzentrum Freiburg-Bad Krozingen","ror":"https://ror.org/02w6m7e50","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I2801240073","https://openalex.org/I4210133302"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Christoph B. Olivier","raw_affiliation_strings":["Department of Cardiology and Angiology, University Heart Center Freiburg-Bad Krozingen, Faculty of Medicine, University of Freiburg, Freiburg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology and Angiology, University Heart Center Freiburg-Bad Krozingen, Faculty of Medicine, University of Freiburg, Freiburg, Germany","institution_ids":["https://openalex.org/I161046081","https://openalex.org/I4210133302"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050868282","display_name":"Dirk Westermann","orcid":"https://orcid.org/0000-0002-7542-1956","observed_orcids":["https://orcid.org/0000-0002-7542-1956"]},"institutions":[{"id":"https://openalex.org/I161046081","display_name":"University of Freiburg","ror":"https://ror.org/0245cg223","country_code":"DE","type":"education","lineage":["https://openalex.org/I161046081"]},{"id":"https://openalex.org/I4210133302","display_name":"Universit\u00e4ts-Herzzentrum Freiburg-Bad Krozingen","ror":"https://ror.org/02w6m7e50","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I2801240073","https://openalex.org/I4210133302"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Dirk Westermann","raw_affiliation_strings":["Department of Cardiology and Angiology, University Heart Center Freiburg-Bad Krozingen, Faculty of Medicine, University of Freiburg, Freiburg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology and Angiology, University Heart Center Freiburg-Bad Krozingen, Faculty of Medicine, University of Freiburg, Freiburg, Germany","institution_ids":["https://openalex.org/I161046081","https://openalex.org/I4210133302"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5058725388","display_name":"Constantin von zur M\u00fchlen","orcid":"https://orcid.org/0000-0003-2767-8009","observed_orcids":["https://orcid.org/0000-0003-2767-8009"]},"institutions":[{"id":"https://openalex.org/I161046081","display_name":"University of Freiburg","ror":"https://ror.org/0245cg223","country_code":"DE","type":"education","lineage":["https://openalex.org/I161046081"]},{"id":"https://openalex.org/I4210133302","display_name":"Universit\u00e4ts-Herzzentrum Freiburg-Bad Krozingen","ror":"https://ror.org/02w6m7e50","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I2801240073","https://openalex.org/I4210133302"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"Constantin von zur M\u00fchlen","raw_affiliation_strings":["Department of Cardiology and Angiology, University Heart Center Freiburg-Bad Krozingen, Faculty of Medicine, University of Freiburg, Freiburg, Germany. Electronic address: constantin.vonzurmuehlen@uniklinik-freiburg.de"],"raw_orcid":"https://orcid.org/0000-0003-2767-8009","affiliations":[{"raw_affiliation_string":"Department of Cardiology and Angiology, University Heart Center Freiburg-Bad Krozingen, Faculty of Medicine, University of Freiburg, Freiburg, Germany. Electronic address: constantin.vonzurmuehlen@uniklinik-freiburg.de","institution_ids":["https://openalex.org/I161046081","https://openalex.org/I4210133302"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":11,"corresponding_author_ids":["https://openalex.org/A5058725388"],"corresponding_institution_ids":["https://openalex.org/I161046081","https://openalex.org/I4210133302"],"apc_list":{"value":3380,"currency":"USD","value_usd":3380},"apc_paid":{"value":3380,"currency":"USD","value_usd":3380},"fwci":3.6083,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.86054498,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":91,"max":95},"biblio":{"volume":"265","issue":null,"first_page":"27","last_page":"31"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11554","display_name":"Vascular Procedures and Complications","score":0.5292999744415283,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11554","display_name":"Vascular Procedures and Complications","score":0.5292999744415283,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10172","display_name":"Cardiac Valve Diseases and Treatments","score":0.45190000534057617,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10618","display_name":"Aortic Disease and Treatment Approaches","score":0.00430000014603138,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/transcatheter-aortic-valve-replacement","display_name":"transcatheter aortic valve implantation","score":0.9879999756813049},{"id":"https://openalex.org/keywords/transradial-access","display_name":"transradial access","score":0.8059999942779541},{"id":"https://openalex.org/keywords/femoral-access","display_name":"transfemoral access","score":0.9800000190734863},{"id":"https://openalex.org/keywords/vascular-complications","display_name":"vascular complications","score":0.7730000019073486},{"id":"https://openalex.org/keywords/bleeding-complications","display_name":"bleeding complications","score":0.9919999837875366},{"id":"https://openalex.org/keywords/severe-aortic-stenosis","display_name":"severe aortic stenosis","score":0.8920000195503235},{"id":"https://openalex.org/keywords/varc-3-criteria","display_name":"VARC-3 criteria","score":0.8159999847412109},{"id":"https://openalex.org/keywords/major-adverse-cardiac-and-cerebrovascular-events","display_name":"major adverse cardiac and cerebrovascular events","score":0.8159999847412109},{"id":"https://openalex.org/keywords/health-economics","display_name":"health economics","score":0.4050000011920929}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9412000179290771},{"id":"https://openalex.org/C203092338","wikidata":"https://www.wikidata.org/wiki/Q1340863","display_name":"Clinical endpoint","level":3,"score":0.7402999997138977},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.625},{"id":"https://openalex.org/C2780007028","wikidata":"https://www.wikidata.org/wiki/Q2343082","display_name":"Stenosis","level":2,"score":0.6007999777793884},{"id":"https://openalex.org/C168563851","wikidata":"https://www.wikidata.org/wiki/Q1436668","display_name":"Randomized controlled trial","level":2,"score":0.531499981880188},{"id":"https://openalex.org/C2778218979","wikidata":"https://www.wikidata.org/wiki/Q662857","display_name":"Radial artery","level":3,"score":0.5148000121116638},{"id":"https://openalex.org/C23131810","wikidata":"https://www.wikidata.org/wiki/Q818574","display_name":"Observational study","level":2,"score":0.5091999769210815},{"id":"https://openalex.org/C2779723990","wikidata":"https://www.wikidata.org/wiki/Q707174","display_name":"Femoral artery","level":2,"score":0.5083000063896179},{"id":"https://openalex.org/C81182388","wikidata":"https://www.wikidata.org/wiki/Q353963","display_name":"Complication","level":2,"score":0.45399999618530273},{"id":"https://openalex.org/C197934379","wikidata":"https://www.wikidata.org/wiki/Q2047938","display_name":"Adverse effect","level":2,"score":0.45170000195503235},{"id":"https://openalex.org/C61511704","wikidata":"https://www.wikidata.org/wiki/Q1671857","display_name":"Incidence (geometry)","level":2,"score":0.43369999527931213},{"id":"https://openalex.org/C2781414266","wikidata":"https://www.wikidata.org/wiki/Q531019","display_name":"Aortic valve stenosis","level":3,"score":0.3822999894618988},{"id":"https://openalex.org/C2776570981","wikidata":"https://www.wikidata.org/wiki/Q4413093","display_name":"Aortic valve replacement","level":3,"score":0.34549999237060547},{"id":"https://openalex.org/C3019417119","wikidata":"https://www.wikidata.org/wiki/Q1773974","display_name":"Secondary prevention","level":2,"score":0.335099995136261},{"id":"https://openalex.org/C2780643987","wikidata":"https://www.wikidata.org/wiki/Q468414","display_name":"Angiography","level":2,"score":0.31690001487731934},{"id":"https://openalex.org/C535046627","wikidata":"https://www.wikidata.org/wiki/Q30612","display_name":"Clinical trial","level":2,"score":0.30489999055862427},{"id":"https://openalex.org/C2776016174","wikidata":"https://www.wikidata.org/wiki/Q28502965","display_name":"Vascular access","level":3,"score":0.289000004529953},{"id":"https://openalex.org/C2780026749","wikidata":"https://www.wikidata.org/wiki/Q7912830","display_name":"Valve replacement","level":3,"score":0.2678000032901764},{"id":"https://openalex.org/C3017811039","wikidata":"https://www.wikidata.org/wiki/Q166019","display_name":"Major bleeding","level":3,"score":0.25279998779296875}],"mesh":[{"descriptor_ui":"D001024","descriptor_name":"Aortic Valve Stenosis","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":true},{"descriptor_ui":"D005263","descriptor_name":"Femoral Artery","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011183","descriptor_name":"Postoperative Complications","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017534","descriptor_name":"Radial Artery","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D065467","descriptor_name":"Transcatheter Aortic Valve Replacement","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1016/j.amjcard.2026.01.016","doi":"https://doi.org/10.1016/j.amjcard.2026.01.016","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.amjcard.2026.01.016","pdf_url":null,"source":{"id":"https://openalex.org/S185186944","display_name":"The American Journal of Cardiology","issn_l":"0002-9149","issn":["0002-9149","1879-1913"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American Journal of Cardiology","raw_type":"journal-article"},{"id":"pmid:41663046","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/41663046","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American journal of cardiology","raw_type":"Journal Article"},{"id":"pmh:oai:freidok.uni-freiburg.de:277139","doi":null,"is_oa":false,"landing_page_url":"https://freidok.uni-freiburg.de/data/277139","pdf_url":null,"source":{"id":"https://openalex.org/S4306401057","display_name":"FreiDok plus (Universit\u00e4tsbibliothek Freiburg)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I161046081","host_organization_name":"University of Freiburg","host_organization_lineage":["https://openalex.org/I161046081"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"The American journal of cardiology. - 265 (2026) , 27-31, ISSN: 1879-1913","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1016/j.amjcard.2026.01.016","doi":"https://doi.org/10.1016/j.amjcard.2026.01.016","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.amjcard.2026.01.016","pdf_url":null,"source":{"id":"https://openalex.org/S185186944","display_name":"The American Journal of Cardiology","issn_l":"0002-9149","issn":["0002-9149","1879-1913"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American Journal of Cardiology","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9940000176429749,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Study Protocol","id":"https://openalex.org/study-designs/study-protocol"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":16,"referenced_works":["https://openalex.org/W41242259","https://openalex.org/W432037510","https://openalex.org/W2033376206","https://openalex.org/W2119943845","https://openalex.org/W2149609916","https://openalex.org/W2162937051","https://openalex.org/W2166973706","https://openalex.org/W2171941310","https://openalex.org/W2324073140","https://openalex.org/W2596188051","https://openalex.org/W2625889445","https://openalex.org/W3101796377","https://openalex.org/W3156869543","https://openalex.org/W3195842247","https://openalex.org/W4386153206","https://openalex.org/W4405762459"],"related_works":["https://openalex.org/W7135051406","https://openalex.org/W2131746653","https://openalex.org/W3037656734","https://openalex.org/W3214204189","https://openalex.org/W3110150282","https://openalex.org/W4412531635","https://openalex.org/W2066417472","https://openalex.org/W3008227072","https://openalex.org/W4403843025","https://openalex.org/W2790236358"],"abstract_inverted_index":{"Transcatheter":[0],"aortic":[1,15],"valve":[2],"implantation":[3],"(TAVI)":[4],"has":[5,220],"become":[6],"the":[7,41,121,129,184,201,206,221],"standard":[8,225],"treatment":[9],"for":[10,48],"patients":[11,101,109],"with":[12,60,189,193],"severe":[13],"symptomatic":[14],"stenosis":[16],"(AS)":[17],"across":[18],"most":[19,45],"surgical":[20],"risk":[21],"categories.":[22],"Despite":[23],"its":[24],"minimally":[25],"invasive":[26],"nature,":[27],"transfemoral":[28,103,212],"TAVI":[29,66],"requires":[30],"both":[31],"a":[32,35,85,114,181],"primary":[33,118,185],"and":[34,52,57,125,151,158,230,234],"secondary":[36,49,71,98,130,208],"arterial":[37],"access":[38,72,99,131,209,216],"site.":[39],"While":[40],"femoral":[42,79,97,190],"artery":[43],"is":[44,84,120,177],"commonly":[46],"used":[47],"access,":[50],"vascular":[51,124],"bleeding":[53,126],"complications":[54,76,127],"remain":[55],"frequent":[56],"are":[58],"associated":[59],"adverse":[61,149],"outcomes.":[62,235],"Observational":[63],"evidence":[64,204],"from":[65,187],"cohorts":[67],"suggests":[68],"that":[69],"radial":[70,95,194,215],"may":[73],"reduce":[74,227],"such":[75],"compared":[77],"to":[78,93,138,163,172,179,191,223],"access.":[80,195],"The":[81,117,175,196],"RADIAL-TAVI":[82,197],"trial":[83,198],"prospective,":[86],"randomized,":[87],"controlled,":[88],"multicenter,":[89],"open-label":[90],"study":[91,176],"designed":[92],"compare":[94],"versus":[96],"in":[100,113,183,211],"undergoing":[102],"TAVI.":[104,213],"A":[105],"total":[106],"of":[107,123,156],"434":[108],"will":[110,199],"be":[111],"randomized":[112,203],"1:1":[115],"ratio.":[116],"endpoint":[119,186],"incidence":[122],"at":[128],"site":[132],"within":[133],"30":[134,164],"days,":[135,165],"adjudicated":[136],"according":[137],"VARC-3":[139],"criteria.":[140],"Secondary":[141],"endpoints":[142],"include":[143],"early":[144],"safety,":[145],"cardiovascular":[146,150],"mortality,":[147],"major":[148],"cerebrovascular":[152],"events":[153],"(MACCE),":[154],"quality":[155],"life,":[157],"health":[159],"economic":[160],"aspects":[161],"up":[162,171],"as":[166,168],"well":[167],"long-term":[169],"mortality":[170],"12":[173],"months.":[174],"powered":[178],"detect":[180],"reduction":[182],"8%":[188],"2%":[192],"provide":[200],"first":[202],"on":[205],"optimal":[207],"strategy":[210],"If":[214],"proves":[217],"superior,":[218],"it":[219],"potential":[222],"redefine":[224],"practice,":[226],"complication":[228],"rates,":[229],"improve":[231],"patient":[232],"safety":[233]},"counts_by_year":[{"year":2026,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2026-02-10T00:00:00"}