{"id":"https://openalex.org/W7128360921","doi":"https://doi.org/10.1002/epd2.70199","title":"Electrophysiological patterns and therapeutic outcomes in DEE \u2010 SWAS : A cohort study from a tertiary pediatric neurology center","display_name":"Electrophysiological patterns and therapeutic outcomes in DEE \u2010 SWAS : A cohort study from a tertiary pediatric neurology center","publication_year":2026,"publication_date":"2026-02-09","ids":{"openalex":"https://openalex.org/W7128360921","doi":"https://doi.org/10.1002/epd2.70199","pmid":"https://pubmed.ncbi.nlm.nih.gov/41661091"},"language":"en","primary_location":{"id":"doi:10.1002/epd2.70199","doi":"https://doi.org/10.1002/epd2.70199","is_oa":true,"landing_page_url":"https://doi.org/10.1002/epd2.70199","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/epd2.70199","source":{"id":"https://openalex.org/S82373125","display_name":"Epileptic Disorders","issn_l":"1294-9361","issn":["1294-9361","1950-6945"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Epileptic Disorders","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/epd2.70199","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5082339862","display_name":"Fatma Hanc\u0131","orcid":"https://orcid.org/0000-0002-1019-9207","observed_orcids":["https://orcid.org/0000-0002-1019-9207"]},"institutions":[{"id":"https://openalex.org/I4387152860","display_name":"Trabzon University","ror":"https://ror.org/04mmwq306","country_code":null,"type":"education","lineage":["https://openalex.org/I4387152860"]}],"countries":[],"is_corresponding":true,"raw_author_name":"Fatma Hanci","raw_affiliation_strings":["Division of Child Neurology, Department of Pediatrics Kanuni Education and Training Hospital, Trabzon University Medical School  Trabzon Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Child Neurology, Department of Pediatrics Kanuni Education and Training Hospital, Trabzon University Medical School  Trabzon Turkey","institution_ids":["https://openalex.org/I4387152860"]}]},{"author_position":"last","author":{"id":null,"display_name":"Ay\u015feg\u00fcl Dani\u015f","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I76973811","display_name":"Bolu Abant \u0130zzet Baysal University","ror":"https://ror.org/01x1kqx83","country_code":"TR","type":"education","lineage":["https://openalex.org/I76973811"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Ay\u015feg\u00fcl Dani\u015f","raw_affiliation_strings":["Division of Child Neurology, Department of Pediatrics Bolu Izzet Baysal Education and Training Hospital, Abant Izzet Baysal University  Bolu Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Child Neurology, Department of Pediatrics Bolu Izzet Baysal Education and Training Hospital, Abant Izzet Baysal University  Bolu Turkey","institution_ids":["https://openalex.org/I76973811"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5082339862"],"corresponding_institution_ids":["https://openalex.org/I4387152860"],"apc_list":{"value":2430,"currency":"USD","value_usd":2430},"apc_paid":null,"fwci":4.6213,"has_fulltext":true,"cited_by_count":1,"citation_normalized_percentile":{"value":0.89895544,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":96},"biblio":{"volume":"28","issue":"3","first_page":"799","last_page":"808"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10094","display_name":"Epilepsy research and treatment","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10094","display_name":"Epilepsy research and treatment","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13201","display_name":"Infectious Encephalopathies and Encephalitis","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12229","display_name":"Pharmacological Effects and Toxicity Studies","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/developmental-and-epileptic-encephalopathy","display_name":"developmental and epileptic encephalopathy","score":0.9279999732971191},{"id":"https://openalex.org/keywords/spike-wave-index","display_name":"spike-wave index","score":0.8529999852180481},{"id":"https://openalex.org/keywords/prognosis","display_name":"prognosis","score":0.5080000162124634},{"id":"https://openalex.org/keywords/eeg-background-activity","display_name":"EEG background activity","score":0.7799999713897705},{"id":"https://openalex.org/keywords/eeg-abnormalities","display_name":"EEG abnormalities","score":0.34200000762939453},{"id":"https://openalex.org/keywords/pediatric-epilepsy","display_name":"pediatric epilepsy","score":0.5230000019073486},{"id":"https://openalex.org/keywords/prognostic-factors","display_name":"prognostic factors","score":0.6150000095367432}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8312000036239624},{"id":"https://openalex.org/C16568411","wikidata":"https://www.wikidata.org/wiki/Q83042","display_name":"Neurology","level":2,"score":0.6970999836921692},{"id":"https://openalex.org/C201903717","wikidata":"https://www.wikidata.org/wiki/Q1778788","display_name":"Cohort study","level":2,"score":0.5475999712944031},{"id":"https://openalex.org/C2779746230","wikidata":"https://www.wikidata.org/wiki/Q15752159","display_name":"Pediatric Neurology","level":2,"score":0.546500027179718},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.5221999883651733},{"id":"https://openalex.org/C72563966","wikidata":"https://www.wikidata.org/wiki/Q1303415","display_name":"Cohort","level":2,"score":0.4986000061035156},{"id":"https://openalex.org/C58693492","wikidata":"https://www.wikidata.org/wiki/Q551875","display_name":"Neuroimaging","level":2,"score":0.48590001463890076},{"id":"https://openalex.org/C522805319","wikidata":"https://www.wikidata.org/wiki/Q179965","display_name":"Electroencephalography","level":2,"score":0.4691999852657318},{"id":"https://openalex.org/C2779463800","wikidata":"https://www.wikidata.org/wiki/Q5062222","display_name":"Center (category theory)","level":2,"score":0.42329999804496765},{"id":"https://openalex.org/C2779889316","wikidata":"https://www.wikidata.org/wiki/Q642836","display_name":"Neuroradiology","level":3,"score":0.40070000290870667},{"id":"https://openalex.org/C116834253","wikidata":"https://www.wikidata.org/wiki/Q2039217","display_name":"Identification (biology)","level":2,"score":0.39480000734329224},{"id":"https://openalex.org/C167135981","wikidata":"https://www.wikidata.org/wiki/Q2146302","display_name":"Retrospective cohort study","level":2,"score":0.3874000012874603},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.3361999988555908},{"id":"https://openalex.org/C2780073493","wikidata":"https://www.wikidata.org/wiki/Q7523837","display_name":"Single Center","level":2,"score":0.33219999074935913},{"id":"https://openalex.org/C185263204","wikidata":"https://www.wikidata.org/wiki/Q1154774","display_name":"Electrophysiology","level":2,"score":0.32030001282691956},{"id":"https://openalex.org/C2779473830","wikidata":"https://www.wikidata.org/wiki/Q1540899","display_name":"MEDLINE","level":2,"score":0.2944999933242798},{"id":"https://openalex.org/C194828623","wikidata":"https://www.wikidata.org/wiki/Q2861470","display_name":"Emergency medicine","level":1,"score":0.29170000553131104},{"id":"https://openalex.org/C205545832","wikidata":"https://www.wikidata.org/wiki/Q17156455","display_name":"Young adult","level":2,"score":0.27709999680519104},{"id":"https://openalex.org/C2992435398","wikidata":"https://www.wikidata.org/wiki/Q6934595","display_name":"Multicenter study","level":3,"score":0.2727000117301941},{"id":"https://openalex.org/C2991842025","wikidata":"https://www.wikidata.org/wiki/Q31207","display_name":"Tertiary care","level":2,"score":0.2712000012397766},{"id":"https://openalex.org/C2778186239","wikidata":"https://www.wikidata.org/wiki/Q41571","display_name":"Epilepsy","level":2,"score":0.265500009059906},{"id":"https://openalex.org/C188816634","wikidata":"https://www.wikidata.org/wiki/Q2113324","display_name":"Prospective cohort study","level":2,"score":0.25540000200271606},{"id":"https://openalex.org/C2780317758","wikidata":"https://www.wikidata.org/wiki/Q3339235","display_name":"Neurological disorder","level":3,"score":0.25209999084472656}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002675","descriptor_name":"Child, Preschool","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004569","descriptor_name":"Electroencephalography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004827","descriptor_name":"Epilepsy","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012890","descriptor_name":"Sleep","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D015331","descriptor_name":"Cohort Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D062606","descriptor_name":"Tertiary Care Centers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1002/epd2.70199","doi":"https://doi.org/10.1002/epd2.70199","is_oa":true,"landing_page_url":"https://doi.org/10.1002/epd2.70199","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/epd2.70199","source":{"id":"https://openalex.org/S82373125","display_name":"Epileptic Disorders","issn_l":"1294-9361","issn":["1294-9361","1950-6945"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Epileptic Disorders","raw_type":"journal-article"},{"id":"pmid:41661091","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/41661091","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Epileptic disorders : international epilepsy journal with videotape","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1002/epd2.70199","doi":"https://doi.org/10.1002/epd2.70199","is_oa":true,"landing_page_url":"https://doi.org/10.1002/epd2.70199","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/epd2.70199","source":{"id":"https://openalex.org/S82373125","display_name":"Epileptic Disorders","issn_l":"1294-9361","issn":["1294-9361","1950-6945"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Epileptic Disorders","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/3","score":0.413705050945282,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7128360921.pdf","grobid_xml":"https://content.openalex.org/works/W7128360921.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":[],"abstract_inverted_index":{"OBJECTIVE:":[0],"This":[1],"study":[2],"aimed":[3],"to":[4,28,119],"evaluate":[5],"the":[6,122,178,217,230],"clinical,":[7],"electrophysiological,":[8],"and":[9,18,27,44,64,69,108,138,146,159,167,188,201,225],"radiological":[10],"characteristics":[11],"of":[12,47,50,97,104,180,210,219,222,232],"pediatric":[13,36],"patients":[14,37,105,153,224],"diagnosed":[15],"with":[16,21,32,38,72,90,126,177,195],"developmental":[17],"epileptic":[19],"encephalopathy":[20],"spike-wave":[22,40],"activation":[23],"during":[24,162],"sleep":[25],"(DEE-SWAS)":[26],"identify":[29],"factors":[30],"associated":[31,176,194],"prognosis.":[33,197],"METHODS:":[34],"Twenty-five":[35],"a":[39,45,91],"index":[41],"(SWI)":[42],"\u226550%":[43],"minimum":[46],"2":[48],"years":[49],"follow-up":[51],"were":[52,67,106,110],"analyzed":[53],"in":[54,191,229],"this":[55],"retrospective":[56],"cohort":[57],"study.":[58],"Clinical":[59],"data,":[60],"electroencephalogram":[61],"(EEG)":[62],"findings,":[63],"neuroimaging":[65],"results":[66],"assessed,":[68],"their":[70],"relationship":[71],"residual":[73,127,181],"neurological":[74,172,212],"or":[75],"electrophysiological":[76],"abnormalities":[77],"was":[78,85,116,174],"examined.":[79],"RESULTS:":[80],"The":[81,112],"patients'":[82],"mean":[83,92,114],"age":[84,93],"9.4":[86],"\u00b1":[87,99],"2.97":[88],"years,":[89],"at":[94,134],"seizure":[95],"onset":[96],"6.6":[98],"2.32":[100],"years.":[101],"Etiologically,":[102],"60%":[103],"unknown,":[107],"40%":[109],"known.":[111],"baseline":[113],"SWI":[115,132,192,200],"67.1%,":[117],"decreasing":[118],"13.8%":[120],"by":[121],"24th":[123],"month.":[124],"Patients":[125],"findings":[128,182,215],"had":[129],"significantly":[130,175],"higher":[131,160],"values":[133],"months":[135],"3,":[136],"6,":[137],"24":[139],"(p":[140,164,183],"=":[141,144,148,165,169,184],".04,":[142],"p":[143,147,168],".006,":[145],".01,":[149],"respectively).":[150],"Additionally,":[151],"these":[152],"exhibited":[154],"lower":[155],"EEG":[156,204],"background":[157,203],"frequency":[158],"amplitude":[161],"wakefulness":[163],".026":[166],".001).":[170],"Abnormal":[171],"examination":[173],"presence":[179],".02).":[185],"SIGNIFICANCE:":[186],"Early":[187],"substantial":[189],"reduction":[190],"is":[193],"better":[196],"Persistent":[198],"high":[199],"abnormal":[202],"activity":[205],"may":[206],"serve":[207],"as":[208],"predictors":[209],"long-term":[211],"impairment.":[213],"These":[214],"underscored":[216],"importance":[218],"early":[220],"identification":[221],"high-risk":[223],"personalized":[226],"treatment":[227],"strategies":[228],"management":[231],"DEE-SWAS.":[233]},"counts_by_year":[{"year":2026,"cited_by_count":1}],"updated_date":"2026-10-12T09:40:04.860316","created_date":"2026-02-10T00:00:00"}