{"id":"https://openalex.org/W7127973383","doi":"https://doi.org/10.15406/aovs.2026.16.00499","title":"Unveiling the uncommon: a case report on primary Neisseria meningitidis keratitis","display_name":"Unveiling the uncommon: a case report on primary Neisseria meningitidis keratitis","publication_year":2026,"publication_date":"2026-01-12","ids":{"openalex":"https://openalex.org/W7127973383","doi":"https://doi.org/10.15406/aovs.2026.16.00499"},"language":"en","primary_location":{"id":"doi:10.15406/aovs.2026.16.00499","doi":"https://doi.org/10.15406/aovs.2026.16.00499","is_oa":true,"landing_page_url":"https://doi.org/10.15406/aovs.2026.16.00499","pdf_url":"https://medcraveonline.com/AOVS/AOVS-16-00499.pdf","source":{"id":"https://openalex.org/S2765076038","display_name":"Advances in Ophthalmology & Visual System","issn_l":"2377-4290","issn":["2377-4290"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310320093","host_organization_name":"MedCrave Group","host_organization_lineage":["https://openalex.org/P4310320093"],"host_organization_lineage_names":["MedCrave Group"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Advances in Ophthalmology & Visual System","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://medcraveonline.com/AOVS/AOVS-16-00499.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5087019520","display_name":"Fatima Alalawi","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Fatima Alalawi","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5125229823","display_name":"Latifa Alalawi","orcid":"https://orcid.org/0009-0001-7049-0573","observed_orcids":["https://orcid.org/0009-0001-7049-0573"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Latifa Alalawi","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5125154645","display_name":"Nidal Hassan","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Nidal Hassan","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075417685","display_name":"Ahmed Alsaadi","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ahmed AlSaadi","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5004728590","display_name":"Amna Almaazmi","orcid":"https://orcid.org/0009-0001-8251-0367","observed_orcids":["https://orcid.org/0009-0001-8251-0367"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Amna AlMaazmi","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0009-0001-8251-0367","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.05976876,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"16","issue":"1","first_page":"5","last_page":"7"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11826","display_name":"Ocular Infections and Treatments","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11826","display_name":"Ocular Infections and Treatments","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10873","display_name":"Bacterial Infections and Vaccines","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11867","display_name":"Traumatic Ocular and Foreign Body Injuries","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/neisseria-meningitidis","display_name":"Neisseria meningitidis","score":0.9520000219345093},{"id":"https://openalex.org/keywords/contact-lens-wearers","display_name":"contact lens wearers","score":0.7599999904632568},{"id":"https://openalex.org/keywords/myopia","display_name":"myopia","score":0.6489999890327454},{"id":"https://openalex.org/keywords/misdiagnosis","display_name":"misdiagnosis","score":0.8500000238418579},{"id":"https://openalex.org/keywords/superficial-keratectomy","display_name":"superficial keratectomy","score":0.9440000057220459},{"id":"https://openalex.org/keywords/ceftriaxone","display_name":"ceftriaxone","score":0.8379999995231628},{"id":"https://openalex.org/keywords/chlorhexidine","display_name":"chlorhexidine","score":0.7670000195503235},{"id":"https://openalex.org/keywords/corneal-epithelial-defects","display_name":"corneal epithelial defects","score":0.781000018119812},{"id":"https://openalex.org/keywords/ocular-surface-disease","display_name":"ocular surface disease","score":0.4449999928474426}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9132000207901001},{"id":"https://openalex.org/C2778458888","wikidata":"https://www.wikidata.org/wiki/Q154625","display_name":"Neisseria meningitidis","level":3,"score":0.7713000178337097},{"id":"https://openalex.org/C2780576314","wikidata":"https://www.wikidata.org/wiki/Q922971","display_name":"Acanthamoeba keratitis","level":3,"score":0.7317000031471252},{"id":"https://openalex.org/C2778836808","wikidata":"https://www.wikidata.org/wiki/Q424940","display_name":"Moxifloxacin","level":3,"score":0.7113999724388123},{"id":"https://openalex.org/C2779513239","wikidata":"https://www.wikidata.org/wiki/Q3510332","display_name":"Corneal abrasion","level":3,"score":0.6460000276565552},{"id":"https://openalex.org/C2778560704","wikidata":"https://www.wikidata.org/wiki/Q757838","display_name":"Keratitis","level":2,"score":0.6315000057220459},{"id":"https://openalex.org/C16005928","wikidata":"https://www.wikidata.org/wiki/Q171171","display_name":"Dermatology","level":1,"score":0.6047999858856201},{"id":"https://openalex.org/C2986805488","wikidata":"https://www.wikidata.org/wiki/Q23797","display_name":"Contact lens","level":2,"score":0.5911999940872192},{"id":"https://openalex.org/C2778868110","wikidata":"https://www.wikidata.org/wiki/Q1152218","display_name":"Acanthamoeba","level":2,"score":0.4708000123500824},{"id":"https://openalex.org/C2780608754","wikidata":"https://www.wikidata.org/wiki/Q5171111","display_name":"Corneal perforation","level":3,"score":0.421099990606308},{"id":"https://openalex.org/C2781403741","wikidata":"https://www.wikidata.org/wiki/Q1638140","display_name":"Hypopyon","level":3,"score":0.4162999987602234},{"id":"https://openalex.org/C2776645655","wikidata":"https://www.wikidata.org/wiki/Q890785","display_name":"Meningococcal disease","level":4,"score":0.38659998774528503},{"id":"https://openalex.org/C2908692415","wikidata":"https://www.wikidata.org/wiki/Q167844","display_name":"Bacterial Conjunctivitis","level":3,"score":0.3840000033378601},{"id":"https://openalex.org/C2781413609","wikidata":"https://www.wikidata.org/wiki/Q7308373","display_name":"Regimen","level":2,"score":0.38280001282691956},{"id":"https://openalex.org/C2777084678","wikidata":"https://www.wikidata.org/wiki/Q15646788","display_name":"Chlorhexidine","level":2,"score":0.3785000145435333},{"id":"https://openalex.org/C205501099","wikidata":"https://www.wikidata.org/wiki/Q188990","display_name":"Gram staining","level":3,"score":0.3653999865055084},{"id":"https://openalex.org/C118487528","wikidata":"https://www.wikidata.org/wiki/Q161437","display_name":"Ophthalmology","level":1,"score":0.36410000920295715},{"id":"https://openalex.org/C2781253189","wikidata":"https://www.wikidata.org/wiki/Q221179","display_name":"Streptococcus pneumoniae","level":3,"score":0.3621000051498413},{"id":"https://openalex.org/C501593827","wikidata":"https://www.wikidata.org/wiki/Q12187","display_name":"Antibiotics","level":2,"score":0.36169999837875366},{"id":"https://openalex.org/C2776882836","wikidata":"https://www.wikidata.org/wiki/Q168291","display_name":"Cornea","level":2,"score":0.3587999939918518},{"id":"https://openalex.org/C2776520383","wikidata":"https://www.wikidata.org/wiki/Q421713","display_name":"Ceftriaxone","level":3,"score":0.34790000319480896},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.34549999237060547},{"id":"https://openalex.org/C2776148792","wikidata":"https://www.wikidata.org/wiki/Q3041498","display_name":"Eye disease","level":2,"score":0.32420000433921814},{"id":"https://openalex.org/C2776702029","wikidata":"https://www.wikidata.org/wiki/Q1628473","display_name":"corneal ulcer","level":3,"score":0.2915000021457672},{"id":"https://openalex.org/C2777235844","wikidata":"https://www.wikidata.org/wiki/Q1294912","display_name":"Endophthalmitis","level":2,"score":0.2863999903202057},{"id":"https://openalex.org/C3019796121","wikidata":"https://www.wikidata.org/wiki/Q5048356","display_name":"Case presentation","level":2,"score":0.2782999873161316},{"id":"https://openalex.org/C174802600","wikidata":"https://www.wikidata.org/wiki/Q12190","display_name":"Penicillin","level":3,"score":0.27810001373291016},{"id":"https://openalex.org/C206179267","wikidata":"https://www.wikidata.org/wiki/Q188952","display_name":"Medical history","level":2,"score":0.27799999713897705},{"id":"https://openalex.org/C2910275740","wikidata":"https://www.wikidata.org/wiki/Q1628473","display_name":"Corneal ulceration","level":3,"score":0.26100000739097595}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.15406/aovs.2026.16.00499","doi":"https://doi.org/10.15406/aovs.2026.16.00499","is_oa":true,"landing_page_url":"https://doi.org/10.15406/aovs.2026.16.00499","pdf_url":"https://medcraveonline.com/AOVS/AOVS-16-00499.pdf","source":{"id":"https://openalex.org/S2765076038","display_name":"Advances in Ophthalmology & Visual System","issn_l":"2377-4290","issn":["2377-4290"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310320093","host_organization_name":"MedCrave Group","host_organization_lineage":["https://openalex.org/P4310320093"],"host_organization_lineage_names":["MedCrave Group"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Advances in Ophthalmology & Visual System","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.15406/aovs.2026.16.00499","doi":"https://doi.org/10.15406/aovs.2026.16.00499","is_oa":true,"landing_page_url":"https://doi.org/10.15406/aovs.2026.16.00499","pdf_url":"https://medcraveonline.com/AOVS/AOVS-16-00499.pdf","source":{"id":"https://openalex.org/S2765076038","display_name":"Advances in Ophthalmology & Visual System","issn_l":"2377-4290","issn":["2377-4290"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310320093","host_organization_name":"MedCrave Group","host_organization_lineage":["https://openalex.org/P4310320093"],"host_organization_lineage_names":["MedCrave Group"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Advances in Ophthalmology & Visual System","raw_type":"journal-article"},"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/case-report","display_name":"Case Report"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7127973383.pdf","grobid_xml":"https://content.openalex.org/works/W7127973383.grobid-xml"},"referenced_works_count":12,"referenced_works":["https://openalex.org/W1989687013","https://openalex.org/W2001473391","https://openalex.org/W2048890115","https://openalex.org/W2150182483","https://openalex.org/W2161634119","https://openalex.org/W2604848170","https://openalex.org/W2940079106","https://openalex.org/W2981427009","https://openalex.org/W3165196979","https://openalex.org/W4319297883","https://openalex.org/W4361268334","https://openalex.org/W4387807445"],"related_works":["https://openalex.org/W7163653212","https://openalex.org/W2327115742","https://openalex.org/W2001473391","https://openalex.org/W4378348666","https://openalex.org/W1989687013","https://openalex.org/W1853698166","https://openalex.org/W2161634119","https://openalex.org/W2333683660","https://openalex.org/W4410103727","https://openalex.org/W2772481463"],"abstract_inverted_index":{"Purpose:":[0],"To":[1],"report":[2,25,45,176],"an":[3,47,178],"atypical":[4,179],"case":[5,24,44,175],"of":[6,29,35,59,77,87,144,170,181,201,230,238],"primary":[7,36,184],"meningococcal":[8,37],"keratitis":[9,187],"in":[10,228],"a":[11,42,69,138,190,214,223],"myopic":[12],"contact":[13,50,209],"lens":[14,51,210],"wearer,":[15,52],"with":[16,55,141,189,213],"typical":[17],"clinical":[18,85],"features":[19],"resembling":[20],"acanthamoeba":[21,88],"keratitis.":[22,38],"This":[23,40,174],"emphasizes":[26],"the":[27,75,83,90,128,164,199,205,232],"significance":[28],"early":[30],"diagnosis,":[31],"investigations,":[32],"and":[33,63,72,106,115,121,137,235,247,252],"management":[34],"Case-report:":[39],"is":[41,243],"single-patient":[43],"describing":[46],"18-year-old":[48],"male,":[49],"who":[53],"presented":[54],"1":[56],"month":[57],"history":[58],"left":[60],"eye":[61],"redness,":[62],"discomfort.":[64],"His":[65],"initial":[66,84,165],"exam":[67],"showed":[68],"semi-ring-shaped":[70],"infiltrate,":[71,216],"cultures":[73],"confirmed":[74,130,183],"presence":[76],"Neisseria":[78],"meningitidis.":[79],"Results:":[80],"Based":[81],"on":[82,167],"suspicion":[86],"keratitis,":[89],"patient":[91],"was":[92,99,135,151],"managed":[93],"by":[94],"total":[95],"superficial":[96],"keratectomy,":[97],"which":[98],"sent":[100],"for":[101],"corneal":[102],"gram":[103],"stain,":[104],"culture":[105,129,182],"histopathology.":[107],"Topical":[108],"hourly":[109],"moxifloxacin":[110],"hydrochloride":[111],"ophthalmic":[112,119,125],"solution":[113,120],"0.5%":[114],"propamidine":[116],"isotheonate":[117],"0.1%":[118],"chlorhexidine":[122],"gluconate":[123],"0.02%":[124],"solution.":[126],"Following":[127],"pathogen,":[131],"infectious":[132],"disease":[133],"team":[134],"consulted":[136],"systemic":[139,236],"treatment":[140],"7":[142],"days":[143],"intravenous":[145],"ceftriaxone":[146],"2":[147],"grams":[148],"per":[149],"day":[150],"given.":[152],"He":[153],"had":[154],"persistent":[155],"epithelial":[156],"defect":[157],"that":[158],"resolved":[159],"after":[160],"3":[161],"weeks":[162],"from":[163],"visit":[166],"intense":[168],"regimen":[169],"ocular":[171,234],"lubrication.":[172],"Conclusion:":[173],"highlights":[177],"presentation":[180],"neisseria":[185],"meningitidis":[186,218,240],"presenting":[188,212],"ring-shaped":[191,215],"infiltrate.":[192],"Misdiagnosis":[193],"or":[194],"inappropriate":[195],"treatment,":[196],"such":[197],"as":[198,222],"use":[200],"steroids,":[202],"can":[203],"exacerbate":[204],"condition.":[206],"When":[207],"evaluating":[208],"wearers":[211],"n.":[217,239],"may":[219],"be":[220],"considered":[221],"potential":[224,233],"causative":[225],"pathogen.":[226],"However,":[227],"view":[229],"both":[231],"sequelae":[237],"infection,":[241],"it":[242],"important":[244],"to":[245],"investigate":[246],"treat":[248],"these":[249],"patients":[250],"promptly":[251],"aggressively.":[253]},"counts_by_year":[],"updated_date":"2026-10-28T10:33:24.094632","created_date":"2026-02-07T00:00:00"}