{"id":"https://openalex.org/W7127627564","doi":"https://doi.org/10.1016/j.pedhc.2025.12.021","title":"Fenofibrate vs. Omega-3 in Pediatric Hypertriglyceridemia: A Randomized Controlled Trial","display_name":"Fenofibrate vs. Omega-3 in Pediatric Hypertriglyceridemia: A Randomized Controlled Trial","publication_year":2026,"publication_date":"2026-02-04","ids":{"openalex":"https://openalex.org/W7127627564","doi":"https://doi.org/10.1016/j.pedhc.2025.12.021","pmid":"https://pubmed.ncbi.nlm.nih.gov/41636674"},"language":"en","primary_location":{"id":"doi:10.1016/j.pedhc.2025.12.021","doi":"https://doi.org/10.1016/j.pedhc.2025.12.021","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.pedhc.2025.12.021","pdf_url":null,"source":{"id":"https://openalex.org/S78878675","display_name":"Journal of Pediatric Health Care","issn_l":"0891-5245","issn":["0891-5245","1532-656X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-40","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Pediatric Health Care","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5032536152","display_name":"Setila Dalili","orcid":"https://orcid.org/0000-0001-9591-0821","observed_orcids":["https://orcid.org/0000-0001-9591-0821","https://orcid.org/0000-0003-1444-9063","https://orcid.org/0000-0002-4976-1404"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Setila Dalili","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073537736","display_name":"Shahin Koohmanaee","orcid":"https://orcid.org/0000-0001-6700-3044","observed_orcids":["https://orcid.org/0000-0001-6700-3044"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Shahin Koohmanaee","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076531959","display_name":"Afagh Hassanzadeh Rad","orcid":"https://orcid.org/0000-0001-6980-8866","observed_orcids":["https://orcid.org/0000-0001-6980-8866"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Afagh Hassanzadeh Rad","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5125016539","display_name":"Parnian Nemati","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Parnian Nemati","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059712473","display_name":"Habibeh Mashayekhi\u2010Sardoo","orcid":"https://orcid.org/0000-0002-7334-5603","observed_orcids":["https://orcid.org/0000-0002-7334-5603"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Habibeh Mashayekhi-sardoo","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-7334-5603","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5125010752","display_name":"Reza Bayat","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Reza Bayat","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5073822097","display_name":"Maryam Shahrokhi","orcid":"https://orcid.org/0000-0001-6162-750X","observed_orcids":["https://orcid.org/0000-0001-6162-750X"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Maryam Shahrokhi","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-6162-750X","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5073822097"],"corresponding_institution_ids":[],"apc_list":{"value":2930,"currency":"USD","value_usd":2930},"apc_paid":null,"fwci":5.425,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.90858014,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":92,"max":95},"biblio":{"volume":"40","issue":"5","first_page":"e207","last_page":"e214"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10394","display_name":"Lipoproteins and Cardiovascular Health","score":0.7207000255584717,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10394","display_name":"Lipoproteins and Cardiovascular Health","score":0.7207000255584717,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13430","display_name":"Lipid metabolism and disorders","score":0.2667999863624573,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10387","display_name":"Fatty Acid Research and Health","score":0.009700000286102295,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/fenofibrate","display_name":"fenofibrate","score":0.9789999723434448},{"id":"https://openalex.org/keywords/omega-3-fatty-acids","display_name":"omega-3 fatty acids","score":0.996999979019165},{"id":"https://openalex.org/keywords/triglyceride-lowering","display_name":"triglyceride lowering","score":0.9190000295639038},{"id":"https://openalex.org/keywords/ldl-cholesterol","display_name":"LDL cholesterol","score":0.9010000228881836},{"id":"https://openalex.org/keywords/total-cholesterol","display_name":"total cholesterol","score":0.8339999914169312},{"id":"https://openalex.org/keywords/hdl-cholesterol","display_name":"HDL cholesterol","score":1.0},{"id":"https://openalex.org/keywords/lipid-lowering-therapy","display_name":"lipid-lowering therapy","score":0.6880000233650208},{"id":"https://openalex.org/keywords/pediatric-drug-safety","display_name":"drug safety in children","score":0.5830000042915344}],"concepts":[{"id":"https://openalex.org/C2778110834","wikidata":"https://www.wikidata.org/wiki/Q419724","display_name":"Fenofibrate","level":2,"score":0.9075999855995178},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.890999972820282},{"id":"https://openalex.org/C168563851","wikidata":"https://www.wikidata.org/wiki/Q1436668","display_name":"Randomized controlled trial","level":2,"score":0.6340000033378601},{"id":"https://openalex.org/C535046627","wikidata":"https://www.wikidata.org/wiki/Q30612","display_name":"Clinical trial","level":2,"score":0.40869998931884766},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3463999927043915},{"id":"https://openalex.org/C2779473830","wikidata":"https://www.wikidata.org/wiki/Q1540899","display_name":"MEDLINE","level":2,"score":0.288100004196167},{"id":"https://openalex.org/C204243189","wikidata":"https://www.wikidata.org/wiki/Q1363085","display_name":"Randomization","level":3,"score":0.2451000064611435},{"id":"https://openalex.org/C202953159","wikidata":"https://www.wikidata.org/wiki/Q382695","display_name":"Intention-to-treat analysis","level":3,"score":0.22089999914169312},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.22010000050067902},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.2175000011920929}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000960","descriptor_name":"Hypolipidemic Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007492","descriptor_name":"Iran","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011345","descriptor_name":"Fenofibrate","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D014280","descriptor_name":"Triglycerides","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D015228","descriptor_name":"Hypertriglyceridemia","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D015228","descriptor_name":"Hypertriglyceridemia","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D015525","descriptor_name":"Fatty Acids, Omega-3","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.pedhc.2025.12.021","doi":"https://doi.org/10.1016/j.pedhc.2025.12.021","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.pedhc.2025.12.021","pdf_url":null,"source":{"id":"https://openalex.org/S78878675","display_name":"Journal of Pediatric Health Care","issn_l":"0891-5245","issn":["0891-5245","1532-656X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-40","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Pediatric Health Care","raw_type":"journal-article"},{"id":"pmid:41636674","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/41636674","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of pediatric health care : official publication of National Association of Pediatric Nurse Associates & Practitioners","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/randomized-controlled-trial","display_name":"Randomized Controlled Trial"},{"id":"https://openalex.org/study-designs/clinical-trial","display_name":"Clinical Trial"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320323304","display_name":"Guilan University of Medical Sciences","ror":"https://ror.org/04ptbrd12"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":30,"referenced_works":["https://openalex.org/W1982040758","https://openalex.org/W2076126598","https://openalex.org/W2103460148","https://openalex.org/W2115971212","https://openalex.org/W2116648398","https://openalex.org/W2125012558","https://openalex.org/W2150553338","https://openalex.org/W2298025084","https://openalex.org/W2753623099","https://openalex.org/W2883371150","https://openalex.org/W2953688288","https://openalex.org/W2969523838","https://openalex.org/W2980760175","https://openalex.org/W2982589837","https://openalex.org/W3034053585","https://openalex.org/W3089722040","https://openalex.org/W3116045368","https://openalex.org/W3123198570","https://openalex.org/W3136199505","https://openalex.org/W3195749557","https://openalex.org/W4210707979","https://openalex.org/W4212877560","https://openalex.org/W4213143341","https://openalex.org/W4315649291","https://openalex.org/W4319982347","https://openalex.org/W4391262070","https://openalex.org/W4394063777","https://openalex.org/W4399969291","https://openalex.org/W4400913319","https://openalex.org/W4405664227"],"related_works":["https://openalex.org/W2953688288","https://openalex.org/W3089210257","https://openalex.org/W2150553338","https://openalex.org/W2070765163","https://openalex.org/W2753623099","https://openalex.org/W2323631355","https://openalex.org/W2328574103","https://openalex.org/W1977306373","https://openalex.org/W3153852876","https://openalex.org/W7119745333"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1}],"updated_date":"2026-11-05T12:25:35.769452","created_date":"2026-02-06T00:00:00"}