{"id":"https://openalex.org/W7127601130","doi":"https://doi.org/10.51873/jhhs.v9i2.372","title":"Potensi ekstrak daun nusa indah putih (Mussaenda pubescens) sebagai agen antibakteri pada pertumbuhan Staphylococcus aureus ATCC 1055","display_name":"Potensi ekstrak daun nusa indah putih (Mussaenda pubescens) sebagai agen antibakteri pada pertumbuhan Staphylococcus aureus ATCC 1055","publication_year":2025,"publication_date":"2025-12-31","ids":{"openalex":"https://openalex.org/W7127601130","doi":"https://doi.org/10.51873/jhhs.v9i2.372"},"language":"id","primary_location":{"id":"doi:10.51873/jhhs.v9i2.372","doi":"https://doi.org/10.51873/jhhs.v9i2.372","is_oa":true,"landing_page_url":"https://doi.org/10.51873/jhhs.v9i2.372","pdf_url":"https://jhhs.stikesholistic.ac.id/index.php/jhhs/article/download/372/171","source":{"id":"https://openalex.org/S4210226250","display_name":"Journal of Holistic and Health Sciences (Jurnal Ilmu Holistik dan Kesehatan)","issn_l":"2548-9070","issn":["2548-9070","2548-9089"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4405272229","host_organization_name":"Sekolah Tinggi Ilmu Kesehatan Holistik","host_organization_lineage":["https://openalex.org/I4405272229"],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Holistic and Health Sciences (Jurnal Ilmu Holistik dan Kesehatan)","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://jhhs.stikesholistic.ac.id/index.php/jhhs/article/download/372/171","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5059857684","display_name":"Endah Kartikawati","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210121269","display_name":"Universitas Al-Ghifari","ror":"https://ror.org/02yzsqk70","country_code":"ID","type":"education","lineage":["https://openalex.org/I4210121269"]}],"countries":["ID"],"is_corresponding":false,"raw_author_name":"Endah Kartikawati","raw_affiliation_strings":["Program Studi Farmasi, Fakultas Mipa, Universitas Al Ghifari"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Program Studi Farmasi, Fakultas Mipa, Universitas Al Ghifari","institution_ids":["https://openalex.org/I4210121269"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045641871","display_name":"Taufik Septiyan Hidayat","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405272229","display_name":"Sekolah Tinggi Ilmu Kesehatan Holistik","ror":"https://ror.org/03t356073","country_code":"ID","type":"education","lineage":["https://openalex.org/I4405272229"]}],"countries":["ID"],"is_corresponding":false,"raw_author_name":"Taufik Septiyan Hidayat","raw_affiliation_strings":["Program Studi D3 Farmasi, Sekolah Tinggi Ilmu Kesehatan Holistik"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Program Studi D3 Farmasi, Sekolah Tinggi Ilmu Kesehatan Holistik","institution_ids":["https://openalex.org/I4405272229"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5125037256","display_name":"Putri Febria Imriani","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210121269","display_name":"Universitas Al-Ghifari","ror":"https://ror.org/02yzsqk70","country_code":"ID","type":"education","lineage":["https://openalex.org/I4210121269"]}],"countries":["ID"],"is_corresponding":false,"raw_author_name":"Putri Febria Imriani","raw_affiliation_strings":["Program Studi Farmasi, Fakultas Mipa, Universitas Al Ghifari"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Program Studi Farmasi, Fakultas Mipa, Universitas Al Ghifari","institution_ids":["https://openalex.org/I4210121269"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082090385","display_name":"Yunita Al Azzahra","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405276298","display_name":"Akademi Farmasi Bumi Siliwangi","ror":"https://ror.org/055d94y69","country_code":"ID","type":"education","lineage":["https://openalex.org/I4405276298"]}],"countries":["ID"],"is_corresponding":false,"raw_author_name":"Yunita Al Azzahra","raw_affiliation_strings":["Akademi Farmasi Bumi Siliwangi"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Akademi Farmasi Bumi Siliwangi","institution_ids":["https://openalex.org/I4405276298"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5045527448","display_name":"Syumillah Saepudin","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210121269","display_name":"Universitas Al-Ghifari","ror":"https://ror.org/02yzsqk70","country_code":"ID","type":"education","lineage":["https://openalex.org/I4210121269"]}],"countries":["ID"],"is_corresponding":false,"raw_author_name":"Syumillah Saepudin","raw_affiliation_strings":["Program Studi Farmasi, Fakultas Mipa, Universitas Al Ghifari"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Program Studi Farmasi, Fakultas Mipa, Universitas Al Ghifari","institution_ids":["https://openalex.org/I4210121269"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.39515071,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"9","issue":"2","first_page":"94","last_page":"104"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10225","display_name":"Essential Oils and Antimicrobial Activity","score":0.9595000147819519,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10225","display_name":"Essential Oils and Antimicrobial Activity","score":0.9595000147819519,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T14521","display_name":"Medicinal Plant Research","score":0.02979999966919422,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12181","display_name":"Agricultural and Biological Research","score":0.00139999995008111,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/mussaenda-pubescens","display_name":"Mussaenda pubescens","score":0.9789999723434448},{"id":"https://openalex.org/keywords/leaf-extract","display_name":"leaf extract","score":0.8510000109672546},{"id":"https://openalex.org/keywords/antibacterial-activity","display_name":"antibacterial activity","score":0.9950000047683716},{"id":"https://openalex.org/keywords/staphylococcus-aureus","display_name":"Staphylococcus aureus","score":0.9929999709129333},{"id":"https://openalex.org/keywords/medicinal-plants","display_name":"medicinal plants","score":0.6499999761581421},{"id":"https://openalex.org/keywords/phytochemical-screening","display_name":"phytochemical screening","score":0.921999990940094},{"id":"https://openalex.org/keywords/plant-secondary-metabolites","display_name":"plant secondary metabolites","score":0.7379999756813049},{"id":"https://openalex.org/keywords/saponins","display_name":"saponins","score":0.5950000286102295},{"id":"https://openalex.org/keywords/flavonoids","display_name":"flavonoids","score":0.871999979019165},{"id":"https://openalex.org/keywords/alkaloids","display_name":"alkaloids","score":0.847000002861023},{"id":"https://openalex.org/keywords/ethanol-maceration","display_name":"ethanol maceration","score":0.4860000014305115},{"id":"https://openalex.org/keywords/natural-antimicrobials","display_name":"natural antimicrobials","score":0.47999998927116394},{"id":"https://openalex.org/keywords/wound-infection-treatment","display_name":"wound infection treatment","score":0.4950000047683716},{"id":"https://openalex.org/keywords/crude-drug-identification","display_name":"crude drug identification","score":0.3540000021457672}],"concepts":[{"id":"https://openalex.org/C556039675","wikidata":"https://www.wikidata.org/wiki/Q771035","display_name":"Traditional medicine","level":1,"score":0.671999990940094},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.5703999996185303},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.23639999330043793},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.21819999814033508},{"id":"https://openalex.org/C31903555","wikidata":"https://www.wikidata.org/wiki/Q1637030","display_name":"Food science","level":1,"score":0.1860000044107437},{"id":"https://openalex.org/C144027150","wikidata":"https://www.wikidata.org/wiki/Q48803","display_name":"Horticulture","level":1,"score":0.16699999570846558},{"id":"https://openalex.org/C3018223157","wikidata":"https://www.wikidata.org/wiki/Q7233257","display_name":"Positive control","level":2,"score":0.15729999542236328},{"id":"https://openalex.org/C3018233652","wikidata":"https://www.wikidata.org/wiki/Q101965","display_name":"Experimental research","level":2,"score":0.15559999644756317},{"id":"https://openalex.org/C3019361144","wikidata":"https://www.wikidata.org/wiki/Q367359","display_name":"Negative control","level":2,"score":0.14419999718666077},{"id":"https://openalex.org/C2779489039","wikidata":"https://www.wikidata.org/wiki/Q188121","display_name":"Staphylococcus aureus","level":3,"score":0.13539999723434448}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.51873/jhhs.v9i2.372","doi":"https://doi.org/10.51873/jhhs.v9i2.372","is_oa":true,"landing_page_url":"https://doi.org/10.51873/jhhs.v9i2.372","pdf_url":"https://jhhs.stikesholistic.ac.id/index.php/jhhs/article/download/372/171","source":{"id":"https://openalex.org/S4210226250","display_name":"Journal of Holistic and Health Sciences (Jurnal Ilmu Holistik dan Kesehatan)","issn_l":"2548-9070","issn":["2548-9070","2548-9089"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4405272229","host_organization_name":"Sekolah Tinggi Ilmu Kesehatan Holistik","host_organization_lineage":["https://openalex.org/I4405272229"],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Holistic and Health Sciences (Jurnal Ilmu Holistik dan Kesehatan)","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.51873/jhhs.v9i2.372","doi":"https://doi.org/10.51873/jhhs.v9i2.372","is_oa":true,"landing_page_url":"https://doi.org/10.51873/jhhs.v9i2.372","pdf_url":"https://jhhs.stikesholistic.ac.id/index.php/jhhs/article/download/372/171","source":{"id":"https://openalex.org/S4210226250","display_name":"Journal of Holistic and Health Sciences (Jurnal Ilmu Holistik dan Kesehatan)","issn_l":"2548-9070","issn":["2548-9070","2548-9089"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4405272229","host_organization_name":"Sekolah Tinggi Ilmu Kesehatan Holistik","host_organization_lineage":["https://openalex.org/I4405272229"],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Holistic and Health Sciences (Jurnal Ilmu Holistik dan Kesehatan)","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.428600013256073,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7127601130.pdf","grobid_xml":"https://content.openalex.org/works/W7127601130.grobid-xml"},"referenced_works_count":3,"referenced_works":["https://openalex.org/W4393308912","https://openalex.org/W4393318040","https://openalex.org/W4405983313"],"related_works":["https://openalex.org/W4386894192","https://openalex.org/W3118348166","https://openalex.org/W4385613844","https://openalex.org/W7034511188","https://openalex.org/W7020046144","https://openalex.org/W2996028041","https://openalex.org/W4393018781","https://openalex.org/W2983070026","https://openalex.org/W1498015570","https://openalex.org/W3005906789"],"abstract_inverted_index":{"Latar":[0],"Belakang:":[1],"Masyarakat":[2],"Indonesia":[3],"telah":[4],"lama":[5],"memanfaatkan":[6],"tanaman":[7,26],"obat":[8],"sebagai":[9,47,111],"alternatif":[10],"pengobatan":[11],"alami,":[12],"termasuk":[13],"daun":[14,64,133,183,199],"Mussaenda":[15],"pubescens":[16],"(Nusa":[17],"Indah":[18,66,135,185],"Putih)":[19],"yang":[20,43,78,167],"memiliki":[21,28],"senyawa":[22,125,189],"bioaktif.":[23],"Metabolit":[24],"sekunder":[25],"ini":[27,56],"khasiat":[29],"dalam":[30],"mengatasi":[31],"penyakit":[32,34],"-":[33],"infeksi,":[35],"salah":[36],"satunya":[37],"disebabkan":[38],"oleh":[39,172],"Staphylococcus":[40,140,210],"aureus,":[41],"bakteri":[42,70],"secara":[44],"alami":[45],"ditemukan":[46],"flora":[48],"normal":[49],"namun":[50],"juga":[51],"patogen":[52],"oportunistik.":[53],"Tujuan:":[54],"Penelitian":[55],"dilakukan":[57],"untuk":[58],"mengidentifikasi":[59],"kemampuan":[60,207],"antibakteri":[61,205],"dari":[62],"ekstrak":[63,100,182,198],"Nusa":[65,134,184],"Putih":[67,136,186],"pada":[68,107,145,174],"pertumbuhan":[69,139,209],"S.":[71],"aureus.":[72,211],"Metode:":[73],"Metode":[74],"penelitiannya":[75],"adalah":[76],"eksperimental":[77],"kegiatannya":[79],"meliputi":[80],"determinasi,":[81],"membuat":[82],"simplisia,":[83],"menetapkan":[84],"kadar":[85],"air":[86],"dan":[87,104,114,130,160],"susut":[88],"pengeringan,":[89],"ekstraksi":[90],"dengan":[91,109,142,206],"maserasi":[92],"etanol":[93],"70%,":[94],"serta":[95,194],"skrining":[96,121],"fitokimia.":[97],"Berbagai":[98],"konsentrasi":[99,146,157],"(50%,":[101],"25%,":[102,158],"12,5%,":[103,159],"6,25%)":[105],"diteteskan":[106],"cakram,":[108],"kloramfenikol":[110],"kontrol":[112,117],"positif":[113],"DMSO":[115],"5%":[116],"negatif.":[118],"Hasil:":[119],"Hasil":[120],"fitokimia":[122],"teridentifikasi":[123,187],"adanya":[124,188],"saponin,":[126,193],"alkaloid,":[127,190],"tanin,":[128,192],"flavonoid,":[129,191],"terpenoid/steroid.":[131],"Ekstrak":[132],"mampu":[137],"menghambat":[138,208],"aureus":[141],"kategori":[143],"sedang":[144],"50%":[147],"(zona":[148],"hambat":[149],"5,8":[150],"mm":[151],"setelah":[152,170],"dikurangi":[153],"disc":[154],"kosong),":[155],"sedangkan":[156],"6,25%":[161],"menghasilkan":[162],"hambatan":[163],"lemah.":[164],"Diperoleh":[165],"perbedaan":[166],"signifikan":[168],"(p<0,05)":[169],"dianalisis":[171],"ANOVA":[173],"tiap":[175],"kelompok":[176],"perlakuan.":[177],"Simpulan:":[178],"Berdasarkan":[179],"hasil":[180],"penelitian,":[181],"steroid/terpenoid.":[195],"Selain":[196],"itu,":[197],"nusa":[200],"indah":[201],"putih":[202],"menunjukkan":[203],"aktivitas":[204]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2026-02-06T00:00:00"}