{"id":"https://openalex.org/W7127419485","doi":"https://doi.org/10.1016/j.jtct.2025.12.362","title":"Impact of HLA Alloimmunization on Availability of HLA Matched and Mismatched Unrelated Allogeneic Hematopoietic Cell Donors for Transplantation Disproportionately Impacts Female Patients","display_name":"Impact of HLA Alloimmunization on Availability of HLA Matched and Mismatched Unrelated Allogeneic Hematopoietic Cell Donors for Transplantation Disproportionately Impacts Female Patients","publication_year":2026,"publication_date":"2026-02-01","ids":{"openalex":"https://openalex.org/W7127419485","doi":"https://doi.org/10.1016/j.jtct.2025.12.362"},"language":"en","primary_location":{"id":"doi:10.1016/j.jtct.2025.12.362","doi":"https://doi.org/10.1016/j.jtct.2025.12.362","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.jtct.2025.12.362","pdf_url":null,"source":{"id":"https://openalex.org/S59987174","display_name":"Transplantation and Cellular Therapy","issn_l":"1083-8791","issn":["1083-8791","1523-6536","2666-6367"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","poland-20","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Transplantation and Cellular Therapy","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5064076262","display_name":"Brian C. Shaffer","orcid":"https://orcid.org/0000-0003-3433-9179","observed_orcids":["https://orcid.org/0000-0003-3433-9179"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]},{"id":"https://openalex.org/I4387153466","display_name":"Weill Cornell Medicine","ror":"https://ror.org/02r109517","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295","https://openalex.org/I4387153466"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Brian C. Shaffer","raw_affiliation_strings":["Adult BMT Service, Memorial Sloan Kettering Cancer Center, New York, NY","Department of Medicine, Weill Cornell Medical College, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Adult BMT Service, Memorial Sloan Kettering Cancer Center, New York, NY","institution_ids":["https://openalex.org/I1334819555"]},{"raw_affiliation_string":"Department of Medicine, Weill Cornell Medical College, New York, NY","institution_ids":["https://openalex.org/I4387153466"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075049896","display_name":"Amanda G. Blouin","orcid":"https://orcid.org/0000-0003-2238-4837","observed_orcids":["https://orcid.org/0000-0003-2238-4837"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Amanda G Blouin","raw_affiliation_strings":["Adult BMT Service, Memorial Sloan Kettering Cancer Center, New York, NY","Department of Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Adult BMT Service, Memorial Sloan Kettering Cancer Center, New York, NY","institution_ids":["https://openalex.org/I1334819555"]},{"raw_affiliation_string":"Department of Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006014600","display_name":"Candice Rapoport","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Candice Rapoport","raw_affiliation_strings":["Adult BMT Service, Memorial Sloan Kettering Cancer Center, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Adult BMT Service, Memorial Sloan Kettering Cancer Center, New York, NY","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035410009","display_name":"Deborah S. Wells","orcid":"https://orcid.org/0000-0002-9404-1705","observed_orcids":["https://orcid.org/0000-0002-9404-1705"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Deborah S. Wells","raw_affiliation_strings":["Adult BMT Service, Memorial Sloan Kettering Cancer Center, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Adult BMT Service, Memorial Sloan Kettering Cancer Center, New York, NY","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011056604","display_name":"Stephanie Chinapen","orcid":"https://orcid.org/0000-0001-6308-9346","observed_orcids":["https://orcid.org/0000-0001-6308-9346"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ms. Stephanie Chinapen","raw_affiliation_strings":["Adult BMT Service, Memorial Sloan Kettering Cancer Center, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Adult BMT Service, Memorial Sloan Kettering Cancer Center, New York, NY","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082333371","display_name":"Miguel\u2010Angel Perales","orcid":"https://orcid.org/0000-0002-5910-4571","observed_orcids":["https://orcid.org/0000-0002-5910-4571"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]},{"id":"https://openalex.org/I4387153466","display_name":"Weill Cornell Medicine","ror":"https://ror.org/02r109517","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295","https://openalex.org/I4387153466"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Miguel-Angel Perales","raw_affiliation_strings":["Adult BMT Service, Memorial Sloan Kettering Cancer Center, New York, NY","Department of Medicine, Weill Cornell Medical College, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Adult BMT Service, Memorial Sloan Kettering Cancer Center, New York, NY","institution_ids":["https://openalex.org/I1334819555"]},{"raw_affiliation_string":"Department of Medicine, Weill Cornell Medical College, New York, NY","institution_ids":["https://openalex.org/I4387153466"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007847102","display_name":"Steven Michael Devine","orcid":"https://orcid.org/0000-0001-7731-759X","observed_orcids":["https://orcid.org/0000-0001-7731-759X"]},"institutions":[{"id":"https://openalex.org/I1318116459","display_name":"National Marrow Donor Program","ror":"https://ror.org/016cke005","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I1318116459"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Steven M Devine","raw_affiliation_strings":["CIBMTR\u00ae (Center for International Blood and Marrow Transplant Research), NMDP, Minneapolis, MN"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CIBMTR\u00ae (Center for International Blood and Marrow Transplant Research), NMDP, Minneapolis, MN","institution_ids":["https://openalex.org/I1318116459"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085657767","display_name":"Jeffery James Auletta","orcid":"https://orcid.org/0000-0002-1515-2141","observed_orcids":["https://orcid.org/0000-0002-1515-2141"]},"institutions":[{"id":"https://openalex.org/I1318116459","display_name":"National Marrow Donor Program","ror":"https://ror.org/016cke005","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I1318116459"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Dr. Jeffery J. Auletta","raw_affiliation_strings":["CIBMTR\u00ae (Center for International Blood and Marrow Transplant Research), NMDP, Minneapolis, MN"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CIBMTR\u00ae (Center for International Blood and Marrow Transplant Research), NMDP, Minneapolis, MN","institution_ids":["https://openalex.org/I1318116459"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052844124","display_name":"Heather Emily Stefanski","orcid":"https://orcid.org/0000-0001-7527-9315","observed_orcids":["https://orcid.org/0000-0001-7527-9315","https://orcid.org/0009-0000-0554-3213"]},"institutions":[{"id":"https://openalex.org/I1318116459","display_name":"National Marrow Donor Program","ror":"https://ror.org/016cke005","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I1318116459"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Dr. Heather E. Stefanski","raw_affiliation_strings":["CIBMTR\u00ae (Center for International Blood and Marrow Transplant Research), NMDP, Minneapolis, MN"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CIBMTR\u00ae (Center for International Blood and Marrow Transplant Research), NMDP, Minneapolis, MN","institution_ids":["https://openalex.org/I1318116459"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064818358","display_name":"Stephen R. Spellman","orcid":"https://orcid.org/0000-0002-7271-8252","observed_orcids":["https://orcid.org/0000-0002-7271-8252"]},"institutions":[{"id":"https://openalex.org/I1318116459","display_name":"National Marrow Donor Program","ror":"https://ror.org/016cke005","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I1318116459"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Stephen R. Spellman","raw_affiliation_strings":["CIBMTR\u00ae (Center for International Blood and Marrow Transplant Research), NMDP, Minneapolis, MN"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CIBMTR\u00ae (Center for International Blood and Marrow Transplant Research), NMDP, Minneapolis, MN","institution_ids":["https://openalex.org/I1318116459"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5036285459","display_name":"Martin J. Maiers","orcid":"https://orcid.org/0000-0002-0198-2064","observed_orcids":["https://orcid.org/0000-0002-0198-2064"]},"institutions":[{"id":"https://openalex.org/I1318116459","display_name":"National Marrow Donor Program","ror":"https://ror.org/016cke005","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I1318116459"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Martin Maiers","raw_affiliation_strings":["CIBMTR\u00ae (Center for International Blood and Marrow Transplant Research), NMDP, Minneapolis, MN"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CIBMTR\u00ae (Center for International Blood and Marrow Transplant Research), NMDP, Minneapolis, MN","institution_ids":["https://openalex.org/I1318116459"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5064076262"],"corresponding_institution_ids":["https://openalex.org/I1334819555","https://openalex.org/I4387153466"],"apc_list":{"value":3650,"currency":"USD","value_usd":3650},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.07108129,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"32","issue":"2","first_page":"S254","last_page":"S255"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10345","display_name":"Hematopoietic Stem Cell Transplantation","score":0.9937000274658203,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10345","display_name":"Hematopoietic Stem Cell Transplantation","score":0.9937000274658203,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10373","display_name":"Renal Transplantation Outcomes and Treatments","score":0.0027000000700354576,"subfield":{"id":"https://openalex.org/subfields/2747","display_name":"Transplantation"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11660","display_name":"Blood groups and transfusion","score":0.0010999999940395355,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hla-alloimmunization","display_name":"HLA sensitization","score":0.9990000128746033},{"id":"https://openalex.org/keywords/anti-hla-antibodies","display_name":"HLA antibodies","score":0.9570000171661377},{"id":"https://openalex.org/keywords/donor-specific-antibodies","display_name":"donor-specific antibodies","score":0.5730000138282776},{"id":"https://openalex.org/keywords/hematopoietic-stem-cell-transplantation","display_name":"hematopoietic stem cell transplantation","score":0.8420000076293945},{"id":"https://openalex.org/keywords/sex-differences","display_name":"sex differences","score":0.47699999809265137},{"id":"https://openalex.org/keywords/female-patients","display_name":"female patients","score":0.6159999966621399},{"id":"https://openalex.org/keywords/hla-matching","display_name":"HLA matching","score":0.4429999887943268},{"id":"https://openalex.org/keywords/hla-mismatch","display_name":"HLA mismatch","score":0.38100001215934753},{"id":"https://openalex.org/keywords/mean-fluorescence-intensity","display_name":"mean fluorescence intensity","score":0.5239999890327454},{"id":"https://openalex.org/keywords/immunodepletion","display_name":"immunodepletion","score":0.5130000114440918},{"id":"https://openalex.org/keywords/allogeneic-hematopoietic-stem-cell-transplantation","display_name":"allogeneic hematopoietic stem cell transplantation","score":0.6970000267028809},{"id":"https://openalex.org/keywords/racial-and-ethnic-disparities","display_name":"racial and ethnic disparities","score":0.39500001072883606}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8066999912261963},{"id":"https://openalex.org/C188280979","wikidata":"https://www.wikidata.org/wiki/Q911125","display_name":"Human leukocyte antigen","level":3,"score":0.7243000268936157},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.5756000280380249},{"id":"https://openalex.org/C2777408962","wikidata":"https://www.wikidata.org/wiki/Q1128050","display_name":"Hematopoietic stem cell transplantation","level":3,"score":0.5501999855041504},{"id":"https://openalex.org/C72563966","wikidata":"https://www.wikidata.org/wiki/Q1303415","display_name":"Cohort","level":2,"score":0.5426999926567078},{"id":"https://openalex.org/C2911091166","wikidata":"https://www.wikidata.org/wiki/Q106419912","display_name":"Transplantation","level":2,"score":0.5421000123023987},{"id":"https://openalex.org/C2993713153","wikidata":"https://www.wikidata.org/wiki/Q211709","display_name":"Hematopoietic cell","level":4,"score":0.522599995136261},{"id":"https://openalex.org/C31467283","wikidata":"https://www.wikidata.org/wiki/Q912147","display_name":"Genotyping","level":4,"score":0.4749999940395355},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.41280001401901245},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.41040000319480896},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.40799999237060547},{"id":"https://openalex.org/C147483822","wikidata":"https://www.wikidata.org/wiki/Q103537","display_name":"Antigen","level":2,"score":0.40560001134872437},{"id":"https://openalex.org/C2909478873","wikidata":"https://www.wikidata.org/wiki/Q3991680","display_name":"Histocompatibility Testing","level":4,"score":0.40310001373291016},{"id":"https://openalex.org/C2781197716","wikidata":"https://www.wikidata.org/wiki/Q864574","display_name":"Biomarker","level":2,"score":0.3889000117778778},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.3208000063896179},{"id":"https://openalex.org/C201903717","wikidata":"https://www.wikidata.org/wiki/Q1778788","display_name":"Cohort study","level":2,"score":0.30390000343322754},{"id":"https://openalex.org/C10515644","wikidata":"https://www.wikidata.org/wiki/Q543310","display_name":"Survival analysis","level":2,"score":0.29820001125335693},{"id":"https://openalex.org/C188816634","wikidata":"https://www.wikidata.org/wiki/Q2113324","display_name":"Prospective cohort study","level":2,"score":0.2734000086784363},{"id":"https://openalex.org/C2779972918","wikidata":"https://www.wikidata.org/wiki/Q1194520","display_name":"Graft-versus-host disease","level":3,"score":0.2721000015735626},{"id":"https://openalex.org/C202965653","wikidata":"https://www.wikidata.org/wiki/Q2664028","display_name":"Histocompatibility","level":4,"score":0.267300009727478}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/j.jtct.2025.12.362","doi":"https://doi.org/10.1016/j.jtct.2025.12.362","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.jtct.2025.12.362","pdf_url":null,"source":{"id":"https://openalex.org/S59987174","display_name":"Transplantation and Cellular Therapy","issn_l":"1083-8791","issn":["1083-8791","1523-6536","2666-6367"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","poland-20","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Transplantation and Cellular Therapy","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4417015806","https://openalex.org/W4385814261","https://openalex.org/W2612641454","https://openalex.org/W2913610446","https://openalex.org/W2555326026","https://openalex.org/W2981305306","https://openalex.org/W4392767129","https://openalex.org/W2086705945","https://openalex.org/W2068955071","https://openalex.org/W3087284399"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-12T09:40:04.860316","created_date":"2026-02-04T00:00:00"}
