{"id":"https://openalex.org/W7127067352","doi":"https://doi.org/10.1016/j.foodres.2026.118558","title":"Hepatoprotective potential of anthocyanins from purple highland barley bran against non-alcoholic fatty liver disease through gut-liver axis","display_name":"Hepatoprotective potential of anthocyanins from purple highland barley bran against non-alcoholic fatty liver disease through gut-liver axis","publication_year":2026,"publication_date":"2026-02-03","ids":{"openalex":"https://openalex.org/W7127067352","doi":"https://doi.org/10.1016/j.foodres.2026.118558","pmid":"https://pubmed.ncbi.nlm.nih.gov/41794448"},"language":"en","primary_location":{"id":"doi:10.1016/j.foodres.2026.118558","doi":"https://doi.org/10.1016/j.foodres.2026.118558","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.foodres.2026.118558","pdf_url":null,"source":{"id":"https://openalex.org/S38919146","display_name":"Food Research International","issn_l":"0963-9969","issn":["0963-9969","1873-7145"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-2","ki-jl-1","medline","norway-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Food Research International","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5018261592","display_name":"Yongzhu Zhang","orcid":"https://orcid.org/0000-0001-5379-5239","observed_orcids":["https://orcid.org/0000-0001-5379-5239"]},"institutions":[{"id":"https://openalex.org/I1284762954","display_name":"Zhejiang A & F University","ror":"https://ror.org/02vj4rn06","country_code":"CN","type":"education","lineage":["https://openalex.org/I1284762954"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Yongzhu Zhang","raw_affiliation_strings":["National Key Laboratory for Development and Utilization of Forest Food Resources, College of Food and Health, Zhejiang A&F University, Hangzhou 311300, China. Electronic address: zhangyz@zafu.edu.cn"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Key Laboratory for Development and Utilization of Forest Food Resources, College of Food and Health, Zhejiang A&F University, Hangzhou 311300, China. Electronic address: zhangyz@zafu.edu.cn","institution_ids":["https://openalex.org/I1284762954"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5124853779","display_name":"Yixue Zhou","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1284762954","display_name":"Zhejiang A & F University","ror":"https://ror.org/02vj4rn06","country_code":"CN","type":"education","lineage":["https://openalex.org/I1284762954"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yixue Zhou","raw_affiliation_strings":["National Key Laboratory for Development and Utilization of Forest Food Resources, College of Food and Health, Zhejiang A&F University, Hangzhou 311300, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Key Laboratory for Development and Utilization of Forest Food Resources, College of Food and Health, Zhejiang A&F University, Hangzhou 311300, China","institution_ids":["https://openalex.org/I1284762954"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111187250","display_name":"Guanyu Fang","orcid":"https://orcid.org/0000-0002-8822-2059","observed_orcids":["https://orcid.org/0000-0002-8822-2059"]},"institutions":[{"id":"https://openalex.org/I1284762954","display_name":"Zhejiang A & F University","ror":"https://ror.org/02vj4rn06","country_code":"CN","type":"education","lineage":["https://openalex.org/I1284762954"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Guanyu Fang","raw_affiliation_strings":["National Key Laboratory for Development and Utilization of Forest Food Resources, College of Food and Health, Zhejiang A&F University, Hangzhou 311300, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Key Laboratory for Development and Utilization of Forest Food Resources, College of Food and Health, Zhejiang A&F University, Hangzhou 311300, China","institution_ids":["https://openalex.org/I1284762954"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087154310","display_name":"Fidelis Azi","orcid":"https://orcid.org/0000-0001-8986-5630","observed_orcids":["https://orcid.org/0000-0001-8986-5630"]},"institutions":[{"id":"https://openalex.org/I4210138813","display_name":"Guangdong Technion-Israel Institute of Technology","ror":"https://ror.org/04rctme81","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210138813"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Fidelis Azi","raw_affiliation_strings":["Chemical Engineering Laboratory, Synthetic Biology and Intelligent Control Unit, Guangdong Technion Isreal Institute of Technology, Shantou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Chemical Engineering Laboratory, Synthetic Biology and Intelligent Control Unit, Guangdong Technion Isreal Institute of Technology, Shantou, China","institution_ids":["https://openalex.org/I4210138813"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5124819239","display_name":"Zhenduo Gao","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1284762954","display_name":"Zhejiang A & F University","ror":"https://ror.org/02vj4rn06","country_code":"CN","type":"education","lineage":["https://openalex.org/I1284762954"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhenduo Gao","raw_affiliation_strings":["National Key Laboratory for Development and Utilization of Forest Food Resources, College of Food and Health, Zhejiang A&F University, Hangzhou 311300, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Key Laboratory for Development and Utilization of Forest Food Resources, College of Food and Health, Zhejiang A&F University, Hangzhou 311300, China","institution_ids":["https://openalex.org/I1284762954"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102746353","display_name":"Fenghua Wu","orcid":"https://orcid.org/0000-0002-4765-1973","observed_orcids":["https://orcid.org/0000-0002-4765-1973","https://orcid.org/0009-0004-2941-2532"]},"institutions":[{"id":"https://openalex.org/I1284762954","display_name":"Zhejiang A & F University","ror":"https://ror.org/02vj4rn06","country_code":"CN","type":"education","lineage":["https://openalex.org/I1284762954"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Fenghua Wu","raw_affiliation_strings":["National Key Laboratory for Development and Utilization of Forest Food Resources, College of Food and Health, Zhejiang A&F University, Hangzhou 311300, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Key Laboratory for Development and Utilization of Forest Food Resources, College of Food and Health, Zhejiang A&F University, Hangzhou 311300, China","institution_ids":["https://openalex.org/I1284762954"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087761962","display_name":"Linshu Jiao","orcid":"https://orcid.org/0000-0002-6101-9624","observed_orcids":["https://orcid.org/0000-0002-6101-9624"]},"institutions":[{"id":"https://openalex.org/I4210087107","display_name":"Jiangsu Academy of Agricultural Sciences","ror":"https://ror.org/001f9e125","country_code":"CN","type":"government","lineage":["https://openalex.org/I4210087107"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Linshu Jiao","raw_affiliation_strings":["Institute of Food Safety and Nutrition, Key Lab of Food Quality and Safety of Jiangsu Province-state Key Laboratory Breeding Base, Jiangsu Academy of Agricultural Sciences, Nanjing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Food Safety and Nutrition, Key Lab of Food Quality and Safety of Jiangsu Province-state Key Laboratory Breeding Base, Jiangsu Academy of Agricultural Sciences, Nanjing, China","institution_ids":["https://openalex.org/I4210087107"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5124801872","display_name":"Ran Wang","orcid":"https://orcid.org/0000-0001-7237-6937","observed_orcids":["https://orcid.org/0000-0001-7237-6937"]},"institutions":[{"id":"https://openalex.org/I4210087107","display_name":"Jiangsu Academy of Agricultural Sciences","ror":"https://ror.org/001f9e125","country_code":"CN","type":"government","lineage":["https://openalex.org/I4210087107"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ran Wang","raw_affiliation_strings":["Institute of Food Safety and Nutrition, Key Lab of Food Quality and Safety of Jiangsu Province-state Key Laboratory Breeding Base, Jiangsu Academy of Agricultural Sciences, Nanjing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Food Safety and Nutrition, Key Lab of Food Quality and Safety of Jiangsu Province-state Key Laboratory Breeding Base, Jiangsu Academy of Agricultural Sciences, Nanjing, China","institution_ids":["https://openalex.org/I4210087107"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5114083068","display_name":"Baiyi Lu","orcid":"https://orcid.org/0000-0002-7573-0679","observed_orcids":["https://orcid.org/0000-0002-7573-0679"]},"institutions":[{"id":"https://openalex.org/I4210151987","display_name":"Ministry of Agriculture and Rural Affairs","ror":"https://ror.org/05ckt8b96","country_code":"CN","type":"government","lineage":["https://openalex.org/I4210127390","https://openalex.org/I4210151987"]},{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Baiyi Lu","raw_affiliation_strings":["College of Biosystems Engineering and Food Science, Key Laboratory for Quality Evaluation and Health Benefit of Agro-Products of Ministry of Agriculture and Rural Affairs, Key Laboratory for Quality and Safety Risk Assessment of Agro-Products Storage and Preservation of Ministry of Agriculture and Rural Affairs, Zhejiang University, Hangzhou, China. Electronic address: bylu@zju.edu.cn"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Biosystems Engineering and Food Science, Key Laboratory for Quality Evaluation and Health Benefit of Agro-Products of Ministry of Agriculture and Rural Affairs, Key Laboratory for Quality and Safety Risk Assessment of Agro-Products Storage and Preservation of Ministry of Agriculture and Rural Affairs, Zhejiang University, Hangzhou, China. Electronic address: bylu@zju.edu.cn","institution_ids":["https://openalex.org/I4210151987","https://openalex.org/I76130692"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5101429043","display_name":"Xingquan Liu","orcid":"https://orcid.org/0000-0001-5578-9182","observed_orcids":["https://orcid.org/0000-0001-5578-9182"]},"institutions":[{"id":"https://openalex.org/I1284762954","display_name":"Zhejiang A & F University","ror":"https://ror.org/02vj4rn06","country_code":"CN","type":"education","lineage":["https://openalex.org/I1284762954"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Xingquan Liu","raw_affiliation_strings":["National Key Laboratory for Development and Utilization of Forest Food Resources, College of Food and Health, Zhejiang A&F University, Hangzhou 311300, China. Electronic address: liuxq@zafu.edu.cn"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Key Laboratory for Development and Utilization of Forest Food Resources, College of Food and Health, Zhejiang A&F University, Hangzhou 311300, China. Electronic address: liuxq@zafu.edu.cn","institution_ids":["https://openalex.org/I1284762954"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5018261592","https://openalex.org/A5101429043","https://openalex.org/A5114083068"],"corresponding_institution_ids":["https://openalex.org/I1284762954","https://openalex.org/I4210151987","https://openalex.org/I76130692"],"apc_list":{"value":4320,"currency":"USD","value_usd":4320},"apc_paid":null,"fwci":13.4142,"has_fulltext":false,"cited_by_count":3,"citation_normalized_percentile":{"value":0.98367305,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":97,"max":98},"biblio":{"volume":"230","issue":null,"first_page":"118558","last_page":"118558"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10351","display_name":"Liver Disease Diagnosis and Treatment","score":0.6445000171661377,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10351","display_name":"Liver Disease Diagnosis and Treatment","score":0.6445000171661377,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10035","display_name":"Phytochemicals and Antioxidant Activities","score":0.17090000212192535,"subfield":{"id":"https://openalex.org/subfields/2704","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11140","display_name":"Natural Antidiabetic Agents Studies","score":0.032499998807907104,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/anthocyanins","display_name":"anthocyanins","score":0.9380000233650208},{"id":"https://openalex.org/keywords/non-alcoholic-fatty-liver-disease","display_name":"non-alcoholic fatty liver disease","score":0.9959999918937683},{"id":"https://openalex.org/keywords/hepatoprotective-effect","display_name":"hepatoprotection","score":0.8930000066757202},{"id":"https://openalex.org/keywords/gut-liver-axis","display_name":"gut-liver axis","score":1.0},{"id":"https://openalex.org/keywords/nrf2-signaling-pathway","display_name":"Nrf2 signaling","score":0.777999997138977},{"id":"https://openalex.org/keywords/p38-mapk","display_name":"p38 MAPK","score":0.9369999766349792},{"id":"https://openalex.org/keywords/oxidative-stress","display_name":"oxidative stress","score":0.8830000162124634},{"id":"https://openalex.org/keywords/intestinal-barrier-function","display_name":"intestinal barrier function","score":0.8489999771118164},{"id":"https://openalex.org/keywords/gut-dysbiosis","display_name":"gut dysbiosis","score":0.8920000195503235},{"id":"https://openalex.org/keywords/high-fat-diet","display_name":"high-fat diet","score":0.7149999737739563},{"id":"https://openalex.org/keywords/pancreatic-lipase-inhibition","display_name":"pancreatic lipase inhibition","score":0.7540000081062317},{"id":"https://openalex.org/keywords/resistant-starch","display_name":"resistant starch","score":0.9309999942779541},{"id":"https://openalex.org/keywords/flavonoid-biosynthesis","display_name":"flavonoid biosynthesis","score":0.6940000057220459},{"id":"https://openalex.org/keywords/colonic-metabolites","display_name":"colonic metabolites","score":0.5649999976158142},{"id":"https://openalex.org/keywords/dietary-polyphenols","display_name":"dietary polyphenols","score":0.628000020980835}],"concepts":[{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5982000231742859},{"id":"https://openalex.org/C2778772119","wikidata":"https://www.wikidata.org/wiki/Q6058862","display_name":"Fatty liver","level":3,"score":0.5163999795913696},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.4876999855041504},{"id":"https://openalex.org/C2776873940","wikidata":"https://www.wikidata.org/wiki/Q188672","display_name":"Bran","level":3,"score":0.461899995803833},{"id":"https://openalex.org/C2776633847","wikidata":"https://www.wikidata.org/wiki/Q574416","display_name":"Resistant starch","level":3,"score":0.4593999981880188},{"id":"https://openalex.org/C2781403372","wikidata":"https://www.wikidata.org/wiki/Q207688","display_name":"Oleic acid","level":2,"score":0.42179998755455017},{"id":"https://openalex.org/C543025807","wikidata":"https://www.wikidata.org/wiki/Q61476","display_name":"Fatty acid","level":2,"score":0.41290000081062317},{"id":"https://openalex.org/C31903555","wikidata":"https://www.wikidata.org/wiki/Q1637030","display_name":"Food science","level":1,"score":0.412200003862381},{"id":"https://openalex.org/C2778913445","wikidata":"https://www.wikidata.org/wiki/Q186319","display_name":"Triglyceride","level":3,"score":0.3880000114440918},{"id":"https://openalex.org/C529335014","wikidata":"https://www.wikidata.org/wiki/Q41534","display_name":"Starch","level":2,"score":0.3644999861717224},{"id":"https://openalex.org/C2778163477","wikidata":"https://www.wikidata.org/wiki/Q43656","display_name":"Cholesterol","level":2,"score":0.36160001158714294},{"id":"https://openalex.org/C200514077","wikidata":"https://www.wikidata.org/wiki/Q407758","display_name":"Glyceride","level":3,"score":0.32760000228881836},{"id":"https://openalex.org/C2777312293","wikidata":"https://www.wikidata.org/wiki/Q3649349","display_name":"Mucus","level":2,"score":0.3222000002861023},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.3172999918460846},{"id":"https://openalex.org/C2776415932","wikidata":"https://www.wikidata.org/wiki/Q48743","display_name":"Western blot","level":3,"score":0.31520000100135803},{"id":"https://openalex.org/C2778573061","wikidata":"https://www.wikidata.org/wiki/Q1139400","display_name":"Exudate","level":2,"score":0.3028999865055084},{"id":"https://openalex.org/C2775941134","wikidata":"https://www.wikidata.org/wiki/Q813622","display_name":"Goblet cell","level":3,"score":0.30169999599456787},{"id":"https://openalex.org/C553450214","wikidata":"https://www.wikidata.org/wiki/Q851162","display_name":"Biosynthesis","level":3,"score":0.29499998688697815},{"id":"https://openalex.org/C2779054382","wikidata":"https://www.wikidata.org/wiki/Q72185287","display_name":"Flavonoid","level":3,"score":0.28949999809265137},{"id":"https://openalex.org/C2776151105","wikidata":"https://www.wikidata.org/wiki/Q898814","display_name":"Oxidative stress","level":2,"score":0.28700000047683716},{"id":"https://openalex.org/C2776714187","wikidata":"https://www.wikidata.org/wiki/Q212410","display_name":"Protease","level":3,"score":0.2822999954223633},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.26829999685287476},{"id":"https://openalex.org/C2777075537","wikidata":"https://www.wikidata.org/wiki/Q929737","display_name":"Liver disease","level":2,"score":0.26809999346733093},{"id":"https://openalex.org/C2776229602","wikidata":"https://www.wikidata.org/wiki/Q2698455","display_name":"Short-chain fatty acid","level":4,"score":0.2676999866962433},{"id":"https://openalex.org/C51551487","wikidata":"https://www.wikidata.org/wiki/Q2043632","display_name":"p38 mitogen-activated protein kinases","level":4,"score":0.25999999046325684}],"mesh":[{"descriptor_ui":"D000069196","descriptor_name":"Gastrointestinal Microbiome","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D000069196","descriptor_name":"Gastrointestinal Microbiome","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000872","descriptor_name":"Anthocyanins","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D000872","descriptor_name":"Anthocyanins","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D000872","descriptor_name":"Anthocyanins","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D000872","descriptor_name":"Anthocyanins","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D001467","descriptor_name":"Hordeum","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D001467","descriptor_name":"Hordeum","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D001467","descriptor_name":"Hordeum","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D001467","descriptor_name":"Hordeum","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D004195","descriptor_name":"Disease Models, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004195","descriptor_name":"Disease Models, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004195","descriptor_name":"Disease Models, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004195","descriptor_name":"Disease Models, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008099","descriptor_name":"Liver","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D008099","descriptor_name":"Liver","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D008099","descriptor_name":"Liver","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D008099","descriptor_name":"Liver","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D008099","descriptor_name":"Liver","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D008099","descriptor_name":"Liver","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D008099","descriptor_name":"Liver","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D008099","descriptor_name":"Liver","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008810","descriptor_name":"Mice, Inbred C57BL","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008810","descriptor_name":"Mice, Inbred C57BL","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008810","descriptor_name":"Mice, Inbred C57BL","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008810","descriptor_name":"Mice, Inbred C57BL","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010936","descriptor_name":"Plant Extracts","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D010936","descriptor_name":"Plant Extracts","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D010936","descriptor_name":"Plant Extracts","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D010936","descriptor_name":"Plant Extracts","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D018384","descriptor_name":"Oxidative Stress","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D018384","descriptor_name":"Oxidative Stress","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D018384","descriptor_name":"Oxidative Stress","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D018384","descriptor_name":"Oxidative Stress","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D051267","descriptor_name":"NF-E2-Related Factor 2","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D051267","descriptor_name":"NF-E2-Related Factor 2","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D056945","descriptor_name":"Hep G2 Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D056945","descriptor_name":"Hep G2 Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D056945","descriptor_name":"Hep G2 Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D056945","descriptor_name":"Hep G2 Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059305","descriptor_name":"Diet, High-Fat","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059305","descriptor_name":"Diet, High-Fat","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059305","descriptor_name":"Diet, High-Fat","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D059305","descriptor_name":"Diet, High-Fat","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D065626","descriptor_name":"Non-alcoholic Fatty Liver Disease","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D065626","descriptor_name":"Non-alcoholic Fatty Liver Disease","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D065626","descriptor_name":"Non-alcoholic Fatty Liver Disease","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D065626","descriptor_name":"Non-alcoholic Fatty Liver Disease","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D065626","descriptor_name":"Non-alcoholic Fatty Liver Disease","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D065626","descriptor_name":"Non-alcoholic Fatty Liver Disease","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D065626","descriptor_name":"Non-alcoholic Fatty Liver Disease","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true},{"descriptor_ui":"D065626","descriptor_name":"Non-alcoholic Fatty Liver Disease","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true},{"descriptor_ui":"D065626","descriptor_name":"Non-alcoholic Fatty Liver Disease","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true},{"descriptor_ui":"D065626","descriptor_name":"Non-alcoholic Fatty Liver Disease","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.foodres.2026.118558","doi":"https://doi.org/10.1016/j.foodres.2026.118558","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.foodres.2026.118558","pdf_url":null,"source":{"id":"https://openalex.org/S38919146","display_name":"Food Research International","issn_l":"0963-9969","issn":["0963-9969","1873-7145"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-2","ki-jl-1","medline","norway-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Food Research International","raw_type":"journal-article"},{"id":"pmid:41794448","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/41794448","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Food research international (Ottawa, Ont.)","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9940000176429749}],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G1533532789","display_name":null,"funder_award_id":"32402083","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G2624126405","display_name":"\u9752\u7a1e\u82b1\u8272\u82f7\u57fa\u4e8e\u201c\u80a0-\u809d\u201d\u8f74\u9776\u5411p38 MAPK \u4fe1\u53f7\u901a\u8def\u7f13\u89e3\u809d\u810f\u6162\u6027\u4f4e\u5ea6\u708e\u75c7\u7684\u4f5c\u7528\u53ca\u673a\u5236","funder_award_id":"LQ24C200007","funder_id":"https://openalex.org/F4320338464","funder_display_name":"Natural Science Foundation of Zhejiang Province"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320338464","display_name":"Natural Science Foundation of Zhejiang Province","ror":"https://ror.org/01h0zpd94"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":43,"referenced_works":["https://openalex.org/W2467250481","https://openalex.org/W2800340823","https://openalex.org/W2914892386","https://openalex.org/W2956129408","https://openalex.org/W2979799294","https://openalex.org/W2983752832","https://openalex.org/W3004169316","https://openalex.org/W3004498278","https://openalex.org/W3027118763","https://openalex.org/W3046689344","https://openalex.org/W3047621779","https://openalex.org/W3049097248","https://openalex.org/W3089060810","https://openalex.org/W3108566492","https://openalex.org/W3133638875","https://openalex.org/W4205859368","https://openalex.org/W4214835283","https://openalex.org/W4214883797","https://openalex.org/W4220819827","https://openalex.org/W4225295781","https://openalex.org/W4237074576","https://openalex.org/W4282037658","https://openalex.org/W4285795956","https://openalex.org/W4286512176","https://openalex.org/W4292113795","https://openalex.org/W4293415444","https://openalex.org/W4295898031","https://openalex.org/W4308496455","https://openalex.org/W4327682125","https://openalex.org/W4377141715","https://openalex.org/W4381332100","https://openalex.org/W4382292758","https://openalex.org/W4383999329","https://openalex.org/W4388977867","https://openalex.org/W4391045606","https://openalex.org/W4393074934","https://openalex.org/W4394966089","https://openalex.org/W4396835754","https://openalex.org/W4399022964","https://openalex.org/W4401514467","https://openalex.org/W4401552207","https://openalex.org/W4402042883","https://openalex.org/W4415917507"],"related_works":[],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":3}],"updated_date":"2026-09-27T08:07:27.782135","created_date":"2026-02-03T00:00:00"}