{"id":"https://openalex.org/W7127048383","doi":"https://doi.org/10.1016/j.jcyt.2026.102098","title":"Long-term stability of autologous peripheral blood stem cell products stored for up to 30 years","display_name":"Long-term stability of autologous peripheral blood stem cell products stored for up to 30 years","publication_year":2026,"publication_date":"2026-02-01","ids":{"openalex":"https://openalex.org/W7127048383","doi":"https://doi.org/10.1016/j.jcyt.2026.102098","pmid":"https://pubmed.ncbi.nlm.nih.gov/41916149"},"language":"en","primary_location":{"id":"doi:10.1016/j.jcyt.2026.102098","doi":"https://doi.org/10.1016/j.jcyt.2026.102098","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.jcyt.2026.102098","pdf_url":null,"source":{"id":"https://openalex.org/S36838616","display_name":"Cytotherapy","issn_l":"1465-3249","issn":["1465-3249","1477-2566"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cytotherapy","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5073050097","display_name":"Patrick Tr\u00e9panier","orcid":"https://orcid.org/0000-0002-8645-6230","observed_orcids":["https://orcid.org/0000-0002-8645-6230"]},"institutions":[{"id":"https://openalex.org/I1328242539","display_name":"H\u00e9ma-Qu\u00e9bec","ror":"https://ror.org/008jvv944","country_code":"CA","type":"nonprofit","lineage":["https://openalex.org/I1328242539","https://openalex.org/I2801902503","https://openalex.org/I4210139015"]},{"id":"https://openalex.org/I43406934","display_name":"Universit\u00e9 Laval","ror":"https://ror.org/04sjchr03","country_code":"CA","type":"education","lineage":["https://openalex.org/I43406934"]}],"countries":["CA"],"is_corresponding":true,"raw_author_name":"Patrick Tr\u00e9panier","raw_affiliation_strings":["H\u00e9ma-Qu\u00e9bec, Medical Affairs and Innovation, Quebec City, QC, Canada; Department of Microbiology, Infectious Disease and Immunology, Facult\u00e9 de M\u00e9decine, Universit\u00e9 Laval, Quebec City, QC, Canada. Electronic address: patrick.trepanier@hema-quebec.qc.ca"],"raw_orcid":"https://orcid.org/0000-0002-8645-6230","affiliations":[{"raw_affiliation_string":"H\u00e9ma-Qu\u00e9bec, Medical Affairs and Innovation, Quebec City, QC, Canada; Department of Microbiology, Infectious Disease and Immunology, Facult\u00e9 de M\u00e9decine, Universit\u00e9 Laval, Quebec City, QC, Canada. Electronic address: patrick.trepanier@hema-quebec.qc.ca","institution_ids":["https://openalex.org/I1328242539","https://openalex.org/I43406934"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005724343","display_name":"M. Rh\u00e9aume","orcid":"https://orcid.org/0000-0001-9010-3166","observed_orcids":["https://orcid.org/0000-0001-9010-3166"]},"institutions":[{"id":"https://openalex.org/I1328242539","display_name":"H\u00e9ma-Qu\u00e9bec","ror":"https://ror.org/008jvv944","country_code":"CA","type":"nonprofit","lineage":["https://openalex.org/I1328242539","https://openalex.org/I2801902503","https://openalex.org/I4210139015"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Marie-Eve Rh\u00e9aume","raw_affiliation_strings":["H\u00e9ma-Qu\u00e9bec, Medical Affairs and Innovation, Quebec City, QC, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"H\u00e9ma-Qu\u00e9bec, Medical Affairs and Innovation, Quebec City, QC, Canada","institution_ids":["https://openalex.org/I1328242539"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002825370","display_name":"Carl Simard","orcid":"https://orcid.org/0000-0001-9450-5453","observed_orcids":["https://orcid.org/0000-0001-9450-5453"]},"institutions":[{"id":"https://openalex.org/I1328242539","display_name":"H\u00e9ma-Qu\u00e9bec","ror":"https://ror.org/008jvv944","country_code":"CA","type":"nonprofit","lineage":["https://openalex.org/I1328242539","https://openalex.org/I2801902503","https://openalex.org/I4210139015"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Carl Simard","raw_affiliation_strings":["H\u00e9ma-Qu\u00e9bec, Medical Affairs and Innovation, Quebec City, QC, Canada"],"raw_orcid":"https://orcid.org/0000-0001-9450-5453","affiliations":[{"raw_affiliation_string":"H\u00e9ma-Qu\u00e9bec, Medical Affairs and Innovation, Quebec City, QC, Canada","institution_ids":["https://openalex.org/I1328242539"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001493416","display_name":"Jos\u00e9e Perreault","orcid":"https://orcid.org/0000-0002-9434-2348","observed_orcids":["https://orcid.org/0000-0002-9434-2348"]},"institutions":[{"id":"https://openalex.org/I1328242539","display_name":"H\u00e9ma-Qu\u00e9bec","ror":"https://ror.org/008jvv944","country_code":"CA","type":"nonprofit","lineage":["https://openalex.org/I1328242539","https://openalex.org/I2801902503","https://openalex.org/I4210139015"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Jos\u00e9e Perreault","raw_affiliation_strings":["H\u00e9ma-Qu\u00e9bec, Medical Affairs and Innovation, Quebec City, QC, Canada"],"raw_orcid":"https://orcid.org/0000-0002-9434-2348","affiliations":[{"raw_affiliation_string":"H\u00e9ma-Qu\u00e9bec, Medical Affairs and Innovation, Quebec City, QC, Canada","institution_ids":["https://openalex.org/I1328242539"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Catherine Latour","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1328242539","display_name":"H\u00e9ma-Qu\u00e9bec","ror":"https://ror.org/008jvv944","country_code":"CA","type":"nonprofit","lineage":["https://openalex.org/I1328242539","https://openalex.org/I2801902503","https://openalex.org/I4210139015"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Catherine Latour","raw_affiliation_strings":["H\u00e9ma-Qu\u00e9bec, Transfusion Medicine, Montreal, QC, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"H\u00e9ma-Qu\u00e9bec, Transfusion Medicine, Montreal, QC, Canada","institution_ids":["https://openalex.org/I1328242539"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061923086","display_name":"Marie\u2010Claude Chouinard","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1328242539","display_name":"H\u00e9ma-Qu\u00e9bec","ror":"https://ror.org/008jvv944","country_code":"CA","type":"nonprofit","lineage":["https://openalex.org/I1328242539","https://openalex.org/I2801902503","https://openalex.org/I4210139015"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Marie-Claude Chouinard","raw_affiliation_strings":["H\u00e9ma-Qu\u00e9bec, Transfusion Medicine, Montreal, QC, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"H\u00e9ma-Qu\u00e9bec, Transfusion Medicine, Montreal, QC, Canada","institution_ids":["https://openalex.org/I1328242539"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5033753500","display_name":"Diane Fournier","orcid":"https://orcid.org/0000-0001-9870-4206","observed_orcids":["https://orcid.org/0000-0001-9870-4206"]},"institutions":[{"id":"https://openalex.org/I1328242539","display_name":"H\u00e9ma-Qu\u00e9bec","ror":"https://ror.org/008jvv944","country_code":"CA","type":"nonprofit","lineage":["https://openalex.org/I1328242539","https://openalex.org/I2801902503","https://openalex.org/I4210139015"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Diane Fournier","raw_affiliation_strings":["H\u00e9ma-Qu\u00e9bec, Transfusion Medicine, Montreal, QC, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"H\u00e9ma-Qu\u00e9bec, Transfusion Medicine, Montreal, QC, Canada","institution_ids":["https://openalex.org/I1328242539"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5073050097"],"corresponding_institution_ids":["https://openalex.org/I1328242539","https://openalex.org/I43406934"],"apc_list":{"value":3300,"currency":"USD","value_usd":3300},"apc_paid":null,"fwci":3.7298,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.86245353,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":91,"max":95},"biblio":{"volume":"28","issue":"6","first_page":"102098","last_page":"102098"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10345","display_name":"Hematopoietic Stem Cell Transplantation","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10345","display_name":"Hematopoietic Stem Cell Transplantation","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10693","display_name":"Blood transfusion and management","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10176","display_name":"Mesenchymal stem cell research","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/autologous-peripheral-blood-stem-cells","display_name":"autologous peripheral blood stem cells","score":0.9639999866485596},{"id":"https://openalex.org/keywords/long-term-cryopreservation","display_name":"long-term cryopreservation","score":0.8550000190734863},{"id":"https://openalex.org/keywords/clonogenicity","display_name":"clonogenicity","score":0.9959999918937683},{"id":"https://openalex.org/keywords/stat5-phosphorylation","display_name":"STAT5 phosphorylation","score":0.8560000061988831},{"id":"https://openalex.org/keywords/colony-forming-units","display_name":"colony-forming units","score":0.8169999718666077},{"id":"https://openalex.org/keywords/multiple-myeloma","display_name":"multiple myeloma","score":0.7720000147819519}],"concepts":[{"id":"https://openalex.org/C117262875","wikidata":"https://www.wikidata.org/wiki/Q5135057","display_name":"Clonogenic assay","level":3,"score":0.7944999933242798},{"id":"https://openalex.org/C179933525","wikidata":"https://www.wikidata.org/wiki/Q1144664","display_name":"Cryopreservation","level":3,"score":0.7190999984741211},{"id":"https://openalex.org/C28328180","wikidata":"https://www.wikidata.org/wiki/Q48196","display_name":"Stem cell","level":2,"score":0.6823999881744385},{"id":"https://openalex.org/C16685009","wikidata":"https://www.wikidata.org/wiki/Q335057","display_name":"Andrology","level":1,"score":0.52920001745224},{"id":"https://openalex.org/C53227056","wikidata":"https://www.wikidata.org/wiki/Q189152","display_name":"Viability assay","level":3,"score":0.5116000175476074},{"id":"https://openalex.org/C2909265885","wikidata":"https://www.wikidata.org/wiki/Q2329938","display_name":"Peripheral Blood Stem Cells","level":4,"score":0.4596000015735626},{"id":"https://openalex.org/C2777396833","wikidata":"https://www.wikidata.org/wiki/Q886722","display_name":"Blood product","level":2,"score":0.4262000024318695},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4171000123023987},{"id":"https://openalex.org/C2988529969","wikidata":"https://www.wikidata.org/wiki/Q5142478","display_name":"Cold storage","level":2,"score":0.38260000944137573},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.36340001225471497},{"id":"https://openalex.org/C3017910909","wikidata":"https://www.wikidata.org/wiki/Q618363","display_name":"Peripheral blood","level":2,"score":0.32499998807907104},{"id":"https://openalex.org/C90673727","wikidata":"https://www.wikidata.org/wiki/Q901718","display_name":"Product (mathematics)","level":2,"score":0.3240000009536743},{"id":"https://openalex.org/C29537977","wikidata":"https://www.wikidata.org/wiki/Q188941","display_name":"Cell cycle","level":3,"score":0.3102000057697296},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.296099990606308},{"id":"https://openalex.org/C1621761","wikidata":"https://www.wikidata.org/wiki/Q7997549","display_name":"Whole blood","level":2,"score":0.2921999990940094},{"id":"https://openalex.org/C2776738589","wikidata":"https://www.wikidata.org/wiki/Q618446","display_name":"Apheresis","level":3,"score":0.2921000123023987},{"id":"https://openalex.org/C2779979121","wikidata":"https://www.wikidata.org/wiki/Q211709","display_name":"Blood cell","level":2,"score":0.29179999232292175},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.2831999957561493},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.2827000021934509},{"id":"https://openalex.org/C3019433047","wikidata":"https://www.wikidata.org/wiki/Q379071","display_name":"Autologous blood","level":2,"score":0.2793999910354614},{"id":"https://openalex.org/C10882517","wikidata":"https://www.wikidata.org/wiki/Q15268054","display_name":"Cell therapy","level":3,"score":0.2667999863624573},{"id":"https://openalex.org/C72563966","wikidata":"https://www.wikidata.org/wiki/Q1303415","display_name":"Cohort","level":2,"score":0.26330000162124634},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2624000012874603},{"id":"https://openalex.org/C2777371436","wikidata":"https://www.wikidata.org/wiki/Q3237071","display_name":"Leukapheresis","level":4,"score":0.2583000063896179},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.2574000060558319},{"id":"https://openalex.org/C198826908","wikidata":"https://www.wikidata.org/wiki/Q1922379","display_name":"Mesenchymal stem cell","level":2,"score":0.2551000118255615}],"mesh":[{"descriptor_ui":"D000072916","descriptor_name":"Peripheral Blood Stem Cells","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":true},{"descriptor_ui":"D000072916","descriptor_name":"Peripheral Blood Stem Cells","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D002470","descriptor_name":"Cell Survival","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007377","descriptor_name":"Interleukin-3","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014182","descriptor_name":"Transplantation, Autologous","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015925","descriptor_name":"Cryopreservation","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D018952","descriptor_name":"Antigens, CD34","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D036102","descriptor_name":"Peripheral Blood Stem Cell Transplantation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D050799","descriptor_name":"STAT5 Transcription Factor","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.jcyt.2026.102098","doi":"https://doi.org/10.1016/j.jcyt.2026.102098","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.jcyt.2026.102098","pdf_url":null,"source":{"id":"https://openalex.org/S36838616","display_name":"Cytotherapy","issn_l":"1465-3249","issn":["1465-3249","1477-2566"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cytotherapy","raw_type":"journal-article"},{"id":"pmid:41916149","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/41916149","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cytotherapy","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9391000270843506,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320334618","display_name":"Fonds de Recherche du Qu\u00e9bec - Sant\u00e9","ror":"https://ror.org/02eqrsj93"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":14,"referenced_works":["https://openalex.org/W1674932451","https://openalex.org/W1972016720","https://openalex.org/W2010055592","https://openalex.org/W2080401012","https://openalex.org/W2083883875","https://openalex.org/W2161959128","https://openalex.org/W2432465707","https://openalex.org/W2562072897","https://openalex.org/W2998012061","https://openalex.org/W3016811297","https://openalex.org/W3032048939","https://openalex.org/W3185672235","https://openalex.org/W4221137077","https://openalex.org/W4223494178"],"related_works":["https://openalex.org/W3185672235","https://openalex.org/W2106603154","https://openalex.org/W2010466691","https://openalex.org/W7214808526","https://openalex.org/W1513835762","https://openalex.org/W2032426397","https://openalex.org/W2001197808","https://openalex.org/W7126392145","https://openalex.org/W2562072897","https://openalex.org/W4380291499"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2026-02-03T00:00:00"}