{"id":"https://openalex.org/W7127040777","doi":"https://doi.org/10.1016/j.jgar.2026.01.011","title":"Clinical efficacy of trimethoprim-sulfamethoxazole treatment for pediatric pertussis in macrolide-resistant endemic regions: A retrospective cohort study","display_name":"Clinical efficacy of trimethoprim-sulfamethoxazole treatment for pediatric pertussis in macrolide-resistant endemic regions: A retrospective cohort study","publication_year":2026,"publication_date":"2026-02-01","ids":{"openalex":"https://openalex.org/W7127040777","doi":"https://doi.org/10.1016/j.jgar.2026.01.011","pmid":"https://pubmed.ncbi.nlm.nih.gov/41628688"},"language":"en","primary_location":{"id":"doi:10.1016/j.jgar.2026.01.011","doi":"https://doi.org/10.1016/j.jgar.2026.01.011","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.jgar.2026.01.011","pdf_url":null,"source":{"id":"https://openalex.org/S2764745279","display_name":"Journal of Global Antimicrobial Resistance","issn_l":"2213-7165","issn":["2213-7165","2213-7173"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-40","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Global Antimicrobial Resistance","raw_type":"journal-article"},"parent_works":[],"lineage":["https://openalex.org/W7127040777"],"child_works_count":0,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1016/j.jgar.2026.01.011","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5124712116","display_name":"Juan Yuan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210142339","display_name":"Xi\u2019an Children\u2019s Hospital","ror":"https://ror.org/04595zj73","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210142339"]},{"id":"https://openalex.org/I87445476","display_name":"Xi'an Jiaotong University","ror":"https://ror.org/017zhmm22","country_code":"CN","type":"education","lineage":["https://openalex.org/I87445476"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Juan Yuan","raw_affiliation_strings":["Department of Infection, Xi'an Children's Hospital, Affiliated Children's Hospital of Xi'an Jiaotong University, National Regional Children's Medical Center (Northwest), Xi'an, Shaanxi, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Infection, Xi'an Children's Hospital, Affiliated Children's Hospital of Xi'an Jiaotong University, National Regional Children's Medical Center (Northwest), Xi'an, Shaanxi, China","institution_ids":["https://openalex.org/I4210142339","https://openalex.org/I87445476"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043184341","display_name":"Yarong Yang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210142339","display_name":"Xi\u2019an Children\u2019s Hospital","ror":"https://ror.org/04595zj73","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210142339"]},{"id":"https://openalex.org/I87445476","display_name":"Xi'an Jiaotong University","ror":"https://ror.org/017zhmm22","country_code":"CN","type":"education","lineage":["https://openalex.org/I87445476"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yarong Yang","raw_affiliation_strings":["Department of Infection, Xi'an Children's Hospital, Affiliated Children's Hospital of Xi'an Jiaotong University, National Regional Children's Medical Center (Northwest), Xi'an, Shaanxi, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Infection, Xi'an Children's Hospital, Affiliated Children's Hospital of Xi'an Jiaotong University, National Regional Children's Medical Center (Northwest), Xi'an, Shaanxi, China","institution_ids":["https://openalex.org/I4210142339","https://openalex.org/I87445476"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5124746947","display_name":"Yi Zhang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210142339","display_name":"Xi\u2019an Children\u2019s Hospital","ror":"https://ror.org/04595zj73","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210142339"]},{"id":"https://openalex.org/I87445476","display_name":"Xi'an Jiaotong University","ror":"https://ror.org/017zhmm22","country_code":"CN","type":"education","lineage":["https://openalex.org/I87445476"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yi Zhang","raw_affiliation_strings":["Department of Infection, Xi'an Children's Hospital, Affiliated Children's Hospital of Xi'an Jiaotong University, National Regional Children's Medical Center (Northwest), Xi'an, Shaanxi, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Infection, Xi'an Children's Hospital, Affiliated Children's Hospital of Xi'an Jiaotong University, National Regional Children's Medical Center (Northwest), Xi'an, Shaanxi, China","institution_ids":["https://openalex.org/I4210142339","https://openalex.org/I87445476"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5124742677","display_name":"Jun Wang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210142339","display_name":"Xi\u2019an Children\u2019s Hospital","ror":"https://ror.org/04595zj73","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210142339"]},{"id":"https://openalex.org/I87445476","display_name":"Xi'an Jiaotong University","ror":"https://ror.org/017zhmm22","country_code":"CN","type":"education","lineage":["https://openalex.org/I87445476"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jun Wang","raw_affiliation_strings":["Department of Infection, Xi'an Children's Hospital, Affiliated Children's Hospital of Xi'an Jiaotong University, National Regional Children's Medical Center (Northwest), Xi'an, Shaanxi, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Infection, Xi'an Children's Hospital, Affiliated Children's Hospital of Xi'an Jiaotong University, National Regional Children's Medical Center (Northwest), Xi'an, Shaanxi, China","institution_ids":["https://openalex.org/I4210142339","https://openalex.org/I87445476"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5124719602","display_name":"Bin Xue","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210142339","display_name":"Xi\u2019an Children\u2019s Hospital","ror":"https://ror.org/04595zj73","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210142339"]},{"id":"https://openalex.org/I87445476","display_name":"Xi'an Jiaotong University","ror":"https://ror.org/017zhmm22","country_code":"CN","type":"education","lineage":["https://openalex.org/I87445476"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Bin Xue","raw_affiliation_strings":["Department of Infection, Xi'an Children's Hospital, Affiliated Children's Hospital of Xi'an Jiaotong University, National Regional Children's Medical Center (Northwest), Xi'an, Shaanxi, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Infection, Xi'an Children's Hospital, Affiliated Children's Hospital of Xi'an Jiaotong University, National Regional Children's Medical Center (Northwest), Xi'an, Shaanxi, China","institution_ids":["https://openalex.org/I4210142339","https://openalex.org/I87445476"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5124721423","display_name":"Fangzhi He","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210142339","display_name":"Xi\u2019an Children\u2019s Hospital","ror":"https://ror.org/04595zj73","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210142339"]},{"id":"https://openalex.org/I87445476","display_name":"Xi'an Jiaotong University","ror":"https://ror.org/017zhmm22","country_code":"CN","type":"education","lineage":["https://openalex.org/I87445476"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Fangzhi He","raw_affiliation_strings":["Department of Infection, Xi'an Children's Hospital, Affiliated Children's Hospital of Xi'an Jiaotong University, National Regional Children's Medical Center (Northwest), Xi'an, Shaanxi, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Infection, Xi'an Children's Hospital, Affiliated Children's Hospital of Xi'an Jiaotong University, National Regional Children's Medical Center (Northwest), Xi'an, Shaanxi, China","institution_ids":["https://openalex.org/I4210142339","https://openalex.org/I87445476"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5124700275","display_name":"Wenjuan Zhao","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I75920027","display_name":"Shaanxi University of Chinese Medicine","ror":"https://ror.org/021r98132","country_code":"CN","type":"education","lineage":["https://openalex.org/I75920027"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wenjuan Zhao","raw_affiliation_strings":["Shaanxi University of Chinese Medicine, Xianyang, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shaanxi University of Chinese Medicine, Xianyang, China","institution_ids":["https://openalex.org/I75920027"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103555597","display_name":"Shuyue Tang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I75920027","display_name":"Shaanxi University of Chinese Medicine","ror":"https://ror.org/021r98132","country_code":"CN","type":"education","lineage":["https://openalex.org/I75920027"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shuyue Tang","raw_affiliation_strings":["Shaanxi University of Chinese Medicine, Xianyang, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shaanxi University of Chinese Medicine, Xianyang, China","institution_ids":["https://openalex.org/I75920027"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5130636655","display_name":"Zengguo Wang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210142339","display_name":"Xi\u2019an Children\u2019s Hospital","ror":"https://ror.org/04595zj73","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210142339"]},{"id":"https://openalex.org/I75920027","display_name":"Shaanxi University of Chinese Medicine","ror":"https://ror.org/021r98132","country_code":"CN","type":"education","lineage":["https://openalex.org/I75920027"]},{"id":"https://openalex.org/I87445476","display_name":"Xi'an Jiaotong University","ror":"https://ror.org/017zhmm22","country_code":"CN","type":"education","lineage":["https://openalex.org/I87445476"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zengguo Wang","raw_affiliation_strings":["Shaanxi University of Chinese Medicine, Xianyang, China; Department of Clinical Laboratory, Xi'an Children's Hospital, Affiliated Children's Hospital of Xi'an Jiaotong University, National Regional Children's Medical Center (Northwest), Xi'an, Shaanxi, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shaanxi University of Chinese Medicine, Xianyang, China; Department of Clinical Laboratory, Xi'an Children's Hospital, Affiliated Children's Hospital of Xi'an Jiaotong University, National Regional Children's Medical Center (Northwest), Xi'an, Shaanxi, China","institution_ids":["https://openalex.org/I4210142339","https://openalex.org/I75920027","https://openalex.org/I87445476"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5103903684","display_name":"Xinxin Zhu","orcid":"https://orcid.org/0000-0001-9275-2709","observed_orcids":["https://orcid.org/0000-0001-9275-2709"]},"institutions":[{"id":"https://openalex.org/I4210142339","display_name":"Xi\u2019an Children\u2019s Hospital","ror":"https://ror.org/04595zj73","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210142339"]},{"id":"https://openalex.org/I87445476","display_name":"Xi'an Jiaotong University","ror":"https://ror.org/017zhmm22","country_code":"CN","type":"education","lineage":["https://openalex.org/I87445476"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Xinxin Zhu","raw_affiliation_strings":["Department of Infection, Xi'an Children's Hospital, Affiliated Children's Hospital of Xi'an Jiaotong University, National Regional Children's Medical Center (Northwest), Xi'an, Shaanxi, China. Electronic address: why1986818@163.com"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Infection, Xi'an Children's Hospital, Affiliated Children's Hospital of Xi'an Jiaotong University, National Regional Children's Medical Center (Northwest), Xi'an, Shaanxi, China. Electronic address: why1986818@163.com","institution_ids":["https://openalex.org/I4210142339","https://openalex.org/I87445476"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5103903684"],"corresponding_institution_ids":["https://openalex.org/I4210142339","https://openalex.org/I87445476"],"apc_list":{"value":1890,"currency":"USD","value_usd":1890},"apc_paid":{"value":1890,"currency":"USD","value_usd":1890},"fwci":2.9867,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.82711789,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":91,"max":95},"biblio":{"volume":"47","issue":null,"first_page":"33","last_page":"37"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10873","display_name":"Bacterial Infections and Vaccines","score":0.9955999851226807,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10873","display_name":"Bacterial Infections and Vaccines","score":0.9955999851226807,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11688","display_name":"Microbial infections and disease research","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12499","display_name":"Diphtheria, Corynebacterium, and Tetanus","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/trimethoprim-sulfamethoxazole","display_name":"trimethoprim-sulfamethoxazole","score":0.9120000004768372},{"id":"https://openalex.org/keywords/macrolide-resistance","display_name":"macrolide resistance","score":0.8489999771118164},{"id":"https://openalex.org/keywords/treatment-duration","display_name":"treatment duration","score":0.7419999837875366},{"id":"https://openalex.org/keywords/clinical-remission","display_name":"clinical remission","score":0.9750000238418579},{"id":"https://openalex.org/keywords/adverse-drug-reactions","display_name":"adverse drug reactions","score":0.6949999928474426},{"id":"https://openalex.org/keywords/skin-lesions","display_name":"skin lesions","score":0.8659999966621399},{"id":"https://openalex.org/keywords/treatment-efficacy","display_name":"treatment efficacy","score":0.45500001311302185}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8655999898910522},{"id":"https://openalex.org/C167135981","wikidata":"https://www.wikidata.org/wiki/Q2146302","display_name":"Retrospective cohort study","level":2,"score":0.7678999900817871},{"id":"https://openalex.org/C2992053201","wikidata":"https://www.wikidata.org/wiki/Q2585693","display_name":"Clinical efficacy","level":2,"score":0.7214000225067139},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.5357000231742859},{"id":"https://openalex.org/C197934379","wikidata":"https://www.wikidata.org/wiki/Q2047938","display_name":"Adverse effect","level":2,"score":0.48649999499320984},{"id":"https://openalex.org/C201903717","wikidata":"https://www.wikidata.org/wiki/Q1778788","display_name":"Cohort study","level":2,"score":0.4781999886035919},{"id":"https://openalex.org/C72563966","wikidata":"https://www.wikidata.org/wiki/Q1303415","display_name":"Cohort","level":2,"score":0.39899998903274536},{"id":"https://openalex.org/C535046627","wikidata":"https://www.wikidata.org/wiki/Q30612","display_name":"Clinical trial","level":2,"score":0.3246999979019165},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.31060001254081726},{"id":"https://openalex.org/C2779473830","wikidata":"https://www.wikidata.org/wiki/Q1540899","display_name":"MEDLINE","level":2,"score":0.30640000104904175},{"id":"https://openalex.org/C107130276","wikidata":"https://www.wikidata.org/wiki/Q133805","display_name":"Epidemiology","level":2,"score":0.2915000021457672},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.2743000090122223},{"id":"https://openalex.org/C195910791","wikidata":"https://www.wikidata.org/wiki/Q1324077","display_name":"Medical record","level":2,"score":0.2741999924182892},{"id":"https://openalex.org/C205545832","wikidata":"https://www.wikidata.org/wiki/Q17156455","display_name":"Young adult","level":2,"score":0.2596000134944916},{"id":"https://openalex.org/C188816634","wikidata":"https://www.wikidata.org/wiki/Q2113324","display_name":"Prospective cohort study","level":2,"score":0.25619998574256897}],"mesh":[{"descriptor_ui":"D000900","descriptor_name":"Anti-Bacterial Agents","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D000900","descriptor_name":"Anti-Bacterial Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D001886","descriptor_name":"Bordetella pertussis","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D001886","descriptor_name":"Bordetella pertussis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002675","descriptor_name":"Child, Preschool","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007223","descriptor_name":"Infant","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014917","descriptor_name":"Whooping Cough","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D014917","descriptor_name":"Whooping Cough","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":true},{"descriptor_ui":"D014917","descriptor_name":"Whooping Cough","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D015662","descriptor_name":"Trimethoprim, Sulfamethoxazole Drug Combination","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D015662","descriptor_name":"Trimethoprim, Sulfamethoxazole Drug Combination","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D015662","descriptor_name":"Trimethoprim, Sulfamethoxazole Drug Combination","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018942","descriptor_name":"Macrolides","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D024881","descriptor_name":"Drug Resistance, Bacterial","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.jgar.2026.01.011","doi":"https://doi.org/10.1016/j.jgar.2026.01.011","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.jgar.2026.01.011","pdf_url":null,"source":{"id":"https://openalex.org/S2764745279","display_name":"Journal of Global Antimicrobial Resistance","issn_l":"2213-7165","issn":["2213-7165","2213-7173"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-40","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Global Antimicrobial Resistance","raw_type":"journal-article"},{"id":"pmid:41628688","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/41628688","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of global antimicrobial resistance","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1016/j.jgar.2026.01.011","doi":"https://doi.org/10.1016/j.jgar.2026.01.011","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.jgar.2026.01.011","pdf_url":null,"source":{"id":"https://openalex.org/S2764745279","display_name":"Journal of Global Antimicrobial Resistance","issn_l":"2213-7165","issn":["2213-7165","2213-7173"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-40","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Global Antimicrobial Resistance","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[{"id":"https://openalex.org/G6570770271","display_name":null,"funder_award_id":"82172312","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":14,"referenced_works":["https://openalex.org/W1968374680","https://openalex.org/W2021994586","https://openalex.org/W2104473737","https://openalex.org/W2626528754","https://openalex.org/W2800775622","https://openalex.org/W2889939745","https://openalex.org/W2914144052","https://openalex.org/W2917324881","https://openalex.org/W4399840958","https://openalex.org/W4401264466","https://openalex.org/W4404365457","https://openalex.org/W4404776994","https://openalex.org/W4404991004","https://openalex.org/W4405116119"],"related_works":["https://openalex.org/W4417146060","https://openalex.org/W7165961479","https://openalex.org/W7119612199","https://openalex.org/W4413770802","https://openalex.org/W4408335096","https://openalex.org/W4389031068","https://openalex.org/W2914144052","https://openalex.org/W7118172560","https://openalex.org/W3113207127","https://openalex.org/W7118951650"],"abstract_inverted_index":{"OBJECTIVE:":[0],"To":[1],"assess":[2],"the":[3,134,137,173,237],"efficacy":[4,221],"and":[5,51,64,101,154],"influencing":[6],"factors":[7],"of":[8,21,29,67,121,144,197],"sulfamethoxazole-trimethoprim":[9],"(SXT)":[10],"in":[11,15,199,201],"children":[12,200],"with":[13,17,36,179],"pertussis":[14,24,33,198],"regions":[16],"a":[18,118,223],"high":[19,202],"prevalence":[20,204],"macrolide-resistant":[22],"Bordetella":[23],"(MRBP).":[25],"METHODS:":[26],"A":[27],"total":[28],"317":[30],"PCR-confirmed":[31],"pediatric":[32],"cases":[34],"treated":[35],"SXT":[37,80,88,192,215],"were":[38,42,70,168,172,232,236],"retrospectively":[39],"analyzed.":[40,71],"Patients":[41],"categorized":[43],"into":[44],"short-term":[45],"(5-7":[46,226],"days,":[47,54],"n":[48,55],"=":[49,56,152,162,189],"93)":[50],"long-term":[52],"(10-14":[53,217],"65)":[57],"treatment":[58,68],"groups.":[59],"Clinical":[60],"outcomes,":[61],"adverse":[62,166,176,230],"events,":[63],"potential":[65],"predictors":[66],"response":[69],"RESULTS:":[72],"The":[73],"median":[74],"interval":[75],"from":[76],"symptom":[77],"onset":[78],"to":[79,133,222],"initiation":[81],"was":[82],"12":[83],"days":[84],"(IQR:":[85],"9-15).":[86],"Following":[87],"therapy,":[89],"243":[90],"patients":[91],"(76.7%)":[92],"achieved":[93],"clinical":[94,108,122,146,195,211],"remission,":[95],"68":[96],"(21.4%)":[97],"showed":[98],"partial":[99],"improvement,":[100],"6":[102],"(1.9%)":[103],"experienced":[104],"no":[105,180],"relief,":[106],"without":[107],"deterioration.":[109],"Multivariate":[110],"analysis":[111],"identified":[112],"nucleic":[113,155],"acid":[114,156,207],"negative":[115,208],"conversion":[116,209],"as":[117],"independent":[119],"predictor":[120],"remission":[123,147],"(OR,":[124],"5.14,":[125],"95%":[126],"CI:":[127],"2.66-9.88,":[128],"p":[129,151,161,188],"<":[130],"0.001).":[131],"Compared":[132],"short-course":[135],"group,":[136],"long-course":[138],"group":[139],"demonstrated":[140],"significantly":[141],"higher":[142],"rates":[143],"both":[145],"(83.1%":[148],"vs.":[149,159,186],"66.7%,":[150],"0.022)":[153],"clearance":[157],"(87.7%":[158],"71.0%,":[160],"0.013).":[163],"No":[164,228],"serious":[165,229],"events":[167,177,231],"reported.":[169],"Skin":[170],"lesions":[171,235],"most":[174,238],"frequent":[175],"(5.1%),":[178],"significant":[181],"difference":[182],"between":[183],"groups":[184],"(3.2%":[185],"7.7%,":[187],"0.373).":[190],"CONCLUSIONS:":[191],"effectively":[193],"alleviates":[194],"symptoms":[196],"MRBP":[203],"regions.":[205],"Nucleic":[206],"predicts":[210],"remission.":[212],"An":[213],"extended":[214],"course":[216,225],"days)":[218],"demonstrates":[219],"superior":[220],"shorter":[224],"days).":[227],"observed;":[233],"skin":[234],"common":[239],"side":[240],"effect.":[241]},"counts_by_year":[{"year":2026,"cited_by_count":1}],"updated_date":"2026-11-13T13:42:25.865203","created_date":"2026-02-03T00:00:00"}