{"id":"https://openalex.org/W7127039704","doi":"https://doi.org/10.51891/rease.v12i1.23967","title":"ADAPTA\u00c7\u00c3O, PERSIST\u00caNCIA E RESIST\u00caNCIA ANTIMICROBIANA DE PSEUDOMONAS AERUGINOSA NO AMBIENTE HOSPITALAR","display_name":"ADAPTA\u00c7\u00c3O, PERSIST\u00caNCIA E RESIST\u00caNCIA ANTIMICROBIANA DE PSEUDOMONAS AERUGINOSA NO AMBIENTE HOSPITALAR","publication_year":2026,"publication_date":"2026-01-30","ids":{"openalex":"https://openalex.org/W7127039704","doi":"https://doi.org/10.51891/rease.v12i1.23967"},"language":"pt","primary_location":{"id":"doi:10.51891/rease.v12i1.23967","doi":"https://doi.org/10.51891/rease.v12i1.23967","is_oa":true,"landing_page_url":"https://doi.org/10.51891/rease.v12i1.23967","pdf_url":"https://periodicorease.pro.br/rease/article/download/23967/15184","source":{"id":"https://openalex.org/S4210238184","display_name":"Revista Ibero-Americana de Humanidades, Ci\u00eancias e Educa\u00e7\u00e3o","issn_l":"2675-3375","issn":["2675-3375"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4365394759","host_organization_name":"Arche Scientific and Editorial Consultancy","host_organization_lineage":["https://openalex.org/P4365394759"],"host_organization_lineage_names":["Arche Scientific and Editorial Consultancy"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Revista Ibero-Americana de Humanidades, Ci\u00eancias e Educa\u00e7\u00e3o","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://periodicorease.pro.br/rease/article/download/23967/15184","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5124711733","display_name":"Lucas dos Santos Sa","orcid":"https://orcid.org/0009-0006-8814-216X","observed_orcids":["https://orcid.org/0009-0006-8814-216X"]},"institutions":[{"id":"https://openalex.org/I4210136434","display_name":"Faculdade \u00danica","ror":"https://ror.org/03gf7q691","country_code":"BR","type":"education","lineage":["https://openalex.org/I4210136434"]}],"countries":["BR"],"is_corresponding":true,"raw_author_name":"Lucas dos Santos Sa","raw_affiliation_strings":["Faculdade \u00danica"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculdade \u00danica","institution_ids":["https://openalex.org/I4210136434"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5124711733"],"corresponding_institution_ids":["https://openalex.org/I4210136434"],"apc_list":null,"apc_paid":null,"fwci":1.3024,"has_fulltext":true,"cited_by_count":1,"citation_normalized_percentile":{"value":0.71682836,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":91,"max":95},"biblio":{"volume":"12","issue":"1","first_page":"1","last_page":"14"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10593","display_name":"Bacterial biofilms and quorum sensing","score":0.8925999999046326,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10593","display_name":"Bacterial biofilms and quorum sensing","score":0.8925999999046326,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10147","display_name":"Antibiotic Resistance in Bacteria","score":0.08579999953508377,"subfield":{"id":"https://openalex.org/subfields/2726","display_name":"Microbiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12824","display_name":"Infections and bacterial resistance","score":0.008799999952316284,"subfield":{"id":"https://openalex.org/subfields/2726","display_name":"Microbiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pseudomonas-aeruginosa","display_name":"Pseudomonas aeruginosa","score":1.0},{"id":"https://openalex.org/keywords/antimicrobial-resistance","display_name":"antimicrobial resistance","score":0.9729999899864197},{"id":"https://openalex.org/keywords/multidrug-resistance","display_name":"multidrug resistance","score":0.7789999842643738},{"id":"https://openalex.org/keywords/biofilm","display_name":"biofilm","score":0.9160000085830688},{"id":"https://openalex.org/keywords/hospital-environment","display_name":"hospital environment","score":0.7009999752044678},{"id":"https://openalex.org/keywords/nosocomial-infections","display_name":"nosocomial infections","score":0.8059999942779541},{"id":"https://openalex.org/keywords/opportunistic-pathogens","display_name":"opportunistic pathogens","score":0.5870000123977661},{"id":"https://openalex.org/keywords/beta-lactamase","display_name":"beta-lactamase","score":0.8130000233650208},{"id":"https://openalex.org/keywords/efflux-pumps","display_name":"efflux pumps","score":0.9919999837875366},{"id":"https://openalex.org/keywords/lipopolysaccharide-modification","display_name":"lipopolysaccharide modification","score":0.7689999938011169},{"id":"https://openalex.org/keywords/bacterial-persistence","display_name":"bacterial persistence","score":0.5249999761581421},{"id":"https://openalex.org/keywords/environmental-adaptation","display_name":"environmental adaptation","score":0.3790000081062317}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4359999895095825},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3091999888420105},{"id":"https://openalex.org/C2777637488","wikidata":"https://www.wikidata.org/wiki/Q31856","display_name":"Pseudomonas aeruginosa","level":3,"score":0.3052000105381012},{"id":"https://openalex.org/C15708023","wikidata":"https://www.wikidata.org/wiki/Q80083","display_name":"Humanities","level":1,"score":0.2793000042438507},{"id":"https://openalex.org/C3020434087","wikidata":"https://www.wikidata.org/wiki/Q835718","display_name":"Opportunistic pathogen","level":4,"score":0.25},{"id":"https://openalex.org/C17744445","wikidata":"https://www.wikidata.org/wiki/Q36442","display_name":"Political science","level":0,"score":0.2085999995470047},{"id":"https://openalex.org/C205649164","wikidata":"https://www.wikidata.org/wiki/Q1071","display_name":"Geography","level":0,"score":0.19020000100135803},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.18770000338554382},{"id":"https://openalex.org/C2909960733","wikidata":"https://www.wikidata.org/wiki/Q68541106","display_name":"Antimicrobial drug","level":3,"score":0.1875},{"id":"https://openalex.org/C94665300","wikidata":"https://www.wikidata.org/wiki/Q63391344","display_name":"Antibiotic resistance","level":3,"score":0.17059999704360962}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.51891/rease.v12i1.23967","doi":"https://doi.org/10.51891/rease.v12i1.23967","is_oa":true,"landing_page_url":"https://doi.org/10.51891/rease.v12i1.23967","pdf_url":"https://periodicorease.pro.br/rease/article/download/23967/15184","source":{"id":"https://openalex.org/S4210238184","display_name":"Revista Ibero-Americana de Humanidades, Ci\u00eancias e Educa\u00e7\u00e3o","issn_l":"2675-3375","issn":["2675-3375"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4365394759","host_organization_name":"Arche Scientific and Editorial Consultancy","host_organization_lineage":["https://openalex.org/P4365394759"],"host_organization_lineage_names":["Arche Scientific and Editorial Consultancy"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Revista Ibero-Americana de Humanidades, Ci\u00eancias e Educa\u00e7\u00e3o","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.51891/rease.v12i1.23967","doi":"https://doi.org/10.51891/rease.v12i1.23967","is_oa":true,"landing_page_url":"https://doi.org/10.51891/rease.v12i1.23967","pdf_url":"https://periodicorease.pro.br/rease/article/download/23967/15184","source":{"id":"https://openalex.org/S4210238184","display_name":"Revista Ibero-Americana de Humanidades, Ci\u00eancias e Educa\u00e7\u00e3o","issn_l":"2675-3375","issn":["2675-3375"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4365394759","host_organization_name":"Arche Scientific and Editorial Consultancy","host_organization_lineage":["https://openalex.org/P4365394759"],"host_organization_lineage_names":["Arche Scientific and Editorial Consultancy"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Revista Ibero-Americana de Humanidades, Ci\u00eancias e Educa\u00e7\u00e3o","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9476000070571899,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7127039704.pdf","grobid_xml":"https://content.openalex.org/works/W7127039704.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W3201447394","https://openalex.org/W4415067942","https://openalex.org/W4405039319","https://openalex.org/W4405905578","https://openalex.org/W4226227553","https://openalex.org/W7120783959","https://openalex.org/W4392892917","https://openalex.org/W4406238643","https://openalex.org/W1927914165","https://openalex.org/W7094040129"],"abstract_inverted_index":{"Pseudomonas":[0,181],"aeruginosa":[1,95],"\u00e9":[2],"um":[3,14],"bacilo":[4],"Gram-negativo":[5],"oportunista":[6],"amplamente":[7],"distribu\u00eddo":[8],"no":[9,131],"ambiente":[10],"e":[11,56,66,88,108,129,143,155,165,176,196,206,212],"reconhecido":[12],"como":[13,184],"dos":[15,91],"principais":[16,168],"agentes":[17],"etiol\u00f3gicos":[18],"de":[19,42,47,54,58,61,69,83,102,105,112,115,125,127,162,170,180,191,193,201],"infec\u00e7\u00f5es":[20,153],"associadas":[21],"\u00e0":[22,24],"assist\u00eancia":[23],"sa\u00fade,":[25],"especialmente":[26],"em":[27,49,80,136,214],"pacientes":[28],"imunocomprometidos":[29],"ou":[30],"submetidos":[31],"a":[32,99,134,145,177,188,203],"procedimentos":[33],"invasivos.":[34],"Sua":[35],"relev\u00e2ncia":[36],"cl\u00ednica":[37],"decorre":[38],"da":[39,119,121],"combina\u00e7\u00e3o":[40],"singular":[41],"elevada":[43,139],"adaptabilidade":[44],"metab\u00f3lica,":[45],"capacidade":[46],"persist\u00eancia":[48],"ambientes":[50],"hospitalares,":[51],"forma\u00e7\u00e3o":[52],"robusta":[53],"biofilmes":[55,137],"express\u00e3o":[57],"m\u00faltiplos":[59],"mecanismos":[60,106,169],"resist\u00eancia":[62,97,171,204],"antimicrobiana.":[63],"A":[64],"emerg\u00eancia":[65],"dissemina\u00e7\u00e3o":[67],"global":[68],"cepas":[70],"multirresistentes":[71,211],"t\u00eam":[72],"reduzido":[73],"drasticamente":[74],"as":[75],"op\u00e7\u00f5es":[76],"terap\u00eauticas":[77,86,198],"dispon\u00edveis,":[78],"resultando":[79],"altas":[81],"taxas":[82],"morbimortalidade,":[84],"falhas":[85],"recorrentes":[87],"aumento":[89],"significativo":[90],"custos":[92],"hospitalares.":[93],"P.":[94],"apresenta":[96],"intr\u00ednseca":[98],"diversas":[100],"classes":[101],"antibi\u00f3ticos,":[103],"al\u00e9m":[104],"adquiridos":[107],"adaptativos,":[109],"incluindo":[110],"produ\u00e7\u00e3o":[111],"\u03b2-lactamases,":[113],"modifica\u00e7\u00e3o":[114],"alvos":[116],"moleculares,":[117],"redu\u00e7\u00e3o":[118],"permeabilidade":[120],"membrana":[122],"externa,":[123],"superexpress\u00e3o":[124],"bombas":[126],"efluxo":[128],"altera\u00e7\u00f5es":[130],"lipopolissacar\u00eddeo.":[132],"Adicionalmente,":[133],"organiza\u00e7\u00e3o":[135],"confere":[138],"toler\u00e2ncia":[140],"aos":[141],"antimicrobianos":[142],"dificulta":[144],"a\u00e7\u00e3o":[146],"do":[147,150],"sistema":[148],"imune":[149],"hospedeiro,":[151],"favorecendo":[152],"cr\u00f4nicas":[154],"persistentes.":[156],"Nesse":[157],"contexto,":[158],"este":[159],"artigo":[160],"revisa":[161],"forma":[163],"cr\u00edtica":[164],"integrada":[166],"os":[167,173],"antimicrobiana,":[172],"aspectos":[174],"epidemiol\u00f3gicos":[175],"import\u00e2ncia":[178],"hospitalar":[179],"aeruginosa,":[182],"enfatizando":[183],"essas":[185],"caracter\u00edsticas":[186],"evidenciam":[187],"necessidade":[189],"urgente":[190],"desenvolvimento":[192],"novos":[194],"antibi\u00f3ticos":[195],"estrat\u00e9gias":[197],"inovadoras,":[199],"capazes":[200],"superar":[202],"existente":[205],"atuar":[207],"eficazmente":[208],"contra":[209],"bact\u00e9rias":[210],"organizadas":[213],"biofilmes.":[215]},"counts_by_year":[{"year":2026,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2026-02-03T00:00:00"}