{"id":"https://openalex.org/W7126209674","doi":"https://doi.org/10.21873/anticanres.17996","title":"Anatomical-specific Lymphatic Route Beyond Mesorectal Fascia: Analyses from Female Cadavers and Patients With Rectal Cancer","display_name":"Anatomical-specific Lymphatic Route Beyond Mesorectal Fascia: Analyses from Female Cadavers and Patients With Rectal Cancer","publication_year":2026,"publication_date":"2026-01-30","ids":{"openalex":"https://openalex.org/W7126209674","doi":"https://doi.org/10.21873/anticanres.17996","pmid":"https://pubmed.ncbi.nlm.nih.gov/41617432"},"language":"en","primary_location":{"id":"doi:10.21873/anticanres.17996","doi":"https://doi.org/10.21873/anticanres.17996","is_oa":true,"landing_page_url":"https://doi.org/10.21873/anticanres.17996","pdf_url":null,"source":{"id":"https://openalex.org/S157347057","display_name":"Anticancer Research","issn_l":"0250-7005","issn":["0250-7005","1791-7530"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4320800545","host_organization_name":"International Institute of Anticancer Research (IIAR) Conferences 1997. Athens, Greece. Abstracts","host_organization_lineage":["https://openalex.org/P4320800545"],"host_organization_lineage_names":["International Institute of Anticancer Research (IIAR) Conferences 1997. Athens, Greece. Abstracts"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Anticancer Research","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.21873/anticanres.17996","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5017395921","display_name":"Daisuke Kuwata","orcid":"https://orcid.org/0000-0003-3030-813X","observed_orcids":["https://orcid.org/0000-0003-3030-813X"]},"institutions":[{"id":"https://openalex.org/I146516829","display_name":"Hirosaki University","ror":"https://ror.org/02syg0q74","country_code":"JP","type":"education","lineage":["https://openalex.org/I146516829"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"DAISUKE KUWATA","raw_affiliation_strings":["Department of Anatomical Science, Hirosaki University, Graduate School of Medicine, Hirosaki, Japan","Department of Gastroenterological Surgery, Hirosaki University, Graduate School of Medicine, Hirosaki, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anatomical Science, Hirosaki University, Graduate School of Medicine, Hirosaki, Japan","institution_ids":["https://openalex.org/I146516829"]},{"raw_affiliation_string":"Department of Gastroenterological Surgery, Hirosaki University, Graduate School of Medicine, Hirosaki, Japan","institution_ids":["https://openalex.org/I146516829"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101997233","display_name":"Hiroshi Shimoda","orcid":"https://orcid.org/0000-0002-6871-3715","observed_orcids":["https://orcid.org/0000-0002-6871-3715"]},"institutions":[{"id":"https://openalex.org/I146516829","display_name":"Hirosaki University","ror":"https://ror.org/02syg0q74","country_code":"JP","type":"education","lineage":["https://openalex.org/I146516829"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"HIROSHI SHIMODA","raw_affiliation_strings":["Department of Anatomical Science, Hirosaki University, Graduate School of Medicine, Hirosaki, Japan","Department of Neuroanatomy, Cell Biology, Histology, Hirosaki University, Graduate School of Medicine, Hirosaki, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anatomical Science, Hirosaki University, Graduate School of Medicine, Hirosaki, Japan","institution_ids":["https://openalex.org/I146516829"]},{"raw_affiliation_string":"Department of Neuroanatomy, Cell Biology, Histology, Hirosaki University, Graduate School of Medicine, Hirosaki, Japan","institution_ids":["https://openalex.org/I146516829"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102066861","display_name":"Takuya Miura","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I146516829","display_name":"Hirosaki University","ror":"https://ror.org/02syg0q74","country_code":"JP","type":"education","lineage":["https://openalex.org/I146516829"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"TAKUYA MIURA","raw_affiliation_strings":["Department of Gastroenterological Surgery, Hirosaki University, Graduate School of Medicine, Hirosaki, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gastroenterological Surgery, Hirosaki University, Graduate School of Medicine, Hirosaki, Japan","institution_ids":["https://openalex.org/I146516829"]}]},{"author_position":"middle","author":{"id":null,"display_name":"TOMOHIRO CHIBA","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I146516829","display_name":"Hirosaki University","ror":"https://ror.org/02syg0q74","country_code":"JP","type":"education","lineage":["https://openalex.org/I146516829"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"TOMOHIRO CHIBA","raw_affiliation_strings":["Department of Anatomical Science, Hirosaki University, Graduate School of Medicine, Hirosaki, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anatomical Science, Hirosaki University, Graduate School of Medicine, Hirosaki, Japan","institution_ids":["https://openalex.org/I146516829"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032516662","display_name":"Kentaro Sato","orcid":"https://orcid.org/0000-0002-1765-7477","observed_orcids":["https://orcid.org/0000-0002-1765-7477"]},"institutions":[{"id":"https://openalex.org/I146516829","display_name":"Hirosaki University","ror":"https://ror.org/02syg0q74","country_code":"JP","type":"education","lineage":["https://openalex.org/I146516829"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"KENTARO SATO","raw_affiliation_strings":["Department of Gastroenterological Surgery, Hirosaki University, Graduate School of Medicine, Hirosaki, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gastroenterological Surgery, Hirosaki University, Graduate School of Medicine, Hirosaki, Japan","institution_ids":["https://openalex.org/I146516829"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048146387","display_name":"Yuki Shiroto","orcid":"https://orcid.org/0000-0003-0874-6846","observed_orcids":["https://orcid.org/0000-0003-0874-6846"]},"institutions":[{"id":"https://openalex.org/I146516829","display_name":"Hirosaki University","ror":"https://ror.org/02syg0q74","country_code":"JP","type":"education","lineage":["https://openalex.org/I146516829"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"YUKI SHIROTO","raw_affiliation_strings":["Department of Anatomical Science, Hirosaki University, Graduate School of Medicine, Hirosaki, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anatomical Science, Hirosaki University, Graduate School of Medicine, Hirosaki, Japan","institution_ids":["https://openalex.org/I146516829"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076910510","display_name":"Yoshiyuki Sakamoto","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I146516829","display_name":"Hirosaki University","ror":"https://ror.org/02syg0q74","country_code":"JP","type":"education","lineage":["https://openalex.org/I146516829"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"YOSHIYUKI SAKAMOTO","raw_affiliation_strings":["Department of Gastroenterological Surgery, Hirosaki University, Graduate School of Medicine, Hirosaki, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gastroenterological Surgery, Hirosaki University, Graduate School of Medicine, Hirosaki, Japan","institution_ids":["https://openalex.org/I146516829"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065509343","display_name":"Hajime Morohashi","orcid":"https://orcid.org/0000-0003-2040-753X","observed_orcids":["https://orcid.org/0000-0003-2040-753X"]},"institutions":[{"id":"https://openalex.org/I146516829","display_name":"Hirosaki University","ror":"https://ror.org/02syg0q74","country_code":"JP","type":"education","lineage":["https://openalex.org/I146516829"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"HAJIME MOROHASHI","raw_affiliation_strings":["Department of Gastroenterological Surgery, Hirosaki University, Graduate School of Medicine, Hirosaki, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gastroenterological Surgery, Hirosaki University, Graduate School of Medicine, Hirosaki, Japan","institution_ids":["https://openalex.org/I146516829"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000345028","display_name":"Takuji Kagiya","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I146516829","display_name":"Hirosaki University","ror":"https://ror.org/02syg0q74","country_code":"JP","type":"education","lineage":["https://openalex.org/I146516829"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"TAKUJI KAGIYA","raw_affiliation_strings":["Department of Gastroenterological Surgery, Hirosaki University, Graduate School of Medicine, Hirosaki, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gastroenterological Surgery, Hirosaki University, Graduate School of Medicine, Hirosaki, Japan","institution_ids":["https://openalex.org/I146516829"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5002019305","display_name":"Kenichi Hakamada","orcid":"https://orcid.org/0000-0001-6513-1202","observed_orcids":["https://orcid.org/0000-0001-6513-1202"]},"institutions":[{"id":"https://openalex.org/I146516829","display_name":"Hirosaki University","ror":"https://ror.org/02syg0q74","country_code":"JP","type":"education","lineage":["https://openalex.org/I146516829"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"KENICHI HAKAMADA","raw_affiliation_strings":["Department of Gastroenterological Surgery, Hirosaki University, Graduate School of Medicine, Hirosaki, Japan; hakamada@hirosaki-u.ac.jp"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gastroenterological Surgery, Hirosaki University, Graduate School of Medicine, Hirosaki, Japan; hakamada@hirosaki-u.ac.jp","institution_ids":["https://openalex.org/I146516829"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I146516829"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"46","issue":"2","first_page":"885","last_page":"899"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10335","display_name":"Colorectal Cancer Surgical Treatments","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10335","display_name":"Colorectal Cancer Surgical Treatments","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11469","display_name":"Lymphatic System and Diseases","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10696","display_name":"Gastric Cancer Management and Outcomes","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/lymphatic-network","display_name":"lymphatic network","score":0.6549999713897705},{"id":"https://openalex.org/keywords/low-rectal-cancer","display_name":"low rectal cancer","score":0.8299999833106995},{"id":"https://openalex.org/keywords/mesorectal-fascia","display_name":"mesorectal fascia","score":0.7409999966621399},{"id":"https://openalex.org/keywords/anorectum","display_name":"anorectum","score":0.6830000281333923},{"id":"https://openalex.org/keywords/dentate-line","display_name":"dentate line","score":0.6909999847412109},{"id":"https://openalex.org/keywords/levator-ani-muscle","display_name":"levator ani muscle","score":0.8399999737739563},{"id":"https://openalex.org/keywords/perivascular-spaces","display_name":"perivascular spaces","score":0.6190000176429749},{"id":"https://openalex.org/keywords/total-mesorectal-excision","display_name":"total mesorectal excision","score":0.843999981880188},{"id":"https://openalex.org/keywords/neoadjuvant-chemoradiotherapy","display_name":"neoadjuvant chemoradiotherapy","score":0.7400000095367432},{"id":"https://openalex.org/keywords/tumor-location","display_name":"tumor location","score":0.671999990940094},{"id":"https://openalex.org/keywords/disease-free-survival","display_name":"disease-free survival","score":0.7620000243186951},{"id":"https://openalex.org/keywords/tumor-recurrence","display_name":"tumor recurrence","score":0.5809999704360962},{"id":"https://openalex.org/keywords/female-cadaver","display_name":"female cadaver","score":0.5419999957084656}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8557999730110168},{"id":"https://openalex.org/C181152851","wikidata":"https://www.wikidata.org/wiki/Q712604","display_name":"Lymphatic system","level":2,"score":0.6693000197410583},{"id":"https://openalex.org/C526805850","wikidata":"https://www.wikidata.org/wiki/Q188874","display_name":"Colorectal cancer","level":3,"score":0.6398000121116638},{"id":"https://openalex.org/C2781074409","wikidata":"https://www.wikidata.org/wiki/Q158716","display_name":"Rectum","level":2,"score":0.5753999948501587},{"id":"https://openalex.org/C2777201421","wikidata":"https://www.wikidata.org/wiki/Q2445481","display_name":"Total mesorectal excision","level":4,"score":0.5393000245094299},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.448199987411499},{"id":"https://openalex.org/C2778740770","wikidata":"https://www.wikidata.org/wiki/Q6708283","display_name":"Lymphovascular invasion","level":4,"score":0.41370001435279846},{"id":"https://openalex.org/C91762617","wikidata":"https://www.wikidata.org/wiki/Q48422","display_name":"Cadaver","level":2,"score":0.4081999957561493},{"id":"https://openalex.org/C2775862295","wikidata":"https://www.wikidata.org/wiki/Q2660911","display_name":"Dissection (medical)","level":2,"score":0.3720000088214874},{"id":"https://openalex.org/C2910692049","wikidata":"https://www.wikidata.org/wiki/Q1135563","display_name":"Mesorectum","level":5,"score":0.3513000011444092},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.3434999883174896},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.3037000000476837},{"id":"https://openalex.org/C2781223772","wikidata":"https://www.wikidata.org/wiki/Q936531","display_name":"Fascia","level":2,"score":0.2976999878883362},{"id":"https://openalex.org/C2909851247","wikidata":"https://www.wikidata.org/wiki/Q1209892","display_name":"Rectal Polyp","level":3,"score":0.2976999878883362},{"id":"https://openalex.org/C2780365412","wikidata":"https://www.wikidata.org/wiki/Q2062483","display_name":"Rectal prolapse","level":3,"score":0.29589998722076416},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.29490000009536743},{"id":"https://openalex.org/C2780035688","wikidata":"https://www.wikidata.org/wiki/Q2465231","display_name":"Anal canal","level":3,"score":0.2705000042915344},{"id":"https://openalex.org/C61434518","wikidata":"https://www.wikidata.org/wiki/Q932510","display_name":"General surgery","level":1,"score":0.257099986076355},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.2563000023365021},{"id":"https://openalex.org/C2779455797","wikidata":"https://www.wikidata.org/wiki/Q233316","display_name":"Sacrum","level":2,"score":0.250900000333786}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002102","descriptor_name":"Cadaver","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005205","descriptor_name":"Fascia","qualifier_ui":"Q000033","qualifier_name":"anatomy & histology","is_major_topic":true},{"descriptor_ui":"D005205","descriptor_name":"Fascia","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012004","descriptor_name":"Rectal Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D012004","descriptor_name":"Rectal Neoplasms","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":true},{"descriptor_ui":"D012007","descriptor_name":"Rectum","qualifier_ui":"Q000033","qualifier_name":"anatomy & histology","is_major_topic":true},{"descriptor_ui":"D012007","descriptor_name":"Rectum","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D012007","descriptor_name":"Rectum","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":true},{"descriptor_ui":"D042601","descriptor_name":"Lymphatic Vessels","qualifier_ui":"Q000033","qualifier_name":"anatomy & histology","is_major_topic":true},{"descriptor_ui":"D042601","descriptor_name":"Lymphatic Vessels","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.21873/anticanres.17996","doi":"https://doi.org/10.21873/anticanres.17996","is_oa":true,"landing_page_url":"https://doi.org/10.21873/anticanres.17996","pdf_url":null,"source":{"id":"https://openalex.org/S157347057","display_name":"Anticancer Research","issn_l":"0250-7005","issn":["0250-7005","1791-7530"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4320800545","host_organization_name":"International Institute of Anticancer Research (IIAR) Conferences 1997. Athens, Greece. Abstracts","host_organization_lineage":["https://openalex.org/P4320800545"],"host_organization_lineage_names":["International Institute of Anticancer Research (IIAR) Conferences 1997. Athens, Greece. Abstracts"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Anticancer Research","raw_type":"journal-article"},{"id":"pmid:41617432","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/41617432","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Anticancer research","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.21873/anticanres.17996","doi":"https://doi.org/10.21873/anticanres.17996","is_oa":true,"landing_page_url":"https://doi.org/10.21873/anticanres.17996","pdf_url":null,"source":{"id":"https://openalex.org/S157347057","display_name":"Anticancer Research","issn_l":"0250-7005","issn":["0250-7005","1791-7530"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4320800545","host_organization_name":"International Institute of Anticancer Research (IIAR) Conferences 1997. Athens, Greece. Abstracts","host_organization_lineage":["https://openalex.org/P4320800545"],"host_organization_lineage_names":["International Institute of Anticancer Research (IIAR) Conferences 1997. Athens, Greece. Abstracts"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Anticancer Research","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.98580002784729,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W3127087792","https://openalex.org/W2363421197","https://openalex.org/W4317517606","https://openalex.org/W2088235491","https://openalex.org/W2313685520","https://openalex.org/W3204930742","https://openalex.org/W2057611540","https://openalex.org/W2801047448","https://openalex.org/W2354165289","https://openalex.org/W189420027"],"abstract_inverted_index":{"BACKGROUND/AIM:":[0],"This":[1],"study":[2],"aimed":[3],"to":[4,115,152,199,213],"clarify":[5],"the":[6,10,41,44,49,53,81,85,88,95,109,118,122,129,132,138,149,153,156,159,162,185,217],"lymphatic":[7],"network":[8,192,210],"around":[9,195],"anorectum":[11,196],"using":[12,37],"cadavers":[13,36],"and":[14,91,105,128,170,175,187],"consider":[15],"a":[16,180,200],"treatment":[17],"strategy":[18],"for":[19,172,220],"locally":[20],"advanced":[21],"lower":[22],"rectal":[23],"cancer":[24],"(LARC).":[25],"MATERIALS":[26],"AND":[27],"METHODS:":[28],"We":[29,51],"performed":[30],"microscopic":[31],"observations":[32],"of":[33,48,56,84,131,155,208],"three":[34],"female":[35],"India":[38],"ink":[39,123,145],"into":[40,94],"submucosa":[42],"at":[43],"dentate":[45],"line":[46],"(DL)":[47],"cadaver.":[50],"examined":[52],"clinical":[54],"outcomes":[55],"74":[57],"patients":[58],"with":[59,179],"LARC":[60],"who":[61],"underwent":[62],"total":[63],"mesorectal":[64],"excision":[65],"after":[66],"preoperative":[67],"treatment,":[68],"classifying":[69],"them":[70],"as":[71],"anterior":[72,186],"(A),":[73],"lateral":[74,119],"(L),":[75],"or":[76],"posterior":[77,120,139,188],"(P)":[78],"based":[79],"on":[80,137],"deepest":[82],"part":[83],"tumor.":[86],"RESULTS:":[87],"perivascular":[89],"space":[90],"was":[92,197,211],"absorbed":[93,144],"vaginal":[96],"lymph":[97,106,141],"vessels.":[98],"One":[99],"case":[100],"did":[101],"not":[102],"have":[103],"DVF,":[104],"vessels":[107,142],"in":[108,112,184,216],"rectum":[110],"distributed":[111],"close":[113],"proximity":[114],"vagina.":[116],"On":[117],"wall,":[121,140],"spread":[124,198],"extensively":[125],"from":[126,148],"DL":[127],"front":[130,154],"levator":[133],"ani":[134],"muscle,":[135],"whereas":[136],"containing":[143],"were":[146,167],"observed":[147],"hiatal":[150],"ligament":[151],"sacrum.":[157],"In":[158],"survival":[160,165],"analysis,":[161],"3-year":[163],"disease-free":[164],"rates":[166],"71.9%,":[168],"100%,":[169],"69.7%":[171],"A,":[173],"L,":[174],"P":[176],"groups,":[177],"respectively,":[178],"higher":[181],"recurrence":[182],"rate":[183],"walls.":[189],"CONCLUSION:":[190],"Lymphatic":[191],"beyond":[193],"fascia":[194],"specific":[201],"route":[202],"by":[203],"location.":[204],"The":[205],"anatomical":[206],"diversity":[207],"this":[209],"thought":[212],"be":[214],"involved":[215],"poor":[218],"outcome":[219],"LARC.":[221]},"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2026-02-01T00:00:00"}