{"id":"https://openalex.org/W7125715500","doi":"https://doi.org/10.1714/630.7355","title":"Come e quando impiegare la duplice antiaggregazione nel paziente in trattamento con anticoagulanti orali?","display_name":"Come e quando impiegare la duplice antiaggregazione nel paziente in trattamento con anticoagulanti orali?","publication_year":2008,"publication_date":"2008-11-01","ids":{"openalex":"https://openalex.org/W7125715500","doi":"https://doi.org/10.1714/630.7355","pmid":"https://pubmed.ncbi.nlm.nih.gov/19058665"},"language":"it","primary_location":{"id":"doi:10.1714/630.7355","doi":"https://doi.org/10.1714/630.7355","is_oa":true,"landing_page_url":"https://doi.org/10.1714/630.7355","pdf_url":"https://www.giornaledicardiologia.it/r.php?&v=630&a=7355&l=10263&f=allegati/00630_2008_11/fulltext/2008-11.03 745-752.pdf","source":{"id":"https://openalex.org/S4393917769","display_name":"Giornale italiano di cardiologia","issn_l":"0046-5968","issn":["0046-5968","1827-6806"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["anvur-scientific","medline","norway-1","poland-20","russia-white-list-3"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Giornale Italiano di Cardiologia","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://www.giornaledicardiologia.it/r.php?&v=630&a=7355&l=10263&f=allegati/00630_2008_11/fulltext/2008-11.03 745-752.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5060497936","display_name":"Andrea Rubboli","orcid":"https://orcid.org/0000-0001-8657-6235","observed_orcids":["https://orcid.org/0000-0001-8657-6235"]},"institutions":[{"id":"https://openalex.org/I4210098325","display_name":"Ospedale Maggiore Carlo Alberto Pizzardi","ror":"https://ror.org/010tmdc88","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210098325","https://openalex.org/I4210119117","https://openalex.org/I4210153126"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Andrea Rubboli","raw_affiliation_strings":["Laboratorio di Emodinamica U.O. di Cardiologia Ospedale Maggiore Largo Nigrisoli , 2 40133 Bologna","U.O. di Cardiologia , Ospedale Maggiore , Bologna"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratorio di Emodinamica U.O. di Cardiologia Ospedale Maggiore Largo Nigrisoli , 2 40133 Bologna","institution_ids":[]},{"raw_affiliation_string":"U.O. di Cardiologia , Ospedale Maggiore , Bologna","institution_ids":["https://openalex.org/I4210098325"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5107868633","display_name":"Giuseppe Di Pasquale","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Giuseppe Di Pasquale","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"9","issue":"11","first_page":"745","last_page":"52"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11064","display_name":"Antiplatelet Therapy and Cardiovascular Diseases","score":0.9775000214576721,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11064","display_name":"Antiplatelet Therapy and Cardiovascular Diseases","score":0.9775000214576721,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10193","display_name":"Coronary Interventions and Diagnostics","score":0.022299999371170998,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10292","display_name":"Acute Myocardial Infarction Research","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dual-antiplatelet-therapy","display_name":"dual antiplatelet therapy","score":0.8820000290870667},{"id":"https://openalex.org/keywords/oral-anticoagulation","display_name":"oral anticoagulation","score":0.8899999856948853},{"id":"https://openalex.org/keywords/coronary-stenting","display_name":"coronary stenting","score":0.8930000066757202},{"id":"https://openalex.org/keywords/triple-therapy","display_name":"triple therapy","score":0.8629999756813049},{"id":"https://openalex.org/keywords/aspirin","display_name":"aspirin","score":0.8759999871253967},{"id":"https://openalex.org/keywords/clopidogrel","display_name":"clopidogrel","score":1.0},{"id":"https://openalex.org/keywords/stent-thrombosis","display_name":"stent thrombosis","score":0.8769999742507935},{"id":"https://openalex.org/keywords/drug-eluting-stents","display_name":"drug-eluting stents","score":0.7749999761581421},{"id":"https://openalex.org/keywords/bare-metal-stents","display_name":"bare-metal stents","score":1.0},{"id":"https://openalex.org/keywords/bleeding-risk","display_name":"bleeding risk","score":0.7829999923706055},{"id":"https://openalex.org/keywords/antithrombotic-therapy","display_name":"antithrombotic therapy","score":0.6330000162124634}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8973000049591064},{"id":"https://openalex.org/C15708023","wikidata":"https://www.wikidata.org/wiki/Q80083","display_name":"Humanities","level":1,"score":0.6384999752044678},{"id":"https://openalex.org/C2778583881","wikidata":"https://www.wikidata.org/wiki/Q1325542","display_name":"Stent","level":2,"score":0.41110000014305115},{"id":"https://openalex.org/C29456083","wikidata":"https://www.wikidata.org/wiki/Q1221899","display_name":"Gynecology","level":1,"score":0.3944000005722046},{"id":"https://openalex.org/C2989005","wikidata":"https://www.wikidata.org/wiki/Q214963","display_name":"Nuclear medicine","level":1,"score":0.27160000801086426},{"id":"https://openalex.org/C2777849778","wikidata":"https://www.wikidata.org/wiki/Q410237","display_name":"Clopidogrel","level":3,"score":0.24979999661445618},{"id":"https://openalex.org/C2777628954","wikidata":"https://www.wikidata.org/wiki/Q18216","display_name":"Aspirin","level":2,"score":0.20010000467300415},{"id":"https://openalex.org/C3019004856","wikidata":"https://www.wikidata.org/wiki/Q42297149","display_name":"Coronary angiography","level":3,"score":0.17749999463558197},{"id":"https://openalex.org/C3018386432","wikidata":"https://www.wikidata.org/wiki/Q426449","display_name":"Endovascular treatment","level":3,"score":0.17430000007152557},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.1607999950647354}],"mesh":[{"descriptor_ui":"D000284","descriptor_name":"Administration, Oral","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000925","descriptor_name":"Anticoagulants","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D003331","descriptor_name":"Coronary Vessels","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":true},{"descriptor_ui":"D004359","descriptor_name":"Drug Therapy, Combination","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010975","descriptor_name":"Platelet Aggregation Inhibitors","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D013923","descriptor_name":"Thromboembolism","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D013923","descriptor_name":"Thromboembolism","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":false},{"descriptor_ui":"D013927","descriptor_name":"Thrombosis","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D013927","descriptor_name":"Thrombosis","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true},{"descriptor_ui":"D015607","descriptor_name":"Stents","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1714/630.7355","doi":"https://doi.org/10.1714/630.7355","is_oa":true,"landing_page_url":"https://doi.org/10.1714/630.7355","pdf_url":"https://www.giornaledicardiologia.it/r.php?&v=630&a=7355&l=10263&f=allegati/00630_2008_11/fulltext/2008-11.03 745-752.pdf","source":{"id":"https://openalex.org/S4393917769","display_name":"Giornale italiano di cardiologia","issn_l":"0046-5968","issn":["0046-5968","1827-6806"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["anvur-scientific","medline","norway-1","poland-20","russia-white-list-3"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Giornale Italiano di Cardiologia","raw_type":"journal-article"},{"id":"pmid:19058665","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19058665","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Giornale italiano di cardiologia (2006)","raw_type":"English Abstract"}],"best_oa_location":{"id":"doi:10.1714/630.7355","doi":"https://doi.org/10.1714/630.7355","is_oa":true,"landing_page_url":"https://doi.org/10.1714/630.7355","pdf_url":"https://www.giornaledicardiologia.it/r.php?&v=630&a=7355&l=10263&f=allegati/00630_2008_11/fulltext/2008-11.03 745-752.pdf","source":{"id":"https://openalex.org/S4393917769","display_name":"Giornale italiano di cardiologia","issn_l":"0046-5968","issn":["0046-5968","1827-6806"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["anvur-scientific","medline","norway-1","poland-20","russia-white-list-3"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Giornale Italiano di Cardiologia","raw_type":"journal-article"},"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7125715500.pdf","grobid_xml":"https://content.openalex.org/works/W7125715500.grobid-xml"},"referenced_works_count":35,"referenced_works":["https://openalex.org/W138786927","https://openalex.org/W1475865131","https://openalex.org/W1553345686","https://openalex.org/W1968820256","https://openalex.org/W1969089883","https://openalex.org/W1978876468","https://openalex.org/W1982104017","https://openalex.org/W1994703729","https://openalex.org/W2011007155","https://openalex.org/W2023134244","https://openalex.org/W2029536227","https://openalex.org/W2041726140","https://openalex.org/W2047740656","https://openalex.org/W2051557900","https://openalex.org/W2055629371","https://openalex.org/W2057754028","https://openalex.org/W2066879234","https://openalex.org/W2073437025","https://openalex.org/W2075868476","https://openalex.org/W2082378560","https://openalex.org/W2087236942","https://openalex.org/W2094667843","https://openalex.org/W2099409915","https://openalex.org/W2105005467","https://openalex.org/W2119746736","https://openalex.org/W2122473579","https://openalex.org/W2127489984","https://openalex.org/W2148363010","https://openalex.org/W2156613835","https://openalex.org/W2162245427","https://openalex.org/W2171290820","https://openalex.org/W2256930820","https://openalex.org/W2611749980","https://openalex.org/W2616526627","https://openalex.org/W2744079636"],"related_works":["https://openalex.org/W7033612896","https://openalex.org/W168770737","https://openalex.org/W2046900083","https://openalex.org/W7125674838","https://openalex.org/W2319821137","https://openalex.org/W1594670927","https://openalex.org/W2080837516","https://openalex.org/W2160333145","https://openalex.org/W2413969765","https://openalex.org/W1510783602"],"abstract_inverted_index":{"The":[0,142,193],"optimal":[1,216],"antithrombotic":[2,191,217],"treatment":[3,48,218],"for":[4,29,60,87],"patients":[5,34],"on":[6],"oral":[7],"anticoagulation":[8],"(OAC)":[9],"undergoing":[10],"coronary":[11],"artery":[12],"stenting":[13],"is":[14,24,44,63,140,151],"currently":[15,21],"undefined.":[16],"In":[17,124],"this":[18,125,220],"review,":[19],"the":[20,30,45,57,88,94,104,106,118,127,145,162,165,171,215],"available":[22],"evidence":[23],"examined,":[25],"and":[26,42,53,85,114,149,167,175,200],"practical":[27],"recommendations":[28,195],"management":[31],"of":[32,66,108,120,129,137,144,147,170,173,189],"these":[33],"are":[35,196,211],"given.":[36],"Triple":[37],"therapy":[38,139],"with":[39,69,133],"aspirin,":[40],"clopidogrel":[41,174],"OAC":[43,62,150],"most":[46],"effective":[47],"to":[49,56,79,93,187,213],"prevent":[50],"stent":[51],"thrombosis":[52],"thromboembolism":[54],"related":[55],"clinical":[58],"conditions":[59,80],"which":[61,203],"indicated.":[64],"Because":[65],"its":[67],"association":[68],"a":[70],"relevant":[71],"hemorrhagic":[72,122],"risk,":[73],"however,":[74],"it":[75],"should":[76,100,111],"be":[77,101,112,159],"reserved":[78],"at":[81,180],"high":[82,121],"thromboembolic":[83],"risk":[84],"administered":[86],"shortest":[89],"possible":[90],"time.":[91],"Owing":[92],"more":[95],"rapid":[96],"re-endothelization,":[97],"bare-metal":[98,130],"stents":[99,110,131],"preferred.":[102],"On":[103,161],"contrary,":[105],"use":[107],"drug-eluting":[109],"limited,":[113],"absolutely":[115],"avoided":[116],"in":[117,219],"presence":[119],"risk.":[123],"case,":[126],"implantation":[128],"associated":[132],"only":[134],"2":[135],"weeks":[136],"triple":[138],"recommended.":[141],"efficacy":[143,168],"combination":[146,172],"aspirin":[148],"suboptimal,":[152],"so":[153],"that":[154,188],"such":[155],"regimen":[156],"must":[157],"not":[158,178],"used.":[160],"other":[163,190],"hand,":[164],"safety":[166],"profiles":[169],"OAC,":[176],"although":[177],"supported":[179],"present":[181],"by":[182],"solid":[183],"data,":[184],"appears":[185],"similar":[186],"combinations.":[192],"above":[194],"derived":[197],"from":[198],"small":[199],"uncontrolled":[201],"populations,":[202],"were":[204],"retrospectively":[205],"examined.":[206],"Therefore,":[207],"large-scale":[208],"prospective":[209],"studies":[210],"needed":[212],"determine":[214],"patient":[221],"population.":[222]},"counts_by_year":[],"updated_date":"2026-11-08T12:12:28.789561","created_date":"2026-01-27T00:00:00"}