{"id":"https://openalex.org/W7125611366","doi":"https://doi.org/10.29327/1716874.42-701","title":"THE EFFECT OF CORTICOSTEROIDS ON THE RISK OF SERIOUS ADVERSE EVENTS IN RHEUMATOID ARTHRITIS: SIMULATING A RANDOMIZED CONTROLLED TRIAL","display_name":"THE EFFECT OF CORTICOSTEROIDS ON THE RISK OF SERIOUS ADVERSE EVENTS IN RHEUMATOID ARTHRITIS: SIMULATING A RANDOMIZED CONTROLLED TRIAL","publication_year":2025,"publication_date":"2025-01-01","ids":{"openalex":"https://openalex.org/W7125611366","doi":"https://doi.org/10.29327/1716874.42-701"},"language":"en","primary_location":{"id":"doi:10.29327/1716874.42-701","doi":"https://doi.org/10.29327/1716874.42-701","is_oa":false,"landing_page_url":"https://doi.org/10.29327/1716874.42-701","pdf_url":null,"source":{"id":"https://openalex.org/S4306501749","display_name":"Congresso Brasileiro de Reumatologia","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"conference"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"XLII Congresso Brasileiro de Reumatologia","raw_type":"proceedings-article"},"volume":null,"type":"conference-paper","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5044492943","display_name":"Markus Bredemeier","orcid":"https://orcid.org/0000-0002-7911-593X","observed_orcids":["https://orcid.org/0000-0002-7911-593X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Markus Bredemeier","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007306772","display_name":"Alice de Moraes Baier","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Alice de Moraes Baier","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028523332","display_name":"Carolina Vieira Tavares","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Carolina Vieira Tavares","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5115702152","display_name":"Everson Reginatto","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Everson Reginatto","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5115703312","display_name":"Marina Silvestri Pauwelz","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Marina Silvestri Pauwelz","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049108731","display_name":"\u00c2ngela Luzia Branco Pinto Duarte","orcid":"https://orcid.org/0000-0001-6434-9939","observed_orcids":["https://orcid.org/0000-0001-6434-9939"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"\u00c2NGELA LUZIA BRANCO P DUARTE","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5123746931","display_name":"MARCELO DE MEIDEIROS PINHEIRO","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"MARCELO DE MEIDEIROS PINHEIRO","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011571058","display_name":"B\u00e1rbara Stadler Kahlow","orcid":"https://orcid.org/0000-0001-5292-2777","observed_orcids":["https://orcid.org/0000-0001-5292-2777"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"BARBARA STADLER KAHLOW","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021311091","display_name":"M.V.S.S. Vechi","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"MONICA VALERIA S SANTANA DE VECCHI","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5123762710","display_name":"MARINA ALVARENGA REZENDE BUSTAMANTE","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Marina Alvarenga Rezende Bustamante","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024201795","display_name":"J. Miranda","orcid":"https://orcid.org/0000-0002-2701-3720","observed_orcids":["https://orcid.org/0000-0002-2701-3720"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"JOS\u00c9 ROBERTO SILVA MIRANDA","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081453464","display_name":"Val\u00e9ria Valim Cristo","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"VAL\u00c9RIA VALIM CRISTO","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5123736673","display_name":"GLAUCIO RICARDO WEBNER DE CASTRO","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"GLAUCIO RICARDO WEBNER DE CASTRO","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5123783941","display_name":"Manoel Barros Bertolo","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"MANOEL BARROS B\u00c9RTOLO","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5123746374","display_name":"MARIA DE F\u00c1TIMA LOBATO DA C. SAUMA","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"MARIA DE F\u00c1TIMA LOBATO DA C. SAUMA","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076309045","display_name":"Vander Fernandes","orcid":"https://orcid.org/0000-0003-0505-473X","observed_orcids":["https://orcid.org/0000-0003-0505-473X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"VANDER FERNANDES","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075963523","display_name":"Ana Cristina de Medeiros Ribeiro","orcid":"https://orcid.org/0000-0001-7168-5906","observed_orcids":["https://orcid.org/0000-0001-7168-5906"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"ANA CRISTINA DE MEDEIROS RIBEIRO","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020418998","display_name":"Reginaldo Botelho","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"REGINALDO BOTELHO","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032935573","display_name":"Claiton Viegas Brenol","orcid":"https://orcid.org/0000-0003-0229-7912","observed_orcids":["https://orcid.org/0000-0003-0229-7912"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"CLAITON VIEGAS BRENOL","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039182882","display_name":"Regina Alice Fontes Von Kirchenheim","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Regina Alice Fontes Von Kirchenheim","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5123756136","display_name":"SAMIA ARAUJO DE SOUZA STUDART","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"SAMIA ARAUJO DE SOUZA STUDART","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008051751","display_name":"Geraldo da Rocha Castelar Pinheiro","orcid":"https://orcid.org/0000-0002-7778-569X","observed_orcids":["https://orcid.org/0000-0002-7778-569X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"GERALDO DA ROCHA CASTELAR PINHEIRO","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5123759357","display_name":"Laurindo Ferreira da Rocha Junior","orcid":"https://orcid.org/0000-0002-7090-561X","observed_orcids":["https://orcid.org/0000-0002-7090-561X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"LAURINDO . FERREIRA DA ROCHA JR","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113987572","display_name":"Hugo Deleon de Lima","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Hugo de Leon de Lima","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108249570","display_name":"Iv\u00e2nio Alves Pereira","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"IV\u00c2NIO ALVES PEREIRA","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007327127","display_name":"Morgana Ohira Gazzeta","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Morgana Ohira Gazzeta","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059287765","display_name":"Adriana Mar\u00eda Kakehasi","orcid":"https://orcid.org/0000-0001-9411-7493","observed_orcids":["https://orcid.org/0000-0001-9411-7493","https://orcid.org/0000-0003-4475-6064"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"ADRIANA MARIA KAKEHASI","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5123752255","display_name":"PAULO LOUZADA J\u00daNIOR","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"PAULO LOUZADA J\u00daNIOR","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058946570","display_name":"CRISTIANO LUPO","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Cristiano Lupo","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5123754694","display_name":"In\u00eas Guimar\u00e3es da Silveira","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"IN\u00caS GUIMAR\u00c3ES DA SILVEIRA","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5123757303","display_name":"SERGIO CANDIDO KOWALSKI KOWALSKI","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"SERGIO CANDIDO KOWALSKI KOWALSKI","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112674632","display_name":"David Cesar Titton","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"David Titton","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000574655","display_name":"Aline Ranzolin","orcid":"https://orcid.org/0000-0002-8260-2288","observed_orcids":["https://orcid.org/0000-0002-8260-2288"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Aline Ranzolin","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108614878","display_name":"R. S\u00e3o Francisco Xavier","orcid":"https://orcid.org/0000-0001-6570-4533","observed_orcids":["https://orcid.org/0000-0001-6570-4533"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ricardo Machado Xavier","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110263891","display_name":"I\u00eada Maria Magalh\u00e3es Laurindo","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ieda M M Laurindo","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5064141182","display_name":"Jos\u00e9 Eduardo Martinez","orcid":"https://orcid.org/0000-0002-3864-6822","observed_orcids":["https://orcid.org/0000-0002-3864-6822"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jos\u00e9 Eduardo Martinez","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.80813439,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10200","display_name":"Rheumatoid Arthritis Research and Therapies","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10200","display_name":"Rheumatoid Arthritis Research and Therapies","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11943","display_name":"Pharmacovigilance and Adverse Drug Reactions","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/3005","display_name":"Toxicology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10678","display_name":"Inflammatory mediators and NSAID effects","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/corticosteroids","display_name":"corticosteroids","score":0.9900000095367432},{"id":"https://openalex.org/keywords/rheumatoid-arthritis","display_name":"rheumatoid arthritis","score":0.9810000061988831},{"id":"https://openalex.org/keywords/serious-adverse-events","display_name":"serious adverse events","score":0.9580000042915344},{"id":"https://openalex.org/keywords/adverse-event-risk","display_name":"adverse event risk","score":0.5630000233650208},{"id":"https://openalex.org/keywords/glucocorticoid-therapy","display_name":"glucocorticoid therapy","score":0.7580000162124634}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8550999760627747},{"id":"https://openalex.org/C168563851","wikidata":"https://www.wikidata.org/wiki/Q1436668","display_name":"Randomized controlled trial","level":2,"score":0.7013999819755554},{"id":"https://openalex.org/C197934379","wikidata":"https://www.wikidata.org/wiki/Q2047938","display_name":"Adverse effect","level":2,"score":0.6909000277519226},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.39259999990463257},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.29910001158714294},{"id":"https://openalex.org/C535046627","wikidata":"https://www.wikidata.org/wiki/Q30612","display_name":"Clinical trial","level":2,"score":0.27630001306533813},{"id":"https://openalex.org/C12174686","wikidata":"https://www.wikidata.org/wiki/Q1058438","display_name":"Risk assessment","level":2,"score":0.2653000056743622},{"id":"https://openalex.org/C2777575956","wikidata":"https://www.wikidata.org/wiki/Q187255","display_name":"Rheumatoid arthritis","level":2,"score":0.25999999046325684},{"id":"https://openalex.org/C120195587","wikidata":"https://www.wikidata.org/wiki/Q2138790","display_name":"Absolute risk reduction","level":3,"score":0.25679999589920044},{"id":"https://openalex.org/C2779473830","wikidata":"https://www.wikidata.org/wiki/Q1540899","display_name":"MEDLINE","level":2,"score":0.25600001215934753}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.29327/1716874.42-701","doi":"https://doi.org/10.29327/1716874.42-701","is_oa":false,"landing_page_url":"https://doi.org/10.29327/1716874.42-701","pdf_url":null,"source":{"id":"https://openalex.org/S4306501749","display_name":"Congresso Brasileiro de Reumatologia","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"conference"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"XLII Congresso Brasileiro de Reumatologia","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9476000070571899,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4411401267","https://openalex.org/W1977359180","https://openalex.org/W2145917871","https://openalex.org/W2424360794","https://openalex.org/W2758585992","https://openalex.org/W1982459084","https://openalex.org/W7046613170","https://openalex.org/W2041610182","https://openalex.org/W2506953779","https://openalex.org/W7000408764"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2026-01-25T00:00:00"}