{"id":"https://openalex.org/W7125578092","doi":"https://doi.org/10.37933/nipes/7.4.2025.si198","title":"A Comprehensive Mathematical Modeling Approach to Assessing Typhoid Fever Transmission Dynamics","display_name":"A Comprehensive Mathematical Modeling Approach to Assessing Typhoid Fever Transmission Dynamics","publication_year":2025,"publication_date":"2025-11-06","ids":{"openalex":"https://openalex.org/W7125578092","doi":"https://doi.org/10.37933/nipes/7.4.2025.si198"},"language":"en","primary_location":{"id":"doi:10.37933/nipes/7.4.2025.si198","doi":"https://doi.org/10.37933/nipes/7.4.2025.si198","is_oa":true,"landing_page_url":"https://doi.org/10.37933/nipes/7.4.2025.si198","pdf_url":"https://journals.nipes.org/index.php/jstrissue/article/download/2330/1456","source":{"id":"https://openalex.org/S4210232884","display_name":"NIPES Journal of Science and Technology Research","issn_l":"2682-5821","issn":["2682-5821","2734-2352"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"NIPES Journal of Science and Technology Research","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://journals.nipes.org/index.php/jstrissue/article/download/2330/1456","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5081952466","display_name":"Florence Dami Ayegbusi","orcid":"https://orcid.org/0000-0002-2804-2494","observed_orcids":["https://orcid.org/0000-0002-2804-2494"]},"institutions":[{"id":"https://openalex.org/I4210161785","display_name":"Abiola Ajimobi Technical University Ibadan","ror":"https://ror.org/05tb13r23","country_code":"NG","type":"education","lineage":["https://openalex.org/I4210161785"]}],"countries":["NG"],"is_corresponding":false,"raw_author_name":"F. D. Ayegbusi","raw_affiliation_strings":["Mathematics & Statistics, Mathematics & Statistics Mathematics & Statistics Abiola Ajimobi Technical University Abiola Ajimobi Technical University Abiola Ajimobi Technical University Ibadan , Nigeria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Mathematics & Statistics, Mathematics & Statistics Mathematics & Statistics Abiola Ajimobi Technical University Abiola Ajimobi Technical University Abiola Ajimobi Technical University Ibadan , Nigeria","institution_ids":["https://openalex.org/I4210161785"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5123757678","display_name":"L.A Abimbola","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210161785","display_name":"Abiola Ajimobi Technical University Ibadan","ror":"https://ror.org/05tb13r23","country_code":"NG","type":"education","lineage":["https://openalex.org/I4210161785"]}],"countries":["NG"],"is_corresponding":false,"raw_author_name":"L.A Abimbola","raw_affiliation_strings":["Ibadan , Nigeria","Mathematics & Statistics, Mathematics & Statistics Mathematics & Statistics Abiola Ajimobi Technical University Abiola Ajimobi Technical University Abiola Ajimobi Technical University Ibadan , Nigeria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Ibadan , Nigeria","institution_ids":[]},{"raw_affiliation_string":"Mathematics & Statistics, Mathematics & Statistics Mathematics & Statistics Abiola Ajimobi Technical University Abiola Ajimobi Technical University Abiola Ajimobi Technical University Ibadan , Nigeria","institution_ids":["https://openalex.org/I4210161785"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5123757027","display_name":"A.B. Familua","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210161785","display_name":"Abiola Ajimobi Technical University Ibadan","ror":"https://ror.org/05tb13r23","country_code":"NG","type":"education","lineage":["https://openalex.org/I4210161785"]}],"countries":["NG"],"is_corresponding":false,"raw_author_name":"A.B. Familua","raw_affiliation_strings":["Ibadan , Nigeria","Mathematics & Statistics, Mathematics & Statistics Mathematics & Statistics Abiola Ajimobi Technical University Abiola Ajimobi Technical University Abiola Ajimobi Technical University Ibadan , Nigeria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Ibadan , Nigeria","institution_ids":[]},{"raw_affiliation_string":"Mathematics & Statistics, Mathematics & Statistics Mathematics & Statistics Abiola Ajimobi Technical University Abiola Ajimobi Technical University Abiola Ajimobi Technical University Ibadan , Nigeria","institution_ids":["https://openalex.org/I4210161785"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5123778799","display_name":"E. O. Ogunyemi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210161785","display_name":"Abiola Ajimobi Technical University Ibadan","ror":"https://ror.org/05tb13r23","country_code":"NG","type":"education","lineage":["https://openalex.org/I4210161785"]}],"countries":["NG"],"is_corresponding":false,"raw_author_name":"E. O. Ogunyemi","raw_affiliation_strings":["Mathematics & Statistics Abiola Ajimobi Technical University , Ibadan , Nigeria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Mathematics & Statistics Abiola Ajimobi Technical University , Ibadan , Nigeria","institution_ids":["https://openalex.org/I4210161785"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I4210161785"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.45567183,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"7","issue":"1","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10482","display_name":"Mathematical and Theoretical Epidemiology and Ecology Models","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2604","display_name":"Applied Mathematics"},"field":{"id":"https://openalex.org/fields/26","display_name":"Mathematics"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10482","display_name":"Mathematical and Theoretical Epidemiology and Ecology Models","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2604","display_name":"Applied Mathematics"},"field":{"id":"https://openalex.org/fields/26","display_name":"Mathematics"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10410","display_name":"COVID-19 epidemiological studies","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2611","display_name":"Modeling and Simulation"},"field":{"id":"https://openalex.org/fields/26","display_name":"Mathematics"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11560","display_name":"Animal Disease Management and Epidemiology","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1103","display_name":"Animal Science and Zoology"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/typhoid-fever","display_name":"typhoid fever","score":1.0},{"id":"https://openalex.org/keywords/transmission-dynamics","display_name":"transmission dynamics","score":0.7509999871253967},{"id":"https://openalex.org/keywords/vector-borne-diseases","display_name":"vector-borne diseases","score":0.8190000057220459},{"id":"https://openalex.org/keywords/insect-vectors","display_name":"insect vectors","score":0.4749999940395355},{"id":"https://openalex.org/keywords/compartmental-model","display_name":"compartmental model","score":0.703000009059906},{"id":"https://openalex.org/keywords/basic-reproduction-number","display_name":"basic reproduction number","score":0.9639999866485596},{"id":"https://openalex.org/keywords/disease-free-equilibrium","display_name":"disease-free equilibrium","score":0.9599999785423279},{"id":"https://openalex.org/keywords/endemic-equilibrium","display_name":"endemic equilibrium","score":0.9860000014305115},{"id":"https://openalex.org/keywords/global-stability","display_name":"global stability","score":0.9160000085830688},{"id":"https://openalex.org/keywords/sensitivity-analysis","display_name":"sensitivity analysis","score":0.7080000042915344},{"id":"https://openalex.org/keywords/vaccination","display_name":"vaccination","score":0.8629999756813049},{"id":"https://openalex.org/keywords/sanitation","display_name":"sanitation","score":0.9100000262260437},{"id":"https://openalex.org/keywords/insect-control","display_name":"insect control","score":0.6869999766349792},{"id":"https://openalex.org/keywords/public-health-interventions","display_name":"public health interventions","score":0.7139999866485596}],"concepts":[{"id":"https://openalex.org/C520601542","wikidata":"https://www.wikidata.org/wiki/Q83319","display_name":"Typhoid fever","level":2,"score":0.8104000091552734},{"id":"https://openalex.org/C204264503","wikidata":"https://www.wikidata.org/wiki/Q901464","display_name":"Basic reproduction number","level":3,"score":0.6189000010490417},{"id":"https://openalex.org/C761482","wikidata":"https://www.wikidata.org/wiki/Q118093","display_name":"Transmission (telecommunications)","level":2,"score":0.6144000291824341},{"id":"https://openalex.org/C2992243407","wikidata":"https://www.wikidata.org/wiki/Q525512","display_name":"Disease transmission","level":2,"score":0.5105000138282776},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.4925999939441681},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.47769999504089355},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.4350000023841858},{"id":"https://openalex.org/C112972136","wikidata":"https://www.wikidata.org/wiki/Q7595718","display_name":"Stability (learning theory)","level":2,"score":0.42969998717308044},{"id":"https://openalex.org/C138816342","wikidata":"https://www.wikidata.org/wiki/Q189603","display_name":"Public health","level":2,"score":0.3905999958515167},{"id":"https://openalex.org/C2909656726","wikidata":"https://www.wikidata.org/wiki/Q1347969","display_name":"Disease Eradication","level":3,"score":0.3763999938964844},{"id":"https://openalex.org/C112930515","wikidata":"https://www.wikidata.org/wiki/Q4389547","display_name":"Risk analysis (engineering)","level":1,"score":0.37130001187324524},{"id":"https://openalex.org/C2987315675","wikidata":"https://www.wikidata.org/wiki/Q1773974","display_name":"Disease control","level":2,"score":0.3643999993801117},{"id":"https://openalex.org/C2776714567","wikidata":"https://www.wikidata.org/wiki/Q7861081","display_name":"Typhoid vaccine","level":3,"score":0.3452000021934509},{"id":"https://openalex.org/C149782125","wikidata":"https://www.wikidata.org/wiki/Q160039","display_name":"Econometrics","level":1,"score":0.34040001034736633},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3190999925136566},{"id":"https://openalex.org/C77405623","wikidata":"https://www.wikidata.org/wiki/Q598451","display_name":"System dynamics","level":2,"score":0.3158000111579895},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.31380000710487366},{"id":"https://openalex.org/C76969082","wikidata":"https://www.wikidata.org/wiki/Q486902","display_name":"Mathematical model","level":2,"score":0.3098999857902527},{"id":"https://openalex.org/C2775924081","wikidata":"https://www.wikidata.org/wiki/Q55608371","display_name":"Control (management)","level":2,"score":0.2653000056743622},{"id":"https://openalex.org/C26517878","wikidata":"https://www.wikidata.org/wiki/Q228039","display_name":"Key (lock)","level":2,"score":0.26440000534057617},{"id":"https://openalex.org/C52103748","wikidata":"https://www.wikidata.org/wiki/Q2624927","display_name":"Susceptible individual","level":3,"score":0.2624000012874603},{"id":"https://openalex.org/C112758219","wikidata":"https://www.wikidata.org/wiki/Q16038819","display_name":"Duration (music)","level":2,"score":0.2547999918460846}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.37933/nipes/7.4.2025.si198","doi":"https://doi.org/10.37933/nipes/7.4.2025.si198","is_oa":true,"landing_page_url":"https://doi.org/10.37933/nipes/7.4.2025.si198","pdf_url":"https://journals.nipes.org/index.php/jstrissue/article/download/2330/1456","source":{"id":"https://openalex.org/S4210232884","display_name":"NIPES Journal of Science and Technology Research","issn_l":"2682-5821","issn":["2682-5821","2734-2352"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"NIPES Journal of Science and Technology Research","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.37933/nipes/7.4.2025.si198","doi":"https://doi.org/10.37933/nipes/7.4.2025.si198","is_oa":true,"landing_page_url":"https://doi.org/10.37933/nipes/7.4.2025.si198","pdf_url":"https://journals.nipes.org/index.php/jstrissue/article/download/2330/1456","source":{"id":"https://openalex.org/S4210232884","display_name":"NIPES Journal of Science and Technology Research","issn_l":"2682-5821","issn":["2682-5821","2734-2352"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"NIPES Journal of Science and Technology Research","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9391000270843506,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7125578092.pdf","grobid_xml":"https://content.openalex.org/works/W7125578092.grobid-xml"},"referenced_works_count":6,"referenced_works":["https://openalex.org/W4285797209","https://openalex.org/W4362585192","https://openalex.org/W4375932871","https://openalex.org/W4386776871","https://openalex.org/W4392193855","https://openalex.org/W4410028010"],"related_works":["https://openalex.org/W7134927025","https://openalex.org/W7162318925","https://openalex.org/W4394824080","https://openalex.org/W7133653860","https://openalex.org/W4401388000","https://openalex.org/W4416455953","https://openalex.org/W4410280977","https://openalex.org/W7203637996","https://openalex.org/W4404005773","https://openalex.org/W4386256040"],"abstract_inverted_index":{"This":[0,159],"paper":[1],"presents":[2],"a":[3,162],"mathematical":[4],"model":[5,27,160],"for":[6,152,165],"the":[7,29,56,64,72,83,86,96,111,154],"transmission":[8,42,168],"dynamics":[9],"of":[10,58,85,156],"typhoid":[11,157,167],"fever,":[12],"incorporating":[13],"both":[14],"human":[15],"and":[16,23,37,47,60,63,130,146,169],"insect":[17,147],"populations":[18],"to":[19,54,81,103,114],"analyze":[20],"disease":[21,41,104,136],"progression":[22],"control":[24,148],"strategies.":[25],"The":[26,138],"divides":[28],"population":[30],"into":[31],"susceptible,":[32],"exposed,":[33],"infected,":[34],"carrier,":[35],"vaccinated,":[36],"recovered":[38],"compartments,":[39],"exploring":[40],"across":[43],"human-to":[44],"human,":[45],"insect-to-human,":[46],"insect-to-insect":[48],"pathways.":[49],"Stability":[50],"analysis":[51,122],"is":[52,69,99],"performed":[53],"examine":[55],"existence":[57],"disease-free":[59,97],"endemic":[61,116],"equilibria,":[62],"basic":[65],"reproduction":[66],"number":[67],"R0":[68,93,108],"derived":[70],"using":[71],"next":[73],"generation":[74],"matrix":[75],"approach.":[76],"Numerical":[77],"simulations":[78],"are":[79,150],"conducted":[80],"illustrate":[82],"behavior":[84],"system":[87,112],"over":[88],"time,":[89],"confirming":[90],"that":[91,133,141],"when":[92,107],"<":[94],"1,":[95,110],"equilibrium":[98],"globally":[100],"stable,":[101],"leading":[102],"eradication.":[105],"However,":[106],">":[109],"shifts":[113],"an":[115],"equilibrium,":[117],"maintaining":[118],"persistent":[119],"infection.":[120],"Sensitivity":[121],"highlights.":[123],"key":[124],"parameters,":[125],"such":[126],"as":[127],"contact":[128],"rates":[129],"recovery":[131],"rates,":[132],"significantly":[134],"influence":[135],"dynamics.":[137],"results":[139],"suggest":[140],"effective":[142],"vaccination,":[143],"improved":[144],"sanitation,":[145],"measures":[149],"critical":[151],"reducing":[153],"spread":[155],"fever.":[158],"provides":[161],"valuable":[163],"framework":[164],"understanding":[166],"guiding":[170],"public":[171],"health":[172],"interventions.":[173]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2026-01-25T00:00:00"}