{"id":"https://openalex.org/W7124474804","doi":"https://doi.org/10.1155/cric/6816373","title":"When Patent Foramen Ovale (PFO) Can Cause Trouble\u2014A Misplacement of Pacemaker Lead Into the Left Ventricle","display_name":"When Patent Foramen Ovale (PFO) Can Cause Trouble\u2014A Misplacement of Pacemaker Lead Into the Left Ventricle","publication_year":2026,"publication_date":"2026-01-01","ids":{"openalex":"https://openalex.org/W7124474804","doi":"https://doi.org/10.1155/cric/6816373","pmid":"https://pubmed.ncbi.nlm.nih.gov/41550913","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/12809048"},"language":"en","primary_location":{"id":"doi:10.1155/cric/6816373","doi":"https://doi.org/10.1155/cric/6816373","is_oa":true,"landing_page_url":"https://doi.org/10.1155/cric/6816373","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1155/cric/6816373","source":{"id":"https://openalex.org/S2764744020","display_name":"Case Reports in Cardiology","issn_l":"2090-6404","issn":["2090-6404","2090-6412"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","poland-20","russia-white-list-4"],"host_organization":"https://openalex.org/P4310319869","host_organization_name":"Hindawi Publishing Corporation","host_organization_lineage":["https://openalex.org/P4310319869","https://openalex.org/P4310320595"],"host_organization_lineage_names":["Hindawi Publishing Corporation","Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Case Reports in Cardiology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1155/cric/6816373","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5084681870","display_name":"Ayman Helal","orcid":"https://orcid.org/0000-0001-5321-4377","observed_orcids":["https://orcid.org/0000-0001-5321-4377"]},"institutions":[{"id":"https://openalex.org/I2801415944","display_name":"Kettering General Hospital","ror":"https://ror.org/032kmqj66","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2801415944","https://openalex.org/I4210167175"]},{"id":"https://openalex.org/I4210167175","display_name":"Kettering General Hospital NHS Trust","ror":"https://ror.org/05xh7ac43","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I4210167175"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Ayman Helal","raw_affiliation_strings":["Department of Cardiology, Kettering General Hospital, University Hospitals of Northamptonshire, Kettering, Northamptonshire, UK, nhs.uk"],"raw_orcid":"https://orcid.org/0000-0001-5321-4377","affiliations":[{"raw_affiliation_string":"Department of Cardiology, Kettering General Hospital, University Hospitals of Northamptonshire, Kettering, Northamptonshire, UK, nhs.uk","institution_ids":["https://openalex.org/I2801415944","https://openalex.org/I4210167175"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003830346","display_name":"Ibrahim Antoun","orcid":"https://orcid.org/0000-0002-4374-7476","observed_orcids":["https://orcid.org/0000-0002-4374-7476"]},"institutions":[{"id":"https://openalex.org/I153648349","display_name":"University of Leicester","ror":"https://ror.org/04h699437","country_code":"GB","type":"education","lineage":["https://openalex.org/I153648349"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Ibrahim Antoun","raw_affiliation_strings":["Department of Cardiovascular Science, University of Leicester, Leicester, Leicestershire, UK, le.ac.uk"],"raw_orcid":"https://orcid.org/0000-0002-4374-7476","affiliations":[{"raw_affiliation_string":"Department of Cardiovascular Science, University of Leicester, Leicester, Leicestershire, UK, le.ac.uk","institution_ids":["https://openalex.org/I153648349"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5123729858","display_name":"Mohammed El-din","orcid":"https://orcid.org/0000-0001-6808-1650","observed_orcids":["https://orcid.org/0000-0001-6808-1650"]},"institutions":[{"id":"https://openalex.org/I2801415944","display_name":"Kettering General Hospital","ror":"https://ror.org/032kmqj66","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2801415944","https://openalex.org/I4210167175"]},{"id":"https://openalex.org/I4210167175","display_name":"Kettering General Hospital NHS Trust","ror":"https://ror.org/05xh7ac43","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I4210167175"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Mohammed El-Din","raw_affiliation_strings":["Department of Cardiology, Kettering General Hospital, University Hospitals of Northamptonshire, Kettering, Northamptonshire, UK, nhs.uk"],"raw_orcid":"https://orcid.org/0000-0001-6808-1650","affiliations":[{"raw_affiliation_string":"Department of Cardiology, Kettering General Hospital, University Hospitals of Northamptonshire, Kettering, Northamptonshire, UK, nhs.uk","institution_ids":["https://openalex.org/I2801415944","https://openalex.org/I4210167175"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5101034637","display_name":"Mohsin Farooq","orcid":"https://orcid.org/0000-0003-0011-2291","observed_orcids":["https://orcid.org/0000-0003-0011-2291"]},"institutions":[{"id":"https://openalex.org/I2801415944","display_name":"Kettering General Hospital","ror":"https://ror.org/032kmqj66","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2801415944","https://openalex.org/I4210167175"]},{"id":"https://openalex.org/I4210167175","display_name":"Kettering General Hospital NHS Trust","ror":"https://ror.org/05xh7ac43","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I4210167175"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Mohsin Farooq","raw_affiliation_strings":["Department of Cardiology, Kettering General Hospital, University Hospitals of Northamptonshire, Kettering, Northamptonshire, UK, nhs.uk"],"raw_orcid":"https://orcid.org/0000-0003-0011-2291","affiliations":[{"raw_affiliation_string":"Department of Cardiology, Kettering General Hospital, University Hospitals of Northamptonshire, Kettering, Northamptonshire, UK, nhs.uk","institution_ids":["https://openalex.org/I2801415944","https://openalex.org/I4210167175"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5003830346"],"corresponding_institution_ids":["https://openalex.org/I153648349"],"apc_list":{"value":790,"currency":"USD","value_usd":790},"apc_paid":{"value":790,"currency":"USD","value_usd":790},"fwci":7.002,"has_fulltext":true,"cited_by_count":2,"citation_normalized_percentile":{"value":0.95042183,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":95,"max":96},"biblio":{"volume":"2026","issue":"1","first_page":"6816373","last_page":"6816373"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10598","display_name":"Cardiac pacing and defibrillation studies","score":0.9804999828338623,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10598","display_name":"Cardiac pacing and defibrillation studies","score":0.9804999828338623,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11579","display_name":"Cardiovascular and Diving-Related Complications","score":0.014600000344216824,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11551","display_name":"Infective Endocarditis Diagnosis and Management","score":0.0012000000569969416,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/patent-foramen-ovale","display_name":"patent foramen ovale","score":0.9959999918937683},{"id":"https://openalex.org/keywords/left-ventricular-pacing","display_name":"left ventricular pacing","score":0.9070000052452087},{"id":"https://openalex.org/keywords/intracardiac-shunt","display_name":"intracardiac shunt","score":0.9020000100135803},{"id":"https://openalex.org/keywords/lead-extraction","display_name":"lead extraction","score":0.5329999923706055},{"id":"https://openalex.org/keywords/fluoroscopy","display_name":"fluoroscopy","score":0.5899999737739563},{"id":"https://openalex.org/keywords/left-anterior-oblique-projection","display_name":"left anterior oblique projection","score":0.9110000133514404},{"id":"https://openalex.org/keywords/permanent-pacemaker-implantation","display_name":"permanent pacemaker implantation","score":0.7590000033378601},{"id":"https://openalex.org/keywords/bioprosthetic-aortic-valve","display_name":"bioprosthetic aortic valve","score":0.7639999985694885}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9409000277519226},{"id":"https://openalex.org/C2776893843","wikidata":"https://www.wikidata.org/wiki/Q757749","display_name":"Patent foramen ovale","level":3,"score":0.8012999892234802},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.7354000210762024},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.699999988079071},{"id":"https://openalex.org/C2778921608","wikidata":"https://www.wikidata.org/wiki/Q2002035","display_name":"Ventricle","level":2,"score":0.6668000221252441},{"id":"https://openalex.org/C80093799","wikidata":"https://www.wikidata.org/wiki/Q366155","display_name":"Intracardiac injection","level":2,"score":0.4578000009059906},{"id":"https://openalex.org/C2778259205","wikidata":"https://www.wikidata.org/wiki/Q629460","display_name":"Coronary sinus","level":2,"score":0.4507000148296356},{"id":"https://openalex.org/C2777910003","wikidata":"https://www.wikidata.org/wiki/Q1707292","display_name":"Asymptomatic","level":2,"score":0.3799999952316284},{"id":"https://openalex.org/C111773187","wikidata":"https://www.wikidata.org/wiki/Q1969239","display_name":"QRS complex","level":2,"score":0.3659999966621399},{"id":"https://openalex.org/C2779987240","wikidata":"https://www.wikidata.org/wiki/Q767116","display_name":"Foramen ovale (heart)","level":4,"score":0.3594000041484833},{"id":"https://openalex.org/C2780007028","wikidata":"https://www.wikidata.org/wiki/Q2343082","display_name":"Stenosis","level":2,"score":0.3400999903678894},{"id":"https://openalex.org/C2777093003","wikidata":"https://www.wikidata.org/wiki/Q6508345","display_name":"Lead (geology)","level":2,"score":0.335099995136261},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.3278999924659729},{"id":"https://openalex.org/C2775872228","wikidata":"https://www.wikidata.org/wiki/Q82504","display_name":"Endocarditis","level":2,"score":0.32179999351501465},{"id":"https://openalex.org/C2780714102","wikidata":"https://www.wikidata.org/wiki/Q616071","display_name":"Aortic valve","level":2,"score":0.3075999915599823},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.2973000109195709},{"id":"https://openalex.org/C2777543888","wikidata":"https://www.wikidata.org/wiki/Q369939","display_name":"Mitral valve","level":2,"score":0.2903999984264374},{"id":"https://openalex.org/C2776805002","wikidata":"https://www.wikidata.org/wiki/Q614984","display_name":"Fluoroscopy","level":2,"score":0.25270000100135803},{"id":"https://openalex.org/C2776035437","wikidata":"https://www.wikidata.org/wiki/Q1144114","display_name":"Embolization","level":2,"score":0.25040000677108765}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1155/cric/6816373","doi":"https://doi.org/10.1155/cric/6816373","is_oa":true,"landing_page_url":"https://doi.org/10.1155/cric/6816373","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1155/cric/6816373","source":{"id":"https://openalex.org/S2764744020","display_name":"Case Reports in Cardiology","issn_l":"2090-6404","issn":["2090-6404","2090-6412"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","poland-20","russia-white-list-4"],"host_organization":"https://openalex.org/P4310319869","host_organization_name":"Hindawi Publishing Corporation","host_organization_lineage":["https://openalex.org/P4310319869","https://openalex.org/P4310320595"],"host_organization_lineage_names":["Hindawi Publishing Corporation","Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Case Reports in Cardiology","raw_type":"journal-article"},{"id":"pmid:41550913","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/41550913","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Case reports in cardiology","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:12809048","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12809048/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Case Rep Cardiol","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1155/cric/6816373","doi":"https://doi.org/10.1155/cric/6816373","is_oa":true,"landing_page_url":"https://doi.org/10.1155/cric/6816373","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1155/cric/6816373","source":{"id":"https://openalex.org/S2764744020","display_name":"Case Reports in Cardiology","issn_l":"2090-6404","issn":["2090-6404","2090-6412"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","poland-20","russia-white-list-4"],"host_organization":"https://openalex.org/P4310319869","host_organization_name":"Hindawi Publishing Corporation","host_organization_lineage":["https://openalex.org/P4310319869","https://openalex.org/P4310320595"],"host_organization_lineage_names":["Hindawi Publishing Corporation","Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Case Reports in Cardiology","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9907000064849854,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Case Report","id":"https://openalex.org/study-designs/case-report"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7124474804.pdf","grobid_xml":"https://content.openalex.org/works/W7124474804.grobid-xml"},"referenced_works_count":7,"referenced_works":["https://openalex.org/W2055653327","https://openalex.org/W2972627770","https://openalex.org/W4295709254","https://openalex.org/W4384764241","https://openalex.org/W4402011285","https://openalex.org/W4409314684","https://openalex.org/W4409698868"],"related_works":["https://openalex.org/W4388928557","https://openalex.org/W4409698868","https://openalex.org/W2064246812","https://openalex.org/W2504440991","https://openalex.org/W1524436190","https://openalex.org/W1976984513","https://openalex.org/W3214911880","https://openalex.org/W2019983991","https://openalex.org/W1986803115","https://openalex.org/W2522508569"],"abstract_inverted_index":{"Misplacement":[0],"of":[1,52,86,88,126,136,186,189,253],"pacemakers":[2],"lead":[3,98,148,204,243],"into":[4,152],"the":[5,96,107,110,153,167,184],"left":[6,168],"ventricle":[7,155],"(LV)":[8],"is":[9,31,215],"a":[10,24,44,50,101,117],"rare":[11],"but":[12],"clinically":[13],"important":[14],"complication,":[15],"often":[16],"facilitated":[17],"by":[18,174,227],"unrecognized":[19,249],"intracardiac":[20],"shunts":[21],"such":[22],"as":[23,84],"patent":[25],"foramen":[26],"ovale":[27],"(PFO).":[28],"Early":[29],"recognition":[30,221],"essential":[32],"to":[33,202],"avoid":[34],"systemic":[35,137],"embolization":[36],"and":[37,66,103,144,150,173,179,199,222,229,257,261,267],"ensure":[38],"safe":[39],"device":[40],"function.":[41],"We":[42],"report":[43],"man":[45],"in":[46,106,246],"his":[47,89],"70s":[48],"with":[49,133,142,224,248,259],"background":[51],"bioprosthetic":[53],"aortic":[54,90],"valve":[55,91],"replacement,":[56],"coronary":[57],"bypass":[58],"grafting,":[59],"hypertension,":[60],"chronic":[61],"kidney":[62],"disease,":[63,65],"Parkinson's":[64],"prostate":[67],"cancer,":[68],"who":[69],"underwent":[70,146],"permanent":[71],"pacemaker":[72],"implantation":[73,196],"for":[74,240],"symptomatic":[75],"sinus":[76],"pauses.":[77],"Follow-up":[78],"echocardiography":[79,262],"1":[80],"year":[81],"later,":[82],"performed":[83],"part":[85],"surveillance":[87],"prosthesis,":[92],"unexpectedly":[93],"revealed":[94],"that":[95],"ventricular":[97],"had":[99],"crossed":[100],"PFO":[102],"was":[104,140,160],"positioned":[105],"LV":[108,127,242],"via":[109],"mitral":[111],"valve.":[112],"His":[113],"12-lead":[114],"ECG":[115,191,260],"demonstrated":[116],"right":[118,154],"bundle":[119],"branch":[120],"block-like":[121],"paced":[122,190],"morphology,":[123,192],"raising":[124],"suspicion":[125],"pacing.":[128,219],"The":[129],"patient":[130],"remained":[131],"asymptomatic":[132],"no":[134],"evidence":[135],"embolization.":[138],"He":[139],"anticoagulated":[141],"apixaban":[143],"subsequently":[145],"successful":[147],"extraction":[149,228],"repositioning":[151],"(RV).":[156],"Correct":[157],"RV":[158,218],"placement":[159],"confirmed":[161],"using":[162],"multiple":[163,254],"fluoroscopic":[164,193,255],"views,":[165],"particularly":[166,245],"anterior":[169],"oblique":[170],"(LAO)":[171],"projection":[172],"postprocedure":[175],"ECG,":[176],"chest":[177],"x-ray,":[178],"echocardiogram.":[180],"This":[181],"case":[182],"underlines":[183],"importance":[185],"careful":[187],"assessment":[188],"views":[194],"during":[195,217],"(especially":[197],"LAO),":[198],"postimplant":[200],"imaging":[201],"confirm":[203],"location.":[205],"Suspicion":[206],"should":[207,237],"be":[208],"raised":[209],"when":[210],"an":[211],"RBBB-like":[212],"QRS":[213],"morphology":[214],"observed":[216],"Timely":[220],"management":[223],"anticoagulation,":[225],"followed":[226],"repositioning,":[230],"can":[231,263],"prevent":[232],"potentially":[233],"devastating":[234],"complications.":[235],"Operators":[236],"remain":[238],"vigilant":[239],"inadvertent":[241],"placement,":[244],"patients":[247],"PFO.":[250],"Routine":[251],"use":[252],"projections":[256],"correlation":[258],"aid":[264],"early":[265],"diagnosis":[266],"improve":[268],"procedural":[269],"safety.":[270]},"counts_by_year":[{"year":2026,"cited_by_count":2}],"updated_date":"2026-11-11T12:16:26.678958","created_date":"2026-01-17T00:00:00"}