{"id":"https://openalex.org/W7124311247","doi":"https://doi.org/10.1186/s12964-026-02673-x","title":"Mitochondrial homeostasis meets novel programmed cell death: crosstalk mechanisms underlying cardiovascular diseases progression","display_name":"Mitochondrial homeostasis meets novel programmed cell death: crosstalk mechanisms underlying cardiovascular diseases progression","publication_year":2026,"publication_date":"2026-01-15","ids":{"openalex":"https://openalex.org/W7124311247","doi":"https://doi.org/10.1186/s12964-026-02673-x","pmid":"https://pubmed.ncbi.nlm.nih.gov/41540474"},"language":"en","primary_location":{"id":"doi:10.1186/s12964-026-02673-x","doi":"https://doi.org/10.1186/s12964-026-02673-x","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12964-026-02673-x","pdf_url":null,"source":{"id":"https://openalex.org/S138104925","display_name":"Cell Communication and Signaling","issn_l":"1478-811X","issn":["1478-811X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell Communication and Signaling","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1186/s12964-026-02673-x","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5123167108","display_name":"Meng Li","orcid":"https://orcid.org/0000-0003-2090-6013","observed_orcids":["https://orcid.org/0000-0003-2090-6013"]},"institutions":[{"id":"https://openalex.org/I131434179","display_name":"Nanjing University of Chinese Medicine","ror":"https://ror.org/04523zj19","country_code":"CN","type":"education","lineage":["https://openalex.org/I131434179"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Meng Li","raw_affiliation_strings":["School of Chinese Medicine, Nanjing University of Chinese Medicine, Nanjing, Jiangsu, China. zhongyilimeng@163.com"],"raw_orcid":"https://orcid.org/0000-0003-2090-6013","affiliations":[{"raw_affiliation_string":"School of Chinese Medicine, Nanjing University of Chinese Medicine, Nanjing, Jiangsu, China. zhongyilimeng@163.com","institution_ids":["https://openalex.org/I131434179"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5123087764","display_name":"Yue Zhang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I131434179","display_name":"Nanjing University of Chinese Medicine","ror":"https://ror.org/04523zj19","country_code":"CN","type":"education","lineage":["https://openalex.org/I131434179"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yue Zhang","raw_affiliation_strings":["School of Integrative Medicine, Nanjing University of Chinese Medicine, Nanjing, Jiangsu, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Integrative Medicine, Nanjing University of Chinese Medicine, Nanjing, Jiangsu, China","institution_ids":["https://openalex.org/I131434179"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100755025","display_name":"Yue Hu","orcid":"https://orcid.org/0000-0002-9814-0233","observed_orcids":["https://orcid.org/0000-0002-9814-0233"]},"institutions":[{"id":"https://openalex.org/I131434179","display_name":"Nanjing University of Chinese Medicine","ror":"https://ror.org/04523zj19","country_code":"CN","type":"education","lineage":["https://openalex.org/I131434179"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yue Hu","raw_affiliation_strings":["School of Integrative Medicine, Nanjing University of Chinese Medicine, Nanjing, Jiangsu, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Integrative Medicine, Nanjing University of Chinese Medicine, Nanjing, Jiangsu, China","institution_ids":["https://openalex.org/I131434179"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5105645517","display_name":"Yiqi QIN","orcid":"https://orcid.org/0009-0003-0986-4470","observed_orcids":["https://orcid.org/0009-0003-0986-4470"]},"institutions":[{"id":"https://openalex.org/I131434179","display_name":"Nanjing University of Chinese Medicine","ror":"https://ror.org/04523zj19","country_code":"CN","type":"education","lineage":["https://openalex.org/I131434179"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yiqi Qin","raw_affiliation_strings":["School of Chinese Medicine, Nanjing University of Chinese Medicine, Nanjing, Jiangsu, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Chinese Medicine, Nanjing University of Chinese Medicine, Nanjing, Jiangsu, China","institution_ids":["https://openalex.org/I131434179"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5123105862","display_name":"Yawei Zheng","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I131434179","display_name":"Nanjing University of Chinese Medicine","ror":"https://ror.org/04523zj19","country_code":"CN","type":"education","lineage":["https://openalex.org/I131434179"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yawei Zheng","raw_affiliation_strings":["School of Chinese Medicine, Nanjing University of Chinese Medicine, Nanjing, Jiangsu, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Chinese Medicine, Nanjing University of Chinese Medicine, Nanjing, Jiangsu, China","institution_ids":["https://openalex.org/I131434179"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053953111","display_name":"Shichao Lv","orcid":"https://orcid.org/0000-0002-0650-3843","observed_orcids":["https://orcid.org/0000-0002-0650-3843"]},"institutions":[{"id":"https://openalex.org/I12411659","display_name":"Tianjin University of Traditional Chinese Medicine","ror":"https://ror.org/05dfcz246","country_code":"CN","type":"education","lineage":["https://openalex.org/I12411659"]},{"id":"https://openalex.org/I4210130148","display_name":"First Teaching Hospital of Tianjin University of Traditional Chinese Medicine","ror":"https://ror.org/02fsmcz03","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210130148"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shichao Lv","raw_affiliation_strings":["National Clinical Research Center of Acupuncture and Moxibustion, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Clinical Research Center of Acupuncture and Moxibustion, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, China","institution_ids":["https://openalex.org/I12411659","https://openalex.org/I4210130148"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100696430","display_name":"Junping Zhang","orcid":"https://orcid.org/0000-0002-7271-8615","observed_orcids":["https://orcid.org/0000-0002-7271-8615"]},"institutions":[{"id":"https://openalex.org/I12411659","display_name":"Tianjin University of Traditional Chinese Medicine","ror":"https://ror.org/05dfcz246","country_code":"CN","type":"education","lineage":["https://openalex.org/I12411659"]},{"id":"https://openalex.org/I4210130148","display_name":"First Teaching Hospital of Tianjin University of Traditional Chinese Medicine","ror":"https://ror.org/02fsmcz03","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210130148"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Junping Zhang","raw_affiliation_strings":["National Clinical Research Center of Acupuncture and Moxibustion, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Clinical Research Center of Acupuncture and Moxibustion, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, China","institution_ids":["https://openalex.org/I12411659","https://openalex.org/I4210130148"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5123167108"],"corresponding_institution_ids":["https://openalex.org/I131434179"],"apc_list":{"value":3390,"currency":"USD","value_usd":3390},"apc_paid":{"value":3390,"currency":"USD","value_usd":3390},"fwci":16.9618,"has_fulltext":false,"cited_by_count":9,"citation_normalized_percentile":{"value":0.99356135,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":98,"max":99},"biblio":{"volume":"24","issue":"1","first_page":"100","last_page":"100"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10301","display_name":"Mitochondrial Function and Pathology","score":0.5889000296592712,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10301","display_name":"Mitochondrial Function and Pathology","score":0.5889000296592712,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10294","display_name":"Cell death mechanisms and regulation","score":0.2328999936580658,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10587","display_name":"Autophagy in Disease and Therapy","score":0.16169999539852142,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/mitochondrial-homeostasis","display_name":"mitochondrial homeostasis","score":0.9990000128746033},{"id":"https://openalex.org/keywords/mitochondrial-quality-control","display_name":"mitochondrial quality control","score":0.7979999780654907},{"id":"https://openalex.org/keywords/programmed-cell-death","display_name":"programmed cell death","score":0.8320000171661377},{"id":"https://openalex.org/keywords/ferroptosis","display_name":"ferroptosis","score":0.9700000286102295},{"id":"https://openalex.org/keywords/cuproptosis","display_name":"cuproptosis","score":1.0},{"id":"https://openalex.org/keywords/pyroptosis","display_name":"pyroptosis","score":1.0},{"id":"https://openalex.org/keywords/necroptosis","display_name":"necroptosis","score":1.0},{"id":"https://openalex.org/keywords/netosis","display_name":"NETosis","score":0.996999979019165},{"id":"https://openalex.org/keywords/disulfidptosis","display_name":"disulfidptosis","score":0.996999979019165},{"id":"https://openalex.org/keywords/cardiomyocyte-death","display_name":"cardiomyocyte death","score":0.7889999747276306},{"id":"https://openalex.org/keywords/mitochondrial-dynamics","display_name":"mitochondrial dynamics","score":0.6919999718666077},{"id":"https://openalex.org/keywords/mitophagy","display_name":"mitophagy","score":0.9860000014305115},{"id":"https://openalex.org/keywords/cardiovascular-disease","display_name":"cardiovascular disease","score":0.6869999766349792},{"id":"https://openalex.org/keywords/lipid-peroxidation","display_name":"lipid peroxidation","score":0.9750000238418579},{"id":"https://openalex.org/keywords/inflammasome","display_name":"inflammasome","score":0.8889999985694885},{"id":"https://openalex.org/keywords/oxidative-stress","display_name":"oxidative stress","score":0.7860000133514404},{"id":"https://openalex.org/keywords/therapeutic-target","display_name":"therapeutic target","score":0.9589999914169312}],"concepts":[{"id":"https://openalex.org/C169822122","wikidata":"https://www.wikidata.org/wiki/Q230187","display_name":"Crosstalk","level":2,"score":0.8560000061988831},{"id":"https://openalex.org/C2779324830","wikidata":"https://www.wikidata.org/wiki/Q1806192","display_name":"Mitophagy","level":4,"score":0.8021000027656555},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.6672000288963318},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6607999801635742},{"id":"https://openalex.org/C28859421","wikidata":"https://www.wikidata.org/wiki/Q39572","display_name":"Mitochondrion","level":2,"score":0.6464999914169312},{"id":"https://openalex.org/C31573885","wikidata":"https://www.wikidata.org/wiki/Q304484","display_name":"Programmed cell death","level":3,"score":0.6029000282287598},{"id":"https://openalex.org/C111491248","wikidata":"https://www.wikidata.org/wiki/Q18033821","display_name":"DNAJA3","level":5,"score":0.5691999793052673},{"id":"https://openalex.org/C203522944","wikidata":"https://www.wikidata.org/wiki/Q288322","display_name":"Autophagy","level":3,"score":0.5475999712944031},{"id":"https://openalex.org/C2991704936","wikidata":"https://www.wikidata.org/wiki/Q1057","display_name":"Cell metabolism","level":3,"score":0.5360999703407288},{"id":"https://openalex.org/C163950672","wikidata":"https://www.wikidata.org/wiki/Q14905375","display_name":"mitochondrial fusion","level":4,"score":0.43939998745918274},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.4374000132083893},{"id":"https://openalex.org/C2777229759","wikidata":"https://www.wikidata.org/wiki/Q6881848","display_name":"Mitochondrial biogenesis","level":3,"score":0.3815000057220459},{"id":"https://openalex.org/C17619807","wikidata":"https://www.wikidata.org/wiki/Q6881852","display_name":"Mitochondrial fission","level":3,"score":0.3774000108242035},{"id":"https://openalex.org/C94030615","wikidata":"https://www.wikidata.org/wiki/Q3346925","display_name":"Necroptosis","level":4,"score":0.362199991941452},{"id":"https://openalex.org/C63645605","wikidata":"https://www.wikidata.org/wiki/Q103191","display_name":"Homeostasis","level":2,"score":0.3594000041484833},{"id":"https://openalex.org/C62478195","wikidata":"https://www.wikidata.org/wiki/Q828130","display_name":"Signal transduction","level":2,"score":0.33660000562667847},{"id":"https://openalex.org/C2776804853","wikidata":"https://www.wikidata.org/wiki/Q18045837","display_name":"PINK1","level":5,"score":0.3246000111103058},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.31839999556541443},{"id":"https://openalex.org/C189014844","wikidata":"https://www.wikidata.org/wiki/Q189118","display_name":"Cell type","level":3,"score":0.30880001187324524},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.295199990272522},{"id":"https://openalex.org/C2781452922","wikidata":"https://www.wikidata.org/wiki/Q2892805","display_name":"Proteostasis","level":2,"score":0.2856000065803528},{"id":"https://openalex.org/C150555746","wikidata":"https://www.wikidata.org/wiki/Q210973","display_name":"Cell signaling","level":3,"score":0.2743000090122223},{"id":"https://openalex.org/C190283241","wikidata":"https://www.wikidata.org/wiki/Q14599311","display_name":"Apoptosis","level":2,"score":0.2727000117301941},{"id":"https://openalex.org/C2777209026","wikidata":"https://www.wikidata.org/wiki/Q412405","display_name":"Inflammasome","level":3,"score":0.26989999413490295},{"id":"https://openalex.org/C163952510","wikidata":"https://www.wikidata.org/wiki/Q5058196","display_name":"Cell fate determination","level":4,"score":0.26190000772476196},{"id":"https://openalex.org/C24586158","wikidata":"https://www.wikidata.org/wiki/Q27075","display_name":"Mitochondrial DNA","level":3,"score":0.26089999079704285},{"id":"https://openalex.org/C57600042","wikidata":"https://www.wikidata.org/wiki/Q227564","display_name":"Oxidative phosphorylation","level":2,"score":0.2547000050544739}],"mesh":[{"descriptor_ui":"D000098560","descriptor_name":"Disulfidptosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000098560","descriptor_name":"Disulfidptosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000099217","descriptor_name":"Cuproptosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000099217","descriptor_name":"Cuproptosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002318","descriptor_name":"Cardiovascular Diseases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D002318","descriptor_name":"Cardiovascular Diseases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D002318","descriptor_name":"Cardiovascular Diseases","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D002318","descriptor_name":"Cardiovascular Diseases","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D006706","descriptor_name":"Homeostasis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006706","descriptor_name":"Homeostasis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008928","descriptor_name":"Mitochondria","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D008928","descriptor_name":"Mitochondria","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D015398","descriptor_name":"Signal Transduction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015398","descriptor_name":"Signal Transduction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017209","descriptor_name":"Apoptosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D017209","descriptor_name":"Apoptosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D018450","descriptor_name":"Disease Progression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D018450","descriptor_name":"Disease Progression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":5,"locations":[{"id":"doi:10.1186/s12964-026-02673-x","doi":"https://doi.org/10.1186/s12964-026-02673-x","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12964-026-02673-x","pdf_url":null,"source":{"id":"https://openalex.org/S138104925","display_name":"Cell Communication and Signaling","issn_l":"1478-811X","issn":["1478-811X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell Communication and Signaling","raw_type":"journal-article"},{"id":"pmid:41540474","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/41540474","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell communication and signaling : CCS","raw_type":"Journal Article"},{"id":"pmh:oai:europepmc.org:11696300","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/12888742","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:b8c0794309a941499c1cc9fc0c76f43c","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/b8c0794309a941499c1cc9fc0c76f43c","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Cell Communication and Signaling, Vol 24, Iss 1 (2026)","raw_type":"article"},{"id":"pmh:oai:pubmedcentral.nih.gov:12888742","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12888742/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Cell Commun Signal","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1186/s12964-026-02673-x","doi":"https://doi.org/10.1186/s12964-026-02673-x","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12964-026-02673-x","pdf_url":null,"source":{"id":"https://openalex.org/S138104925","display_name":"Cell Communication and Signaling","issn_l":"1478-811X","issn":["1478-811X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell Communication and Signaling","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9763000011444092}],"sustainable_development_goals_aurora":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.7621020078659058}],"study_designs":[],"awards":[{"id":"https://openalex.org/G8827560126","display_name":null,"funder_award_id":"2021M701768","funder_id":"https://openalex.org/F4320321543","funder_display_name":"China Postdoctoral Science Foundation"}],"funders":[{"id":"https://openalex.org/F4320321543","display_name":"China Postdoctoral Science Foundation","ror":"https://ror.org/0426zh255"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":121,"referenced_works":["https://openalex.org/W2231291760","https://openalex.org/W2758226562","https://openalex.org/W2775038098","https://openalex.org/W2791467192","https://openalex.org/W2894148464","https://openalex.org/W2961957758","https://openalex.org/W2985539554","https://openalex.org/W3005606800","https://openalex.org/W3011438913","https://openalex.org/W3012923032","https://openalex.org/W3028024251","https://openalex.org/W3042309757","https://openalex.org/W3095535158","https://openalex.org/W3096770937","https://openalex.org/W3128675734","https://openalex.org/W3134354987","https://openalex.org/W3146217822","https://openalex.org/W3161725605","https://openalex.org/W3174194251","https://openalex.org/W3178107479","https://openalex.org/W3193170425","https://openalex.org/W3199933318","https://openalex.org/W4200565862","https://openalex.org/W4205210641","https://openalex.org/W4205401377","https://openalex.org/W4207055357","https://openalex.org/W4213233537","https://openalex.org/W4220750983","https://openalex.org/W4220821783","https://openalex.org/W4221115671","https://openalex.org/W4225289119","https://openalex.org/W4280512700","https://openalex.org/W4280584556","https://openalex.org/W4280609211","https://openalex.org/W4280609459","https://openalex.org/W4280653852","https://openalex.org/W4281648551","https://openalex.org/W4282940384","https://openalex.org/W4284879360","https://openalex.org/W4289730992","https://openalex.org/W4297239236","https://openalex.org/W4306816573","https://openalex.org/W4308208034","https://openalex.org/W4308771485","https://openalex.org/W4310835565","https://openalex.org/W4310947677","https://openalex.org/W4311676948","https://openalex.org/W4313298540","https://openalex.org/W4319310752","https://openalex.org/W4321254217","https://openalex.org/W4322421522","https://openalex.org/W4376131839","https://openalex.org/W4381469200","https://openalex.org/W4381612979","https://openalex.org/W4382359367","https://openalex.org/W4383226835","https://openalex.org/W4384695119","https://openalex.org/W4385782388","https://openalex.org/W4386448978","https://openalex.org/W4387407123","https://openalex.org/W4388200220","https://openalex.org/W4388283199","https://openalex.org/W4388500684","https://openalex.org/W4388516697","https://openalex.org/W4389039993","https://openalex.org/W4389744388","https://openalex.org/W4390233381","https://openalex.org/W4390754712","https://openalex.org/W4391017384","https://openalex.org/W4391310772","https://openalex.org/W4391806996","https://openalex.org/W4391896678","https://openalex.org/W4392370058","https://openalex.org/W4392473174","https://openalex.org/W4392760933","https://openalex.org/W4392773060","https://openalex.org/W4394684549","https://openalex.org/W4394770551","https://openalex.org/W4395674836","https://openalex.org/W4395702450","https://openalex.org/W4396222140","https://openalex.org/W4396664373","https://openalex.org/W4396767940","https://openalex.org/W4396857827","https://openalex.org/W4398231688","https://openalex.org/W4399606092","https://openalex.org/W4399861320","https://openalex.org/W4399898765","https://openalex.org/W4401044035","https://openalex.org/W4401794028","https://openalex.org/W4401820619","https://openalex.org/W4402640384","https://openalex.org/W4402786073","https://openalex.org/W4403011549","https://openalex.org/W4403073137","https://openalex.org/W4403519527","https://openalex.org/W4403987985","https://openalex.org/W4404200547","https://openalex.org/W4405306985","https://openalex.org/W4405624965","https://openalex.org/W4405842167","https://openalex.org/W4406117253","https://openalex.org/W4406320690","https://openalex.org/W4406518865","https://openalex.org/W4407878649","https://openalex.org/W4408095187","https://openalex.org/W4408548219","https://openalex.org/W4408632941","https://openalex.org/W4408772741","https://openalex.org/W4409265688","https://openalex.org/W4409312894","https://openalex.org/W4409377770","https://openalex.org/W4409655641","https://openalex.org/W4409791912","https://openalex.org/W4410350895","https://openalex.org/W4410593542","https://openalex.org/W4411178696","https://openalex.org/W4411511186","https://openalex.org/W4411571209","https://openalex.org/W4411969560","https://openalex.org/W4413105184"],"related_works":[],"abstract_inverted_index":{"Mitochondrial":[0],"homeostasis":[1,176],"is":[2],"essential":[3],"for":[4,111,161],"cardiomyocyte":[5,154,211],"survival":[6],"and":[7,27,39,55,59,83,127,140,152,165,177,187,200,221],"optimal":[8],"cardiac":[9,222],"function.":[10,223],"Recent":[11],"studies":[12],"have":[13],"revealed":[14],"that":[15,143],"novel":[16,178],"forms":[17],"of":[18,47,79],"programmed":[19,80,179],"cell":[20,81,98,101,180],"death\u2014including":[21],"ferroptosis,":[22],"cuproptosis,":[23,196],"pyroptosis,":[24,197],"necroptosis,":[25,198],"NETosis,":[26,199],"disulfidptosis\u2014interact":[28],"closely":[29],"with":[30,203],"mitochondrial":[31,37,52,84,92,105,150,175,188,207,219],"quality":[32,85,208],"control":[33,209],"mechanisms,":[34],"such":[35],"as":[36],"dynamics":[38,189],"mitophagy.":[40],"This":[41],"review":[42],"provides":[43],"a":[44],"comprehensive":[45],"overview":[46],"the":[48,74,88,172],"molecular":[49,141],"pathways":[50,103,164,216],"underlying":[51],"fusion,":[53],"fission,":[54],"selective":[56],"autophagic":[57],"clearance,":[58],"highlights":[60],"how":[61],"disturbances":[62],"in":[63,182],"these":[64,133,163,215],"processes":[65],"contribute":[66],"to":[67,97,148,170],"cardiovascular":[68,183,191],"disease":[69,192],"progression.":[70,193],"We":[71],"further":[72],"discuss":[73,158],"crosstalk":[75,202],"between":[76,174],"each":[77],"form":[78],"death":[82,102,181],"control,":[86],"emphasizing":[87],"bidirectional":[89],"influence":[90,190],"whereby":[91],"dysfunction":[93],"can":[94],"sensitize":[95],"cardiomyocytes":[96],"death,":[99],"while":[100],"exacerbate":[104],"injury.":[106,212],"Mechanistic":[107],"insights":[108],"are":[109],"provided":[110],"ferroptosis-driven":[112],"lipid":[113],"peroxidation,":[114],"cuproptosis-associated":[115],"copper":[116],"dysregulation,":[117],"pyroptotic":[118],"inflammasome":[119],"activation,":[120],"necroptotic":[121],"receptor-interacting":[122],"signaling,":[123],"NETosis-mediated":[124],"oxidative":[125],"stress,":[126],"disulfidptosis-induced":[128],"cytoskeletal":[129],"collapse.":[130],"By":[131],"integrating":[132],"findings,":[134],"we":[135,157],"identify":[136],"critical":[137],"regulatory":[138],"nodes":[139],"hubs":[142],"represent":[144],"potential":[145],"therapeutic":[146],"targets":[147],"preserve":[149,218],"integrity":[151,220],"prevent":[153],"loss.":[155],"Finally,":[156],"emerging":[159],"strategies":[160],"modulating":[162],"outline":[166],"future":[167],"research":[168],"directions":[169],"clarify":[171],"interplay":[173],"pathology.":[184],"\u2022":[185,194,205,213],"Mitophagy":[186],"Ferroptosis,":[195],"disulfidptosis":[201],"mitochondria.":[204],"Disrupted":[206],"exacerbates":[210],"Targeting":[214],"may":[217]},"counts_by_year":[{"year":2026,"cited_by_count":9}],"updated_date":"2026-10-11T09:32:39.932853","created_date":"2026-01-16T00:00:00"}