{"id":"https://openalex.org/W7123680146","doi":"https://doi.org/10.1186/s13063-026-09437-5","title":"Initial supplementary oxygen concentration for moderate-late preterm infants receiving respiratory support in the delivery room: statistical analysis plan for the multicenter, cluster-randomized crossover AIROPLANE Trial","display_name":"Initial supplementary oxygen concentration for moderate-late preterm infants receiving respiratory support in the delivery room: statistical analysis plan for the multicenter, cluster-randomized crossover AIROPLANE Trial","publication_year":2026,"publication_date":"2026-01-14","ids":{"openalex":"https://openalex.org/W7123680146","doi":"https://doi.org/10.1186/s13063-026-09437-5","pmid":"https://pubmed.ncbi.nlm.nih.gov/41535893"},"language":"en","primary_location":{"id":"doi:10.1186/s13063-026-09437-5","doi":"https://doi.org/10.1186/s13063-026-09437-5","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s13063-026-09437-5","pdf_url":null,"source":{"id":"https://openalex.org/S109512841","display_name":"Trials","issn_l":"1745-6215","issn":["1745-6215"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Trials","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1186/s13063-026-09437-5","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5022537165","display_name":"Stacey Peart","orcid":"https://orcid.org/0000-0001-8315-8791","observed_orcids":["https://orcid.org/0000-0001-8315-8791","https://orcid.org/0009-0005-2989-7071"]},"institutions":[{"id":"https://openalex.org/I1331142282","display_name":"Royal Women's Hospital","ror":"https://ror.org/03grnna41","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I1331142282"]},{"id":"https://openalex.org/I165779595","display_name":"The University of Melbourne","ror":"https://ror.org/01ej9dk98","country_code":"AU","type":"education","lineage":["https://openalex.org/I165779595"]},{"id":"https://openalex.org/I4210150290","display_name":"Murdoch Children's Research Institute","ror":"https://ror.org/048fyec77","country_code":"AU","type":"nonprofit","lineage":["https://openalex.org/I4210150290"]}],"countries":["AU"],"is_corresponding":true,"raw_author_name":"Stacey Peart","raw_affiliation_strings":["Clinical Sciences, Murdoch Children's Research Institute, Melbourne, Australia. stacey.peart@thewomens.org.au","Department of Obstetrics, Gynaecology and Newborn Health, The University of Melbourne, Melbourne, Australia. stacey.peart@thewomens.org.au","Newborn Services and Newborn Research, Royal Women's Hospital, Melbourne, Australia. stacey.peart@thewomens.org.au"],"raw_orcid":"https://orcid.org/0000-0001-8315-8791","affiliations":[{"raw_affiliation_string":"Clinical Sciences, Murdoch Children's Research Institute, Melbourne, Australia. stacey.peart@thewomens.org.au","institution_ids":["https://openalex.org/I4210150290"]},{"raw_affiliation_string":"Department of Obstetrics, Gynaecology and Newborn Health, The University of Melbourne, Melbourne, Australia. stacey.peart@thewomens.org.au","institution_ids":["https://openalex.org/I165779595"]},{"raw_affiliation_string":"Newborn Services and Newborn Research, Royal Women's Hospital, Melbourne, Australia. stacey.peart@thewomens.org.au","institution_ids":["https://openalex.org/I1331142282"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035788952","display_name":"Brett James Manley","orcid":"https://orcid.org/0000-0003-0212-7956","observed_orcids":["https://orcid.org/0000-0003-0212-7956"]},"institutions":[{"id":"https://openalex.org/I165779595","display_name":"The University of Melbourne","ror":"https://ror.org/01ej9dk98","country_code":"AU","type":"education","lineage":["https://openalex.org/I165779595"]},{"id":"https://openalex.org/I2800974353","display_name":"Mercy Hospital for Women","ror":"https://ror.org/01ch4qb51","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I2800974353"]},{"id":"https://openalex.org/I4210150290","display_name":"Murdoch Children's Research Institute","ror":"https://ror.org/048fyec77","country_code":"AU","type":"nonprofit","lineage":["https://openalex.org/I4210150290"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Brett J. Manley","raw_affiliation_strings":["Clinical Sciences, Murdoch Children's Research Institute, Melbourne, Australia","Department of Obstetrics, Gynaecology and Newborn Health, The University of Melbourne, Melbourne, Australia","Mercy Perinatal, Mercy Hospital for Women, Melbourne, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Sciences, Murdoch Children's Research Institute, Melbourne, Australia","institution_ids":["https://openalex.org/I4210150290"]},{"raw_affiliation_string":"Department of Obstetrics, Gynaecology and Newborn Health, The University of Melbourne, Melbourne, Australia","institution_ids":["https://openalex.org/I165779595"]},{"raw_affiliation_string":"Mercy Perinatal, Mercy Hospital for Women, Melbourne, Australia","institution_ids":["https://openalex.org/I2800974353"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036926038","display_name":"Cecilia L. Moore","orcid":"https://orcid.org/0000-0002-5438-6143","observed_orcids":["https://orcid.org/0000-0002-5438-6143"]},"institutions":[{"id":"https://openalex.org/I165779595","display_name":"The University of Melbourne","ror":"https://ror.org/01ej9dk98","country_code":"AU","type":"education","lineage":["https://openalex.org/I165779595"]},{"id":"https://openalex.org/I4210150290","display_name":"Murdoch Children's Research Institute","ror":"https://ror.org/048fyec77","country_code":"AU","type":"nonprofit","lineage":["https://openalex.org/I4210150290"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Cecilia Moore","raw_affiliation_strings":["Clinical Epidemiology and Biostatistics Unit, Murdoch Children's Research Institute, Melbourne, Australia","Department of Paediatrics, The University of Melbourne, Melbourne, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Epidemiology and Biostatistics Unit, Murdoch Children's Research Institute, Melbourne, Australia","institution_ids":["https://openalex.org/I4210150290"]},{"raw_affiliation_string":"Department of Paediatrics, The University of Melbourne, Melbourne, Australia","institution_ids":["https://openalex.org/I165779595"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015593879","display_name":"Jeanie L.Y. Cheong","orcid":"https://orcid.org/0000-0001-5901-0455","observed_orcids":["https://orcid.org/0000-0001-5901-0455"]},"institutions":[{"id":"https://openalex.org/I1331142282","display_name":"Royal Women's Hospital","ror":"https://ror.org/03grnna41","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I1331142282"]},{"id":"https://openalex.org/I165779595","display_name":"The University of Melbourne","ror":"https://ror.org/01ej9dk98","country_code":"AU","type":"education","lineage":["https://openalex.org/I165779595"]},{"id":"https://openalex.org/I4210150290","display_name":"Murdoch Children's Research Institute","ror":"https://ror.org/048fyec77","country_code":"AU","type":"nonprofit","lineage":["https://openalex.org/I4210150290"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Jeanie L. Y. Cheong","raw_affiliation_strings":["Clinical Sciences, Murdoch Children's Research Institute, Melbourne, Australia","Department of Obstetrics, Gynaecology and Newborn Health, The University of Melbourne, Melbourne, Australia","Department of Paediatrics, The University of Melbourne, Melbourne, Australia","Newborn Services and Newborn Research, Royal Women's Hospital, Melbourne, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Sciences, Murdoch Children's Research Institute, Melbourne, Australia","institution_ids":["https://openalex.org/I4210150290"]},{"raw_affiliation_string":"Department of Obstetrics, Gynaecology and Newborn Health, The University of Melbourne, Melbourne, Australia","institution_ids":["https://openalex.org/I165779595"]},{"raw_affiliation_string":"Department of Paediatrics, The University of Melbourne, Melbourne, Australia","institution_ids":["https://openalex.org/I165779595"]},{"raw_affiliation_string":"Newborn Services and Newborn Research, Royal Women's Hospital, Melbourne, Australia","institution_ids":["https://openalex.org/I1331142282"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046337825","display_name":"Ju Lee Oei","orcid":"https://orcid.org/0000-0002-7799-3771","observed_orcids":["https://orcid.org/0000-0002-7799-3771"]},"institutions":[{"id":"https://openalex.org/I129604602","display_name":"The University of Sydney","ror":"https://ror.org/0384j8v12","country_code":"AU","type":"education","lineage":["https://openalex.org/I129604602"]},{"id":"https://openalex.org/I2799851941","display_name":"Royal Hospital for Women","ror":"https://ror.org/021cxfs56","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I2799851941","https://openalex.org/I4210147382"]},{"id":"https://openalex.org/I31746571","display_name":"UNSW Sydney","ror":"https://ror.org/03r8z3t63","country_code":"AU","type":"education","lineage":["https://openalex.org/I31746571"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Ju Lee Oei","raw_affiliation_strings":["Department of Newborn Care, The Royal Hospital for Women, Randwick, NSW, Australia","Discipline of Paediatrics and Child Health, School of Clinical Medicine, University of New South Wales, Kensington, New South Wales, Australia","National Health and Research Medical Council Clinical Trials Centre, The University of Sydney, New South Wales, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Newborn Care, The Royal Hospital for Women, Randwick, NSW, Australia","institution_ids":["https://openalex.org/I2799851941"]},{"raw_affiliation_string":"Discipline of Paediatrics and Child Health, School of Clinical Medicine, University of New South Wales, Kensington, New South Wales, Australia","institution_ids":["https://openalex.org/I31746571"]},{"raw_affiliation_string":"National Health and Research Medical Council Clinical Trials Centre, The University of Sydney, New South Wales, Australia","institution_ids":["https://openalex.org/I129604602"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5122973572","display_name":"Li Huang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I165779595","display_name":"The University of Melbourne","ror":"https://ror.org/01ej9dk98","country_code":"AU","type":"education","lineage":["https://openalex.org/I165779595"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Li Huang","raw_affiliation_strings":["Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Australia","institution_ids":["https://openalex.org/I165779595"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041821959","display_name":"Peter Graham Davis","orcid":"https://orcid.org/0000-0001-6742-7314","observed_orcids":["https://orcid.org/0000-0001-6742-7314"]},"institutions":[{"id":"https://openalex.org/I1331142282","display_name":"Royal Women's Hospital","ror":"https://ror.org/03grnna41","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I1331142282"]},{"id":"https://openalex.org/I165779595","display_name":"The University of Melbourne","ror":"https://ror.org/01ej9dk98","country_code":"AU","type":"education","lineage":["https://openalex.org/I165779595"]},{"id":"https://openalex.org/I4210150290","display_name":"Murdoch Children's Research Institute","ror":"https://ror.org/048fyec77","country_code":"AU","type":"nonprofit","lineage":["https://openalex.org/I4210150290"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Peter G. Davis","raw_affiliation_strings":["Clinical Sciences, Murdoch Children's Research Institute, Melbourne, Australia","Department of Obstetrics, Gynaecology and Newborn Health, The University of Melbourne, Melbourne, Australia","Newborn Services and Newborn Research, Royal Women's Hospital, Melbourne, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Sciences, Murdoch Children's Research Institute, Melbourne, Australia","institution_ids":["https://openalex.org/I4210150290"]},{"raw_affiliation_string":"Department of Obstetrics, Gynaecology and Newborn Health, The University of Melbourne, Melbourne, Australia","institution_ids":["https://openalex.org/I165779595"]},{"raw_affiliation_string":"Newborn Services and Newborn Research, Royal Women's Hospital, Melbourne, Australia","institution_ids":["https://openalex.org/I1331142282"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054003098","display_name":"Louise S. Owen","orcid":"https://orcid.org/0000-0002-9490-6377","observed_orcids":["https://orcid.org/0000-0002-9490-6377"]},"institutions":[{"id":"https://openalex.org/I1331142282","display_name":"Royal Women's Hospital","ror":"https://ror.org/03grnna41","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I1331142282"]},{"id":"https://openalex.org/I165779595","display_name":"The University of Melbourne","ror":"https://ror.org/01ej9dk98","country_code":"AU","type":"education","lineage":["https://openalex.org/I165779595"]},{"id":"https://openalex.org/I4210150290","display_name":"Murdoch Children's Research Institute","ror":"https://ror.org/048fyec77","country_code":"AU","type":"nonprofit","lineage":["https://openalex.org/I4210150290"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Louise S. Owen","raw_affiliation_strings":["Clinical Sciences, Murdoch Children's Research Institute, Melbourne, Australia","Department of Obstetrics, Gynaecology and Newborn Health, The University of Melbourne, Melbourne, Australia","Newborn Services and Newborn Research, Royal Women's Hospital, Melbourne, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Sciences, Murdoch Children's Research Institute, Melbourne, Australia","institution_ids":["https://openalex.org/I4210150290"]},{"raw_affiliation_string":"Department of Obstetrics, Gynaecology and Newborn Health, The University of Melbourne, Melbourne, Australia","institution_ids":["https://openalex.org/I165779595"]},{"raw_affiliation_string":"Newborn Services and Newborn Research, Royal Women's Hospital, Melbourne, Australia","institution_ids":["https://openalex.org/I1331142282"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5056952810","display_name":"Anneke C Grobler","orcid":"https://orcid.org/0000-0002-7809-7688","observed_orcids":["https://orcid.org/0000-0002-7809-7688"]},"institutions":[{"id":"https://openalex.org/I165779595","display_name":"The University of Melbourne","ror":"https://ror.org/01ej9dk98","country_code":"AU","type":"education","lineage":["https://openalex.org/I165779595"]},{"id":"https://openalex.org/I4210150290","display_name":"Murdoch Children's Research Institute","ror":"https://ror.org/048fyec77","country_code":"AU","type":"nonprofit","lineage":["https://openalex.org/I4210150290"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Anneke Grobler","raw_affiliation_strings":["Clinical Epidemiology and Biostatistics Unit, Murdoch Children's Research Institute, Melbourne, Australia","Department of Paediatrics, The University of Melbourne, Melbourne, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Epidemiology and Biostatistics Unit, Murdoch Children's Research Institute, Melbourne, Australia","institution_ids":["https://openalex.org/I4210150290"]},{"raw_affiliation_string":"Department of Paediatrics, The University of Melbourne, Melbourne, Australia","institution_ids":["https://openalex.org/I165779595"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5022537165"],"corresponding_institution_ids":["https://openalex.org/I1331142282","https://openalex.org/I165779595","https://openalex.org/I4210150290"],"apc_list":{"value":2790,"currency":"USD","value_usd":2790},"apc_paid":{"value":2790,"currency":"USD","value_usd":2790},"fwci":8.9265,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.96126814,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":96,"max":97},"biblio":{"volume":"27","issue":"1","first_page":"121","last_page":"121"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10549","display_name":"Neonatal Respiratory Health Research","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10549","display_name":"Neonatal Respiratory Health Research","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11060","display_name":"Infant Development and Preterm Care","score":0.0010000000474974513,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10322","display_name":"Respiratory Support and Mechanisms","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/neonatal-respiratory-support","display_name":"neonatal respiratory support","score":0.7480000257492065},{"id":"https://openalex.org/keywords/delivery-room-resuscitation","display_name":"delivery room resuscitation","score":0.8029999732971191},{"id":"https://openalex.org/keywords/neonatal-oxygen-therapy","display_name":"neonatal oxygen therapy","score":0.47999998927116394},{"id":"https://openalex.org/keywords/sample-size-calculation","display_name":"sample size determination","score":0.6190000176429749},{"id":"https://openalex.org/keywords/statistical-analysis-plan","display_name":"statistical analysis plan","score":0.6259999871253967},{"id":"https://openalex.org/keywords/individual-patient-data","display_name":"individual patient data","score":0.6880000233650208},{"id":"https://openalex.org/keywords/risk-difference","display_name":"risk difference","score":0.43299999833106995},{"id":"https://openalex.org/keywords/waiver-of-informed-consent","display_name":"waiver of consent","score":0.4869999885559082},{"id":"https://openalex.org/keywords/neonatal-intensive-care-unit-admission","display_name":"neonatal intensive care admission","score":0.4569999873638153},{"id":"https://openalex.org/keywords/neonatal-mortality","display_name":"neonatal mortality","score":0.3610000014305115}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8953999876976013},{"id":"https://openalex.org/C2986587452","wikidata":"https://www.wikidata.org/wiki/Q938438","display_name":"Statistical analysis","level":2,"score":0.6168000102043152},{"id":"https://openalex.org/C87813604","wikidata":"https://www.wikidata.org/wiki/Q1242899","display_name":"Crossover study","level":4,"score":0.5821999907493591},{"id":"https://openalex.org/C535046627","wikidata":"https://www.wikidata.org/wiki/Q30612","display_name":"Clinical trial","level":2,"score":0.5372999906539917},{"id":"https://openalex.org/C194828623","wikidata":"https://www.wikidata.org/wiki/Q2861470","display_name":"Emergency medicine","level":1,"score":0.4823000133037567},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.46059998869895935},{"id":"https://openalex.org/C534529494","wikidata":"https://www.wikidata.org/wiki/Q7891","display_name":"Respiratory system","level":2,"score":0.4489000141620636},{"id":"https://openalex.org/C122507166","wikidata":"https://www.wikidata.org/wiki/Q628906","display_name":"Crossover","level":2,"score":0.3822999894618988},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.36309999227523804},{"id":"https://openalex.org/C2780334268","wikidata":"https://www.wikidata.org/wiki/Q3435476","display_name":"Nasal cannula","level":3,"score":0.36169999837875366},{"id":"https://openalex.org/C2779473830","wikidata":"https://www.wikidata.org/wiki/Q1540899","display_name":"MEDLINE","level":2,"score":0.34279999136924744},{"id":"https://openalex.org/C2994142871","wikidata":"https://www.wikidata.org/wiki/Q7873","display_name":"Oxygen delivery","level":3,"score":0.3319999873638153},{"id":"https://openalex.org/C3019138748","wikidata":"https://www.wikidata.org/wiki/Q1988216","display_name":"Supplemental oxygen","level":2,"score":0.3012999892234802},{"id":"https://openalex.org/C2780630273","wikidata":"https://www.wikidata.org/wiki/Q1988216","display_name":"Oxygen therapy","level":2,"score":0.29820001125335693},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.2946000099182129},{"id":"https://openalex.org/C168563851","wikidata":"https://www.wikidata.org/wiki/Q1436668","display_name":"Randomized controlled trial","level":2,"score":0.2689000070095062},{"id":"https://openalex.org/C2780409771","wikidata":"https://www.wikidata.org/wiki/Q2624498","display_name":"Life support","level":2,"score":0.2614000141620636},{"id":"https://openalex.org/C2779318504","wikidata":"https://www.wikidata.org/wiki/Q1438035","display_name":"Research design","level":2,"score":0.259799987077713},{"id":"https://openalex.org/C112299071","wikidata":"https://www.wikidata.org/wiki/Q835884","display_name":"Infant mortality","level":3,"score":0.2533000111579895}],"mesh":[{"descriptor_ui":"D001315","descriptor_name":"Australia","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001315","descriptor_name":"Australia","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001315","descriptor_name":"Australia","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001315","descriptor_name":"Australia","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001315","descriptor_name":"Australia","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001315","descriptor_name":"Australia","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001315","descriptor_name":"Australia","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001315","descriptor_name":"Australia","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003627","descriptor_name":"Data Interpretation, Statistical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003627","descriptor_name":"Data Interpretation, Statistical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003627","descriptor_name":"Data Interpretation, Statistical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003627","descriptor_name":"Data Interpretation, Statistical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003627","descriptor_name":"Data Interpretation, Statistical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003627","descriptor_name":"Data Interpretation, Statistical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003627","descriptor_name":"Data Interpretation, Statistical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003627","descriptor_name":"Data Interpretation, Statistical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003696","descriptor_name":"Delivery Rooms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D003696","descriptor_name":"Delivery Rooms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D003696","descriptor_name":"Delivery Rooms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D003696","descriptor_name":"Delivery Rooms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D003696","descriptor_name":"Delivery Rooms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D003696","descriptor_name":"Delivery Rooms","qualifier_ui":"Q000706","qualifier_name":"statistics & numerical data","is_major_topic":true},{"descriptor_ui":"D003696","descriptor_name":"Delivery Rooms","qualifier_ui":"Q000706","qualifier_name":"statistics & numerical data","is_major_topic":true},{"descriptor_ui":"D003696","descriptor_name":"Delivery Rooms","qualifier_ui":"Q000706","qualifier_name":"statistics & numerical data","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005865","descriptor_name":"Gestational Age","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005865","descriptor_name":"Gestational Age","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005865","descriptor_name":"Gestational Age","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005865","descriptor_name":"Gestational Age","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005865","descriptor_name":"Gestational Age","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005865","descriptor_name":"Gestational Age","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005865","descriptor_name":"Gestational Age","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005865","descriptor_name":"Gestational Age","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006771","descriptor_name":"Hospitals, Maternity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006771","descriptor_name":"Hospitals, Maternity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006771","descriptor_name":"Hospitals, Maternity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007231","descriptor_name":"Infant, Newborn","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007231","descriptor_name":"Infant, Newborn","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007231","descriptor_name":"Infant, Newborn","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007231","descriptor_name":"Infant, Newborn","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007231","descriptor_name":"Infant, Newborn","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007231","descriptor_name":"Infant, Newborn","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007231","descriptor_name":"Infant, Newborn","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007231","descriptor_name":"Infant, Newborn","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007234","descriptor_name":"Infant, Premature","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D007234","descriptor_name":"Infant, Premature","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D007234","descriptor_name":"Infant, Premature","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D007234","descriptor_name":"Infant, Premature","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D007234","descriptor_name":"Infant, Premature","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D007234","descriptor_name":"Infant, Premature","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D007234","descriptor_name":"Infant, Premature","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D007234","descriptor_name":"Infant, Premature","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D010100","descriptor_name":"Oxygen","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D010100","descriptor_name":"Oxygen","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D010100","descriptor_name":"Oxygen","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D010100","descriptor_name":"Oxygen","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D010100","descriptor_name":"Oxygen","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D010100","descriptor_name":"Oxygen","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D010100","descriptor_name":"Oxygen","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D010100","descriptor_name":"Oxygen","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D010102","descriptor_name":"Oxygen Inhalation Therapy","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D010102","descriptor_name":"Oxygen Inhalation Therapy","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D010102","descriptor_name":"Oxygen Inhalation Therapy","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D010102","descriptor_name":"Oxygen Inhalation Therapy","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D010102","descriptor_name":"Oxygen Inhalation Therapy","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D010102","descriptor_name":"Oxygen Inhalation Therapy","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D010102","descriptor_name":"Oxygen Inhalation Therapy","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D010102","descriptor_name":"Oxygen Inhalation Therapy","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D010102","descriptor_name":"Oxygen Inhalation Therapy","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D010102","descriptor_name":"Oxygen Inhalation Therapy","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D010102","descriptor_name":"Oxygen Inhalation Therapy","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D010102","descriptor_name":"Oxygen Inhalation Therapy","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D010102","descriptor_name":"Oxygen Inhalation Therapy","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D010102","descriptor_name":"Oxygen Inhalation Therapy","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D010102","descriptor_name":"Oxygen Inhalation Therapy","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D010102","descriptor_name":"Oxygen Inhalation Therapy","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012107","descriptor_name":"Research Design","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012107","descriptor_name":"Research Design","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012107","descriptor_name":"Research Design","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012127","descriptor_name":"Respiratory Distress Syndrome, Newborn","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D012127","descriptor_name":"Respiratory Distress Syndrome, Newborn","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D012127","descriptor_name":"Respiratory Distress Syndrome, Newborn","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D012127","descriptor_name":"Respiratory Distress Syndrome, Newborn","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D012127","descriptor_name":"Respiratory Distress Syndrome, Newborn","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D012127","descriptor_name":"Respiratory Distress Syndrome, Newborn","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D012127","descriptor_name":"Respiratory Distress Syndrome, Newborn","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D012127","descriptor_name":"Respiratory Distress Syndrome, Newborn","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D012127","descriptor_name":"Respiratory Distress Syndrome, Newborn","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015337","descriptor_name":"Multicenter Studies as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015337","descriptor_name":"Multicenter Studies as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015337","descriptor_name":"Multicenter Studies as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015337","descriptor_name":"Multicenter Studies as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015337","descriptor_name":"Multicenter Studies as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015337","descriptor_name":"Multicenter Studies as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015337","descriptor_name":"Multicenter Studies as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015337","descriptor_name":"Multicenter Studies as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016032","descriptor_name":"Randomized Controlled Trials as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016032","descriptor_name":"Randomized Controlled Trials as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016032","descriptor_name":"Randomized Controlled Trials as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016032","descriptor_name":"Randomized Controlled Trials as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016032","descriptor_name":"Randomized Controlled Trials as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016032","descriptor_name":"Randomized Controlled Trials as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016032","descriptor_name":"Randomized Controlled Trials as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016032","descriptor_name":"Randomized Controlled Trials as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018592","descriptor_name":"Cross-Over Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018592","descriptor_name":"Cross-Over Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018592","descriptor_name":"Cross-Over Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018592","descriptor_name":"Cross-Over Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018592","descriptor_name":"Cross-Over Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018592","descriptor_name":"Cross-Over Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018592","descriptor_name":"Cross-Over Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018592","descriptor_name":"Cross-Over Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1186/s13063-026-09437-5","doi":"https://doi.org/10.1186/s13063-026-09437-5","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s13063-026-09437-5","pdf_url":null,"source":{"id":"https://openalex.org/S109512841","display_name":"Trials","issn_l":"1745-6215","issn":["1745-6215"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Trials","raw_type":"journal-article"},{"id":"pmid:41535893","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/41535893","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Trials","raw_type":"Journal Article"},{"id":"pmh:oai:europepmc.org:11695950","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/12888391","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:41a329fe0a8d426e89ba9fa7f2507669","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/41a329fe0a8d426e89ba9fa7f2507669","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Trials, Vol 27, Iss 1 (2026)","raw_type":"article"},{"id":"pmh:oai:pubmedcentral.nih.gov:12888391","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12888391/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Trials","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1186/s13063-026-09437-5","doi":"https://doi.org/10.1186/s13063-026-09437-5","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s13063-026-09437-5","pdf_url":null,"source":{"id":"https://openalex.org/S109512841","display_name":"Trials","issn_l":"1745-6215","issn":["1745-6215"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Trials","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.98580002784729,"id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[{"display_name":"Good health and well-being","score":0.4740324020385742,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Study Protocol","id":"https://openalex.org/study-designs/study-protocol"}],"awards":[{"id":"https://openalex.org/G2532728505","display_name":"Improving Outcomes for Preterm Infants Through Randomised Clinical Trials","funder_award_id":"2016662","funder_id":"https://openalex.org/F4320334705","funder_display_name":"National Health and Medical Research Council"},{"id":"https://openalex.org/G5601580838","display_name":null,"funder_award_id":"1153176","funder_id":"https://openalex.org/F4320333776","funder_display_name":"Centre of Research Excellence in Newborn Medicine, Murdoch Children's Research Institute"},{"id":"https://openalex.org/G6471186926","display_name":"Lungs for life: a programme of clinical trials to improve respiratory outcomes for premature babies","funder_award_id":"2017734","funder_id":"https://openalex.org/F4320334705","funder_display_name":"National Health and Medical Research Council"}],"funders":[{"id":"https://openalex.org/F4320320974","display_name":"University of Melbourne","ror":"https://ror.org/01ej9dk98"},{"id":"https://openalex.org/F4320333776","display_name":"Centre of Research Excellence in Newborn Medicine, Murdoch Children's Research Institute","ror":null},{"id":"https://openalex.org/F4320334705","display_name":"National Health and Medical Research Council","ror":"https://ror.org/011kf5r70"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":5,"referenced_works":["https://openalex.org/W2093274439","https://openalex.org/W2102330235","https://openalex.org/W4320891754","https://openalex.org/W4406098344","https://openalex.org/W7117108525"],"related_works":[],"abstract_inverted_index":{"BACKGROUND:":[0],"Moderate-late":[1],"preterm":[2,16,71,101,155],"infants":[3,34,72,102,156,164,229,280],"born":[4,167],"at":[5,76,161,231,282],"32-35":[6,104],"completed":[7],"weeks'":[8,20,105,176],"gestation":[9,106,177],"constitute":[10],"a":[11,116,225,239,275,320,346,370,383],"large":[12],"proportion":[13],"of":[14,50,84,95,103,119,148,227,241,259,278,325],"all":[15],"births":[17],"(<":[18],"37":[19],"gestation),":[21],"yet":[22],"they":[23],"are":[24,59,165,185],"not":[25],"well":[26],"represented":[27],"in":[28,39,79,100,111,139,153,194,236,255,336,362],"the":[29,40,48,63,85,112,120,128,195,200,210,218,256,305,313,332,393,404],"newborn":[30],"resuscitation":[31],"literature.":[32],"Preterm":[33],"often":[35],"receive":[36,191],"respiratory":[37,74,109,124,159,192,214,309],"support":[38,75,110,125,160,193,215,310],"delivery":[41,113,129,196,219,314],"room,":[42,114,315],"and":[43,97,150,189,271,334,349,382],"recommendations":[44],"exist":[45],"to":[46,89,172,250,266,391,403],"guide":[47],"use":[49],"supplemental":[51],"oxygen":[52,67,93,146],"when":[53,311],"providing":[54],"this":[55,326],"support.":[56],"However,":[57],"there":[58],"minimal":[60],"data":[61],"regarding":[62],"best":[64],"initial":[65,91,144],"supplementary":[66,92,145],"concentration":[68],"for":[69,122,212,399],"moderate-late":[70,154],"requiring":[73],"birth,":[77],"resulting":[78],"practice":[80],"variation.":[81],"The":[82,206,221,301,323,340,407],"aim":[83],"AIROPLANE":[86],"trial":[87,138,222],"is":[88,209,299,307],"compare":[90],"concentrations":[94,147],"30%":[96,149],"21%":[98,151],"(air)":[99,152],"who":[107,157,184,190],"require":[108,158],"with":[115,268,289,369,377],"primary":[117,207,257,302,408],"outcome":[118,208,258,327],"need":[121,211],"ongoing":[123,213],"upon":[126,216],"leaving":[127,217,312],"room.":[130,220],"METHODS:":[131],"A":[132,359],"prospective,":[133],"unblinded,":[134],"multicenter,":[135],"cluster-randomized,":[136],"crossover":[137,291],"Australian":[140,422],"maternity":[141],"hospitals":[142],"comparing":[143],"birth.":[162,205],"Eligible":[163],"those":[166],"from":[168,230,264,281],"32":[169],"+":[170,174],"0":[171],"35":[173],"6":[175],"without":[178],"major":[179],"cardiorespiratory":[180],"or":[181],"craniofacial":[182],"anomalies,":[183],"receiving":[186,308],"active":[187],"care,":[188],"room":[197],"commencing":[198],"within":[199,395],"first":[201],"three":[202],"minutes":[203],"after":[204],"will":[223,316,328,342,366,410],"recruit":[224],"minimum":[226,276],"1,200":[228],"least":[232,283],"20":[233,284],"study":[234],"sites":[235,286],"Australia":[237],"using":[238,345,354,386],"waiver":[240],"consent":[242],"process.":[243],"STATISTICAL":[244],"ANALYSIS":[245],"PLAN:":[246],"To":[247],"be":[248,317,329,343,367,411],"able":[249],"demonstrate":[251],"an":[252,378,387],"absolute":[253],"reduction":[254,262],"8%":[260],"(relative":[261],"16%),":[263],"51":[265],"43%,":[267],"80%":[269],"power":[270],"5%":[272],"alpha":[273],"level,":[274],"sample":[277,361],"1200":[279],"participating":[285],"(20":[287],"clusters)":[288],"one":[290],"halfway":[292],"through":[293],"each":[294,337,363,396],"site's":[295],"total":[296],"enrolment":[297],"period":[298,365,401],"required.":[300],"outcome,":[303],"whether":[304],"infant":[306],"analyzed":[318],"as":[319,331],"binary":[321],"outcome.":[322],"incidence":[324],"summarized":[330],"number":[333],"percentage":[335],"treatment":[338,364,400],"arm.":[339],"treatments":[341],"compared":[344],"risk":[347],"difference":[348],"95%":[350],"confidence":[351],"interval":[352],"(CI)":[353],"individual":[355],"participant":[356],"level":[357],"data.":[358],"cross-sectional":[360],"modelled":[368],"mixed":[371],"effects":[372],"generalized":[373],"linear":[374],"model":[375,392],"(GLM)":[376],"identity":[379],"link":[380],"function":[381],"binomial":[384],"distribution":[385],"exchangeable":[388],"correlation":[389,394],"structure":[390],"cluster,":[397],"adjusted":[398],"due":[402],"cross-over":[405],"nature.":[406],"analysis":[409],"by":[412],"intention-to-treat.":[413],"TRIAL":[414],"REGISTRATION:":[415],"ACTRN12621001267842.":[416],"Registered":[417],"on":[418],"20th":[419],"September":[420],"2021.":[421],"New":[423],"Zealand":[424],"Clinical":[425],"Trials":[426],"Registry":[427],"(":[428],"https://www.anzctr.org.au":[429],").":[430]},"counts_by_year":[{"year":2026,"cited_by_count":2}],"updated_date":"2026-10-14T16:39:01.820549","created_date":"2026-01-14T00:00:00"}