{"id":"https://openalex.org/W7123364346","doi":"https://doi.org/10.1097/crd.0000000000001174","title":"Microplastics: A Modifiable Cardiac Risk Factor","display_name":"Microplastics: A Modifiable Cardiac Risk Factor","publication_year":2026,"publication_date":"2026-01-13","ids":{"openalex":"https://openalex.org/W7123364346","doi":"https://doi.org/10.1097/crd.0000000000001174","pmid":"https://pubmed.ncbi.nlm.nih.gov/41527182"},"language":"en","primary_location":{"id":"doi:10.1097/crd.0000000000001174","doi":"https://doi.org/10.1097/crd.0000000000001174","is_oa":true,"landing_page_url":"https://doi.org/10.1097/crd.0000000000001174","pdf_url":null,"source":{"id":"https://openalex.org/S173369630","display_name":"Cardiology in Review","issn_l":"1061-5377","issn":["1061-5377","1538-4683"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","medline","norway-1"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cardiology in Review","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1097/crd.0000000000001174","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5122879953","display_name":"Michael Kaiser","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1341523491","display_name":"NewYork\u2013Presbyterian Brooklyn Methodist Hospital","ror":"https://ror.org/04929s478","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1340179700","https://openalex.org/I1341523491"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Michael Kaiser","raw_affiliation_strings":["Department of Medicine, New York Presbyterian Brooklyn Methodist Hospital, Brooklyn, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, New York Presbyterian Brooklyn Methodist Hospital, Brooklyn, NY","institution_ids":["https://openalex.org/I1341523491"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5122886988","display_name":"Elena Tran","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1341523491","display_name":"NewYork\u2013Presbyterian Brooklyn Methodist Hospital","ror":"https://ror.org/04929s478","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1340179700","https://openalex.org/I1341523491"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Elena Tran","raw_affiliation_strings":["Department of Medicine, New York Presbyterian Brooklyn Methodist Hospital, Brooklyn, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, New York Presbyterian Brooklyn Methodist Hospital, Brooklyn, NY","institution_ids":["https://openalex.org/I1341523491"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103956647","display_name":"Manish A. Parikh","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1341523491","display_name":"NewYork\u2013Presbyterian Brooklyn Methodist Hospital","ror":"https://ror.org/04929s478","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1340179700","https://openalex.org/I1341523491"]},{"id":"https://openalex.org/I4387153466","display_name":"Weill Cornell Medicine","ror":"https://ror.org/02r109517","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295","https://openalex.org/I4387153466"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Manish A. Parikh","raw_affiliation_strings":["Department of Medicine, New York Presbyterian Brooklyn Methodist Hospital, Brooklyn, NY","Weill Department of Medicine, Weill Cornell Medicine, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, New York Presbyterian Brooklyn Methodist Hospital, Brooklyn, NY","institution_ids":["https://openalex.org/I1341523491"]},{"raw_affiliation_string":"Weill Department of Medicine, Weill Cornell Medicine, New York, NY","institution_ids":["https://openalex.org/I4387153466"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081321042","display_name":"Gioia Turitto","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1341523491","display_name":"NewYork\u2013Presbyterian Brooklyn Methodist Hospital","ror":"https://ror.org/04929s478","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1340179700","https://openalex.org/I1341523491"]},{"id":"https://openalex.org/I4387153466","display_name":"Weill Cornell Medicine","ror":"https://ror.org/02r109517","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295","https://openalex.org/I4387153466"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Gioia Turitto","raw_affiliation_strings":["Department of Medicine, New York Presbyterian Brooklyn Methodist Hospital, Brooklyn, NY","Weill Department of Medicine, Weill Cornell Medicine, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, New York Presbyterian Brooklyn Methodist Hospital, Brooklyn, NY","institution_ids":["https://openalex.org/I1341523491"]},{"raw_affiliation_string":"Weill Department of Medicine, Weill Cornell Medicine, New York, NY","institution_ids":["https://openalex.org/I4387153466"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020544805","display_name":"William H. Frishman","orcid":"https://orcid.org/0000-0002-2458-4480","observed_orcids":["https://orcid.org/0000-0002-2458-4480"]},"institutions":[{"id":"https://openalex.org/I181190671","display_name":"New York Medical College","ror":"https://ror.org/03dkvy735","country_code":"US","type":"education","lineage":["https://openalex.org/I181190671"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"William H. Frishman","raw_affiliation_strings":["Department of Medicine, New York Medical College, Valhalla, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, New York Medical College, Valhalla, NY","institution_ids":["https://openalex.org/I181190671"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5056430981","display_name":"Stephen J. Peterson","orcid":"https://orcid.org/0000-0002-6847-3969","observed_orcids":["https://orcid.org/0000-0002-6847-3969"]},"institutions":[{"id":"https://openalex.org/I1341523491","display_name":"NewYork\u2013Presbyterian Brooklyn Methodist Hospital","ror":"https://ror.org/04929s478","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1340179700","https://openalex.org/I1341523491"]},{"id":"https://openalex.org/I4387153466","display_name":"Weill Cornell Medicine","ror":"https://ror.org/02r109517","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295","https://openalex.org/I4387153466"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Stephen J. Peterson","raw_affiliation_strings":["Department of Medicine, New York Presbyterian Brooklyn Methodist Hospital, Brooklyn, NY","Weill Department of Medicine, Weill Cornell Medicine, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, New York Presbyterian Brooklyn Methodist Hospital, Brooklyn, NY","institution_ids":["https://openalex.org/I1341523491"]},{"raw_affiliation_string":"Weill Department of Medicine, Weill Cornell Medicine, New York, NY","institution_ids":["https://openalex.org/I4387153466"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5056430981","https://openalex.org/A5081321042","https://openalex.org/A5103956647","https://openalex.org/A5122879953","https://openalex.org/A5122886988"],"corresponding_institution_ids":["https://openalex.org/I1341523491","https://openalex.org/I4387153466"],"apc_list":null,"apc_paid":null,"fwci":9.2745,"has_fulltext":false,"cited_by_count":5,"citation_normalized_percentile":{"value":0.97780167,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":98,"max":99},"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10753","display_name":"Microplastics and Plastic Pollution","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2310","display_name":"Pollution"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10753","display_name":"Microplastics and Plastic Pollution","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2310","display_name":"Pollution"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10190","display_name":"Air Quality and Health Impacts","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T13522","display_name":"Cardiovascular Health and Risk Factors","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/microplastics","display_name":"microplastics","score":1.0},{"id":"https://openalex.org/keywords/nanoplastics","display_name":"nanoplastics","score":0.9980000257492065},{"id":"https://openalex.org/keywords/cardiovascular-disease","display_name":"cardiovascular disease","score":0.9700000286102295},{"id":"https://openalex.org/keywords/cardiovascular-risk-factors","display_name":"cardiovascular risk factors","score":0.8889999985694885},{"id":"https://openalex.org/keywords/oxidative-stress","display_name":"oxidative stress","score":0.8960000276565552},{"id":"https://openalex.org/keywords/mitochondrial-dysfunction","display_name":"mitochondrial dysfunction","score":0.9950000047683716},{"id":"https://openalex.org/keywords/endothelial-dysfunction","display_name":"endothelial dysfunction","score":1.0},{"id":"https://openalex.org/keywords/inflammation","display_name":"inflammation","score":0.9470000267028809},{"id":"https://openalex.org/keywords/thrombosis","display_name":"thrombosis","score":0.9990000128746033},{"id":"https://openalex.org/keywords/dyslipidemia","display_name":"dyslipidemia","score":1.0},{"id":"https://openalex.org/keywords/cardiotoxicity","display_name":"cardiotoxicity","score":0.9980000257492065},{"id":"https://openalex.org/keywords/coronary-artery-plaque","display_name":"coronary plaque","score":0.8500000238418579},{"id":"https://openalex.org/keywords/carotid-plaque","display_name":"carotid plaque","score":0.9909999966621399},{"id":"https://openalex.org/keywords/myocardial-infarction","display_name":"myocardial infarction","score":0.9879999756813049},{"id":"https://openalex.org/keywords/stroke","display_name":"stroke","score":0.7089999914169312},{"id":"https://openalex.org/keywords/modifiable-risk-factors","display_name":"modifiable risk factors","score":0.8370000123977661}],"concepts":[{"id":"https://openalex.org/C2780401329","wikidata":"https://www.wikidata.org/wiki/Q6839919","display_name":"Microplastics","level":2,"score":0.9502999782562256},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9473000168800354},{"id":"https://openalex.org/C50440223","wikidata":"https://www.wikidata.org/wiki/Q1475848","display_name":"Risk factor","level":2,"score":0.5874999761581421},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.5339000225067139},{"id":"https://openalex.org/C3018906752","wikidata":"https://www.wikidata.org/wiki/Q844935","display_name":"Coronary heart disease","level":2,"score":0.47200000286102295},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4693000018596649},{"id":"https://openalex.org/C72563966","wikidata":"https://www.wikidata.org/wiki/Q1303415","display_name":"Cohort","level":2,"score":0.414900004863739},{"id":"https://openalex.org/C12174686","wikidata":"https://www.wikidata.org/wiki/Q1058438","display_name":"Risk assessment","level":2,"score":0.37310001254081726},{"id":"https://openalex.org/C2909478654","wikidata":"https://www.wikidata.org/wiki/Q844935","display_name":"Atherosclerotic cardiovascular disease","level":3,"score":0.3386000096797943},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.33629998564720154},{"id":"https://openalex.org/C201903717","wikidata":"https://www.wikidata.org/wiki/Q1778788","display_name":"Cohort study","level":2,"score":0.32519999146461487},{"id":"https://openalex.org/C2778213512","wikidata":"https://www.wikidata.org/wiki/Q844935","display_name":"Coronary artery disease","level":2,"score":0.3221000134944916},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.28690001368522644},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.26429998874664307}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1097/crd.0000000000001174","doi":"https://doi.org/10.1097/crd.0000000000001174","is_oa":true,"landing_page_url":"https://doi.org/10.1097/crd.0000000000001174","pdf_url":null,"source":{"id":"https://openalex.org/S173369630","display_name":"Cardiology in Review","issn_l":"1061-5377","issn":["1061-5377","1538-4683"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","medline","norway-1"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cardiology in Review","raw_type":"journal-article"},{"id":"pmid:41527182","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/41527182","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cardiology in review","raw_type":"Journal Article"},{"id":"pmh:oai:ecommons.cornell.edu:1813/124338","doi":null,"is_oa":true,"landing_page_url":"https://ecommons.cornell.edu/items/2102a44b-98c6-49dd-a196-0ff0e6cdedb5/request-a-copy?bitstream=ff20f64d-7559-4872-8da4-feb3f6a9aa22","pdf_url":null,"source":{"id":"https://openalex.org/S4306400757","display_name":"eCommons (Cornell University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I205783295","host_organization_name":"Cornell University","host_organization_lineage":["https://openalex.org/I205783295"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article"}],"best_oa_location":{"id":"doi:10.1097/crd.0000000000001174","doi":"https://doi.org/10.1097/crd.0000000000001174","is_oa":true,"landing_page_url":"https://doi.org/10.1097/crd.0000000000001174","pdf_url":null,"source":{"id":"https://openalex.org/S173369630","display_name":"Cardiology in Review","issn_l":"1061-5377","issn":["1061-5377","1538-4683"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","medline","norway-1"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cardiology in Review","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9763000011444092,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[{"score":0.8405584096908569,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":32,"referenced_works":["https://openalex.org/W2037496050","https://openalex.org/W2737217596","https://openalex.org/W2762862468","https://openalex.org/W2948574679","https://openalex.org/W2977747666","https://openalex.org/W3036656245","https://openalex.org/W3043184549","https://openalex.org/W3087333805","https://openalex.org/W3109968655","https://openalex.org/W3113178943","https://openalex.org/W3157788918","https://openalex.org/W3196209586","https://openalex.org/W4211134725","https://openalex.org/W4220655782","https://openalex.org/W4220900610","https://openalex.org/W4283758418","https://openalex.org/W4310017057","https://openalex.org/W4313529905","https://openalex.org/W4317435121","https://openalex.org/W4384156484","https://openalex.org/W4386475472","https://openalex.org/W4392520497","https://openalex.org/W4402326418","https://openalex.org/W4403306046","https://openalex.org/W4403463687","https://openalex.org/W4405586439","https://openalex.org/W4406618430","https://openalex.org/W4409370256","https://openalex.org/W4409563244","https://openalex.org/W4411428023","https://openalex.org/W4415656766","https://openalex.org/W4416627326"],"related_works":[],"abstract_inverted_index":{"Globally,":[0],"cardiovascular":[1,42,120],"disease":[2],"is":[3],"the":[4,29,36,105],"most":[5],"prevalent":[6],"cause":[7],"of":[8,28,39,95,109],"death,":[9,100],"and":[10,34,49,61,66],"there":[11],"are":[12,18,89],"other":[13],"risk":[14,94,118],"factors":[15],"involved":[16],"that":[17,47,88],"not":[19],"captured":[20],"through":[21],"traditional":[22],"means.":[23],"We":[24],"present":[25],"a":[26,91,102,115],"review":[27],"literature":[30],"on":[31],"microplastic":[32],"exposure":[33],"discuss":[35],"clinical":[37,75],"implications":[38],"microplastics":[40,65,84],"for":[41,119],"disease.":[43,121],"Experimental":[44],"studies":[45],"show":[46],"micro-":[48],"nanoplastics":[50,67],"induce":[51],"oxidative":[52],"stress,":[53],"mitochondrial":[54],"dysfunction,":[55,57],"endothelial":[56],"inflammation,":[58],"thrombosis,":[59],"dyslipidemia,":[60],"direct":[62],"cardiotoxicity.":[63],"These":[64],"have":[68,77],"been":[69],"identified":[70],"in":[71,81,85,101,111],"coronary":[72],"plaque.":[73],"Emerging":[74],"data":[76],"recently":[78],"reported":[79],"evidence":[80],"patients":[82],"having":[83],"carotid":[86],"plaques":[87],"at":[90],"4.5-fold":[92],"increased":[93],"myocardial":[96],"infarction,":[97],"stroke,":[98],"or":[99],"cohort":[103],"from":[104],"New":[106],"England":[107],"Journal":[108],"Medicine":[110],"2024.":[112],"Microplastics":[113],"remain":[114],"potential":[116],"modifiable":[117]},"counts_by_year":[{"year":2026,"cited_by_count":5}],"updated_date":"2026-10-07T09:51:55.459714","created_date":"2026-01-14T00:00:00"}
