{"id":"https://openalex.org/W7123338692","doi":"https://doi.org/10.70976/j.1008-0805.szgygy-2025-2312","title":"Study on optimized processing technology of Herba Cistanche Tubulosa Decoction Pieces\uff08\u7ba1\u82b1\u8089\u82c1\u84c9\u996e\u7247\uff09 and its mechanism in regulating macrophage anti-oxidative stress","display_name":"Study on optimized processing technology of Herba Cistanche Tubulosa Decoction Pieces\uff08\u7ba1\u82b1\u8089\u82c1\u84c9\u996e\u7247\uff09 and its mechanism in regulating macrophage anti-oxidative stress","publication_year":2025,"publication_date":"2025-12-01","ids":{"openalex":"https://openalex.org/W7123338692","doi":"https://doi.org/10.70976/j.1008-0805.szgygy-2025-2312"},"language":"en","primary_location":{"id":"doi:10.70976/j.1008-0805.szgygy-2025-2312","doi":"https://doi.org/10.70976/j.1008-0805.szgygy-2025-2312","is_oa":true,"landing_page_url":"https://doi.org/10.70976/j.1008-0805.szgygy-2025-2312","pdf_url":"https://www.tcmjc.com/download/pdf?id=EFD31084E03D4093B6C98073287020BB","source":{"id":"https://openalex.org/S2764554180","display_name":"Lishizhen Medicine and Materia Medica Research","issn_l":"1008-0805","issn":["1008-0805"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4361727481","host_organization_name":"Shizhen Journal of Traditional Chinese Medicine","host_organization_lineage":["https://openalex.org/P4361727481"],"host_organization_lineage_names":["Shizhen Journal of Traditional Chinese Medicine"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Lishizhen medicine and materia medica research","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://www.tcmjc.com/download/pdf?id=EFD31084E03D4093B6C98073287020BB","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5122876058","display_name":"Salamaiti AIDIRESI","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Salamaiti AIDIRESI","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5122871143","display_name":"Gulifeire YILIHAMU","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Gulifeire YILIHAMU","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5122848524","display_name":"Atawula TIEMUER","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Atawula TIEMUER","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5094082917","display_name":"Aizaiti Keremu","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Aizaiti KEREMU","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.6159948,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"36","issue":"23","first_page":"4491","last_page":"4499"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11709","display_name":"Traditional Chinese Medicine Analysis","score":0.9911999702453613,"subfield":{"id":"https://openalex.org/subfields/2707","display_name":"Complementary and alternative medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11709","display_name":"Traditional Chinese Medicine Analysis","score":0.9911999702453613,"subfield":{"id":"https://openalex.org/subfields/2707","display_name":"Complementary and alternative medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11613","display_name":"Phytochemistry and Biological Activities","score":0.0052999998442828655,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T14521","display_name":"Medicinal Plant Research","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cistanche-tubulosa","display_name":"Cistanche tubulosa","score":0.8629999756813049},{"id":"https://openalex.org/keywords/traditional-chinese-medicine-processing","display_name":"traditional Chinese medicine processing","score":0.6169999837875366},{"id":"https://openalex.org/keywords/antioxidant-activity","display_name":"antioxidant activity","score":0.7229999899864197},{"id":"https://openalex.org/keywords/oxidative-stress","display_name":"oxidative stress","score":0.9660000205039978},{"id":"https://openalex.org/keywords/anti-inflammatory-activity","display_name":"anti-inflammatory activity","score":0.8500000238418579},{"id":"https://openalex.org/keywords/raw-264-7-macrophages","display_name":"RAW 264.7 macrophages","score":0.847000002861023},{"id":"https://openalex.org/keywords/lipid-peroxidation","display_name":"lipid peroxidation","score":0.8700000047683716},{"id":"https://openalex.org/keywords/cytokines","display_name":"cytokines","score":0.5979999899864197},{"id":"https://openalex.org/keywords/process-optimization","display_name":"process optimization","score":0.3889999985694885}],"concepts":[{"id":"https://openalex.org/C190409667","wikidata":"https://www.wikidata.org/wiki/Q1136912","display_name":"Decoction","level":2,"score":0.8136000037193298},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.7609000205993652},{"id":"https://openalex.org/C2779244956","wikidata":"https://www.wikidata.org/wiki/Q184204","display_name":"Macrophage","level":3,"score":0.5619999766349792},{"id":"https://openalex.org/C89611455","wikidata":"https://www.wikidata.org/wiki/Q6804646","display_name":"Mechanism (biology)","level":2,"score":0.552299976348877},{"id":"https://openalex.org/C556039675","wikidata":"https://www.wikidata.org/wiki/Q771035","display_name":"Traditional medicine","level":1,"score":0.4697999954223633},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.4156000018119812},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.36000001430511475},{"id":"https://openalex.org/C2776120743","wikidata":"https://www.wikidata.org/wiki/Q3271540","display_name":"Mechanism of action","level":3,"score":0.34540000557899475},{"id":"https://openalex.org/C21036866","wikidata":"https://www.wikidata.org/wiki/Q181767","display_name":"Stress (linguistics)","level":2,"score":0.33709999918937683},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.26460000872612},{"id":"https://openalex.org/C2777066959","wikidata":"https://www.wikidata.org/wiki/Q869711","display_name":"Cricetulus","level":4,"score":0.25690001249313354}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.70976/j.1008-0805.szgygy-2025-2312","doi":"https://doi.org/10.70976/j.1008-0805.szgygy-2025-2312","is_oa":true,"landing_page_url":"https://doi.org/10.70976/j.1008-0805.szgygy-2025-2312","pdf_url":"https://www.tcmjc.com/download/pdf?id=EFD31084E03D4093B6C98073287020BB","source":{"id":"https://openalex.org/S2764554180","display_name":"Lishizhen Medicine and Materia Medica Research","issn_l":"1008-0805","issn":["1008-0805"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4361727481","host_organization_name":"Shizhen Journal of Traditional Chinese Medicine","host_organization_lineage":["https://openalex.org/P4361727481"],"host_organization_lineage_names":["Shizhen Journal of Traditional Chinese Medicine"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Lishizhen medicine and materia medica research","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.70976/j.1008-0805.szgygy-2025-2312","doi":"https://doi.org/10.70976/j.1008-0805.szgygy-2025-2312","is_oa":true,"landing_page_url":"https://doi.org/10.70976/j.1008-0805.szgygy-2025-2312","pdf_url":"https://www.tcmjc.com/download/pdf?id=EFD31084E03D4093B6C98073287020BB","source":{"id":"https://openalex.org/S2764554180","display_name":"Lishizhen Medicine and Materia Medica Research","issn_l":"1008-0805","issn":["1008-0805"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4361727481","host_organization_name":"Shizhen Journal of Traditional Chinese Medicine","host_organization_lineage":["https://openalex.org/P4361727481"],"host_organization_lineage_names":["Shizhen Journal of Traditional Chinese Medicine"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Lishizhen medicine and materia medica research","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.5683000087738037}],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7123338692.pdf","grobid_xml":"https://content.openalex.org/works/W7123338692.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":[],"abstract_inverted_index":{"\u76ee\u7684":[0],"\u4f18\u5316\u7ba1\u82b1\u8089\u82c1\u84c9\u996e\u7247\u70ae\u5236\u5de5\u827a\uff0c\u63d0\u9ad8\u6bdb\u854a\u82b1\u7cd6\u82f7\u548c\u677e\u679c\u83ca\u82f7\u7684\u542b\u91cf\uff0c\u9a8c\u8bc1\u5176\u996e\u7247\u7684\u6297\u6c27\u5316\u5e94\u6fc0\u6d3b\u6027\u5e76\u63a2\u7a76\u5176\u4f5c\u7528\u4fe1\u53f7\u901a\u8def\u3002":[1],"\u65b9\u6cd5":[2],"\u8fd0\u7528\u73b0\u4ee3\u5316\u70ae\u5236\u624b\u6bb5\uff0c\u6bdb\u854a\u82b1\u7cd6\u82f7\u548c\u677e\u679c\u83ca\u82f7\u542b\u91cf\u4e3a\u8bc4\u4ef7\u6307\u6807\uff0c\u5728\u5355\u56e0\u7d20\u8bd5\u9a8c\u57fa\u7840\u4e0a\uff0c\u4ee5\u996e\u7247\u539a\u5ea6\u3001\u84b8\u5904\u7406\u65f6\u95f4\u548c\u70d8\u5e72\u6e29\u5ea6\u4e3a\u5f71\u54cd\u56e0\u7d20\uff0c\u8fdb\u884cBox-Behnken\u54cd\u5e94\u9762\u4f18\u5316\u70ae\u5236\u5de5\u827a\u6761\u4ef6\u3002\u540c\u65f6\u5efa\u7acb\u8102\u591a\u7cd6\u8bf1\u5bfc\u7684RAW264.7\u7ec6\u80de\u8102\u8d28\u8fc7\u6c27\u5316\u548c\u708e\u75c7\u635f\u4f24\u6a21\u578b\uff0c\u6765\u63a2\u7a76\u6700\u4f73\u70ae\u5236\u996e\u7247\u5728\u7ec6\u80de\u5c42\u9762\u7684\u6297\u6c27\u5316\u5e94\u6fc0\u4f5c\u7528\u673a\u5236\u3002":[3],"\u7ed3\u679c":[4],"\u7ba1\u82b1\u8089\u82c1\u84c9\u996e\u7247\u70ae\u5236\u6700\u4f73\u5de5\u827a\u6761\u4ef6\u4e3a\u996e\u7247\u539a\u5ea60.6":[5],"cm\uff0c\u84b8\u5904\u7406\u65f6\u95f46":[6],"min\uff0c\u70d8\u5e72\u6e29\u5ea657":[7],"\u2103\u65f6\uff0c\u5f97\u5230\u6bdb\u854a\u82b1\u7cd6\u82f7\u548c\u677e\u679c\u83ca\u82f7\u7684\u63d0\u53d6\u7387\u4e3a7.25":[8],"%\u548c31.62":[9],"%\u3002\u7ec6\u80de\u5b9e\u9a8c\u7ed3\u679c\u8bc1\u5b9e\u4e86\u7ba1\u82b1\u8089\u82c1\u84c9\u70ae\u5236\u996e\u7247\u5728\u6025\u6027\u708e\u75c7\u65f6\uff0c\u80fd\u964d\u4f4e\u4e00\u6c27\u5316\u6c2e\uff08NO\uff09\u548c\u4e19\u4e8c\u919b\uff08MDA\uff09\u542b\u91cf\uff0c\u6709\u6548\u63d0\u9ad8\u8d85\u6c27\u5316\u7269\u6b67\u5316\u9176\uff08SOD\uff09\u3001\u4e73\u9178\u8131\u6c22\u9176\uff08LDH\uff09\u3001\u8fc7\u6c27\u5316\u6c22\u9176\uff08CAT\uff09\u3001\u8c37\u80f1\u7518\u80bd\uff08GSH\uff09\u7b49\u6297\u6c27\u5316\u548c\u6c27\u5316\u5e94\u6fc0\u76f8\u5173\u9176\u6d3b\u6027\uff0c\u8fd8\u80fd\u663e\u8457\u964d\u4f4eIL-1\u03b2\u3001IL-6\u3001TNF-\u03b1\u4fc3\u708e\u7ec6\u80de\u56e0\u5b50\u7684\u6c34\u5e73\u3002\u6b64\u5916\uff0c\u86cb\u767d\u5370\u8ff9\u5b9e\u9a8c\u7ed3\u679c\u8868\u660e\uff0c\u7ba1\u82b1\u8089\u82c1\u84c9\u70ae\u5236\u996e\u7247\u8fd8\u80fd\u901a\u8fc7\u6291\u5236p38/AKT/JNK/NF-\u03baB\u4fe1\u53f7\u901a\u8def\uff0c\u964d\u4f4e\u6c27\u5316\u5e94\u6fc0\u53cd\u5e94\u3002":[10],"\u7ed3\u8bba":[11],"\u7814\u7a76\u7684\u70ae\u5236\u65b9\u6cd5\u80fd\u589e\u52a0\u6bdb\u854a\u82b1\u7cd6\u82f7\u548c\u677e\u679c\u83ca\u82f7\u7684\u63d0\u53d6\u7387\uff0c\u63d0\u9ad8\u5176\u7ec6\u80de\u6297\u6c27\u5316\u6297\u708e\u6d3b\u6027\uff0c\u6709\u6548\u6291\u5236\u6c27\u5316\u5e94\u6fc0\u53cd\u5e94\u3002":[12]},"counts_by_year":[],"updated_date":"2026-08-23T07:36:19.812096","created_date":"2026-01-14T00:00:00"}