{"id":"https://openalex.org/W7122633481","doi":"https://doi.org/10.1016/s0025-6196(26)01482-5","title":"Midodrine","display_name":"Midodrine","publication_year":1981,"publication_date":"1981-07-01","ids":{"openalex":"https://openalex.org/W7122633481","doi":"https://doi.org/10.1016/s0025-6196(26)01482-5","mag":"54583788","pmid":"https://pubmed.ncbi.nlm.nih.gov/6166817"},"language":"en","primary_location":{"id":"doi:10.1016/s0025-6196(26)01482-5","doi":"https://doi.org/10.1016/s0025-6196(26)01482-5","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s0025-6196(26)01482-5","pdf_url":null,"source":{"id":"https://openalex.org/S58241369","display_name":"Mayo Clinic Proceedings","issn_l":"0025-6196","issn":["0025-6196","1942-5546"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Mayo Clinic Proceedings","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://doi.org/10.1016/s0025-6196(26)01482-5","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5068545646","display_name":"ALEXANDER SCHIRGER","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Alexander Schirger","raw_affiliation_strings":["Division of Cardiovascular Diseases and Internal Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiovascular Diseases and Internal Medicine","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028146354","display_name":"Sheldon G. Sheps","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Sheldon C. Sheps","raw_affiliation_strings":["Division of Cardiovascular Diseases and Internal Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiovascular Diseases and Internal Medicine","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069376910","display_name":"Juergen E. Thomas","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Juergen E. Thomas","raw_affiliation_strings":["Department ol Neurology"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department ol Neurology","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5058330394","display_name":"Robert D. Fealey","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Robert D. Fealey","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3900,"currency":"USD","value_usd":3900},"apc_paid":null,"fwci":2.4685,"has_fulltext":false,"cited_by_count":80,"citation_normalized_percentile":{"value":0.89298512,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":96},"biblio":{"volume":"56","issue":"7","first_page":"429","last_page":"433"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11950","display_name":"Cardiovascular Syncope and Autonomic Disorders","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11950","display_name":"Cardiovascular Syncope and Autonomic Disorders","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10745","display_name":"Heart Rate Variability and Autonomic Control","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10144","display_name":"Blood Pressure and Hypertension Studies","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/midodrine","display_name":"midodrine","score":1.0},{"id":"https://openalex.org/keywords/idiopathic-orthostatic-hypotension","display_name":"idiopathic orthostatic hypotension","score":0.9520000219345093},{"id":"https://openalex.org/keywords/shy-drager-syndrome","display_name":"Shy-Drager syndrome","score":0.9850000143051147},{"id":"https://openalex.org/keywords/multiple-system-atrophy","display_name":"multiple system atrophy","score":0.8799999952316284},{"id":"https://openalex.org/keywords/alpha-adrenergic-agonists","display_name":"alpha-adrenergic agonists","score":0.8849999904632568},{"id":"https://openalex.org/keywords/blood-pressure","display_name":"blood pressure","score":0.7020000219345093},{"id":"https://openalex.org/keywords/supine-hypertension","display_name":"supine hypertension","score":0.9169999957084656},{"id":"https://openalex.org/keywords/metoprolol","display_name":"metoprolol","score":0.902999997138977},{"id":"https://openalex.org/keywords/drug-therapy","display_name":"pharmacotherapy","score":0.3160000145435333}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9879000186920166},{"id":"https://openalex.org/C2780081974","wikidata":"https://www.wikidata.org/wiki/Q415051","display_name":"Midodrine","level":4,"score":0.8859000205993652},{"id":"https://openalex.org/C125567185","wikidata":"https://www.wikidata.org/wiki/Q3267428","display_name":"Supine position","level":2,"score":0.7218999862670898},{"id":"https://openalex.org/C73787029","wikidata":"https://www.wikidata.org/wiki/Q7104929","display_name":"Orthostatic vital signs","level":3,"score":0.6973000168800354},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.6154999732971191},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.5087000131607056},{"id":"https://openalex.org/C57900726","wikidata":"https://www.wikidata.org/wiki/Q492905","display_name":"Diastole","level":3,"score":0.428600013256073},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.35120001435279846},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.33090001344680786},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.31610000133514404},{"id":"https://openalex.org/C178853913","wikidata":"https://www.wikidata.org/wiki/Q1642137","display_name":"Hemodynamics","level":2,"score":0.2930999994277954},{"id":"https://openalex.org/C2777372248","wikidata":"https://www.wikidata.org/wiki/Q171064","display_name":"Autonomic nervous system","level":4,"score":0.2842000126838684},{"id":"https://openalex.org/C2994510025","wikidata":"https://www.wikidata.org/wiki/Q179661","display_name":"Medical therapy","level":2,"score":0.2535000145435333}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001342","descriptor_name":"Autonomic Nervous System Diseases","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D001794","descriptor_name":"Blood Pressure","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004983","descriptor_name":"Ethanolamines","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007024","descriptor_name":"Hypotension, Orthostatic","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008879","descriptor_name":"Midodrine","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D011187","descriptor_name":"Posture","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012791","descriptor_name":"Shy-Drager Syndrome","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1016/s0025-6196(26)01482-5","doi":"https://doi.org/10.1016/s0025-6196(26)01482-5","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s0025-6196(26)01482-5","pdf_url":null,"source":{"id":"https://openalex.org/S58241369","display_name":"Mayo Clinic Proceedings","issn_l":"0025-6196","issn":["0025-6196","1942-5546"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Mayo Clinic Proceedings","raw_type":"journal-article"},{"id":"pmid:6166817","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/6166817","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Mayo Clinic proceedings","raw_type":"Case Reports"},{"id":"mag:54583788","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/6166817","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":{"id":"doi:10.1016/s0025-6196(26)01482-5","doi":"https://doi.org/10.1016/s0025-6196(26)01482-5","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s0025-6196(26)01482-5","pdf_url":null,"source":{"id":"https://openalex.org/S58241369","display_name":"Mayo Clinic Proceedings","issn_l":"0025-6196","issn":["0025-6196","1942-5546"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Mayo Clinic Proceedings","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9922999739646912,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":7,"referenced_works":["https://openalex.org/W1569523303","https://openalex.org/W1594857824","https://openalex.org/W1967300763","https://openalex.org/W1974980169","https://openalex.org/W2008185903","https://openalex.org/W2111666318","https://openalex.org/W2341219139"],"related_works":["https://openalex.org/W54583788","https://openalex.org/W164936153","https://openalex.org/W2048764982","https://openalex.org/W4255068392","https://openalex.org/W2029445782","https://openalex.org/W2364948067","https://openalex.org/W4294549596","https://openalex.org/W2471473990","https://openalex.org/W2086953184","https://openalex.org/W2176017769"],"abstract_inverted_index":null,"counts_by_year":[{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":3},{"year":2016,"cited_by_count":2},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":2}],"updated_date":"2026-11-05T12:25:35.769452","created_date":"2026-01-13T00:00:00"}