{"id":"https://openalex.org/W7122365985","doi":"https://doi.org/10.1016/j.mimet.2026.107392","title":"Exploring the potential of postbiotic Limosilactobacillus fermentum as a novel therapeutic agent for Candida albicans","display_name":"Exploring the potential of postbiotic Limosilactobacillus fermentum as a novel therapeutic agent for Candida albicans","publication_year":2026,"publication_date":"2026-01-12","ids":{"openalex":"https://openalex.org/W7122365985","doi":"https://doi.org/10.1016/j.mimet.2026.107392","pmid":"https://pubmed.ncbi.nlm.nih.gov/41534796"},"language":"en","primary_location":{"id":"doi:10.1016/j.mimet.2026.107392","doi":"https://doi.org/10.1016/j.mimet.2026.107392","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.mimet.2026.107392","pdf_url":null,"source":{"id":"https://openalex.org/S24124513","display_name":"Journal of Microbiological Methods","issn_l":"0167-7012","issn":["0167-7012","1872-8359"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Microbiological Methods","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5054447592","display_name":"Guhanraj Radhamanalan","orcid":"https://orcid.org/0000-0003-4146-8008","observed_orcids":["https://orcid.org/0000-0003-4146-8008"]},"institutions":[{"id":"https://openalex.org/I85461943","display_name":"Saveetha University","ror":"https://ror.org/0034me914","country_code":"IN","type":"education","lineage":["https://openalex.org/I85461943"]}],"countries":["IN"],"is_corresponding":true,"raw_author_name":"Guhanraj Radhamanalan","raw_affiliation_strings":["Department of Microbiology, White lab, Saveetha Dental College, Chennai 600077, Tamil Nadu, India. Electronic address: drrguhanraj@gmail.com"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology, White lab, Saveetha Dental College, Chennai 600077, Tamil Nadu, India. Electronic address: drrguhanraj@gmail.com","institution_ids":["https://openalex.org/I85461943"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110984486","display_name":"Sowmiya Soundararajan","orcid":"https://orcid.org/0000-0001-8663-1089","observed_orcids":["https://orcid.org/0000-0001-8663-1089"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Sowmiya Soundararajan","raw_affiliation_strings":["Vivekananda College of Arts and Sciences for Women, Tiruchengode, Namakkal 637205, Tamil Nadu, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Vivekananda College of Arts and Sciences for Women, Tiruchengode, Namakkal 637205, Tamil Nadu, India","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041438163","display_name":"Ragothaman Prathiviraj","orcid":"https://orcid.org/0000-0002-4747-1374","observed_orcids":["https://orcid.org/0000-0002-4747-1374"]},"institutions":[{"id":"https://openalex.org/I4388891759","display_name":"Rajagiri College of Social Sciences (Autonomous)","ror":"https://ror.org/00tqx3b24","country_code":"IN","type":"education","lineage":["https://openalex.org/I4388891759"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Ragothaman Prathiviraj","raw_affiliation_strings":["Division of Bioinformatics and Systems Biology, Department of Biosciences, Rajagiri College of Social Sciences (Autonomous), Rajagiri P.O., Kalamassery, Kochi 683104, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Bioinformatics and Systems Biology, Department of Biosciences, Rajagiri College of Social Sciences (Autonomous), Rajagiri P.O., Kalamassery, Kochi 683104, India","institution_ids":["https://openalex.org/I4388891759"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5147462132","display_name":"Dhanasekaran Dharumadurai","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4076070","display_name":"Bharathidasan University","ror":"https://ror.org/02w7vnb60","country_code":"IN","type":"education","lineage":["https://openalex.org/I4076070"]}],"countries":["IN"],"is_corresponding":true,"raw_author_name":"Dhanasekaran Dharumadurai","raw_affiliation_strings":["Department of Microbiology, Bharathidasan University, Tiruchirappalli 620024, Tamil Nadu, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology, Bharathidasan University, Tiruchirappalli 620024, Tamil Nadu, India","institution_ids":["https://openalex.org/I4076070"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5006881263","display_name":"Ponnusamy Manogaran Gopinath","orcid":"https://orcid.org/0000-0001-7512-0961","observed_orcids":["https://orcid.org/0000-0001-7512-0961"]},"institutions":[{"id":"https://openalex.org/I83737708","display_name":"REVA University","ror":"https://ror.org/03gtcxd54","country_code":"IN","type":"education","lineage":["https://openalex.org/I83737708"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Gopinath Ponnusamy Manogaran","raw_affiliation_strings":["Department of Biotechnology, School of Applied Sciences, REVA University, Bangalore 560064, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biotechnology, School of Applied Sciences, REVA University, Bangalore 560064, India","institution_ids":["https://openalex.org/I83737708"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5054447592","https://openalex.org/A5147462132"],"corresponding_institution_ids":["https://openalex.org/I4076070","https://openalex.org/I85461943"],"apc_list":{"value":3120,"currency":"USD","value_usd":3120},"apc_paid":null,"fwci":15.931,"has_fulltext":false,"cited_by_count":7,"citation_normalized_percentile":{"value":0.99150434,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":98,"max":99},"biblio":{"volume":"241","issue":null,"first_page":"107392","last_page":"107392"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10141","display_name":"Probiotics and Fermented Foods","score":0.8759999871253967,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10141","display_name":"Probiotics and Fermented Foods","score":0.8759999871253967,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10150","display_name":"Antifungal resistance and susceptibility","score":0.06260000169277191,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10257","display_name":"Oral microbiology and periodontitis research","score":0.019300000742077827,"subfield":{"id":"https://openalex.org/subfields/3506","display_name":"Periodontics"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/postbiotics","display_name":"postbiotics","score":0.8799999952316284},{"id":"https://openalex.org/keywords/limosilactobacillus-fermentum","display_name":"Lactobacillus fermentum","score":0.9879999756813049},{"id":"https://openalex.org/keywords/candida-albicans","display_name":"Candida albicans","score":0.9929999709129333},{"id":"https://openalex.org/keywords/candida-tropicalis","display_name":"Candida tropicalis","score":1.0},{"id":"https://openalex.org/keywords/dental-caries","display_name":"dental caries","score":0.9819999933242798},{"id":"https://openalex.org/keywords/antifungal-resistance","display_name":"antifungal resistance","score":0.9589999914169312},{"id":"https://openalex.org/keywords/fluconazole-resistance","display_name":"fluconazole resistance","score":0.9070000052452087},{"id":"https://openalex.org/keywords/ketoconazole-resistance","display_name":"ketoconazole resistance","score":0.9909999966621399},{"id":"https://openalex.org/keywords/candida-biofilms","display_name":"Candida biofilms","score":0.7680000066757202},{"id":"https://openalex.org/keywords/antifungal-activity","display_name":"antifungal activity","score":0.7369999885559082},{"id":"https://openalex.org/keywords/dental-prophylaxis","display_name":"dental prophylaxis","score":0.7490000128746033}],"concepts":[{"id":"https://openalex.org/C2780917455","wikidata":"https://www.wikidata.org/wiki/Q310443","display_name":"Candida albicans","level":2,"score":0.8310999870300293},{"id":"https://openalex.org/C2781064554","wikidata":"https://www.wikidata.org/wiki/Q407883","display_name":"Ketoconazole","level":3,"score":0.786899983882904},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.7692999839782715},{"id":"https://openalex.org/C2775835631","wikidata":"https://www.wikidata.org/wiki/Q143138","display_name":"Candida tropicalis","level":3,"score":0.6783999800682068},{"id":"https://openalex.org/C2780651595","wikidata":"https://www.wikidata.org/wiki/Q411478","display_name":"Fluconazole","level":3,"score":0.6668000221252441},{"id":"https://openalex.org/C2776503186","wikidata":"https://www.wikidata.org/wiki/Q2134039","display_name":"Lactobacillus fermentum","level":5,"score":0.5720000267028809},{"id":"https://openalex.org/C2777229883","wikidata":"https://www.wikidata.org/wiki/Q410534","display_name":"Miconazole","level":3,"score":0.5496000051498413},{"id":"https://openalex.org/C145081991","wikidata":"https://www.wikidata.org/wiki/Q2576388","display_name":"Corpus albicans","level":3,"score":0.5212000012397766},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5149000287055969},{"id":"https://openalex.org/C2779222958","wikidata":"https://www.wikidata.org/wiki/Q45422","display_name":"Yeast","level":2,"score":0.421099990606308},{"id":"https://openalex.org/C58123911","wikidata":"https://www.wikidata.org/wiki/Q467410","display_name":"Biofilm","level":3,"score":0.4205999970436096},{"id":"https://openalex.org/C2779629538","wikidata":"https://www.wikidata.org/wiki/Q412223","display_name":"Amphotericin B","level":3,"score":0.35370001196861267},{"id":"https://openalex.org/C2777071850","wikidata":"https://www.wikidata.org/wiki/Q411229","display_name":"Itraconazole","level":3,"score":0.3506999909877777},{"id":"https://openalex.org/C2779548794","wikidata":"https://www.wikidata.org/wiki/Q578726","display_name":"Antifungal","level":2,"score":0.350600004196167},{"id":"https://openalex.org/C2780255968","wikidata":"https://www.wikidata.org/wiki/Q1816730","display_name":"Probiotic","level":3,"score":0.3463999927043915},{"id":"https://openalex.org/C2986629439","wikidata":"https://www.wikidata.org/wiki/Q9635","display_name":"Oral cavity","level":2,"score":0.3278999924659729},{"id":"https://openalex.org/C501593827","wikidata":"https://www.wikidata.org/wiki/Q12187","display_name":"Antibiotics","level":2,"score":0.2867000102996826},{"id":"https://openalex.org/C90080823","wikidata":"https://www.wikidata.org/wiki/Q193129","display_name":"Hypha","level":2,"score":0.2784999907016754},{"id":"https://openalex.org/C2780670043","wikidata":"https://www.wikidata.org/wiki/Q139137","display_name":"Candida glabrata","level":3,"score":0.2644999921321869},{"id":"https://openalex.org/C114851261","wikidata":"https://www.wikidata.org/wiki/Q12147416","display_name":"Drug resistance","level":2,"score":0.2533000111579895},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2529999911785126}],"mesh":[{"descriptor_ui":"D000898","descriptor_name":"Antibiosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000935","descriptor_name":"Antifungal Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D002176","descriptor_name":"Candida albicans","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D002176","descriptor_name":"Candida albicans","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D002176","descriptor_name":"Candida albicans","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":true},{"descriptor_ui":"D002176","descriptor_name":"Candida albicans","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":true},{"descriptor_ui":"D002176","descriptor_name":"Candida albicans","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D003731","descriptor_name":"Dental Caries","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D003731","descriptor_name":"Dental Caries","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007194","descriptor_name":"India","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008826","descriptor_name":"Microbial Sensitivity Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012337","descriptor_name":"RNA, Ribosomal, 18S","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D015725","descriptor_name":"Fluconazole","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D018441","descriptor_name":"Biofilms","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D018441","descriptor_name":"Biofilms","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":false},{"descriptor_ui":"D019936","descriptor_name":"Probiotics","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D019936","descriptor_name":"Probiotics","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D025141","descriptor_name":"Drug Resistance, Fungal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D041022","descriptor_name":"Candida tropicalis","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D041022","descriptor_name":"Candida tropicalis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D041022","descriptor_name":"Candida tropicalis","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":false},{"descriptor_ui":"D052197","descriptor_name":"Limosilactobacillus fermentum","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.mimet.2026.107392","doi":"https://doi.org/10.1016/j.mimet.2026.107392","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.mimet.2026.107392","pdf_url":null,"source":{"id":"https://openalex.org/S24124513","display_name":"Journal of Microbiological Methods","issn_l":"0167-7012","issn":["0167-7012","1872-8359"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Microbiological Methods","raw_type":"journal-article"},{"id":"pmid:41534796","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/41534796","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of microbiological methods","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9763000011444092,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G2080683105","display_name":null,"funder_award_id":"2.0)/2018","funder_id":"https://openalex.org/F4320337076","funder_display_name":"Rashtriya Uchchatar Shiksha Abhiyan"}],"funders":[{"id":"https://openalex.org/F4320337076","display_name":"Rashtriya Uchchatar Shiksha Abhiyan","ror":null},{"id":"https://openalex.org/F4724395936","display_name":"Bharathidasan University","ror":"https://ror.org/02w7vnb60"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":64,"referenced_works":["https://openalex.org/W2042934913","https://openalex.org/W2085682801","https://openalex.org/W2091822734","https://openalex.org/W2238187854","https://openalex.org/W2761413688","https://openalex.org/W2762801383","https://openalex.org/W2792771323","https://openalex.org/W2799524357","https://openalex.org/W2810053911","https://openalex.org/W2817750257","https://openalex.org/W2883703760","https://openalex.org/W2898290575","https://openalex.org/W2908975219","https://openalex.org/W3023959358","https://openalex.org/W3028343005","https://openalex.org/W3063488753","https://openalex.org/W3088424400","https://openalex.org/W3093410264","https://openalex.org/W3096062053","https://openalex.org/W3116921899","https://openalex.org/W3126241748","https://openalex.org/W3135251593","https://openalex.org/W3154572760","https://openalex.org/W3160794980","https://openalex.org/W3165127368","https://openalex.org/W3165425323","https://openalex.org/W3165450467","https://openalex.org/W3177042505","https://openalex.org/W3181856238","https://openalex.org/W3203666995","https://openalex.org/W4214679124","https://openalex.org/W4220805189","https://openalex.org/W4221122872","https://openalex.org/W4224227163","https://openalex.org/W4281382004","https://openalex.org/W4285138630","https://openalex.org/W4292548579","https://openalex.org/W4303644892","https://openalex.org/W4308393142","https://openalex.org/W4319158213","https://openalex.org/W4323567712","https://openalex.org/W4327589613","https://openalex.org/W4363674701","https://openalex.org/W4376645941","https://openalex.org/W4377011025","https://openalex.org/W4382937189","https://openalex.org/W4388833028","https://openalex.org/W4390344994","https://openalex.org/W4400225450","https://openalex.org/W4400654843","https://openalex.org/W4402790917","https://openalex.org/W4404657326","https://openalex.org/W4405198525","https://openalex.org/W4406376898","https://openalex.org/W4407118663","https://openalex.org/W4407263168","https://openalex.org/W4407554476","https://openalex.org/W4408219033","https://openalex.org/W4408571531","https://openalex.org/W4410516981","https://openalex.org/W4410540965","https://openalex.org/W4413109028","https://openalex.org/W4413255724","https://openalex.org/W4413915282"],"related_works":["https://openalex.org/W4390344994","https://openalex.org/W7140174206","https://openalex.org/W4319158213","https://openalex.org/W7018002539","https://openalex.org/W3116921899","https://openalex.org/W4404051250","https://openalex.org/W2034139820","https://openalex.org/W7218114781","https://openalex.org/W4412785512","https://openalex.org/W3158068884"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":7}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2026-01-13T00:00:00"}