{"id":"https://openalex.org/W7120596445","doi":null,"title":"Assessment of social and anxiety-like behaviors, and the corticosterone response in male and female adolescent rats submitted to maternal deprivation in the neonatal period","display_name":"Assessment of social and anxiety-like behaviors, and the corticosterone response in male and female adolescent rats submitted to maternal deprivation in the neonatal period","publication_year":2017,"publication_date":"2017-03-31","ids":{"openalex":"https://openalex.org/W7120596445"},"language":"pt","primary_location":{"id":"pmh:oai:repositorio.unifesp.br:11600/50415","doi":null,"is_oa":true,"landing_page_url":"https://sucupira.capes.gov.br/sucupira/public/consultas/coleta/trabalhoConclusao/viewTrabalhoConclusao.jsf?popup=true&id_trabalho=5077817","pdf_url":"http://repositorio.unifesp.br/handle/11600/50415","source":{"id":"https://openalex.org/S4306402641","display_name":"LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Cient\u00edficas)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4383465926","host_organization_name":"LA Referencia","host_organization_lineage":["https://openalex.org/I4383465926"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"instacron:UNIFESP","raw_type":"info:eu-repo/semantics/masterThesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://repositorio.unifesp.br/handle/11600/50415","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5050391689","display_name":"Viviane C. Ceschim","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I88273585","display_name":"Universidade Federal de S\u00e3o Paulo","ror":"https://ror.org/02k5swt12","country_code":"BR","type":"education","lineage":["https://openalex.org/I88273585"]}],"countries":["BR"],"is_corresponding":true,"raw_author_name":"Ceschim, Viviane Cortes [UNIFESP]","raw_affiliation_strings":["UNIFESP -Universidade Federal de S\u00e3o Paulo xi xii"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"UNIFESP -Universidade Federal de S\u00e3o Paulo xi xii","institution_ids":["https://openalex.org/I88273585"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5050391689"],"corresponding_institution_ids":["https://openalex.org/I88273585"],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10529","display_name":"Stress Responses and Cortisol","score":0.9740999937057495,"subfield":{"id":"https://openalex.org/subfields/2802","display_name":"Behavioral Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10529","display_name":"Stress Responses and Cortisol","score":0.9740999937057495,"subfield":{"id":"https://openalex.org/subfields/2802","display_name":"Behavioral Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11541","display_name":"Neuroendocrine regulation and behavior","score":0.010400000028312206,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10426","display_name":"Child Abuse and Trauma","score":0.007300000172108412,"subfield":{"id":"https://openalex.org/subfields/3203","display_name":"Clinical Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/maternal-deprivation","display_name":"maternal deprivation","score":0.9800000190734863},{"id":"https://openalex.org/keywords/childhood-adversity","display_name":"childhood adversity","score":0.9419999718666077},{"id":"https://openalex.org/keywords/anxiety-like-behavior","display_name":"anxiety-like behavior","score":0.9340000152587891},{"id":"https://openalex.org/keywords/social-behavior","display_name":"social behavior","score":0.718999981880188},{"id":"https://openalex.org/keywords/corticosterone","display_name":"corticosterone","score":0.7990000247955322},{"id":"https://openalex.org/keywords/adolescent-rats","display_name":"adolescent rats","score":0.6869999766349792},{"id":"https://openalex.org/keywords/sex-differences","display_name":"sex differences","score":0.9179999828338623},{"id":"https://openalex.org/keywords/social-interest","display_name":"social interest","score":0.49000000953674316},{"id":"https://openalex.org/keywords/open-field-locomotion","display_name":"open field locomotion","score":0.597000002861023},{"id":"https://openalex.org/keywords/stress-related-psychiatric-disorders","display_name":"stress-related psychiatric disorders","score":0.5049999952316284},{"id":"https://openalex.org/keywords/ontogeny","display_name":"ontogeny","score":0.35100001096725464},{"id":"https://openalex.org/keywords/maternal-care","display_name":"maternal care","score":0.3930000066757202},{"id":"https://openalex.org/keywords/nest-temperature","display_name":"nest temperature","score":0.3089999854564667}],"concepts":[{"id":"https://openalex.org/C123202247","wikidata":"https://www.wikidata.org/wiki/Q2322778","display_name":"Maternal deprivation","level":2,"score":0.7799000144004822},{"id":"https://openalex.org/C2780352252","wikidata":"https://www.wikidata.org/wiki/Q422543","display_name":"Corticosterone","level":3,"score":0.7479000091552734},{"id":"https://openalex.org/C2780655333","wikidata":"https://www.wikidata.org/wiki/Q333203","display_name":"Weaning","level":2,"score":0.7469000220298767},{"id":"https://openalex.org/C13543017","wikidata":"https://www.wikidata.org/wiki/Q4430231","display_name":"Social deprivation","level":2,"score":0.6589000225067139},{"id":"https://openalex.org/C2779429622","wikidata":"https://www.wikidata.org/wiki/Q1780867","display_name":"Litter","level":2,"score":0.6136000156402588},{"id":"https://openalex.org/C42407357","wikidata":"https://www.wikidata.org/wiki/Q521","display_name":"Physiology","level":1,"score":0.4657999873161316},{"id":"https://openalex.org/C558461103","wikidata":"https://www.wikidata.org/wiki/Q154430","display_name":"Anxiety","level":2,"score":0.42399999499320984},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.4228000044822693},{"id":"https://openalex.org/C152630561","wikidata":"https://www.wikidata.org/wiki/Q6997750","display_name":"Nest (protein structural motif)","level":2,"score":0.4171999990940094},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.39899998903274536},{"id":"https://openalex.org/C138496976","wikidata":"https://www.wikidata.org/wiki/Q175002","display_name":"Developmental psychology","level":1,"score":0.3944999873638153},{"id":"https://openalex.org/C160272327","wikidata":"https://www.wikidata.org/wiki/Q841007","display_name":"Cage","level":2,"score":0.3215000033378601},{"id":"https://openalex.org/C149923435","wikidata":"https://www.wikidata.org/wiki/Q37732","display_name":"Demography","level":1,"score":0.3154999911785126},{"id":"https://openalex.org/C2776659692","wikidata":"https://www.wikidata.org/wiki/Q719426","display_name":"Lactation","level":3,"score":0.31130000948905945},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.3100000023841858},{"id":"https://openalex.org/C2781291010","wikidata":"https://www.wikidata.org/wiki/Q178580","display_name":"Period (music)","level":2,"score":0.2962999939918518},{"id":"https://openalex.org/C2780841215","wikidata":"https://www.wikidata.org/wiki/Q422549","display_name":"Glucocorticoid","level":2,"score":0.29109999537467957},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.28600001335144043},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2773999869823456},{"id":"https://openalex.org/C207886595","wikidata":"https://www.wikidata.org/wiki/Q1456138","display_name":"Pathological","level":2,"score":0.2761000096797943},{"id":"https://openalex.org/C2778117688","wikidata":"https://www.wikidata.org/wiki/Q264024","display_name":"Animal model","level":2,"score":0.26739999651908875},{"id":"https://openalex.org/C99476002","wikidata":"https://www.wikidata.org/wiki/Q42297","display_name":"Analysis of variance","level":2,"score":0.2623000144958496}],"mesh":[],"locations_count":1,"locations":[{"id":"pmh:oai:repositorio.unifesp.br:11600/50415","doi":null,"is_oa":true,"landing_page_url":"https://sucupira.capes.gov.br/sucupira/public/consultas/coleta/trabalhoConclusao/viewTrabalhoConclusao.jsf?popup=true&id_trabalho=5077817","pdf_url":"http://repositorio.unifesp.br/handle/11600/50415","source":{"id":"https://openalex.org/S4306402641","display_name":"LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Cient\u00edficas)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4383465926","host_organization_name":"LA Referencia","host_organization_lineage":["https://openalex.org/I4383465926"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"instacron:UNIFESP","raw_type":"info:eu-repo/semantics/masterThesis"}],"best_oa_location":{"id":"pmh:oai:repositorio.unifesp.br:11600/50415","doi":null,"is_oa":true,"landing_page_url":"https://sucupira.capes.gov.br/sucupira/public/consultas/coleta/trabalhoConclusao/viewTrabalhoConclusao.jsf?popup=true&id_trabalho=5077817","pdf_url":"http://repositorio.unifesp.br/handle/11600/50415","source":{"id":"https://openalex.org/S4306402641","display_name":"LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Cient\u00edficas)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4383465926","host_organization_name":"LA Referencia","host_organization_lineage":["https://openalex.org/I4383465926"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"instacron:UNIFESP","raw_type":"info:eu-repo/semantics/masterThesis"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9537000060081482}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7120596445.pdf","grobid_xml":"https://content.openalex.org/works/W7120596445.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2883199333","https://openalex.org/W3126077591","https://openalex.org/W2027568008","https://openalex.org/W2128836119","https://openalex.org/W2046865704","https://openalex.org/W4205259909","https://openalex.org/W2955909879","https://openalex.org/W7120531209","https://openalex.org/W2555294804","https://openalex.org/W7120611333"],"abstract_inverted_index":{"Introduction:":[0],"Early":[1],"life":[2],"adversity":[3],"represents":[4],"major":[5],"risk":[6],"factors":[7],"for":[8,70,215,270,284,287,409,491],"stress-related":[9],"psychiatric":[10],"disorders,":[11],"such":[12],"as":[13,362],"anxiety":[14],"and":[15,79,98,108,135,149,159,183,232,251,255,290,295,303,349,360,378,381,394,423,456,478,494,501],"depression.":[16],"These":[17,512],"pathological":[18],"conditions":[19],"are":[20],"characterized":[21],"by":[22,28,416],"impairment":[23],"of":[24,30,37,42,51,57,63,67,73,168,221,292,331,338,356,384,434,450,498],"social":[25,31,96,103,326,401,471,482],"behavior,":[26],"reflected":[27],"avoidance":[29],"interaction.":[32],"Among":[33],"the":[34,55,61,68,71,77,85,93,102,144,166,181,212,219,222,225,276,281,297,301,309,315,319,325,336,339,350,357,363,367,371,376,379,382,400,406,429,432,435,448,451,460,466,499],"numerous":[35],"models":[36],"childhood":[38],"adversity,":[39],"24":[40,216,312],"h":[41,313],"maternal":[43,52,169,516],"deprivation":[44,170,223,517],"can":[45],"be":[46],"considered":[47],"a":[48,200,353,485,519],"transient":[49],"loss":[50],"care,":[53],"displaying":[54],"advantage":[56],"pointing":[58],"out":[59],"to":[60,101,155,204,206,210,263,268,280,289,324,420],"importance":[62],"age":[64,361],"and,":[65],"consequently,":[66],"ontogenesis,":[69],"outcomes":[72],"this":[74],"manipulation":[75],"on":[76,120,127,162,199,245,465,522],"brain":[78],"behavior":[80,89,294,317,524],"developmental":[81],"trajectory.":[82],"Objectives:":[83],"In":[84],"present":[86],"study,":[87],"anxiety-like":[88,293,316,523],"was":[90,153,197,306,347,388,438,489],"evaluated":[91],"in":[92,106,185,208,266,300,335,418,443,447,459,531],"open":[94,282,340,452],"field,":[95,283,341],"interest":[97],"corticosterone":[99,272,425,504],"response":[100,487],"investigation":[104,327,402,472],"test,":[105,328,403],"male":[107],"female":[109],"adolescent":[110],"rats":[111],"that":[112,488,515],"were":[113,141,178,227,261,278,322,392,413,507],"either":[114],"non-manipulated":[115],"\u2013":[116],"control":[117],"(CTL),":[118],"maternally-deprived":[119],"postnatal":[121],"day":[122,167],"(PND)":[123],"3":[124,172],"(DEP3)":[125],"or":[126,173,404],"PND":[128,163,174,246],"11":[129],"(DEP11),":[130],"tested":[131],"between":[132],"PNDs":[133,249],"40":[134,250],"45.":[136],"Methods:":[137],"Twenty":[138],"four":[139,157,160],"litters":[140,177,226],"distributed":[142],"throughout":[143],"three":[145],"groups,":[146],"CTL,":[147],"DEP3":[148,441],"DEP11.":[150],"Each":[151],"litter":[152,260],"standardized":[154],"contain":[156],"males":[158,254],"females":[161,257,442,458],"1.":[164],"On":[165,308],"(PND":[171],"11),":[175],"whole":[176],"removed":[179],"from":[180,239,258],"maternity-cage":[182],"placed":[184,198],"another":[186],"cage":[187,196,241],"containing":[188,342],"clean":[189],"sawdust,":[190],"mixed":[191],"with":[192,229,476,533],"nest":[193,213],"material.":[194],"This":[195],"heating":[201],"pad":[202],"adjusted":[203],"30":[205],"33oC,":[207],"order":[209,267,419],"mimic":[211],"temperature,":[214],"h.":[217],"At":[218],"end":[220],"period,":[224],"reunited":[228],"their":[230],"dams":[231],"remained":[233],"together,":[234],"without":[235],"any":[236],"disruption,":[237],"except":[238],"routine":[240],"cleaning,":[242],"until":[243],"weaning":[244],"21.":[247],"Between":[248],"45,":[252],"two":[253,256,343],"each":[259],"assigned":[262],"non-tested":[264,410],"animals,":[265],"provide":[269,421],"basal":[271,422],"plasma":[273,426,505],"levels,":[274],"whereas":[275],"remainder":[277],"exposed":[279,323],"10":[285,368],"min,":[286],"habituation":[288],"assessment":[291],"during":[296],"session":[298,391],"locomotion":[299],"central":[302],"peripheral":[304],"segments":[305],"counted.":[307],"next":[310],"day,":[311],"after":[314,399],"assessment,":[318],"same":[320,358,461],"animals":[321,412],"which":[329],"consisted":[330],"placing":[332],"them,":[333],"individually,":[334],"center":[337,449],"metal":[344],"baskets:":[345],"one":[346],"empty":[348],"other":[351,467],"enclosed":[352],"target":[354],"rat,":[355],"sex":[359],"experimental":[364,372],"animal.":[365],"During":[366],"min":[369,398],"session,":[370],"animal":[373],"could":[374],"explore":[375],"baskets":[377,386],"environment":[380],"ratio":[383],"empty:target":[385],"exploration":[387],"calculated.":[389],"All":[390],"videorecorded":[393],"analyzed":[395],"offline.":[396],"Thirty":[397],"at":[405],"corresponding":[407],"moment":[408],"rats,":[411],"blood":[414,430],"sampled":[415],"decapitation,":[417],"post-test":[424,503],"levels.":[427],"After":[428],"sampling,":[431],"phase":[433],"estrous":[436,462],"cycle":[437],"checked.":[439],"Results:":[440],"proestrous":[444],"ambulated":[445],"less":[446],"field":[453],"than":[454,509,529],"CTL":[455,477],"DEP11":[457,479],"phase.":[463],"Males,":[464],"hand,":[468],"displayed":[469],"reduced":[470],"ratio,":[473],"when":[474,525],"compared":[475],"counterparts.":[480],"The":[481],"test":[483],"elicited":[484],"hormonal":[486],"similar":[490],"all":[492],"groups":[493],"sexes,":[495],"e.g.,":[496],"regardless":[497],"group":[500],"sex,":[502],"levels":[506],"higher":[508,520],"basal.":[510],"Conclusion:":[511],"results":[513],"suggest":[514],"had":[518],"impact":[521],"it":[526],"happened":[527],"earlier":[528],"later":[530],"development,":[532],"an":[534],"evident":[535],"sexual":[536],"dimorphism.":[537]},"counts_by_year":[],"updated_date":"2026-09-25T08:18:29.962427","created_date":"2026-01-10T00:00:00"}