{"id":"https://openalex.org/W7119928131","doi":"https://doi.org/10.14423/smj.0000000000001925","title":"Genomics and Personalized Medicine: The DNA Revolution Reshaping Patient Care by 2035","display_name":"Genomics and Personalized Medicine: The DNA Revolution Reshaping Patient Care by 2035","publication_year":2026,"publication_date":"2026-01-01","ids":{"openalex":"https://openalex.org/W7119928131","doi":"https://doi.org/10.14423/smj.0000000000001925","pmid":"https://pubmed.ncbi.nlm.nih.gov/41511845"},"language":"en","primary_location":{"id":"doi:10.14423/smj.0000000000001925","doi":"https://doi.org/10.14423/smj.0000000000001925","is_oa":false,"landing_page_url":"https://doi.org/10.14423/smj.0000000000001925","pdf_url":null,"source":{"id":"https://openalex.org/S89143414","display_name":"Southern Medical Journal","issn_l":"0038-4348","issn":["0038-4348","1541-8243"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-40","russia-white-list-2"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Southern Medical Journal","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5113411687","display_name":"Ali Waleed Khalid","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I3125470973","display_name":"Istanbul Medipol University","ror":"https://ror.org/037jwzz50","country_code":"TR","type":"education","lineage":["https://openalex.org/I3125470973"]},{"id":"https://openalex.org/I92864154","display_name":"University of Buckingham","ror":"https://ror.org/03kd28f18","country_code":"GB","type":"education","lineage":["https://openalex.org/I92864154"]}],"countries":["GB","TR"],"is_corresponding":false,"raw_author_name":"Ali Waleed Khalid","raw_affiliation_strings":["From the University of Buckingham Medical School, Buckingham, United Kingdom","Medipol University International School of Medicine, Istanbul, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the University of Buckingham Medical School, Buckingham, United Kingdom","institution_ids":["https://openalex.org/I92864154"]},{"raw_affiliation_string":"Medipol University International School of Medicine, Istanbul, Turkey","institution_ids":["https://openalex.org/I3125470973"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006796108","display_name":"Aya Khalid","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I3125470973","display_name":"Istanbul Medipol University","ror":"https://ror.org/037jwzz50","country_code":"TR","type":"education","lineage":["https://openalex.org/I3125470973"]},{"id":"https://openalex.org/I92864154","display_name":"University of Buckingham","ror":"https://ror.org/03kd28f18","country_code":"GB","type":"education","lineage":["https://openalex.org/I92864154"]}],"countries":["GB","TR"],"is_corresponding":false,"raw_author_name":"Aya Khalid","raw_affiliation_strings":["From the University of Buckingham Medical School, Buckingham, United Kingdom","Medipol University International School of Medicine, Istanbul, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the University of Buckingham Medical School, Buckingham, United Kingdom","institution_ids":["https://openalex.org/I92864154"]},{"raw_affiliation_string":"Medipol University International School of Medicine, Istanbul, Turkey","institution_ids":["https://openalex.org/I3125470973"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086064747","display_name":"Sjaak Pouwels","orcid":"https://orcid.org/0000-0002-6390-7692","observed_orcids":["https://orcid.org/0000-0002-6390-7692"]},"institutions":[{"id":"https://openalex.org/I20121455","display_name":"Bielefeld University","ror":"https://ror.org/02hpadn98","country_code":"DE","type":"education","lineage":["https://openalex.org/I20121455"]},{"id":"https://openalex.org/I4210129627","display_name":"Klinikum Lippe","ror":"https://ror.org/02pbsk254","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210129627"]},{"id":"https://openalex.org/I4210149554","display_name":"Elisabeth-TweeSteden Ziekenhuis","ror":"https://ror.org/04gpfvy81","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I4210149554"]}],"countries":["DE","NL"],"is_corresponding":false,"raw_author_name":"Sjaak Pouwels","raw_affiliation_strings":["Department of Intensive Care Medicine, Elisabeth-Tweesteden Hospital, Tilburg, the Netherlands","Department of Surgery, University Bielefeld - Campus Detmold, Klinikum Lippe, Detmold, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Intensive Care Medicine, Elisabeth-Tweesteden Hospital, Tilburg, the Netherlands","institution_ids":["https://openalex.org/I4210149554"]},{"raw_affiliation_string":"Department of Surgery, University Bielefeld - Campus Detmold, Klinikum Lippe, Detmold, Germany","institution_ids":["https://openalex.org/I20121455","https://openalex.org/I4210129627"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5122519511","display_name":"Anurag Agarwal","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1286751378","display_name":"Betsi Cadwaladr University Health Board","ror":"https://ror.org/03awsb125","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1286751378","https://openalex.org/I4210144625"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Anurag Agarwal","raw_affiliation_strings":["Department of General Surgery, Betsi Cadwaladr University Health Board, St Asaph, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of General Surgery, Betsi Cadwaladr University Health Board, St Asaph, United Kingdom","institution_ids":["https://openalex.org/I1286751378"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5104851030","display_name":"Edgar Gelber","orcid":"https://orcid.org/0009-0001-6103-9983","observed_orcids":["https://orcid.org/0009-0001-6103-9983"]},"institutions":[{"id":"https://openalex.org/I1286751378","display_name":"Betsi Cadwaladr University Health Board","ror":"https://ror.org/03awsb125","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1286751378","https://openalex.org/I4210144625"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Edgar Gelber","raw_affiliation_strings":["Department of General Surgery, Betsi Cadwaladr University Health Board, St Asaph, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of General Surgery, Betsi Cadwaladr University Health Board, St Asaph, United Kingdom","institution_ids":["https://openalex.org/I1286751378"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5136023514","display_name":"Anil Lala","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1286751378","display_name":"Betsi Cadwaladr University Health Board","ror":"https://ror.org/03awsb125","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1286751378","https://openalex.org/I4210144625"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Anil Lala","raw_affiliation_strings":["Department of General Surgery, Betsi Cadwaladr University Health Board, St Asaph, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of General Surgery, Betsi Cadwaladr University Health Board, St Asaph, United Kingdom","institution_ids":["https://openalex.org/I1286751378"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5122421145","display_name":"Ahmed R. Ahmed","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Ahmed R. Ahmed","raw_affiliation_strings":["Department of Bariatric Surgery, Imperial College London, London, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Bariatric Surgery, Imperial College London, London, United Kingdom","institution_ids":["https://openalex.org/I47508984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5122650137","display_name":"Wah Yang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210162753","display_name":"First Affiliated Hospital of Jinan University","ror":"https://ror.org/05d5vvz89","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210162753"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wah Yang","raw_affiliation_strings":["Department of Metabolic and Bariatric Surgery, The First Affiliated Hospital of Jinan University, Guangzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Metabolic and Bariatric Surgery, The First Affiliated Hospital of Jinan University, Guangzhou, China","institution_ids":["https://openalex.org/I4210162753"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5122587090","display_name":"Suhaib Ahmad","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1286751378","display_name":"Betsi Cadwaladr University Health Board","ror":"https://ror.org/03awsb125","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1286751378","https://openalex.org/I4210144625"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Suhaib Ahmad","raw_affiliation_strings":["Department of General Surgery, Betsi Cadwaladr University Health Board, St Asaph, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of General Surgery, Betsi Cadwaladr University Health Board, St Asaph, United Kingdom","institution_ids":["https://openalex.org/I1286751378"]}]}],"institutions":[],"countries_distinct_count":5,"institutions_distinct_count":8,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.8656,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.67529618,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":95,"max":96},"biblio":{"volume":"119","issue":"1","first_page":"39","last_page":"43"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11636","display_name":"Artificial Intelligence in Healthcare and Education","score":0.48539999127388,"subfield":{"id":"https://openalex.org/subfields/2718","display_name":"Health Informatics"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11636","display_name":"Artificial Intelligence in Healthcare and Education","score":0.48539999127388,"subfield":{"id":"https://openalex.org/subfields/2718","display_name":"Health Informatics"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11642","display_name":"Genomics and Rare Diseases","score":0.2808000147342682,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11287","display_name":"Cancer Genomics and Diagnostics","score":0.09309999644756317,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/genomics","display_name":"genomics","score":0.6200000047683716},{"id":"https://openalex.org/keywords/personalized-medicine","display_name":"personalized medicine","score":0.9259999990463257},{"id":"https://openalex.org/keywords/precision-medicine","display_name":"precision medicine","score":0.7860000133514404},{"id":"https://openalex.org/keywords/artificial-intelligence-in-genomics","display_name":"artificial intelligence in genomics","score":0.8529999852180481},{"id":"https://openalex.org/keywords/whole-genome-sequencing","display_name":"whole genome sequencing","score":0.9879999756813049},{"id":"https://openalex.org/keywords/single-cell-genomics","display_name":"single-cell genomics","score":0.9990000128746033},{"id":"https://openalex.org/keywords/pharmacogenomics","display_name":"pharmacogenomics","score":1.0},{"id":"https://openalex.org/keywords/genome-editing","display_name":"genome editing","score":0.9879999756813049},{"id":"https://openalex.org/keywords/crispr","display_name":"CRISPR","score":0.9940000176429749},{"id":"https://openalex.org/keywords/epigenomics","display_name":"epigenomics","score":0.9700000286102295},{"id":"https://openalex.org/keywords/liquid-biopsy","display_name":"liquid biopsy","score":0.9860000014305115},{"id":"https://openalex.org/keywords/early-disease-detection","display_name":"early disease detection","score":0.8349999785423279},{"id":"https://openalex.org/keywords/genomic-data-privacy","display_name":"genomic data privacy","score":0.8289999961853027},{"id":"https://openalex.org/keywords/algorithmic-bias","display_name":"algorithmic bias","score":0.996999979019165},{"id":"https://openalex.org/keywords/uk-biobank","display_name":"UK Biobank","score":0.7929999828338623},{"id":"https://openalex.org/keywords/100-000-genomes-project","display_name":"100,000 Genomes Project","score":1.0},{"id":"https://openalex.org/keywords/genetic-disorders","display_name":"genetic disorders","score":0.5920000076293945}],"concepts":[{"id":"https://openalex.org/C32220436","wikidata":"https://www.wikidata.org/wiki/Q2072214","display_name":"Personalized medicine","level":2,"score":0.733299970626831},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6935999989509583},{"id":"https://openalex.org/C189206191","wikidata":"https://www.wikidata.org/wiki/Q222046","display_name":"Genomics","level":4,"score":0.6747999787330627},{"id":"https://openalex.org/C116567970","wikidata":"https://www.wikidata.org/wiki/Q864217","display_name":"Biobank","level":2,"score":0.6653000116348267},{"id":"https://openalex.org/C163763905","wikidata":"https://www.wikidata.org/wiki/Q17075943","display_name":"Precision medicine","level":2,"score":0.6341999769210815},{"id":"https://openalex.org/C70587473","wikidata":"https://www.wikidata.org/wiki/Q7834111","display_name":"Transformative learning","level":2,"score":0.5097000002861023},{"id":"https://openalex.org/C160735492","wikidata":"https://www.wikidata.org/wiki/Q31207","display_name":"Health care","level":2,"score":0.48820000886917114},{"id":"https://openalex.org/C75684735","wikidata":"https://www.wikidata.org/wiki/Q858810","display_name":"Big data","level":2,"score":0.4392000138759613},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.4293000102043152},{"id":"https://openalex.org/C2522767166","wikidata":"https://www.wikidata.org/wiki/Q2374463","display_name":"Data science","level":1,"score":0.4058000147342682},{"id":"https://openalex.org/C121912465","wikidata":"https://www.wikidata.org/wiki/Q3589153","display_name":"Epigenomics","level":5,"score":0.39800000190734863},{"id":"https://openalex.org/C2992545694","wikidata":"https://www.wikidata.org/wiki/Q1071953","display_name":"Genomic medicine","level":2,"score":0.39489999413490295},{"id":"https://openalex.org/C164614171","wikidata":"https://www.wikidata.org/wiki/Q5204775","display_name":"DECIPHER","level":2,"score":0.3815000057220459},{"id":"https://openalex.org/C2779965156","wikidata":"https://www.wikidata.org/wiki/Q5227350","display_name":"Data sharing","level":3,"score":0.36800000071525574},{"id":"https://openalex.org/C207267971","wikidata":"https://www.wikidata.org/wiki/Q120208","display_name":"Emerging technologies","level":2,"score":0.35600000619888306},{"id":"https://openalex.org/C179786068","wikidata":"https://www.wikidata.org/wiki/Q16257937","display_name":"Molecular diagnostics","level":2,"score":0.3531000018119812},{"id":"https://openalex.org/C183003079","wikidata":"https://www.wikidata.org/wiki/Q1000371","display_name":"Personalization","level":2,"score":0.31839999556541443},{"id":"https://openalex.org/C2777617010","wikidata":"https://www.wikidata.org/wiki/Q18957","display_name":"Mainstream","level":2,"score":0.3125},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.3068999946117401},{"id":"https://openalex.org/C51915194","wikidata":"https://www.wikidata.org/wiki/Q17075487","display_name":"Point of care","level":2,"score":0.3052999973297119},{"id":"https://openalex.org/C191630685","wikidata":"https://www.wikidata.org/wiki/Q4027615","display_name":"Informatics","level":2,"score":0.2736999988555908},{"id":"https://openalex.org/C128544194","wikidata":"https://www.wikidata.org/wiki/Q474859","display_name":"Translational research","level":2,"score":0.27090001106262207},{"id":"https://openalex.org/C2910417920","wikidata":"https://www.wikidata.org/wiki/Q4116434","display_name":"Patient privacy","level":3,"score":0.2685000002384186},{"id":"https://openalex.org/C2989236134","wikidata":"https://www.wikidata.org/wiki/Q31207","display_name":"Patient care","level":2,"score":0.2614000141620636},{"id":"https://openalex.org/C3020000666","wikidata":"https://www.wikidata.org/wiki/Q17112037","display_name":"Bench to bedside","level":2,"score":0.26089999079704285},{"id":"https://openalex.org/C2779473830","wikidata":"https://www.wikidata.org/wiki/Q1540899","display_name":"MEDLINE","level":2,"score":0.25920000672340393},{"id":"https://openalex.org/C145642194","wikidata":"https://www.wikidata.org/wiki/Q870895","display_name":"Health informatics","level":3,"score":0.25699999928474426},{"id":"https://openalex.org/C39389867","wikidata":"https://www.wikidata.org/wiki/Q380767","display_name":"Corporate governance","level":2,"score":0.2524000108242035}],"mesh":[{"descriptor_ui":"D000097103","descriptor_name":"Digital Health","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001185","descriptor_name":"Artificial Intelligence","qualifier_ui":"Q000639","qualifier_name":"trends","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010597","descriptor_name":"Pharmacogenetics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":"Q000639","qualifier_name":"trends","is_major_topic":true},{"descriptor_ui":"D057285","descriptor_name":"Precision Medicine","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D057285","descriptor_name":"Precision Medicine","qualifier_ui":"Q000639","qualifier_name":"trends","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.14423/smj.0000000000001925","doi":"https://doi.org/10.14423/smj.0000000000001925","is_oa":false,"landing_page_url":"https://doi.org/10.14423/smj.0000000000001925","pdf_url":null,"source":{"id":"https://openalex.org/S89143414","display_name":"Southern Medical Journal","issn_l":"0038-4348","issn":["0038-4348","1541-8243"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-40","russia-white-list-2"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Southern Medical Journal","raw_type":"journal-article"},{"id":"pmid:41511845","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/41511845","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Southern medical journal","raw_type":"Journal Article"},{"id":"pmh:oai:pub.uni-bielefeld.de:3012848","doi":null,"is_oa":false,"landing_page_url":"https://pub.uni-bielefeld.de/record/3012848","pdf_url":null,"source":{"id":"https://openalex.org/S4306401624","display_name":"Publikationen an der Universit\u00e4t Bielefeld (Universit\u00e4t Bielefeld)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I20121455","host_organization_name":"Bielefeld University","host_organization_lineage":["https://openalex.org/I20121455"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"http://purl.org/coar/resource_type/c_6501"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9537000060081482}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":48,"referenced_works":["https://openalex.org/W383907825","https://openalex.org/W1999808841","https://openalex.org/W2007833428","https://openalex.org/W2032448018","https://openalex.org/W2060427373","https://openalex.org/W2114651342","https://openalex.org/W2468349064","https://openalex.org/W2743416243","https://openalex.org/W2763574125","https://openalex.org/W2789970635","https://openalex.org/W2887629426","https://openalex.org/W2895486342","https://openalex.org/W2896913847","https://openalex.org/W2902802452","https://openalex.org/W2905810301","https://openalex.org/W2913467662","https://openalex.org/W2941821853","https://openalex.org/W2951054376","https://openalex.org/W3012901598","https://openalex.org/W3038072559","https://openalex.org/W3039614857","https://openalex.org/W3129249129","https://openalex.org/W3138506360","https://openalex.org/W3146345129","https://openalex.org/W3172362366","https://openalex.org/W3196116757","https://openalex.org/W3206540014","https://openalex.org/W3212464243","https://openalex.org/W4200353185","https://openalex.org/W4200534512","https://openalex.org/W4251475434","https://openalex.org/W4282935413","https://openalex.org/W4289223986","https://openalex.org/W4294916331","https://openalex.org/W4304618489","https://openalex.org/W4311141709","https://openalex.org/W4313379896","https://openalex.org/W4315865162","https://openalex.org/W4376637282","https://openalex.org/W4385377627","https://openalex.org/W4386958277","https://openalex.org/W4387472633","https://openalex.org/W4389203612","https://openalex.org/W4392303996","https://openalex.org/W4392747035","https://openalex.org/W4403692724","https://openalex.org/W4404893996","https://openalex.org/W4406613958"],"related_works":["https://openalex.org/W7147480710","https://openalex.org/W7171828376","https://openalex.org/W7223153968","https://openalex.org/W7160195757","https://openalex.org/W4416566857","https://openalex.org/W7163376717","https://openalex.org/W4404007654","https://openalex.org/W7148795208","https://openalex.org/W7163688214","https://openalex.org/W7163648185"],"abstract_inverted_index":{"The":[0,77],"rapid":[1],"evolution":[2],"of":[3,169,216,236],"genomic":[4,65,133,159,237],"technologies":[5],"is":[6,58,83],"poised":[7],"to":[8,23,211,229],"transform":[9],"patient":[10,72],"care":[11],"during":[12],"the":[13,147,151,166,213,224,231],"next":[14],"decade,":[15],"integrating":[16,158],"precision":[17],"medicine":[18,195],"with":[19],"artificial":[20],"intelligence":[21],"(AI)":[22],"enhance":[24],"diagnostic":[25],"accuracy,":[26],"therapeutic":[27],"decision":[28],"making,":[29],"and":[30,47,50,74,81,95,101,115,128,136,150,200,205,233],"personalized":[31,201],"healthcare":[32],"strategies.":[33],"This":[34,139,221],"review":[35,140,222],"explores":[36],"key":[37],"advancements":[38],"in":[39,64,125,180,190],"genomics,":[40,45],"including":[41],"whole-genome":[42],"sequencing,":[43],"single-cell":[44],"pharmacogenomics,":[46],"gene-editing":[48,170],"technologies,":[49,219],"their":[51],"potential":[52,176],"impact":[53],"on":[54],"clinical":[55,192,232],"practice.":[56],"AI":[57,80],"emerging":[59],"as":[60,91,146,155,173],"a":[61,197],"critical":[62],"tool":[63],"data":[66,134,160],"interpretation,":[67],"improving":[68],"disease":[69,107],"risk":[70],"prediction,":[71],"stratification,":[73],"drug-response":[75],"assessments.":[76],"synergy":[78],"between":[79],"genomics":[82,185],"fostering":[84],"novel":[85],"insights":[86],"into":[87,161],"complex":[88],"diseases":[89],"such":[90,145,172],"cancer,":[92],"cardiovascular":[93],"conditions,":[94],"neurodegenerative":[96],"disorders.":[97],"In":[98],"addition,":[99],"epigenomics":[100],"liquid":[102],"biopsies":[103],"are":[104],"expanding":[105],"early":[106],"detection":[108],"capabilities,":[109],"allowing":[110],"for":[111,157,177,226],"minimally":[112],"invasive":[113],"diagnostics":[114],"real-time":[116],"treatment":[117],"monitoring.":[118],"Despite":[119],"these":[120,217],"promising":[121],"developments,":[122],"challenges":[123],"remain":[124],"accessibility,":[126],"cost,":[127],"ethical":[129,206],"considerations,":[130],"particularly":[131],"regarding":[132],"privacy":[135],"algorithmic":[137],"bias.":[138],"highlights":[141],"ongoing":[142],"global":[143],"initiatives,":[144],"UK":[148],"Biobank":[149],"100,000":[152],"Genomes":[153],"Project,":[154],"models":[156],"mainstream":[162],"health":[163],"care.":[164],"Furthermore,":[165],"widespread":[167],"adoption":[168],"techniques":[171],"CRISPR":[174],"holds":[175],"curative":[178],"interventions":[179],"hereditary":[181],"diseases.":[182],"By":[183],"2030,":[184],"will":[186],"likely":[187],"be":[188,209],"embedded":[189],"routine":[191],"practice,":[193],"shifting":[194],"toward":[196],"predictive,":[198],"preventive,":[199],"model.":[202],"Equitable":[203],"access":[204],"governance":[207],"must":[208],"prioritized":[210],"ensure":[212],"responsible":[214],"implementation":[215],"transformative":[218],"however.":[220],"underscores":[223],"need":[225],"interdisciplinary":[227],"collaboration":[228],"maximize":[230],"societal":[234],"benefits":[235],"innovation.":[238]},"counts_by_year":[{"year":2026,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2026-01-10T00:00:00"}