{"id":"https://openalex.org/W7119086875","doi":"https://doi.org/10.1002/1545-5017.70019","title":"Implementation Science Methodology for the Successful Introduction of High\u2010Dose Methotrexate for the Treatment of Pediatric Mature B\u2010Cell Non\u2010Hodgkin Lymphoma in a Resource\u2010Limited Setting","display_name":"Implementation Science Methodology for the Successful Introduction of High\u2010Dose Methotrexate for the Treatment of Pediatric Mature B\u2010Cell Non\u2010Hodgkin Lymphoma in a Resource\u2010Limited Setting","publication_year":2026,"publication_date":"2026-01-05","ids":{"openalex":"https://openalex.org/W7119086875","doi":"https://doi.org/10.1002/1545-5017.70019","pmid":"https://pubmed.ncbi.nlm.nih.gov/41491667"},"language":"en","primary_location":{"id":"doi:10.1002/1545-5017.70019","doi":"https://doi.org/10.1002/1545-5017.70019","is_oa":false,"landing_page_url":"https://doi.org/10.1002/1545-5017.70019","pdf_url":null,"source":{"id":"https://openalex.org/S119714264","display_name":"Pediatric Blood & Cancer","issn_l":"1545-5009","issn":["1545-5009","1545-5017"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pediatric Blood & Cancer","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5052990056","display_name":"Hutton Chapman","orcid":"https://orcid.org/0000-0001-5574-8532","observed_orcids":["https://orcid.org/0000-0001-5574-8532"]},"institutions":[{"id":"https://openalex.org/I170897317","display_name":"Duke University","ror":"https://ror.org/00py81415","country_code":"US","type":"education","lineage":["https://openalex.org/I170897317"]},{"id":"https://openalex.org/I4210153043","display_name":"Duke University Hospital","ror":"https://ror.org/04bct7p84","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876","https://openalex.org/I4210153043"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Hutton Chapman","raw_affiliation_strings":["Duke Global Health Institute  Durham North Carolina USA","Duke University Hospital  Durham North Carolina USA"],"raw_orcid":"https://orcid.org/0000-0001-5574-8532","affiliations":[{"raw_affiliation_string":"Duke Global Health Institute  Durham North Carolina USA","institution_ids":["https://openalex.org/I170897317"]},{"raw_affiliation_string":"Duke University Hospital  Durham North Carolina USA","institution_ids":["https://openalex.org/I4210153043"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5130825492","display_name":"Paul Shadrack Ntemi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I273065767","display_name":"Catholic University of Health and Allied Sciences","ror":"https://ror.org/015qmyq14","country_code":"TZ","type":"education","lineage":["https://openalex.org/I273065767"]},{"id":"https://openalex.org/I4210148991","display_name":"Bugando Medical Centre","ror":"https://ror.org/05h7pem82","country_code":"TZ","type":"healthcare","lineage":["https://openalex.org/I4210148991"]}],"countries":["TZ"],"is_corresponding":false,"raw_author_name":"Paul S. Ntemi","raw_affiliation_strings":["Bugando Medical Centre  Mwanza Tanzania","Catholic University of Allied and Health Sciences  Mwanza Tanzania"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bugando Medical Centre  Mwanza Tanzania","institution_ids":["https://openalex.org/I4210148991"]},{"raw_affiliation_string":"Catholic University of Allied and Health Sciences  Mwanza Tanzania","institution_ids":["https://openalex.org/I273065767"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5122199456","display_name":"Richard Mahene","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210148991","display_name":"Bugando Medical Centre","ror":"https://ror.org/05h7pem82","country_code":"TZ","type":"healthcare","lineage":["https://openalex.org/I4210148991"]}],"countries":["TZ"],"is_corresponding":false,"raw_author_name":"Richard Mahene","raw_affiliation_strings":["Bugando Medical Centre  Mwanza Tanzania"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bugando Medical Centre  Mwanza Tanzania","institution_ids":["https://openalex.org/I4210148991"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5122275576","display_name":"Dativa Zelama","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210148991","display_name":"Bugando Medical Centre","ror":"https://ror.org/05h7pem82","country_code":"TZ","type":"healthcare","lineage":["https://openalex.org/I4210148991"]}],"countries":["TZ"],"is_corresponding":false,"raw_author_name":"Dativa Zelama","raw_affiliation_strings":["Bugando Medical Centre  Mwanza Tanzania"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bugando Medical Centre  Mwanza Tanzania","institution_ids":["https://openalex.org/I4210148991"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011839044","display_name":"Jacqueline Kamanga","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210148991","display_name":"Bugando Medical Centre","ror":"https://ror.org/05h7pem82","country_code":"TZ","type":"healthcare","lineage":["https://openalex.org/I4210148991"]}],"countries":["TZ"],"is_corresponding":false,"raw_author_name":"Jacqueline Kamanga","raw_affiliation_strings":["Bugando Medical Centre  Mwanza Tanzania"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bugando Medical Centre  Mwanza Tanzania","institution_ids":["https://openalex.org/I4210148991"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069225483","display_name":"Goodluck Nchasi","orcid":"https://orcid.org/0000-0002-1002-0596","observed_orcids":["https://orcid.org/0000-0002-1002-0596"]},"institutions":[{"id":"https://openalex.org/I4210148991","display_name":"Bugando Medical Centre","ror":"https://ror.org/05h7pem82","country_code":"TZ","type":"healthcare","lineage":["https://openalex.org/I4210148991"]}],"countries":["TZ"],"is_corresponding":false,"raw_author_name":"Goodluck Nchasi","raw_affiliation_strings":["Bugando Medical Centre  Mwanza Tanzania"],"raw_orcid":"https://orcid.org/0000-0002-1002-0596","affiliations":[{"raw_affiliation_string":"Bugando Medical Centre  Mwanza Tanzania","institution_ids":["https://openalex.org/I4210148991"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065692914","display_name":"Heronima Joas Kashaigili","orcid":"https://orcid.org/0000-0002-1295-7921","observed_orcids":["https://orcid.org/0000-0002-1295-7921"]},"institutions":[{"id":"https://openalex.org/I273065767","display_name":"Catholic University of Health and Allied Sciences","ror":"https://ror.org/015qmyq14","country_code":"TZ","type":"education","lineage":["https://openalex.org/I273065767"]},{"id":"https://openalex.org/I4210148991","display_name":"Bugando Medical Centre","ror":"https://ror.org/05h7pem82","country_code":"TZ","type":"healthcare","lineage":["https://openalex.org/I4210148991"]}],"countries":["TZ"],"is_corresponding":false,"raw_author_name":"Heronima Kashaigili","raw_affiliation_strings":["Bugando Medical Centre  Mwanza Tanzania","Catholic University of Allied and Health Sciences  Mwanza Tanzania"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bugando Medical Centre  Mwanza Tanzania","institution_ids":["https://openalex.org/I4210148991"]},{"raw_affiliation_string":"Catholic University of Allied and Health Sciences  Mwanza Tanzania","institution_ids":["https://openalex.org/I273065767"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5084466095","display_name":"Kristin Schroeder","orcid":"https://orcid.org/0000-0002-6433-6174","observed_orcids":["https://orcid.org/0000-0002-6433-6174"]},"institutions":[{"id":"https://openalex.org/I170897317","display_name":"Duke University","ror":"https://ror.org/00py81415","country_code":"US","type":"education","lineage":["https://openalex.org/I170897317"]},{"id":"https://openalex.org/I4210153043","display_name":"Duke University Hospital","ror":"https://ror.org/04bct7p84","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876","https://openalex.org/I4210153043"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kristin Schroeder","raw_affiliation_strings":["Duke Global Health Institute  Durham North Carolina USA","Duke University Hospital  Durham North Carolina USA"],"raw_orcid":"https://orcid.org/0000-0002-6433-6174","affiliations":[{"raw_affiliation_string":"Duke Global Health Institute  Durham North Carolina USA","institution_ids":["https://openalex.org/I170897317"]},{"raw_affiliation_string":"Duke University Hospital  Durham North Carolina USA","institution_ids":["https://openalex.org/I4210153043"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5052990056"],"corresponding_institution_ids":["https://openalex.org/I170897317","https://openalex.org/I4210153043"],"apc_list":{"value":4640,"currency":"USD","value_usd":4640},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.01272696,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"73","issue":"3","first_page":"e70019","last_page":"e70019"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10629","display_name":"Health Policy Implementation Science","score":0.9009000062942505,"subfield":{"id":"https://openalex.org/subfields/3600","display_name":"General Health Professions"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10629","display_name":"Health Policy Implementation Science","score":0.9009000062942505,"subfield":{"id":"https://openalex.org/subfields/3600","display_name":"General Health Professions"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10185","display_name":"Lymphoma Diagnosis and Treatment","score":0.04479999840259552,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10950","display_name":"Acute Lymphoblastic Leukemia research","score":0.022700000554323196,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/high-dose-methotrexate","display_name":"high-dose methotrexate","score":0.9909999966621399},{"id":"https://openalex.org/keywords/implementation-science","display_name":"implementation science","score":0.8889999985694885},{"id":"https://openalex.org/keywords/resource-limited-settings","display_name":"resource-limited settings","score":0.9279999732971191},{"id":"https://openalex.org/keywords/decision-support-system","display_name":"decision support system","score":0.7400000095367432},{"id":"https://openalex.org/keywords/stakeholder-engagement","display_name":"stakeholder engagement","score":0.7160000205039978},{"id":"https://openalex.org/keywords/cost-analysis","display_name":"cost analysis","score":0.6949999928474426},{"id":"https://openalex.org/keywords/resource-mapping","display_name":"resource mapping","score":0.7049999833106995},{"id":"https://openalex.org/keywords/treatment-related-toxicity","display_name":"treatment toxicity","score":0.5320000052452087},{"id":"https://openalex.org/keywords/low-and-middle-income-countries","display_name":"low- and middle-income countries","score":0.8240000009536743}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.949400007724762},{"id":"https://openalex.org/C2781059491","wikidata":"https://www.wikidata.org/wiki/Q422232","display_name":"Methotrexate","level":2,"score":0.676800012588501},{"id":"https://openalex.org/C2779338263","wikidata":"https://www.wikidata.org/wiki/Q208414","display_name":"Lymphoma","level":2,"score":0.4715000092983246},{"id":"https://openalex.org/C2779473830","wikidata":"https://www.wikidata.org/wiki/Q1540899","display_name":"MEDLINE","level":2,"score":0.4426000118255615},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.4323999881744385},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.35929998755455017},{"id":"https://openalex.org/C2909143077","wikidata":"https://www.wikidata.org/wiki/Q5097977","display_name":"Pediatric oncology","level":3,"score":0.32100000977516174},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.31369999051094055},{"id":"https://openalex.org/C2992972558","wikidata":"https://www.wikidata.org/wiki/Q2509220","display_name":"Blood cancer","level":3,"score":0.2881999909877777},{"id":"https://openalex.org/C19527891","wikidata":"https://www.wikidata.org/wiki/Q1120908","display_name":"Medical physics","level":1,"score":0.265500009059906}],"mesh":[{"descriptor_ui":"D000077626","descriptor_name":"Implementation Science","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000077626","descriptor_name":"Implementation Science","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000092943","descriptor_name":"Resource-Limited Settings","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000092943","descriptor_name":"Resource-Limited Settings","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000964","descriptor_name":"Antimetabolites, Antineoplastic","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D000964","descriptor_name":"Antimetabolites, Antineoplastic","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D000964","descriptor_name":"Antimetabolites, Antineoplastic","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D000964","descriptor_name":"Antimetabolites, Antineoplastic","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002675","descriptor_name":"Child, Preschool","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002675","descriptor_name":"Child, Preschool","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003906","descriptor_name":"Developing Countries","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003906","descriptor_name":"Developing Countries","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006295","descriptor_name":"Health Resources","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006295","descriptor_name":"Health Resources","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008727","descriptor_name":"Methotrexate","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D008727","descriptor_name":"Methotrexate","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D008727","descriptor_name":"Methotrexate","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D008727","descriptor_name":"Methotrexate","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D013636","descriptor_name":"Tanzania","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013636","descriptor_name":"Tanzania","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016393","descriptor_name":"Lymphoma, B-Cell","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D016393","descriptor_name":"Lymphoma, B-Cell","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D016393","descriptor_name":"Lymphoma, B-Cell","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D016393","descriptor_name":"Lymphoma, B-Cell","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1002/1545-5017.70019","doi":"https://doi.org/10.1002/1545-5017.70019","is_oa":false,"landing_page_url":"https://doi.org/10.1002/1545-5017.70019","pdf_url":null,"source":{"id":"https://openalex.org/S119714264","display_name":"Pediatric Blood & Cancer","issn_l":"1545-5009","issn":["1545-5009","1545-5017"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pediatric Blood & Cancer","raw_type":"journal-article"},{"id":"pmid:41491667","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/41491667","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pediatric blood & cancer","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9907000064849854,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[{"score":0.7154521942138672,"display_name":"No poverty","id":"https://metadata.un.org/sdg/1"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":13,"referenced_works":["https://openalex.org/W1974475006","https://openalex.org/W2051692320","https://openalex.org/W2084312498","https://openalex.org/W2337911387","https://openalex.org/W2623709470","https://openalex.org/W2803165542","https://openalex.org/W2912859263","https://openalex.org/W2917196837","https://openalex.org/W2991906087","https://openalex.org/W3031891765","https://openalex.org/W3081190106","https://openalex.org/W4360599979","https://openalex.org/W4400013942"],"related_works":[],"abstract_inverted_index":{"BACKGROUND:":[0],"Despite":[1],"the":[2,33,45,72,229,234],"excellent":[3],"outcomes":[4,16],"achieved":[5],"for":[6,32,47,103,233],"pediatric":[7,237],"mature":[8],"B-cell":[9],"non-Hodgkin":[10],"lymphoma":[11],"(MB-NHL)":[12],"in":[13,20,40,62,79,87,109,179,239],"high-income":[14],"countries,":[15],"remain":[17],"very":[18],"poor":[19],"low-":[21],"and":[22,134,137,146,154,167,206],"middle-income":[23],"countries.":[24],"High-dose":[25],"methotrexate":[26],"(HD-MTX),":[27],"which":[28],"is":[29,35],"highly":[30],"efficacious":[31],"disease,":[34],"still":[36],"not":[37],"commonly":[38],"used":[39,74],"low-resource":[41],"settings":[42],"due":[43],"to":[44,69,75,92,97,101,124,194],"potential":[46],"treatment-associated":[48],"toxicity.":[49],"Though":[50],"there":[51,65],"have":[52,191,204],"been":[53,192,215],"more":[54],"recent":[55],"reports":[56,68],"of":[57,60,107,164,171,181,184,189,198,220,228,231,236],"successful":[58],"use":[59,170,219,230],"HD-MTX":[61,78,108,174,190,232],"resource-limited":[63,111,241],"settings,":[64],"are":[66],"no":[67],"date":[70],"regarding":[71],"methodology":[73,96,223],"safely":[76],"introduce":[77],"these":[80],"environments.":[81],"Subsequently,":[82],"at":[83],"our":[84],"treatment":[85,235],"center":[86],"northern":[88],"Tanzania,":[89],"we":[90],"endeavored":[91],"utilize":[93],"implementation":[94,128,221],"science":[95,222],"elucidate":[98],"generalizable":[99],"methods":[100],"allow":[102],"a":[104,110,121,172,195,225,240],"safe":[105],"introduction":[106,227],"setting.":[112,242],"PROCEDURE:":[113],"The":[114,218],"Active":[115],"Implementation":[116],"Frameworks":[117],"were":[118,140,144,159],"utilized":[119],"as":[120],"starting":[122],"point":[123],"generate":[125],"an":[126],"initial":[127],"plan.":[129],"Intervention":[130],"fit":[131],"was":[132],"assessed,":[133],"resource":[135],"mapping":[136],"cost":[138],"analysis":[139],"completed.":[141],"Key":[142],"stakeholders":[143],"identified":[145],"engaged.":[147],"Novel":[148],"educational":[149],"strategies,":[150],"decision":[151],"support":[152],"tools,":[153],"protocol":[155,177,202],"fidelity":[156],"monitoring":[157],"systems":[158],"developed.":[160],"RESULTS:":[161],"Following":[162],"completion":[163],"all":[165],"planning":[166],"education":[168],"activities,":[169],"new":[173],"containing":[175],"MB-NHL":[176,238],"began":[178],"October":[180],"2024.":[182],"As":[183],"June":[185],"2025,":[186],"27":[187],"cycles":[188],"given":[193],"cumulative":[196],"total":[197],"10":[199],"patients.":[200],"Few":[201],"deviations":[203],"occurred,":[205],"only":[207],"one":[208],"Grade":[209],"III":[210],"non-hematologic":[211],"adverse":[212],"event":[213],"has":[214],"reported.":[216],"CONCLUSIONS:":[217],"allowed":[224],"careful":[226]},"counts_by_year":[],"updated_date":"2026-10-14T16:39:01.820549","created_date":"2026-01-08T00:00:00"}