{"id":"https://openalex.org/W7119018022","doi":"https://doi.org/10.3390/jpm16010038","title":"Long COVID Does Not Impair Hemodynamic, Vascular, or Autonomic Responses to Maximal Exercise: Sex-Stratified Study in Young Adults","display_name":"Long COVID Does Not Impair Hemodynamic, Vascular, or Autonomic Responses to Maximal Exercise: Sex-Stratified Study in Young Adults","publication_year":2026,"publication_date":"2026-01-07","ids":{"openalex":"https://openalex.org/W7119018022","doi":"https://doi.org/10.3390/jpm16010038","pmid":"https://pubmed.ncbi.nlm.nih.gov/41590531"},"language":"en","primary_location":{"id":"doi:10.3390/jpm16010038","doi":"https://doi.org/10.3390/jpm16010038","is_oa":true,"landing_page_url":"https://doi.org/10.3390/jpm16010038","pdf_url":"https://www.mdpi.com/2075-4426/16/1/38/pdf","source":{"id":"https://openalex.org/S2736780684","display_name":"Journal of Personalized Medicine","issn_l":"2075-4426","issn":["2075-4426"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","erih-plus","norway-1"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Personalized Medicine","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.mdpi.com/2075-4426/16/1/38/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5010405951","display_name":"Carla Nascimento dos Santos Rodrigues","orcid":"https://orcid.org/0000-0001-9004-8953","observed_orcids":["https://orcid.org/0000-0001-9004-8953"]},"institutions":[{"id":"https://openalex.org/I177909021","display_name":"Universidade Federal de S\u00e3o Carlos","ror":"https://ror.org/00qdc6m37","country_code":"BR","type":"education","lineage":["https://openalex.org/I177909021"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Carla Nascimento dos Santos Rodrigues","raw_affiliation_strings":["Laboratory of Clinical Exercise Physiology, Department of Physiological Sciences, Federal University of S\u00e3o Carlos, S\u00e3o Carlos 13565-905, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Clinical Exercise Physiology, Department of Physiological Sciences, Federal University of S\u00e3o Carlos, S\u00e3o Carlos 13565-905, Brazil","institution_ids":["https://openalex.org/I177909021"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5118847700","display_name":"Fernanda Rico Angelotto","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I177909021","display_name":"Universidade Federal de S\u00e3o Carlos","ror":"https://ror.org/00qdc6m37","country_code":"BR","type":"education","lineage":["https://openalex.org/I177909021"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Fernanda Rico Angelotto","raw_affiliation_strings":["Laboratory of Clinical Exercise Physiology, Department of Physiological Sciences, Federal University of S\u00e3o Carlos, S\u00e3o Carlos 13565-905, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Clinical Exercise Physiology, Department of Physiological Sciences, Federal University of S\u00e3o Carlos, S\u00e3o Carlos 13565-905, Brazil","institution_ids":["https://openalex.org/I177909021"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081173732","display_name":"Vit\u00f3ria Luiz Diotto","orcid":"https://orcid.org/0009-0002-7686-0202","observed_orcids":["https://orcid.org/0009-0002-7686-0202"]},"institutions":[{"id":"https://openalex.org/I177909021","display_name":"Universidade Federal de S\u00e3o Carlos","ror":"https://ror.org/00qdc6m37","country_code":"BR","type":"education","lineage":["https://openalex.org/I177909021"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Vit\u00f3ria Luiz Diotto","raw_affiliation_strings":["Laboratory of Clinical Exercise Physiology, Department of Physiological Sciences, Federal University of S\u00e3o Carlos, S\u00e3o Carlos 13565-905, Brazil"],"raw_orcid":"https://orcid.org/0009-0002-7686-0202","affiliations":[{"raw_affiliation_string":"Laboratory of Clinical Exercise Physiology, Department of Physiological Sciences, Federal University of S\u00e3o Carlos, S\u00e3o Carlos 13565-905, Brazil","institution_ids":["https://openalex.org/I177909021"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5122269298","display_name":"Daniel da Motta Cristofoletti","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I177909021","display_name":"Universidade Federal de S\u00e3o Carlos","ror":"https://ror.org/00qdc6m37","country_code":"BR","type":"education","lineage":["https://openalex.org/I177909021"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Daniel da Motta Cristofoletti","raw_affiliation_strings":["Laboratory of Clinical Exercise Physiology, Department of Physiological Sciences, Federal University of S\u00e3o Carlos, S\u00e3o Carlos 13565-905, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Clinical Exercise Physiology, Department of Physiological Sciences, Federal University of S\u00e3o Carlos, S\u00e3o Carlos 13565-905, Brazil","institution_ids":["https://openalex.org/I177909021"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051336951","display_name":"Tatiana Oliveira Passos de Ara\u00fajo","orcid":"https://orcid.org/0000-0002-9376-2586","observed_orcids":["https://orcid.org/0000-0002-9376-2586"]},"institutions":[{"id":"https://openalex.org/I177909021","display_name":"Universidade Federal de S\u00e3o Carlos","ror":"https://ror.org/00qdc6m37","country_code":"BR","type":"education","lineage":["https://openalex.org/I177909021"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Tatiana Oliveira Passos de Ara\u00fajo","raw_affiliation_strings":["Laboratory of Clinical Exercise Physiology, Department of Physiological Sciences, Federal University of S\u00e3o Carlos, S\u00e3o Carlos 13565-905, Brazil"],"raw_orcid":"https://orcid.org/0000-0002-9376-2586","affiliations":[{"raw_affiliation_string":"Laboratory of Clinical Exercise Physiology, Department of Physiological Sciences, Federal University of S\u00e3o Carlos, S\u00e3o Carlos 13565-905, Brazil","institution_ids":["https://openalex.org/I177909021"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102824961","display_name":"Marco Antonio de Lima","orcid":"https://orcid.org/0000-0002-7530-0513","observed_orcids":["https://orcid.org/0000-0002-7530-0513"]},"institutions":[{"id":"https://openalex.org/I177909021","display_name":"Universidade Federal de S\u00e3o Carlos","ror":"https://ror.org/00qdc6m37","country_code":"BR","type":"education","lineage":["https://openalex.org/I177909021"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Marco Antonio de Lima","raw_affiliation_strings":["Laboratory of Clinical Exercise Physiology, Department of Physiological Sciences, Federal University of S\u00e3o Carlos, S\u00e3o Carlos 13565-905, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Clinical Exercise Physiology, Department of Physiological Sciences, Federal University of S\u00e3o Carlos, S\u00e3o Carlos 13565-905, Brazil","institution_ids":["https://openalex.org/I177909021"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103767624","display_name":"Jos\u00e9 Campanholi Neto","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I177909021","display_name":"Universidade Federal de S\u00e3o Carlos","ror":"https://ror.org/00qdc6m37","country_code":"BR","type":"education","lineage":["https://openalex.org/I177909021"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Jos\u00e9 Campanholi Neto","raw_affiliation_strings":["Department of Morphology and Pathology, Federal University of S\u00e3o Carlos, S\u00e3o Carlos 13565-905, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Morphology and Pathology, Federal University of S\u00e3o Carlos, S\u00e3o Carlos 13565-905, Brazil","institution_ids":["https://openalex.org/I177909021"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035076304","display_name":"Jonato Prestes","orcid":"https://orcid.org/0000-0003-0399-8817","observed_orcids":["https://orcid.org/0000-0003-0399-8817"]},"institutions":[{"id":"https://openalex.org/I24871856","display_name":"Universidade Cat\u00f3lica de Bras\u00edlia","ror":"https://ror.org/0058wy590","country_code":"BR","type":"education","lineage":["https://openalex.org/I24871856"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Jonato Prestes","raw_affiliation_strings":["Graduation Program on Physical Education, Catholic University of Bras\u00edlia, Bras\u00edlia 71966-700, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Graduation Program on Physical Education, Catholic University of Bras\u00edlia, Bras\u00edlia 71966-700, Brazil","institution_ids":["https://openalex.org/I24871856"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072747228","display_name":"James W. Navalta","orcid":"https://orcid.org/0000-0002-4445-7614","observed_orcids":["https://orcid.org/0000-0002-4445-7614"]},"institutions":[{"id":"https://openalex.org/I133999245","display_name":"University of Nevada, Las Vegas","ror":"https://ror.org/0406gha72","country_code":"US","type":"education","lineage":["https://openalex.org/I133999245"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"James Navalta","raw_affiliation_strings":["Department of Kinesiology and Nutrition Sciences, University of Nevada, Las Vegas, NV 89154, USA"],"raw_orcid":"https://orcid.org/0000-0002-4445-7614","affiliations":[{"raw_affiliation_string":"Department of Kinesiology and Nutrition Sciences, University of Nevada, Las Vegas, NV 89154, USA","institution_ids":["https://openalex.org/I133999245"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5044417810","display_name":"Guilherme Borges Pereira","orcid":"https://orcid.org/0000-0002-5295-6229","observed_orcids":["https://orcid.org/0000-0002-5295-6229"]},"institutions":[{"id":"https://openalex.org/I177909021","display_name":"Universidade Federal de S\u00e3o Carlos","ror":"https://ror.org/00qdc6m37","country_code":"BR","type":"education","lineage":["https://openalex.org/I177909021"]}],"countries":["BR"],"is_corresponding":true,"raw_author_name":"Guilherme Borges Pereira","raw_affiliation_strings":["Laboratory of Clinical Exercise Physiology, Department of Physiological Sciences, Federal University of S\u00e3o Carlos, S\u00e3o Carlos 13565-905, Brazil"],"raw_orcid":"https://orcid.org/0000-0002-5295-6229","affiliations":[{"raw_affiliation_string":"Laboratory of Clinical Exercise Physiology, Department of Physiological Sciences, Federal University of S\u00e3o Carlos, S\u00e3o Carlos 13565-905, Brazil","institution_ids":["https://openalex.org/I177909021"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5044417810"],"corresponding_institution_ids":["https://openalex.org/I177909021"],"apc_list":{"value":2600,"currency":"CHF","value_usd":3137},"apc_paid":{"value":2600,"currency":"CHF","value_usd":3137},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.02201766,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"16","issue":"1","first_page":"38","last_page":"38"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11368","display_name":"Long-Term Effects of COVID-19","score":0.8765000104904175,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11368","display_name":"Long-Term Effects of COVID-19","score":0.8765000104904175,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11209","display_name":"Cardiovascular and exercise physiology","score":0.1200999990105629,"subfield":{"id":"https://openalex.org/subfields/2707","display_name":"Complementary and alternative medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10745","display_name":"Heart Rate Variability and Autonomic Control","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/long-covid","display_name":"long COVID","score":0.9810000061988831},{"id":"https://openalex.org/keywords/maximal-exercise","display_name":"maximal exercise","score":0.6660000085830688},{"id":"https://openalex.org/keywords/hemodynamic-response","display_name":"hemodynamic response","score":0.7829999923706055},{"id":"https://openalex.org/keywords/autonomic-function","display_name":"autonomic function","score":0.8479999899864197},{"id":"https://openalex.org/keywords/heart-rate-variability","display_name":"heart rate variability","score":0.8199999928474426},{"id":"https://openalex.org/keywords/pulse-wave-velocity","display_name":"pulse wave velocity","score":0.7390000224113464},{"id":"https://openalex.org/keywords/vascular-resistance","display_name":"vascular resistance","score":0.7900000214576721},{"id":"https://openalex.org/keywords/blood-pressure","display_name":"blood pressure","score":0.5989999771118164},{"id":"https://openalex.org/keywords/sex-differences","display_name":"sex differences","score":0.5600000023841858},{"id":"https://openalex.org/keywords/post-exercise-recovery","display_name":"post-exercise recovery","score":0.7450000047683716},{"id":"https://openalex.org/keywords/ambulatory-blood-pressure","display_name":"ambulatory blood pressure","score":0.7379999756813049},{"id":"https://openalex.org/keywords/young-adults","display_name":"young adults","score":0.7269999980926514},{"id":"https://openalex.org/keywords/cardiopulmonary-exercise-testing","display_name":"cardiopulmonary exercise testing","score":0.8429999947547913},{"id":"https://openalex.org/keywords/circadian-rhythm-of-blood-pressure","display_name":"circadian blood pressure rhythm","score":0.6140000224113464},{"id":"https://openalex.org/keywords/exercise-intolerance","display_name":"exercise intolerance","score":0.4950000047683716},{"id":"https://openalex.org/keywords/fatigue","display_name":"fatigue","score":0.6110000014305115},{"id":"https://openalex.org/keywords/autonomic-dysfunction","display_name":"autonomic dysfunction","score":0.8009999990463257},{"id":"https://openalex.org/keywords/cardiac-output","display_name":"cardiac output","score":0.593999981880188},{"id":"https://openalex.org/keywords/heart-rate-recovery","display_name":"heart rate recovery","score":0.5979999899864197},{"id":"https://openalex.org/keywords/nocturnal-blood-pressure-decline","display_name":"nocturnal blood pressure dipping","score":0.5350000262260437}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.845300018787384},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.7616000175476074},{"id":"https://openalex.org/C2777953023","wikidata":"https://www.wikidata.org/wiki/Q1073121","display_name":"Heart rate","level":3,"score":0.7289999723434448},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.6668999791145325},{"id":"https://openalex.org/C205545832","wikidata":"https://www.wikidata.org/wiki/Q17156455","display_name":"Young adult","level":2,"score":0.5967000126838684},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5929999947547913},{"id":"https://openalex.org/C2778319312","wikidata":"https://www.wikidata.org/wiki/Q2118022","display_name":"Pulse wave velocity","level":3,"score":0.5604000091552734},{"id":"https://openalex.org/C149323552","wikidata":"https://www.wikidata.org/wiki/Q3090739","display_name":"Ambulatory blood pressure","level":3,"score":0.557699978351593},{"id":"https://openalex.org/C35785553","wikidata":"https://www.wikidata.org/wiki/Q756720","display_name":"Ambulatory","level":2,"score":0.5364999771118164},{"id":"https://openalex.org/C3008058167","wikidata":"https://www.wikidata.org/wiki/Q84263196","display_name":"Coronavirus disease 2019 (COVID-19)","level":4,"score":0.4952999949455261},{"id":"https://openalex.org/C71635504","wikidata":"https://www.wikidata.org/wiki/Q933954","display_name":"Heart rate variability","level":4,"score":0.49239999055862427},{"id":"https://openalex.org/C58245268","wikidata":"https://www.wikidata.org/wiki/Q456026","display_name":"Vascular resistance","level":3,"score":0.45590001344680786},{"id":"https://openalex.org/C57900726","wikidata":"https://www.wikidata.org/wiki/Q492905","display_name":"Diastole","level":3,"score":0.45350000262260437},{"id":"https://openalex.org/C46762472","wikidata":"https://www.wikidata.org/wiki/Q178648","display_name":"Peripheral","level":2,"score":0.44830000400543213},{"id":"https://openalex.org/C178853913","wikidata":"https://www.wikidata.org/wiki/Q1642137","display_name":"Hemodynamics","level":2,"score":0.4219000041484833},{"id":"https://openalex.org/C17140001","wikidata":"https://www.wikidata.org/wiki/Q1759415","display_name":"Pulse pressure","level":3,"score":0.4153999984264374},{"id":"https://openalex.org/C2994230362","wikidata":"https://www.wikidata.org/wiki/Q456026","display_name":"Peripheral resistance","level":4,"score":0.40290001034736633},{"id":"https://openalex.org/C139940330","wikidata":"https://www.wikidata.org/wiki/Q596579","display_name":"Cardiac output","level":3,"score":0.3995000123977661},{"id":"https://openalex.org/C31861589","wikidata":"https://www.wikidata.org/wiki/Q618068","display_name":"Cardiac index","level":4,"score":0.3776000142097473},{"id":"https://openalex.org/C2777372248","wikidata":"https://www.wikidata.org/wiki/Q171064","display_name":"Autonomic nervous system","level":4,"score":0.3668999969959259},{"id":"https://openalex.org/C2780167933","wikidata":"https://www.wikidata.org/wiki/Q1550652","display_name":"Pulse (music)","level":3,"score":0.3546999990940094},{"id":"https://openalex.org/C2780040984","wikidata":"https://www.wikidata.org/wiki/Q79785","display_name":"Electrocardiography","level":2,"score":0.34450000524520874},{"id":"https://openalex.org/C2911194756","wikidata":"https://www.wikidata.org/wiki/Q1073121","display_name":"RESTING HEART RATE","level":4,"score":0.28870001435279846},{"id":"https://openalex.org/C80461066","wikidata":"https://www.wikidata.org/wiki/Q1698533","display_name":"Stroke volume","level":4,"score":0.26840001344680786},{"id":"https://openalex.org/C3006700255","wikidata":"https://www.wikidata.org/wiki/Q81068910","display_name":"2019-20 coronavirus outbreak","level":3,"score":0.2671999931335449},{"id":"https://openalex.org/C2776452961","wikidata":"https://www.wikidata.org/wiki/Q1940733","display_name":"Mean arterial pressure","level":4,"score":0.26260000467300415},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.25209999084472656}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.3390/jpm16010038","doi":"https://doi.org/10.3390/jpm16010038","is_oa":true,"landing_page_url":"https://doi.org/10.3390/jpm16010038","pdf_url":"https://www.mdpi.com/2075-4426/16/1/38/pdf","source":{"id":"https://openalex.org/S2736780684","display_name":"Journal of Personalized Medicine","issn_l":"2075-4426","issn":["2075-4426"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","erih-plus","norway-1"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Personalized Medicine","raw_type":"journal-article"},{"id":"pmid:41590531","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/41590531","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of personalized medicine","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:12843395","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12843395/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"J Pers Med","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.3390/jpm16010038","doi":"https://doi.org/10.3390/jpm16010038","is_oa":true,"landing_page_url":"https://doi.org/10.3390/jpm16010038","pdf_url":"https://www.mdpi.com/2075-4426/16/1/38/pdf","source":{"id":"https://openalex.org/S2736780684","display_name":"Journal of Personalized Medicine","issn_l":"2075-4426","issn":["2075-4426"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","erih-plus","norway-1"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Personalized Medicine","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/3","score":0.44478926062583923,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[{"id":"https://openalex.org/G3068222038","display_name":null,"funder_award_id":"2024/08454-5","funder_id":"https://openalex.org/F4320320997","funder_display_name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo"},{"id":"https://openalex.org/G3933407216","display_name":null,"funder_award_id":"8888.824158/2023-00","funder_id":"https://openalex.org/F4320321091","funder_display_name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior"},{"id":"https://openalex.org/G5982417877","display_name":null,"funder_award_id":"2024/09199-9","funder_id":"https://openalex.org/F4320320997","funder_display_name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo"}],"funders":[{"id":"https://openalex.org/F4320320997","display_name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo","ror":"https://ror.org/02ddkpn78"},{"id":"https://openalex.org/F4320321091","display_name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","ror":"https://ror.org/00x0ma614"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7119018022.pdf","grobid_xml":"https://content.openalex.org/works/W7119018022.grobid-xml"},"referenced_works_count":47,"referenced_works":["https://openalex.org/W1660338335","https://openalex.org/W1992952012","https://openalex.org/W2060447849","https://openalex.org/W2074602210","https://openalex.org/W2087484885","https://openalex.org/W2089901353","https://openalex.org/W2091585671","https://openalex.org/W2098352519","https://openalex.org/W2116143368","https://openalex.org/W2117731623","https://openalex.org/W2118628174","https://openalex.org/W2131288011","https://openalex.org/W2318588083","https://openalex.org/W2346989408","https://openalex.org/W2399535671","https://openalex.org/W2790385199","https://openalex.org/W2917146357","https://openalex.org/W2982436757","https://openalex.org/W3005683316","https://openalex.org/W3038797657","https://openalex.org/W3107718970","https://openalex.org/W3136444061","https://openalex.org/W3136955306","https://openalex.org/W3174941847","https://openalex.org/W3184793398","https://openalex.org/W3186907009","https://openalex.org/W3197094088","https://openalex.org/W3212371437","https://openalex.org/W3213374156","https://openalex.org/W3216811094","https://openalex.org/W4224251103","https://openalex.org/W4225126498","https://openalex.org/W4225148367","https://openalex.org/W4283208508","https://openalex.org/W4286447836","https://openalex.org/W4304695132","https://openalex.org/W4311231072","https://openalex.org/W4367693476","https://openalex.org/W4379768915","https://openalex.org/W4380681559","https://openalex.org/W4386410307","https://openalex.org/W4387518756","https://openalex.org/W4399715569","https://openalex.org/W4400190292","https://openalex.org/W4401160614","https://openalex.org/W4408781982","https://openalex.org/W4413308991"],"related_works":[],"abstract_inverted_index":{"Background/Objectives:":[0],"Long":[1,57],"COVID":[2,58],"(LC)":[3],"has":[4],"been":[5],"linked":[6],"to":[7,20,32,42,185,297],"fatigue,":[8],"exercise":[9,48,321],"intolerance,":[10],"and":[11,36,40,55,84,102,112,125,137,155,158,183,207,241,270,286,290,320],"autonomic":[12],"dysfunction,":[13],"but":[14],"sex-stratified":[15,304],"data":[16],"on":[17],"cardiovascular":[18,305],"responses":[19,38,288],"maximal":[21,292],"exercise\u2014an":[22],"essential":[23],"component":[24],"of":[25],"personalized":[26,298],"medicine\u2014are":[27],"scarce.":[28],"This":[29],"study":[30],"aimed":[31],"examine":[33],"hemodynamic,":[34,284],"autonomic,":[35,285],"functional":[37],"during":[39,173,289],"up":[41],"24":[43,160],"h":[44,161],"after":[45,167,291],"a":[46],"cardiopulmonary":[47],"test":[49],"(CPET)":[50],"in":[51,178,312],"young":[52],"adults":[53,279],"with":[54,175,265,280],"without":[56,247],"(LC).":[59],"Methods:":[60],"In":[61],"this":[62,313],"cross-sectional":[63],"study,":[64],"we":[65],"assessed":[66,144],"38":[67],"physically":[68,277],"active":[69,278],"adults,":[70],"who":[71],"were":[72],"allocated":[73],"into":[74],"four":[75],"subgroups":[76],"stratified":[77],"by":[78,235,300],"clinical":[79,317],"condition":[80],"(LC":[81],"or":[82],"control)":[83],"biological":[85],"sex:":[86],"control\u2013female":[87],"(CON-F;":[88],"n":[89,94,99,105],"=":[90,95,100,106,215,222,229],"10),":[91,96,101],"LC\u2013female":[92],"(LC-F;":[93],"control\u2013male":[97],"(CON-M;":[98],"LC\u2013male":[103],"(LC-M;":[104],"8).":[107],"Outcomes":[108],"included":[109],"systolic":[110,267],"(SBP)":[111],"diastolic":[113],"blood":[114,163],"pressure":[115,164],"(DBP),":[116],"heart":[117,138],"rate":[118,139],"(HR),":[119],"cardiac":[120],"output":[121],"(CO),":[122],"total":[123],"(TPR)":[124],"peripheral":[126],"vascular":[127,287],"resistance":[128],"(PVR),":[129],"pulse":[130],"wave":[131],"velocity":[132],"(PWV),":[133],"augmentation":[134],"index":[135],"(AIx@75),":[136],"variability":[140],"(HF,":[141],"LF,":[142],"LF/HF),":[143],"at":[145,204],"rest,":[146],"peak":[147],"effort,":[148],"recovery":[149,194],"(1,":[150],"3,":[151,205],"5,":[152,206],"10,":[153],"30,":[154],"60":[156,236],"min),":[157],"through":[159],"ambulatory":[162],"monitoring":[165,260],"(ABPM)":[166],"CPET.":[168],"Results:":[169],"SBP":[170],"increase":[171],"appropriately":[172],"exercise,":[174],"higher":[176],"peaks":[177],"males":[179],"(p":[180],"<":[181],"0.01),":[182],"returned":[184],"baseline":[186],"within":[187],"5":[188],"min":[189,209],"across":[190],"all":[191,232],"groups.":[192],"HR":[193],"was":[195],"preserved;":[196],"however,":[197],"LC-F":[198],"showed":[199,252,282],"lower":[200],"values":[201],"than":[202],"CON-F":[203],"10":[208],"(126":[210],"vs.":[211,218,225],"144":[212],"bpm,":[213,220,227],"p":[214,221,228],"0.020;":[216,223],"119":[217],"136":[219],"94":[224],"109":[226],"0.011),":[230],"though":[231],"groups":[233],"normalized":[234],"min.":[237],"PWV,":[238],"AIx@75,":[239],"TPR":[240],"PVR":[242],"exhibited":[243],"expected":[244],"sex-related":[245],"patterns":[246],"LC-related":[248],"impairments.":[249],"HRV":[250],"indices":[251],"transient":[253],"post-exercise":[254],"shifts":[255],"(HF\u2193,":[256],"LF\u2191,":[257],"LF/HF\u2191).":[258],"Ambulatory":[259],"confirmed":[261],"preserved":[262,283],"circadian":[263],"modulation,":[264],"normal":[266],"dipping":[268],"(11\u201313%)":[269],"no":[271,308],"abnormal":[272],"nocturnal":[273],"patterns.":[274],"Conclusions:":[275],"Young":[276],"LC":[281],"exercise.":[293],"These":[294],"findings":[295],"contribute":[296],"medicine":[299],"showing":[301],"that":[302],"individualized,":[303],"assessments":[306],"reveal":[307],"clinically":[309],"relevant":[310],"impairments":[311],"population,":[314],"supporting":[315],"tailored":[316],"decision":[318],"making":[319],"prescription.":[322]},"counts_by_year":[],"updated_date":"2026-09-26T08:19:03.415552","created_date":"2026-01-08T00:00:00"}