{"id":"https://openalex.org/W7118288587","doi":"https://doi.org/10.1038/s41598-025-34501-6","title":"Age distribution of high-risk HPV infection and cervical lesions in an unvaccinated adult Brazilian population within an organized screening program","display_name":"Age distribution of high-risk HPV infection and cervical lesions in an unvaccinated adult Brazilian population within an organized screening program","publication_year":2026,"publication_date":"2026-01-07","ids":{"openalex":"https://openalex.org/W7118288587","doi":"https://doi.org/10.1038/s41598-025-34501-6","pmid":"https://pubmed.ncbi.nlm.nih.gov/41501235"},"language":"en","primary_location":{"id":"doi:10.1038/s41598-025-34501-6","doi":"https://doi.org/10.1038/s41598-025-34501-6","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41598-025-34501-6","pdf_url":"https://www.nature.com/articles/s41598-025-34501-6_reference.pdf","source":{"id":"https://openalex.org/S196734849","display_name":"Scientific Reports","issn_l":"2045-2322","issn":["2045-2322"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scientific Reports","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.nature.com/articles/s41598-025-34501-6_reference.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5089716697","display_name":"Rafaella Moraes Rego de Sousa Coelho","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I181391015","display_name":"Universidade Estadual de Campinas (UNICAMP)","ror":"https://ror.org/04wffgt70","country_code":"BR","type":"education","lineage":["https://openalex.org/I181391015"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Rafaella Moraes Rego","raw_affiliation_strings":["Department of Obstetrics and Gynecology, University of Campinas (UNICAMP), Campinas, SP, 13098-340, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics and Gynecology, University of Campinas (UNICAMP), Campinas, SP, 13098-340, Brazil","institution_ids":["https://openalex.org/I181391015"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008907993","display_name":"Diama Bhadra Vale","orcid":"https://orcid.org/0000-0003-2423-0225","observed_orcids":["https://orcid.org/0000-0003-2423-0225"]},"institutions":[{"id":"https://openalex.org/I181391015","display_name":"Universidade Estadual de Campinas (UNICAMP)","ror":"https://ror.org/04wffgt70","country_code":"BR","type":"education","lineage":["https://openalex.org/I181391015"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Diama Bhadra Vale","raw_affiliation_strings":["Department of Obstetrics and Gynecology, University of Campinas (UNICAMP), Campinas, SP, 13098-340, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics and Gynecology, University of Campinas (UNICAMP), Campinas, SP, 13098-340, Brazil","institution_ids":["https://openalex.org/I181391015"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009341988","display_name":"Cirbia Silva Campos","orcid":"https://orcid.org/0000-0002-8742-5874","observed_orcids":["https://orcid.org/0000-0002-8742-5874"]},"institutions":[{"id":"https://openalex.org/I181391015","display_name":"Universidade Estadual de Campinas (UNICAMP)","ror":"https://ror.org/04wffgt70","country_code":"BR","type":"education","lineage":["https://openalex.org/I181391015"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Cirbia Silva Campos","raw_affiliation_strings":["Department of Obstetrics and Gynecology, University of Campinas (UNICAMP), Campinas, SP, 13098-340, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics and Gynecology, University of Campinas (UNICAMP), Campinas, SP, 13098-340, Brazil","institution_ids":["https://openalex.org/I181391015"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5122046105","display_name":"Leandro Vasconcelos","orcid":"https://orcid.org/0000-0002-0299-8172","observed_orcids":["https://orcid.org/0000-0002-0299-8172"]},"institutions":[{"id":"https://openalex.org/I181391015","display_name":"Universidade Estadual de Campinas (UNICAMP)","ror":"https://ror.org/04wffgt70","country_code":"BR","type":"education","lineage":["https://openalex.org/I181391015"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Leandro Vasconcelos","raw_affiliation_strings":["Department of Obstetrics and Gynecology, University of Campinas (UNICAMP), Campinas, SP, 13098-340, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics and Gynecology, University of Campinas (UNICAMP), Campinas, SP, 13098-340, Brazil","institution_ids":["https://openalex.org/I181391015"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5153310529","display_name":"Eduardo Campos","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I181391015","display_name":"Universidade Estadual de Campinas (UNICAMP)","ror":"https://ror.org/04wffgt70","country_code":"BR","type":"education","lineage":["https://openalex.org/I181391015"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Eduardo Campos","raw_affiliation_strings":["Department of Obstetrics and Gynecology, University of Campinas (UNICAMP), Campinas, SP, 13098-340, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics and Gynecology, University of Campinas (UNICAMP), Campinas, SP, 13098-340, Brazil","institution_ids":["https://openalex.org/I181391015"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040395927","display_name":"Helena da Cunha Lopes de Lima","orcid":"https://orcid.org/0000-0001-9286-1817","observed_orcids":["https://orcid.org/0000-0001-9286-1817"]},"institutions":[{"id":"https://openalex.org/I181391015","display_name":"Universidade Estadual de Campinas (UNICAMP)","ror":"https://ror.org/04wffgt70","country_code":"BR","type":"education","lineage":["https://openalex.org/I181391015"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Helena Cunha Lopes Lima","raw_affiliation_strings":["Department of Obstetrics and Gynecology, University of Campinas (UNICAMP), Campinas, SP, 13098-340, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics and Gynecology, University of Campinas (UNICAMP), Campinas, SP, 13098-340, Brazil","institution_ids":["https://openalex.org/I181391015"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053587316","display_name":"Michelle Garcia Discacciati","orcid":"https://orcid.org/0000-0003-3660-3826","observed_orcids":["https://orcid.org/0000-0003-3660-3826"]},"institutions":[{"id":"https://openalex.org/I181391015","display_name":"Universidade Estadual de Campinas (UNICAMP)","ror":"https://ror.org/04wffgt70","country_code":"BR","type":"education","lineage":["https://openalex.org/I181391015"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Michelle Garcia Discacciati","raw_affiliation_strings":["Department of Obstetrics and Gynecology, University of Campinas (UNICAMP), Campinas, SP, 13098-340, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics and Gynecology, University of Campinas (UNICAMP), Campinas, SP, 13098-340, Brazil","institution_ids":["https://openalex.org/I181391015"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084933228","display_name":"Lu\u00edz Carlos Zeferino","orcid":"https://orcid.org/0000-0002-5495-0971","observed_orcids":["https://orcid.org/0000-0002-5495-0971"]},"institutions":[{"id":"https://openalex.org/I181391015","display_name":"Universidade Estadual de Campinas (UNICAMP)","ror":"https://ror.org/04wffgt70","country_code":"BR","type":"education","lineage":["https://openalex.org/I181391015"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Luiz Carlos Zeferino","raw_affiliation_strings":["Department of Obstetrics and Gynecology, University of Campinas (UNICAMP), Campinas, SP, 13098-340, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics and Gynecology, University of Campinas (UNICAMP), Campinas, SP, 13098-340, Brazil","institution_ids":["https://openalex.org/I181391015"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5071753660","display_name":"J\u00falio C\u00e9sar Teixeira","orcid":"https://orcid.org/0000-0002-0979-376X","observed_orcids":["https://orcid.org/0000-0002-0979-376X"]},"institutions":[{"id":"https://openalex.org/I181391015","display_name":"Universidade Estadual de Campinas (UNICAMP)","ror":"https://ror.org/04wffgt70","country_code":"BR","type":"education","lineage":["https://openalex.org/I181391015"]}],"countries":["BR"],"is_corresponding":true,"raw_author_name":"Julio Cesar Teixeira","raw_affiliation_strings":["Department of Obstetrics and Gynecology, University of Campinas (UNICAMP), Campinas, SP, 13098-340, Brazil. juliotex@unicamp.br"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics and Gynecology, University of Campinas (UNICAMP), Campinas, SP, 13098-340, Brazil. juliotex@unicamp.br","institution_ids":["https://openalex.org/I181391015"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5071753660"],"corresponding_institution_ids":["https://openalex.org/I181391015"],"apc_list":{"value":2690,"currency":"USD","value_usd":2690},"apc_paid":{"value":2690,"currency":"USD","value_usd":2690},"fwci":21.7379,"has_fulltext":true,"cited_by_count":5,"citation_normalized_percentile":{"value":0.99282842,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":98,"max":99},"biblio":{"volume":"16","issue":"1","first_page":"4453","last_page":"4453"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10146","display_name":"Cervical Cancer and HPV Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10146","display_name":"Cervical Cancer and HPV Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13544","display_name":"Women's cancer prevention and management","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10428","display_name":"Reproductive tract infections research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/high-risk-hpv","display_name":"high-risk HPV","score":0.9139999747276306},{"id":"https://openalex.org/keywords/hpv-prevalence","display_name":"HPV prevalence","score":0.6349999904632568},{"id":"https://openalex.org/keywords/age-distribution","display_name":"age distribution","score":0.8080000281333923},{"id":"https://openalex.org/keywords/cervical-intraepithelial-neoplasia","display_name":"cervical intraepithelial neoplasia","score":0.9070000052452087},{"id":"https://openalex.org/keywords/cervical-cancer","display_name":"cervical cancer","score":0.7630000114440918},{"id":"https://openalex.org/keywords/hpv-testing","display_name":"HPV testing","score":0.7720000147819519},{"id":"https://openalex.org/keywords/unvaccinated-women","display_name":"unvaccinated women","score":0.8529999852180481},{"id":"https://openalex.org/keywords/hpv-16","display_name":"HPV16","score":0.8759999871253967},{"id":"https://openalex.org/keywords/hpv-18","display_name":"HPV 18","score":0.9909999966621399},{"id":"https://openalex.org/keywords/brazil","display_name":"Brazil","score":0.515999972820282}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8346999883651733},{"id":"https://openalex.org/C2778580637","wikidata":"https://www.wikidata.org/wiki/Q184627","display_name":"HPV infection","level":4,"score":0.6815999746322632},{"id":"https://openalex.org/C2778220009","wikidata":"https://www.wikidata.org/wiki/Q160105","display_name":"Cervical cancer","level":3,"score":0.6349999904632568},{"id":"https://openalex.org/C2994532551","wikidata":"https://www.wikidata.org/wiki/Q184627","display_name":"Human papillomavirus","level":2,"score":0.5902000069618225},{"id":"https://openalex.org/C2993522905","wikidata":"https://www.wikidata.org/wiki/Q5065348","display_name":"Cervical cancer screening","level":4,"score":0.5120000243186951},{"id":"https://openalex.org/C205545832","wikidata":"https://www.wikidata.org/wiki/Q17156455","display_name":"Young adult","level":2,"score":0.5056999921798706},{"id":"https://openalex.org/C2986834420","wikidata":"https://www.wikidata.org/wiki/Q5932254","display_name":"Age groups","level":2,"score":0.49300000071525574},{"id":"https://openalex.org/C2780647465","wikidata":"https://www.wikidata.org/wiki/Q5065348","display_name":"Cervical screening","level":4,"score":0.48890000581741333},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.47279998660087585},{"id":"https://openalex.org/C29456083","wikidata":"https://www.wikidata.org/wiki/Q1221899","display_name":"Gynecology","level":1,"score":0.45019999146461487},{"id":"https://openalex.org/C22070199","wikidata":"https://www.wikidata.org/wiki/Q192995","display_name":"Vaccination","level":2,"score":0.4348999857902527},{"id":"https://openalex.org/C2776270601","wikidata":"https://www.wikidata.org/wiki/Q9055203","display_name":"Papillomaviridae","level":4,"score":0.35339999198913574},{"id":"https://openalex.org/C149923435","wikidata":"https://www.wikidata.org/wiki/Q37732","display_name":"Demography","level":1,"score":0.3402000069618225},{"id":"https://openalex.org/C131872663","wikidata":"https://www.wikidata.org/wiki/Q5284418","display_name":"Obstetrics","level":1,"score":0.3400000035762787},{"id":"https://openalex.org/C107130276","wikidata":"https://www.wikidata.org/wiki/Q133805","display_name":"Epidemiology","level":2,"score":0.33959999680519104},{"id":"https://openalex.org/C167135981","wikidata":"https://www.wikidata.org/wiki/Q2146302","display_name":"Retrospective cohort study","level":2,"score":0.31459999084472656},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.30230000615119934},{"id":"https://openalex.org/C110121322","wikidata":"https://www.wikidata.org/wiki/Q865811","display_name":"Distribution (mathematics)","level":2,"score":0.28940001130104065},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.2768999934196472},{"id":"https://openalex.org/C142052008","wikidata":"https://www.wikidata.org/wiki/Q954027","display_name":"Cross-sectional study","level":2,"score":0.25780001282691956},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.25609999895095825},{"id":"https://openalex.org/C2779473830","wikidata":"https://www.wikidata.org/wiki/Q1540899","display_name":"MEDLINE","level":2,"score":0.2506999969482422},{"id":"https://openalex.org/C48718317","wikidata":"https://www.wikidata.org/wiki/Q4691855","display_name":"Age adjustment","level":3,"score":0.25040000677108765}],"mesh":[{"descriptor_ui":"D000094302","descriptor_name":"Human Papillomavirus Viruses","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D000094302","descriptor_name":"Human Papillomavirus Viruses","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":true},{"descriptor_ui":"D000096967","descriptor_name":"Unvaccinated Persons","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001938","descriptor_name":"Brazil","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D002578","descriptor_name":"Uterine Cervical Dysplasia","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D002578","descriptor_name":"Uterine Cervical Dysplasia","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":true},{"descriptor_ui":"D002583","descriptor_name":"Uterine Cervical Neoplasms","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D002583","descriptor_name":"Uterine Cervical Neoplasms","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D002583","descriptor_name":"Uterine Cervical Neoplasms","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008403","descriptor_name":"Mass Screening","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015995","descriptor_name":"Prevalence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017677","descriptor_name":"Age Distribution","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030361","descriptor_name":"Papillomavirus Infections","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D030361","descriptor_name":"Papillomavirus Infections","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D030361","descriptor_name":"Papillomavirus Infections","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":true},{"descriptor_ui":"D055088","descriptor_name":"Early Detection of Cancer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1038/s41598-025-34501-6","doi":"https://doi.org/10.1038/s41598-025-34501-6","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41598-025-34501-6","pdf_url":"https://www.nature.com/articles/s41598-025-34501-6_reference.pdf","source":{"id":"https://openalex.org/S196734849","display_name":"Scientific Reports","issn_l":"2045-2322","issn":["2045-2322"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scientific Reports","raw_type":"journal-article"},{"id":"pmid:41501235","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/41501235","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scientific reports","raw_type":"Journal Article"},{"id":"pmh:oai:europepmc.org:11672372","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/12864863","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:39e8108b39a64421bb761f3702871ca7","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/39e8108b39a64421bb761f3702871ca7","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Scientific Reports, Vol 16, Iss 1, Pp 1-8 (2026)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1038/s41598-025-34501-6","doi":"https://doi.org/10.1038/s41598-025-34501-6","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41598-025-34501-6","pdf_url":"https://www.nature.com/articles/s41598-025-34501-6_reference.pdf","source":{"id":"https://openalex.org/S196734849","display_name":"Scientific Reports","issn_l":"2045-2322","issn":["2045-2322"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scientific Reports","raw_type":"journal-article"},"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[{"score":0.6544026732444763,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[{"id":"https://openalex.org/G2823776494","display_name":null,"funder_award_id":"88887","funder_id":"https://openalex.org/F4320321091","funder_display_name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior"},{"id":"https://openalex.org/G6191138830","display_name":null,"funder_award_id":"88887","funder_id":"https://openalex.org/F4320320997","funder_display_name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo"}],"funders":[{"id":"https://openalex.org/F4320320997","display_name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo","ror":"https://ror.org/02ddkpn78"},{"id":"https://openalex.org/F4320321091","display_name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","ror":"https://ror.org/00x0ma614"},{"id":"https://openalex.org/F4320337368","display_name":"Division of Graduate Education","ror":"https://ror.org/00whkrf32"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7118288587.pdf","grobid_xml":"https://content.openalex.org/works/W7118288587.grobid-xml"},"referenced_works_count":25,"referenced_works":["https://openalex.org/W1979863043","https://openalex.org/W2003194103","https://openalex.org/W2008958654","https://openalex.org/W2082805292","https://openalex.org/W2103680668","https://openalex.org/W2149866054","https://openalex.org/W2163036162","https://openalex.org/W2790356598","https://openalex.org/W2809460173","https://openalex.org/W2982431486","https://openalex.org/W3007949596","https://openalex.org/W3011030403","https://openalex.org/W3017554463","https://openalex.org/W3034077642","https://openalex.org/W3157185707","https://openalex.org/W3160984339","https://openalex.org/W4213107599","https://openalex.org/W4360609339","https://openalex.org/W4383340573","https://openalex.org/W4387498138","https://openalex.org/W4395455420","https://openalex.org/W4402258899","https://openalex.org/W4405980941","https://openalex.org/W4408563916","https://openalex.org/W4410953414"],"related_works":[],"abstract_inverted_index":{"High-risk":[0],"human":[1],"papillomavirus":[2],"(hr-HPV)":[3],"persistent":[4,173],"infection":[5,34],"is":[6],"the":[7,30,46,51,160,167],"necessary":[8],"cause":[9],"of":[10,32,50,105,162,175,196,198],"cervical":[11,36,122],"cancer,":[12],"yet":[13],"age-specific":[14],"prevalence":[15,64],"patterns":[16],"in":[17,24,58,100],"unvaccinated":[18],"adult":[19],"women":[20,40],"remain":[21],"insufficiently":[22],"characterized":[23],"Brazil.":[25],"This":[26],"population-based":[27],"study":[28],"describes":[29],"distribution":[31],"hr-HPV":[33,63,96,114,176,204],"and":[35,82,93,103,137,177,183],"lesions":[37,179],"among":[38],"20,398":[39],"aged":[41],"25\u201364":[42],"years":[43,80,89,145],"screened":[44],"during":[45],"first":[47,76],"screening":[48,199],"round":[49],"PREVENTIVO":[52],"organized":[53],"program":[54],"using":[55],"HPV-DNA":[56],"testing":[57],"Indaiatuba,":[59],"Brazil":[60],"(2017\u20132022).":[61],"Overall":[62],"was":[65],"12.8%":[66],"(95%":[67],"CI:":[68],"12.4\u201313.1),":[69],"with":[70,153],"a":[71,75,83,139,172,202],"bimodal":[72],"age":[73,157,208],"pattern:":[74],"peak":[77,86,142],"at":[78,87,143,150,180],"25\u201326":[79],"(26%)":[81],"smaller":[84],"second":[85],"55\u201356":[88],"(11.2%).":[90],"HPV16,":[91],"HPV18,":[92],"12":[94],"other":[95],"types":[97],"were":[98],"detected":[99],"2.63%,":[101],"1.01%,":[102],"10.72%":[104],"women,":[106,116],"respectively,":[107],"all":[108],"showing":[109],"significant":[110],"age-related":[111],"declines.":[112],"Among":[113],"positive":[115],"12.4%":[117],"had":[118],"CIN2+,":[119],"including":[120,201],"29":[121],"cancers.":[123],"CIN2":[124],"+":[125],"rates":[126],"ranged":[127],"from":[128],"11":[129],"to":[130],"17%":[131],"between":[132],"ages":[133,182],"25\u201349,":[134],"decreased":[135],"after,":[136],"showed":[138],"late":[140],"HSIL":[141],"61":[144],"(8.2%).":[146],"Cervical":[147],"cancer":[148],"peaked":[149],"45\u201346":[151],"years,":[152],"no":[154],"cases":[155],"after":[156],"55,":[158],"reflecting":[159],"impact":[161],"early":[163],"precursor":[164],"detection":[165],"within":[166],"program.":[168],"These":[169],"findings":[170],"demonstrate":[171],"burden":[174],"high-grade":[178],"older":[181],"provide":[184],"essential":[185],"baseline":[186],"data":[187],"for":[188],"monitoring":[189],"vaccination":[190],"impact.":[191],"They":[192],"also":[193],"support":[194],"consideration":[195],"extended":[197],"strategies,":[200],"potential":[203],"\u201cexit":[205],"test\u201d":[206],"beyond":[207],"64.":[209]},"counts_by_year":[{"year":2026,"cited_by_count":5}],"updated_date":"2026-10-12T09:40:04.860316","created_date":"2026-01-08T00:00:00"}