{"id":"https://openalex.org/W7116846524","doi":"https://doi.org/10.13294/j.aps.2025.0097","title":"CXCL11 impairs the function of regulatory T cells in lupus patients.","display_name":"CXCL11 impairs the function of regulatory T cells in lupus patients.","publication_year":2025,"publication_date":"2025-12-25","ids":{"openalex":"https://openalex.org/W7116846524","doi":"https://doi.org/10.13294/j.aps.2025.0097","pmid":"https://pubmed.ncbi.nlm.nih.gov/41423983"},"language":"en","primary_location":{"id":"pmid:41423983","doi":"https://doi.org/10.13294/j.aps.2025.0097","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/41423983","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sheng li xue bao : [Acta physiologica Sinica]","raw_type":"Journal Article"},"volume":null,"type":"article","indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5062400632","display_name":"Peng\u2010Yu Chen","orcid":"https://orcid.org/0000-0002-1041-4130","observed_orcids":["https://orcid.org/0000-0002-1041-4130"]},"institutions":[{"id":"https://openalex.org/I199305430","display_name":"Nantong University","ror":"https://ror.org/02afcvw97","country_code":"CN","type":"education","lineage":["https://openalex.org/I199305430"]},{"id":"https://openalex.org/I4210086801","display_name":"Affiliated Hospital of Nantong University","ror":"https://ror.org/001rahr89","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210086801"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Peng-Yu Chen","raw_affiliation_strings":["Department of Rheumatology, Affiliated Hospital of Nantong University, Nantong 226001, China","Nantong University, Nantong 226001, China","Research Center of Clinical Medicine, Affiliated Hospital of Nantong University, Nantong 226001, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Rheumatology, Affiliated Hospital of Nantong University, Nantong 226001, China","institution_ids":["https://openalex.org/I4210086801"]},{"raw_affiliation_string":"Nantong University, Nantong 226001, China","institution_ids":["https://openalex.org/I199305430"]},{"raw_affiliation_string":"Research Center of Clinical Medicine, Affiliated Hospital of Nantong University, Nantong 226001, China","institution_ids":["https://openalex.org/I4210086801"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003414196","display_name":"Hua Bei Guo","orcid":"https://orcid.org/0000-0002-3345-8005","observed_orcids":["https://orcid.org/0000-0002-3345-8005"]},"institutions":[{"id":"https://openalex.org/I4210086801","display_name":"Affiliated Hospital of Nantong University","ror":"https://ror.org/001rahr89","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210086801"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hua Guo","raw_affiliation_strings":["Department of Rheumatology, Affiliated Hospital of Nantong University, Nantong 226001, China","Research Center of Clinical Medicine, Affiliated Hospital of Nantong University, Nantong 226001, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Rheumatology, Affiliated Hospital of Nantong University, Nantong 226001, China","institution_ids":["https://openalex.org/I4210086801"]},{"raw_affiliation_string":"Research Center of Clinical Medicine, Affiliated Hospital of Nantong University, Nantong 226001, China","institution_ids":["https://openalex.org/I4210086801"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5121104887","display_name":"Yu-Nan Wang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I199305430","display_name":"Nantong University","ror":"https://ror.org/02afcvw97","country_code":"CN","type":"education","lineage":["https://openalex.org/I199305430"]},{"id":"https://openalex.org/I4210086801","display_name":"Affiliated Hospital of Nantong University","ror":"https://ror.org/001rahr89","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210086801"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yu-Nan Wang","raw_affiliation_strings":["Department of Rheumatology, Affiliated Hospital of Nantong University, Nantong 226001, China","Nantong University, Nantong 226001, China","Research Center of Clinical Medicine, Affiliated Hospital of Nantong University, Nantong 226001, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Rheumatology, Affiliated Hospital of Nantong University, Nantong 226001, China","institution_ids":["https://openalex.org/I4210086801"]},{"raw_affiliation_string":"Nantong University, Nantong 226001, China","institution_ids":["https://openalex.org/I199305430"]},{"raw_affiliation_string":"Research Center of Clinical Medicine, Affiliated Hospital of Nantong University, Nantong 226001, China","institution_ids":["https://openalex.org/I4210086801"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5121119705","display_name":"Hang Kang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I199305430","display_name":"Nantong University","ror":"https://ror.org/02afcvw97","country_code":"CN","type":"education","lineage":["https://openalex.org/I199305430"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hang Kang","raw_affiliation_strings":["Nantong University, Nantong 226001, China","Institute of Reproductive Medicine, Nantong University, Nantong 226001, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Nantong University, Nantong 226001, China","institution_ids":["https://openalex.org/I199305430"]},{"raw_affiliation_string":"Institute of Reproductive Medicine, Nantong University, Nantong 226001, China","institution_ids":["https://openalex.org/I199305430"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5121107443","display_name":"Neng-Jie Yang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I199305430","display_name":"Nantong University","ror":"https://ror.org/02afcvw97","country_code":"CN","type":"education","lineage":["https://openalex.org/I199305430"]},{"id":"https://openalex.org/I4210086801","display_name":"Affiliated Hospital of Nantong University","ror":"https://ror.org/001rahr89","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210086801"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Neng-Jie Yang","raw_affiliation_strings":["Department of Rheumatology, Affiliated Hospital of Nantong University, Nantong 226001, China","Nantong University, Nantong 226001, China","Research Center of Clinical Medicine, Affiliated Hospital of Nantong University, Nantong 226001, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Rheumatology, Affiliated Hospital of Nantong University, Nantong 226001, China","institution_ids":["https://openalex.org/I4210086801"]},{"raw_affiliation_string":"Nantong University, Nantong 226001, China","institution_ids":["https://openalex.org/I199305430"]},{"raw_affiliation_string":"Research Center of Clinical Medicine, Affiliated Hospital of Nantong University, Nantong 226001, China","institution_ids":["https://openalex.org/I4210086801"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5121045818","display_name":"Yue-Xiao Dai","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I191996457","display_name":"Dalian Medical University","ror":"https://ror.org/04c8eg608","country_code":"CN","type":"education","lineage":["https://openalex.org/I191996457"]},{"id":"https://openalex.org/I4210086801","display_name":"Affiliated Hospital of Nantong University","ror":"https://ror.org/001rahr89","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210086801"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yue-Xiao Dai","raw_affiliation_strings":["Department of Rheumatology, Affiliated Hospital of Nantong University, Nantong 226001, China","Research Center of Clinical Medicine, Affiliated Hospital of Nantong University, Nantong 226001, China","Dalian Medical University, Dalian 116000, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Rheumatology, Affiliated Hospital of Nantong University, Nantong 226001, China","institution_ids":["https://openalex.org/I4210086801"]},{"raw_affiliation_string":"Research Center of Clinical Medicine, Affiliated Hospital of Nantong University, Nantong 226001, China","institution_ids":["https://openalex.org/I4210086801"]},{"raw_affiliation_string":"Dalian Medical University, Dalian 116000, China","institution_ids":["https://openalex.org/I191996457"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076600025","display_name":"Zhifeng Gu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I199305430","display_name":"Nantong University","ror":"https://ror.org/02afcvw97","country_code":"CN","type":"education","lineage":["https://openalex.org/I199305430"]},{"id":"https://openalex.org/I4210086801","display_name":"Affiliated Hospital of Nantong University","ror":"https://ror.org/001rahr89","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210086801"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhi-Feng Gu","raw_affiliation_strings":["Department of Rheumatology, Affiliated Hospital of Nantong University, Nantong 226001, China","Nantong University, Nantong 226001, China","Research Center of Clinical Medicine, Affiliated Hospital of Nantong University, Nantong 226001, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Rheumatology, Affiliated Hospital of Nantong University, Nantong 226001, China","institution_ids":["https://openalex.org/I4210086801"]},{"raw_affiliation_string":"Nantong University, Nantong 226001, China","institution_ids":["https://openalex.org/I199305430"]},{"raw_affiliation_string":"Research Center of Clinical Medicine, Affiliated Hospital of Nantong University, Nantong 226001, China","institution_ids":["https://openalex.org/I4210086801"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5121104732","display_name":"Yun-Fei Xia","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I199305430","display_name":"Nantong University","ror":"https://ror.org/02afcvw97","country_code":"CN","type":"education","lineage":["https://openalex.org/I199305430"]},{"id":"https://openalex.org/I4210086801","display_name":"Affiliated Hospital of Nantong University","ror":"https://ror.org/001rahr89","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210086801"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yun-Fei Xia","raw_affiliation_strings":["Department of Rheumatology, Affiliated Hospital of Nantong University, Nantong 226001, China","Nantong University, Nantong 226001, China","Research Center of Clinical Medicine, Affiliated Hospital of Nantong University, Nantong 226001, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Rheumatology, Affiliated Hospital of Nantong University, Nantong 226001, China","institution_ids":["https://openalex.org/I4210086801"]},{"raw_affiliation_string":"Nantong University, Nantong 226001, China","institution_ids":["https://openalex.org/I199305430"]},{"raw_affiliation_string":"Research Center of Clinical Medicine, Affiliated Hospital of Nantong University, Nantong 226001, China","institution_ids":["https://openalex.org/I4210086801"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.54642521,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"77","issue":"6","first_page":"1133","last_page":"1147"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10308","display_name":"Systemic Lupus Erythematosus Research","score":0.9613999724388123,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10308","display_name":"Systemic Lupus Erythematosus Research","score":0.9613999724388123,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":0.0364999994635582,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13026","display_name":"Natural Compounds in Disease Treatment","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2707","display_name":"Complementary and alternative medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cxcl11","display_name":"CXCL11","score":1.0},{"id":"https://openalex.org/keywords/regulatory-t-cells","display_name":"regulatory T cells","score":0.9959999918937683},{"id":"https://openalex.org/keywords/systemic-lupus-erythematosus","display_name":"systemic lupus erythematosus","score":0.9980000257492065},{"id":"https://openalex.org/keywords/treg-differentiation","display_name":"Treg differentiation","score":0.8109999895095825},{"id":"https://openalex.org/keywords/disease-severity","display_name":"disease severity","score":0.7480000257492065},{"id":"https://openalex.org/keywords/plasma-chemokine-levels","display_name":"plasma chemokine levels","score":0.7279999852180481},{"id":"https://openalex.org/keywords/immunosuppression","display_name":"immunosuppression","score":0.746999979019165},{"id":"https://openalex.org/keywords/autoimmunity","display_name":"autoimmunity","score":0.7390000224113464}],"concepts":[{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.7052000164985657},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.6234999895095825},{"id":"https://openalex.org/C2776912625","wikidata":"https://www.wikidata.org/wiki/Q1485","display_name":"Systemic lupus erythematosus","level":3,"score":0.5680999755859375},{"id":"https://openalex.org/C2776090121","wikidata":"https://www.wikidata.org/wiki/Q193529","display_name":"T cell","level":3,"score":0.4724999964237213},{"id":"https://openalex.org/C2779075594","wikidata":"https://www.wikidata.org/wiki/Q8084905","display_name":"Autoimmune disease","level":3,"score":0.4359999895095825},{"id":"https://openalex.org/C2775915377","wikidata":"https://www.wikidata.org/wiki/Q188297","display_name":"Lupus erythematosus","level":3,"score":0.424699991941452},{"id":"https://openalex.org/C13373296","wikidata":"https://www.wikidata.org/wiki/Q421866","display_name":"Chemokine","level":3,"score":0.4235000014305115},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4194999933242798},{"id":"https://openalex.org/C2778690821","wikidata":"https://www.wikidata.org/wiki/Q212354","display_name":"Cytokine","level":2,"score":0.4081000089645386},{"id":"https://openalex.org/C13425408","wikidata":"https://www.wikidata.org/wiki/Q5014882","display_name":"CXCL11","level":5,"score":0.37119999527931213},{"id":"https://openalex.org/C62478195","wikidata":"https://www.wikidata.org/wiki/Q828130","display_name":"Signal transduction","level":2,"score":0.3531000018119812},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.35260000824928284},{"id":"https://openalex.org/C553184892","wikidata":"https://www.wikidata.org/wiki/Q1141429","display_name":"Flow cytometry","level":2,"score":0.35109999775886536},{"id":"https://openalex.org/C2780130043","wikidata":"https://www.wikidata.org/wiki/Q192360","display_name":"Autoimmunity","level":3,"score":0.34940001368522644},{"id":"https://openalex.org/C127716648","wikidata":"https://www.wikidata.org/wiki/Q104053","display_name":"Phenotype","level":3,"score":0.3215999901294708},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.31929999589920044},{"id":"https://openalex.org/C14036430","wikidata":"https://www.wikidata.org/wiki/Q3736076","display_name":"Function (biology)","level":2,"score":0.31790000200271606},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.3131999969482422},{"id":"https://openalex.org/C2778296632","wikidata":"https://www.wikidata.org/wiki/Q1550619","display_name":"Regulatory T cell","level":5,"score":0.2766000032424927},{"id":"https://openalex.org/C2777702733","wikidata":"https://www.wikidata.org/wiki/Q1356761","display_name":"Immune tolerance","level":3,"score":0.2743000090122223},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.266400009393692},{"id":"https://openalex.org/C17991360","wikidata":"https://www.wikidata.org/wiki/Q21173843","display_name":"Tumor necrosis factor alpha","level":2,"score":0.25589999556541443},{"id":"https://openalex.org/C101666144","wikidata":"https://www.wikidata.org/wiki/Q2587862","display_name":"CCL2","level":4,"score":0.2547999918460846},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.2526000142097473},{"id":"https://openalex.org/C148125776","wikidata":"https://www.wikidata.org/wiki/Q1622348","display_name":"CD28","level":4,"score":0.2513999938964844}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008180","descriptor_name":"Lupus Erythematosus, Systemic","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D008180","descriptor_name":"Lupus Erythematosus, Systemic","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D008180","descriptor_name":"Lupus Erythematosus, Systemic","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D008180","descriptor_name":"Lupus Erythematosus, Systemic","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D050378","descriptor_name":"T-Lymphocytes, Regulatory","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D050378","descriptor_name":"T-Lymphocytes, Regulatory","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D054371","descriptor_name":"Chemokine CXCL11","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D054371","descriptor_name":"Chemokine CXCL11","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D054371","descriptor_name":"Chemokine CXCL11","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D054371","descriptor_name":"Chemokine CXCL11","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":1,"locations":[{"id":"pmid:41423983","doi":"https://doi.org/10.13294/j.aps.2025.0097","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/41423983","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sheng li xue bao : [Acta physiologica Sinica]","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9940000176429749,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[{"score":0.7140882611274719,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":[],"abstract_inverted_index":{"Treg":[0,16,31,49],"cells":[1],"decreased.":[2],"Plasma":[3],"CXCL11":[4,11,25,43],"levels":[5],"were":[6],"elevated":[7],"in":[8,40],"lupus":[9],"patients.":[10],"expression":[12],"inversely":[13],"correlated":[14,21],"with":[15,22],"cell":[17,32],"proportions":[18],"and":[19,29],"positively":[20],"disease":[23],"severity.":[24],"impaired":[26],"immune":[27],"function":[28],"inhibited":[30],"differentiation.":[33],"We":[34],"present":[35],"a":[36],"novel":[37],"pathological":[38],"pathway":[39],"SLE,":[41],"wherein":[42],"impedes":[44],"the":[45],"immunosuppressive":[46],"functions":[47],"of":[48],"cells.":[50]},"counts_by_year":[],"updated_date":"2026-10-12T09:40:04.860316","created_date":"2025-12-23T00:00:00"}