{"id":"https://openalex.org/W7110585307","doi":null,"title":"Utility of bempedoic acid in real life","display_name":"Utility of bempedoic acid in real life","publication_year":2025,"publication_date":"2025-06-01","ids":{"openalex":"https://openalex.org/W7110585307"},"language":"es","primary_location":{"id":"pmh:oai:repositorio.unican.es:10902/37269","doi":null,"is_oa":true,"landing_page_url":"https://hdl.handle.net/10902/37269","pdf_url":null,"source":{"id":"https://openalex.org/S4306400398","display_name":"UCrea (University of Cantabria)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I13134134","host_organization_name":"Universidad de Cantabria","host_organization_lineage":["https://openalex.org/I13134134"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/bachelorThesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://hdl.handle.net/10902/37269","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Ballesteros Pacual, Teresa","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Ballesteros Pacual, Teresa","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10394","display_name":"Lipoproteins and Cardiovascular Health","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10394","display_name":"Lipoproteins and Cardiovascular Health","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11618","display_name":"Cholesterol and Lipid Metabolism","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13430","display_name":"Lipid metabolism and disorders","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/bempedoic-acid","display_name":"bempedoic acid","score":0.9990000128746033},{"id":"https://openalex.org/keywords/ldl-cholesterol-lowering","display_name":"LDL cholesterol lowering","score":0.8870000243186951},{"id":"https://openalex.org/keywords/dyslipidemia","display_name":"dyslipidemia","score":0.9340000152587891},{"id":"https://openalex.org/keywords/hypercholesterolemia","display_name":"hypercholesterolemia","score":0.8889999985694885},{"id":"https://openalex.org/keywords/treatment-adherence","display_name":"medication adherence","score":0.6079999804496765},{"id":"https://openalex.org/keywords/gout","display_name":"gout","score":0.6069999933242798},{"id":"https://openalex.org/keywords/pcsk9-inhibitors","display_name":"PCSK9 inhibitors","score":0.8159999847412109},{"id":"https://openalex.org/keywords/chronic-kidney-disease","display_name":"chronic kidney disease","score":0.875},{"id":"https://openalex.org/keywords/secondary-prevention","display_name":"secondary prevention","score":0.7360000014305115},{"id":"https://openalex.org/keywords/lipid-lowering-therapy","display_name":"lipid-lowering therapy","score":0.7620000243186951},{"id":"https://openalex.org/keywords/real-world-effectiveness","display_name":"real-world effectiveness","score":0.75},{"id":"https://openalex.org/keywords/safety-profile","display_name":"safety profile","score":0.5270000100135803},{"id":"https://openalex.org/keywords/myalgia","display_name":"myalgia","score":0.6110000014305115},{"id":"https://openalex.org/keywords/gastrointestinal-intolerance","display_name":"gastrointestinal intolerance","score":0.8149999976158142},{"id":"https://openalex.org/keywords/cardiovascular-risk-reduction","display_name":"cardiovascular risk reduction","score":0.5920000076293945},{"id":"https://openalex.org/keywords/familial-hypercholesterolemia","display_name":"familial hypercholesterolemia","score":0.8299999833106995}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8950999975204468},{"id":"https://openalex.org/C29456083","wikidata":"https://www.wikidata.org/wiki/Q1221899","display_name":"Gynecology","level":1,"score":0.47369998693466187},{"id":"https://openalex.org/C3019550498","wikidata":"https://www.wikidata.org/wiki/Q28749","display_name":"Ldl cholesterol","level":3,"score":0.3578000068664551},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.28209999203681946},{"id":"https://openalex.org/C2994423189","wikidata":"https://www.wikidata.org/wiki/Q43656","display_name":"Total cholesterol","level":3,"score":0.25049999356269836},{"id":"https://openalex.org/C3018906752","wikidata":"https://www.wikidata.org/wiki/Q844935","display_name":"Coronary heart disease","level":2,"score":0.23800000548362732},{"id":"https://openalex.org/C3018023364","wikidata":"https://www.wikidata.org/wiki/Q425265","display_name":"Significant difference","level":2,"score":0.2289000004529953},{"id":"https://openalex.org/C2778096610","wikidata":"https://www.wikidata.org/wiki/Q1476525","display_name":"Dyslipidemia","level":3,"score":0.2224999964237213},{"id":"https://openalex.org/C2994432733","wikidata":"https://www.wikidata.org/wiki/Q844935","display_name":"Coronary disease","level":3,"score":0.21969999372959137},{"id":"https://openalex.org/C2780948078","wikidata":"https://www.wikidata.org/wiki/Q21130010","display_name":"PCSK9","level":5,"score":0.21369999647140503}],"mesh":[],"locations_count":1,"locations":[{"id":"pmh:oai:repositorio.unican.es:10902/37269","doi":null,"is_oa":true,"landing_page_url":"https://hdl.handle.net/10902/37269","pdf_url":null,"source":{"id":"https://openalex.org/S4306400398","display_name":"UCrea (University of Cantabria)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I13134134","host_organization_name":"Universidad de Cantabria","host_organization_lineage":["https://openalex.org/I13134134"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/bachelorThesis"}],"best_oa_location":{"id":"pmh:oai:repositorio.unican.es:10902/37269","doi":null,"is_oa":true,"landing_page_url":"https://hdl.handle.net/10902/37269","pdf_url":null,"source":{"id":"https://openalex.org/S4306400398","display_name":"UCrea (University of Cantabria)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I13134134","host_organization_name":"Universidad de Cantabria","host_organization_lineage":["https://openalex.org/I13134134"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/bachelorThesis"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4380876358","https://openalex.org/W7127573689","https://openalex.org/W7165969532","https://openalex.org/W4205229846","https://openalex.org/W4293584900","https://openalex.org/W4417275802","https://openalex.org/W4410405692","https://openalex.org/W4387735493","https://openalex.org/W3042368998","https://openalex.org/W4408296468"],"abstract_inverted_index":{"OBJETIVO:":[0],"La":[1,154,209,222,245],"enfermedad":[2,242],"cardiovascular":[3,280],"es":[4,39,265,306],"la":[5,24,41,58,80,270,309,315],"principal":[6],"causa":[7],"de":[8,17,28,60,69,77,106,111,115,124,166,207,211,219,224,247,252,297],"muerte":[9],"a":[10,21,101,136,189,198,250],"nivel":[11],"mundial.":[12],"Entre":[13],"los":[14,29,78,89,131,167],"diversos":[15],"factores":[16],"riesgo":[18,279],"que":[19,87,99],"contribuyen":[20],"su":[22,34],"aparici\u00f3n,":[23],"dislipemia":[25],"destaca":[26],"por":[27,230],"m\u00e1s":[30],"implicados":[31],"directamente":[32],"en":[33,49,54,57,133,170,239,275,284,314],"mecanismo":[35],"patog\u00e9nico.":[36],"El":[37,164,262],"objetivo":[38],"evaluar":[40,149],"eficacia,":[42],"seguridad":[43],"y":[44,62,84,97,113,122,128,173,193,267,308],"adherencia":[45,81],"al":[46,82],"\u00e1cido":[47,107,212,248,263],"bempedoico":[48,108,249,264],"el":[50,74,85,174,301],"control":[51,302],"del":[52,65,140,142,184,227,272],"LDL":[53,186,274],"pacientes":[55,103,168,240,276],"atendidos":[56],"Unidad":[59],"L\u00edpidos":[61],"Riesgo":[63],"Cardiovascular":[64],"Hospital":[66],"Universitario":[67],"Marqu\u00e9s":[68],"Valdecilla.":[70],"Se":[71,117,144,179,235],"evalu\u00f3":[72],"tambi\u00e9n":[73],"perfil":[75,134],"cl\u00ednico-demogr\u00e1fico":[76],"pacientes,":[79],"tratamiento":[83],"porcentaje":[86],"alcanz\u00f3":[88],"objetivos":[90,259],"terap\u00e9uticos.":[91],"METODOLOG\u00cdA:":[92],"Estudio":[93],"unic\u00e9ntrico,":[94],"observacional,":[95],"descriptivo":[96],"retrospectivo":[98],"incluy\u00f3":[100],"50":[102],"con":[104,160,176,241,277,292],"indicaci\u00f3n":[105],"entre":[109],"enero":[110],"2023":[112],"junio":[114],"2024.":[116],"recopilaron":[118],"datos":[119],"cl\u00ednicos,":[120],"anal\u00edticos":[121],"demogr\u00e1ficos":[123],"historias":[125],"cl\u00ednicas":[126],"informatizadas,":[127],"se":[129],"analizaron":[130],"cambios":[132],"lip\u00eddico":[135],"las":[137],"cuatro":[138,203],"semanas":[139,206],"inicio":[141],"tratamiento.":[143,208],"aplicaron":[145],"pruebas":[146],"estad\u00edsticas":[147],"para":[148,257,269],"diferencias":[150],"significativas":[151],"(p<0,05).":[152],"RESULTADOS:":[153],"edad":[155],"media":[156],"fue":[157,214,226],"63,7":[158],"a\u00f1os,":[159],"un":[161,285],"58%":[162],"mujeres.":[163],"66%":[165],"estaban":[169],"prevenci\u00f3n":[171],"secundaria":[172],"22%":[175],"hipercolesterolemia":[177,282],"familiar.":[178],"observ\u00f3":[180],"una":[181],"reducci\u00f3n":[182,271],"significativa":[183],"colesterol":[185,194,273],"(de":[187,196],"113,4":[188],"82,9":[190],"mg/dL;":[191,200],"p<0,0001)":[192,201],"total":[195],"193,6":[197],"160,8":[199],"tras":[202],"\u2013":[204],"ocho":[205],"elevaci\u00f3n":[210],"\u00farico":[213],"significativa,":[215],"pero":[216],"sin":[217],"episodios":[218],"gota":[220],"reportados.":[221],"tasa":[223],"interrupci\u00f3n":[225],"24%,":[228],"principalmente":[229],"mialgias":[231],"e":[232],"intolerancia":[233],"digestiva.":[234],"detect\u00f3":[236],"menor":[237],"respuesta":[238],"renal":[243,311],"cr\u00f3nica.":[244],"adici\u00f3n":[246],"inhibidores":[251,296],"PCSK9":[253],"mostr\u00f3":[254],"alta":[255],"eficacia":[256],"alcanzar":[258],"lip\u00eddicos.":[260],"CONCLUSIONES:":[261],"eficaz":[266],"seguro":[268],"alto":[278],"y/o":[281],"familiar":[283],"entorno":[286],"cl\u00ednico":[287],"real.":[288],"Su":[289,304],"uso":[290],"complementario":[291],"otros":[293],"hipolipemiantes,":[294],"especialmente":[295],"PCSK9,":[298],"mejora":[299],"significativamente":[300],"lip\u00eddico.":[303],"tolerancia":[305],"adecuada":[307],"funci\u00f3n":[310],"puede":[312],"influir":[313],"respuesta.":[316]},"counts_by_year":[],"updated_date":"2026-09-26T08:19:03.415552","created_date":"2025-12-08T00:00:00"}