{"id":"https://openalex.org/W7104501945","doi":null,"title":"R\u00e9ponse Biom\u00e9canique de la Peau Humaine : Une Approche Multi-Compartiment des Milieux Poreux.","display_name":"R\u00e9ponse Biom\u00e9canique de la Peau Humaine : Une Approche Multi-Compartiment des Milieux Poreux.","publication_year":2025,"publication_date":"2025-06-24","ids":{"openalex":"https://openalex.org/W7104501945"},"language":"en","primary_location":{"id":"pmh:2025ENAME034","doi":null,"is_oa":true,"landing_page_url":"http://www.theses.fr/2025ENAME034/document","pdf_url":null,"source":{"id":"https://openalex.org/S4406923047","display_name":"theses.fr (ABES)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Electronic Thesis or Dissertation"},"volume":null,"type":"dissertation","indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://www.theses.fr/2025ENAME034/document","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5048713937","display_name":"Thomas Lavigne","orcid":"https://orcid.org/0000-0003-2690-3542","observed_orcids":["https://orcid.org/0000-0003-2690-3542"]},"institutions":[{"id":"https://openalex.org/I4210153840","display_name":"Institut de Biom\u00e9canique Humaine Georges Charpak","ror":"https://ror.org/053gdvc84","country_code":"FR","type":"facility","lineage":["https://openalex.org/I190752583","https://openalex.org/I190861549","https://openalex.org/I4210091279","https://openalex.org/I4210134562","https://openalex.org/I4210153840"]}],"countries":["FR"],"is_corresponding":true,"raw_author_name":"Lavigne, Thomas","raw_affiliation_strings":["Institut de Biom\u00e9canique Humaine Georges Charpak"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut de Biom\u00e9canique Humaine Georges Charpak","institution_ids":["https://openalex.org/I4210153840"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5048713937"],"corresponding_institution_ids":["https://openalex.org/I4210153840"],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11366","display_name":"Elasticity and Material Modeling","score":0.5644999742507935,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11366","display_name":"Elasticity and Material Modeling","score":0.5644999742507935,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11670","display_name":"Pressure Ulcer Prevention and Management","score":0.18379999697208405,"subfield":{"id":"https://openalex.org/subfields/3609","display_name":"Occupational Therapy"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10379","display_name":"Cellular Mechanics and Interactions","score":0.09480000287294388,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/skin-mechanics","display_name":"skin biomechanics","score":0.875},{"id":"https://openalex.org/keywords/tissue-damage","display_name":"tissue damage","score":0.8230000138282776},{"id":"https://openalex.org/keywords/pressure-ulcers","display_name":"pressure ulcers","score":0.7789999842643738},{"id":"https://openalex.org/keywords/skin-ischemia","display_name":"skin ischemia","score":0.3400000035762787},{"id":"https://openalex.org/keywords/mechanical-loading","display_name":"mechanical loading","score":0.4359999895095825},{"id":"https://openalex.org/keywords/tissue-deformation","display_name":"tissue deformation","score":0.43799999356269836},{"id":"https://openalex.org/keywords/microcirculation","display_name":"microcirculation","score":0.7900000214576721},{"id":"https://openalex.org/keywords/porous-media","display_name":"porous media","score":0.6119999885559082},{"id":"https://openalex.org/keywords/cell-death","display_name":"cell death","score":0.4180000126361847},{"id":"https://openalex.org/keywords/wound-healing","display_name":"wound healing","score":0.492000013589859},{"id":"https://openalex.org/keywords/immobile-patients","display_name":"immobile patients","score":0.4970000088214874},{"id":"https://openalex.org/keywords/pressure-ulcer-prevention","display_name":"pressure ulcer prevention","score":0.3230000138282776},{"id":"https://openalex.org/keywords/skin-viscoelasticity","display_name":"skin viscoelasticity","score":0.5130000114440918}],"concepts":[{"id":"https://openalex.org/C15708023","wikidata":"https://www.wikidata.org/wiki/Q80083","display_name":"Humanities","level":1,"score":0.49639999866485596},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.4765999913215637},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.2538999915122986},{"id":"https://openalex.org/C29456083","wikidata":"https://www.wikidata.org/wiki/Q1221899","display_name":"Gynecology","level":1,"score":0.22789999842643738},{"id":"https://openalex.org/C2779343474","wikidata":"https://www.wikidata.org/wiki/Q3109175","display_name":"Context (archaeology)","level":2,"score":0.19349999725818634},{"id":"https://openalex.org/C2910560433","wikidata":"https://www.wikidata.org/wiki/Q3587621","display_name":"Electrocution","level":2,"score":0.16179999709129333},{"id":"https://openalex.org/C52909226","wikidata":"https://www.wikidata.org/wiki/Q5462835","display_name":"Fluorescent labelling","level":3,"score":0.15240000188350677},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.14560000598430634},{"id":"https://openalex.org/C3017944768","wikidata":"https://www.wikidata.org/wiki/Q1450463","display_name":"Poison control","level":2,"score":0.13539999723434448},{"id":"https://openalex.org/C142362112","wikidata":"https://www.wikidata.org/wiki/Q735","display_name":"Art","level":0,"score":0.12809999287128448}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:2025ENAME034","doi":null,"is_oa":true,"landing_page_url":"http://www.theses.fr/2025ENAME034/document","pdf_url":null,"source":{"id":"https://openalex.org/S4406923047","display_name":"theses.fr (ABES)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Electronic Thesis or Dissertation"},{"id":"pmh:oai:HAL:tel-05351779v1","doi":null,"is_oa":false,"landing_page_url":"https://pastel.hal.science/tel-05351779","pdf_url":null,"source":{"id":"https://openalex.org/S4306402512","display_name":"HAL (Le Centre pour la Communication Scientifique Directe)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1294671590","host_organization_name":"Centre National de la Recherche Scientifique","host_organization_lineage":["https://openalex.org/I1294671590"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Biomechanics [physics.med-ph]. \u00c9cole Nationale Sup\u00e9rieure des Arts et M\u00e9tiers; Universit\u00e9 du Luxembourg. Facult\u00e9 des sciences, de la technologie et de la communication, 2025. English. ⟨NNT : 2025ENAME034⟩","raw_type":"info:eu-repo/semantics/doctoralThesis"}],"best_oa_location":{"id":"pmh:2025ENAME034","doi":null,"is_oa":true,"landing_page_url":"http://www.theses.fr/2025ENAME034/document","pdf_url":null,"source":{"id":"https://openalex.org/S4406923047","display_name":"theses.fr (ABES)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Electronic Thesis or Dissertation"},"sustainable_development_goals":[{"score":0.9537000060081482,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":[],"abstract_inverted_index":{"Les":[0,161],"tissus":[1],"vivants,":[2],"tels":[3,466],"que":[4,207,368,467],"la":[5,42,46,176,181,189,260,264,271,288,297,354,369,394,400,425,432,443,460,468,506],"peau,":[6],"sont":[7,80],"particuli\u00e8rement":[8],"sensibles":[9],"aux":[10],"alt\u00e9rations":[11],"m\u00e9caniques":[12,62,210,494],"et":[13,97,111,124,141,159,180,211,219,250,262,313,320,333,344,364,459,495,512,525],"physiologiques,":[14],"pouvant":[15],"conduire":[16,99],"\u00e0":[17,100,259,263,287,296,398,407,428],"l\u2019apparition":[18],"de":[19,21,25,41,45,60,119,142,147,149,155,214,234,266,303,309,325,392,418,424,431,502,520,523,526],"l\u00e9sions,":[20,105],"rougeurs":[22],"inflammatoires":[23],"ou":[24,44,58,70,93,198],"plaies":[26],"ouvertes.":[27],"Ces":[28,78,104],"alt\u00e9rations,":[29],"regroup\u00e9es":[30],"sous":[31,446,484],"le":[32,108,171,328,376,456],"terme":[33],"d\u2019\u00ab":[34],"endommagement":[35],"tissulaire":[36],"\u00bb,":[37],"d\u00e9signent":[38],"toute":[39],"d\u00e9gradation":[40],"structure":[43],"fonction":[47],"du":[48,247,322,357,396,403,509],"tissu.":[49],"Elles":[50],"peuvent":[51,98],"survenir":[52],"dans":[53,375],"des":[54,101,134,144,174,273,300,463,492],"conditions":[55,348],"physiologiques":[56],"normales":[57],"r\u00e9sulter":[59],"contraintes":[61,244],"externes,":[63],"telles":[64],"qu\u2019une":[65],"pression":[66],"mod\u00e9r\u00e9e":[67],"mais":[68],"prolong\u00e9e,":[69,91],"au":[71,416],"contraire,":[72],"une":[73,131,256,408,412,429,474,489],"charge":[74,128],"intense":[75],"appliqu\u00e9e":[76],"brutalement.":[77],"situations":[79],"fr\u00e9quentes":[81],"chez":[82],"les":[83,86,112,208,221,224,240,316,480],"patients":[84],"hospitalis\u00e9s,":[85],"personnes":[87],"en":[88,94,127,166,196,199,338,486,504],"situation":[89],"d\u2019immobilit\u00e9":[90],"alit\u00e9es":[92],"fauteuil":[95],"roulant,":[96],"complications":[102],"graves.":[103],"accentu\u00e9es":[106],"par":[107,434],"vieillissement":[109],"d\u00e9mographique":[110],"habitudes":[113],"s\u00e9dentaires,":[114],"constituent":[115],"un":[116,168,193,499],"enjeu":[117],"majeur":[118],"sant\u00e9":[120],"publique.":[121],"Leur":[122],"pr\u00e9vention":[123,524],"leur":[125,139,284,294],"prise":[126],"reposent":[129],"sur":[130,387,422,488],"meilleure":[132],"compr\u00e9hension":[133],"m\u00e9canismes":[135,481],"sous-jacents,":[136],"afin":[137],"d\u2019anticiper":[138],"survenue":[140],"d\u00e9velopper":[143],"strat\u00e9gies":[145,522],"personnalis\u00e9es":[146],"soin.L\u2019apparition":[148],"l\u00e9sions":[150],"tissulaires":[151],"r\u00e9sulte":[152],"d\u2019un":[153],"enchev\u00eatrement":[154],"facteurs":[156],"m\u00e9caniques,":[157,245],"biologiques":[158,321,465],"individuels.":[160],"\u00e9tudes":[162],"animales":[163],"ont":[164,205,390],"mis":[165],"\u00e9vidence":[167],"lien":[169],"entre":[170,243,330,479],"chargement":[172,331,447],"m\u00e9canique":[173,191,332],"tissus,":[175],"privation":[177],"d\u2019oxyg\u00e8ne":[178],"(isch\u00e9mie)":[179],"mort":[182],"cellulaire,":[183],"cette":[184,419,516],"derni\u00e8re":[185],"survenant":[186],"notamment":[187],"lorsque":[188],"d\u00e9formation":[190,246],"d\u00e9passe":[192],"seuil":[194],"critique,":[195],"compression":[197],"cisaillement.":[200],"De":[201],"plus,":[202],"plusieurs":[203],"travaux":[204],"montr\u00e9":[206],"effets":[209],"isch\u00e9miques":[212],"agissent":[213],"mani\u00e8re":[215,235],"synergique":[216],"pour":[217,276,441,454,476],"initier":[218],"propager":[220],"l\u00e9sions.":[222],"Toutefois,":[223],"mod\u00e8les":[225,279],"math\u00e9matiques":[226],"actuels":[227],"traitent":[228],"encore":[229],"trop":[230],"souvent":[231],"ces":[232,267,278],"dimensions":[233],"s\u00e9par\u00e9e,":[236],"sans":[237],"int\u00e9grer":[238,455],"explicitement":[239],"interactions":[241],"dynamiques":[242],"tissu,":[248,323],"microcirculation":[249,370],"r\u00e9ponse":[251,334,401,444],"biologique.":[252],"Ce":[253],"cloisonnement":[254],"constitue":[255],"limite":[257],"importante":[258],"pr\u00e9dictivit\u00e9":[261],"transf\u00e9rabilit\u00e9":[265],"mod\u00e8les.":[268],"Par":[269],"ailleurs,":[270],"majorit\u00e9":[272],"donn\u00e9es":[274,381],"utilis\u00e9es":[275],"calibrer":[277],"provient":[280],"d\u2019animaux,":[281],"rendant":[282],"difficile":[283],"application":[285],"directe":[286],"peau":[289,388,426],"humaine":[290,389],"et,":[291],"a":[292,372,438,451],"fortiori,":[293],"adaptation":[295],"variabilit\u00e9":[298,514],"interindividuelle":[299],"patients.L\u2019hypoth\u00e8se":[301],"centrale":[302],"ce":[304],"travail":[305,471],"est":[306],"qu\u2019un":[307],"cadre":[308],"mod\u00e9lisation":[310,342,490],"porom\u00e9canique,":[311],"multi-phasique":[312],"multi-\u00e9chelle,":[314],"int\u00e9grant":[315,353],"composantes":[317],"structurelles,":[318],"fluidiques":[319],"permettrait":[324],"mieux":[326],"caract\u00e9riser":[327,442],"couplage":[329],"microvasculaire.La":[335],"strat\u00e9gie":[336],"mise":[337],"\u0153uvre":[339],"combine":[340],"\u00e9troitement":[341],"math\u00e9matique":[343],"validation":[345],"exp\u00e9rimentale":[346,414],"(en":[347],"physiologiques).":[349],"Une":[350],"formulation":[351],"porom\u00e9canique":[352],"phase":[355],"solide":[356],"tissu":[358,404,510],"cutan\u00e9,":[359],"l\u2019interstitium":[360],"(incluant":[361],"fluide":[362],"interstitiel":[363],"cellules":[365],"mobiles),":[366],"ainsi":[367,473],"vasculaire,":[371],"\u00e9t\u00e9":[373,439,452],"impl\u00e9ment\u00e9e":[374],"logiciel":[377],"open-source":[378],"FEniCSx.":[379],"Des":[380],"exp\u00e9rimentales":[382],"d\u2019essais":[383],"d\u2019extension":[384],"extit{in":[385],"vivo}":[386],"permis":[391],"valider":[393],"capacit\u00e9":[395],"mod\u00e8le":[397,450],"reproduire":[399],"temporelle":[402],"cutan\u00e9":[405,483],"soumis":[406],"sollicitation":[409],"m\u00e9canique.":[410],"Puis":[411],"\u00e9tude":[413],"r\u00e9alis\u00e9e":[415],"cours":[417],"th\u00e8se,":[420],"reposant":[421],"l\u2019indentation":[423],"coupl\u00e9e":[427,491],"mesure":[430],"perfusion":[433],"sonde":[435],"laser":[436],"Doppler,":[437],"conduite":[440],"microcirculatoire":[445],"externe.":[448],"Le":[449],"enrichi":[453],"r\u00e9seau":[457],"vasculaire":[458],"possibilit\u00e9":[461],"d\u2019incorporer":[462],"processus":[464,493],"diffusion":[469],"d'oxyg\u00e8ne.Ce":[470],"propose":[472],"approche":[475],"\u00e9tudier":[477],"l\u2019interaction":[478],"d\u2019endommagement":[482],"contrainte,":[485],"s\u2019appuyant":[487],"biologiques.":[496],"En":[497],"offrant":[498],"outil":[500],"capable":[501],"prendre":[503],"compte":[505],"complexit\u00e9":[507],"multi-\u00e9chelle":[508],"humain":[511],"sa":[513],"interindividuelle,":[515],"recherche":[517],"pourrait":[518],"inspirer":[519],"meilleures":[521],"traitement":[527],"personnalis\u00e9s.":[528]},"counts_by_year":[],"updated_date":"2026-10-13T10:08:12.033832","created_date":"2025-11-09T00:00:00"}