{"id":"https://openalex.org/W7098091690","doi":null,"title":"Competing Interests: The authors have declared that no competing interests exist.","display_name":"Competing Interests: The authors have declared that no competing interests exist.","publication_year":2007,"publication_date":"2007-01-01","ids":{"openalex":"https://openalex.org/W7098091690"},"language":"en","primary_location":{"id":"pmh:oai:CiteSeerX.psu:10.1.1.275.3385","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.275.3385","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"ftp://ftp.ncbi.nlm.nih.gov/pub/pmc/ac/64/PLoS_ONE_2008_Apr_9_3(4)_e1959.tar.gz","raw_type":"text"},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5011120608","display_name":"David Dupret","orcid":"https://orcid.org/0000-0002-0040-1766","observed_orcids":["https://orcid.org/0000-0002-0040-1766"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"David Dupret","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006763630","display_name":"Jean\u2010Michel Revest","orcid":"https://orcid.org/0000-0001-6459-0888","observed_orcids":["https://orcid.org/0000-0001-6459-0888"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jean-michel Revest","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066200333","display_name":"Muriel Koehl","orcid":"https://orcid.org/0000-0002-7601-1422","observed_orcids":["https://orcid.org/0000-0002-7601-1422"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Muriel Koehl","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072906655","display_name":"Fran\u00e7ois Ichas","orcid":"https://orcid.org/0000-0001-8184-5248","observed_orcids":["https://orcid.org/0000-0001-8184-5248"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Fran\u00e7ois Ichas","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045657404","display_name":"Francesca De Giorgi","orcid":"https://orcid.org/0000-0003-4850-3582","observed_orcids":["https://orcid.org/0000-0003-4850-3582"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Francesca De Giorgi","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074144950","display_name":"Djoher Nora Abrous","orcid":"https://orcid.org/0000-0002-8589-305X","observed_orcids":["https://orcid.org/0000-0002-8589-305X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Djoher Nora Abrous","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":null,"display_name":"Pier Vincenzo Piazza","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Pier Vincenzo Piazza","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.43032787,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":true,"primary_topic":{"id":"https://openalex.org/T10608","display_name":"Neurogenesis and neuroplasticity mechanisms","score":0.9872999787330627,"subfield":{"id":"https://openalex.org/subfields/2806","display_name":"Developmental Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10608","display_name":"Neurogenesis and neuroplasticity mechanisms","score":0.9872999787330627,"subfield":{"id":"https://openalex.org/subfields/2806","display_name":"Developmental Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10448","display_name":"Memory and Neural Mechanisms","score":0.012600000016391277,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/adult-neurogenesis","display_name":"adult neurogenesis","score":0.9330000281333923},{"id":"https://openalex.org/keywords/dentate-gyrus","display_name":"dentate gyrus","score":0.9869999885559082},{"id":"https://openalex.org/keywords/hippocampus","display_name":"hippocampus","score":0.9599999785423279},{"id":"https://openalex.org/keywords/spatial-memory","display_name":"spatial memory","score":0.9660000205039978},{"id":"https://openalex.org/keywords/hippocampal-neurons","display_name":"hippocampal neurons","score":0.7409999966621399},{"id":"https://openalex.org/keywords/spatial-learning","display_name":"spatial learning","score":0.4519999921321869}],"concepts":[{"id":"https://openalex.org/C2776464000","wikidata":"https://www.wikidata.org/wiki/Q545787","display_name":"Dentate gyrus","level":3,"score":0.8967999815940857},{"id":"https://openalex.org/C4746552","wikidata":"https://www.wikidata.org/wiki/Q1456827","display_name":"Neurogenesis","level":2,"score":0.810699999332428},{"id":"https://openalex.org/C148762608","wikidata":"https://www.wikidata.org/wiki/Q3748185","display_name":"Hippocampal formation","level":2,"score":0.6209999918937683},{"id":"https://openalex.org/C2781161787","wikidata":"https://www.wikidata.org/wiki/Q48360","display_name":"Hippocampus","level":2,"score":0.5893999934196472},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.5697000026702881},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.4498000144958496},{"id":"https://openalex.org/C89611455","wikidata":"https://www.wikidata.org/wiki/Q6804646","display_name":"Mechanism (biology)","level":2,"score":0.37470000982284546},{"id":"https://openalex.org/C188147891","wikidata":"https://www.wikidata.org/wiki/Q147638","display_name":"Cognitive science","level":1,"score":0.36809998750686646},{"id":"https://openalex.org/C180747234","wikidata":"https://www.wikidata.org/wiki/Q23373","display_name":"Cognitive psychology","level":1,"score":0.35899999737739563},{"id":"https://openalex.org/C170494330","wikidata":"https://www.wikidata.org/wiki/Q1778434","display_name":"Cognitive map","level":3,"score":0.328900009393692},{"id":"https://openalex.org/C3020766347","wikidata":"https://www.wikidata.org/wiki/Q1073","display_name":"Mammalian brain","level":2,"score":0.31150001287460327},{"id":"https://openalex.org/C169900460","wikidata":"https://www.wikidata.org/wiki/Q2200417","display_name":"Cognition","level":2,"score":0.3089999854564667},{"id":"https://openalex.org/C2986522900","wikidata":"https://www.wikidata.org/wiki/Q2178623","display_name":"Spatial relationship","level":2,"score":0.30720001459121704},{"id":"https://openalex.org/C11671645","wikidata":"https://www.wikidata.org/wiki/Q5054567","display_name":"Causal model","level":2,"score":0.27459999918937683},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.273499995470047},{"id":"https://openalex.org/C2985665543","wikidata":"https://www.wikidata.org/wiki/Q3560550","display_name":"Spatial learning","level":3,"score":0.2694999873638153},{"id":"https://openalex.org/C141035611","wikidata":"https://www.wikidata.org/wiki/Q5532934","display_name":"Genetically modified mouse","level":4,"score":0.25839999318122864},{"id":"https://openalex.org/C159620131","wikidata":"https://www.wikidata.org/wiki/Q1938983","display_name":"Spatial analysis","level":2,"score":0.2558000087738037},{"id":"https://openalex.org/C2775858120","wikidata":"https://www.wikidata.org/wiki/Q3333604","display_name":"Memoria","level":3,"score":0.2506999969482422}],"mesh":[],"locations_count":1,"locations":[{"id":"pmh:oai:CiteSeerX.psu:10.1.1.275.3385","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.275.3385","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"ftp://ftp.ncbi.nlm.nih.gov/pub/pmc/ac/64/PLoS_ONE_2008_Apr_9_3(4)_e1959.tar.gz","raw_type":"text"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2010053974","https://openalex.org/W62812527","https://openalex.org/W2317682367","https://openalex.org/W1948207118","https://openalex.org/W1979782640","https://openalex.org/W2618108759","https://openalex.org/W2095812114","https://openalex.org/W247553582","https://openalex.org/W7043032572","https://openalex.org/W2002159284"],"abstract_inverted_index":{"The":[0],"dentate":[1],"gyrus":[2],"of":[3,8,12,60,69,87,103],"the":[4,9,13],"hippocampus":[5],"is":[6],"one":[7],"few":[10],"regions":[11],"mammalian":[14],"brain":[15],"where":[16],"new":[17],"neurons":[18,97],"are":[19,48,98],"generated":[20],"throughout":[21],"adulthood.":[22],"This":[23,64],"adult":[24],"neurogenesis":[25,44],"has":[26],"been":[27],"proposed":[28],"as":[29],"a":[30,40,75],"novel":[31],"mechanism":[32],"that":[33,95],"mediates":[34],"spatial":[35,46,70,88],"memory.":[36],"However,":[37],"data":[38],"showing":[39],"causal":[41],"relationship":[42],"between":[43],"and":[45],"memory":[47,80],"controversial.":[49],"Here,":[50],"we":[51],"developed":[52],"an":[53,67],"inducible":[54],"transgenic":[55],"strategy":[56],"allowing":[57],"specific":[58],"ablation":[59],"adult-born":[61,96],"hippocampal":[62],"neurons.":[63],"resulted":[65],"in":[66],"impairment":[68],"relational":[71],"memory,":[72],"which":[73],"supports":[74],"capacity":[76],"for":[77,100],"flexible,":[78],"inferential":[79],"expression.":[81],"In":[82],"contrast,":[83],"less":[84],"complex":[85,101],"forms":[86,102],"knowledge":[89],"were":[90],"unaltered.":[91],"These":[92],"findings":[93],"demonstrate":[94],"necessary":[99],"hippocampus-mediated":[104],"learning.":[105]},"counts_by_year":[],"updated_date":"2026-10-13T10:08:12.033832","created_date":"2025-10-27T00:00:00"}