{"id":"https://openalex.org/W7096374197","doi":null,"title":"Printed in U.S.A. Copyright \u00a9 1999 by The Endocrine Society The Impact of the Nonpeptide Corticotropin-Releasing Hormone Antagonist Antalarmin on Behavioral and Endocrine Responses to Stress*","display_name":"Printed in U.S.A. Copyright \u00a9 1999 by The Endocrine Society The Impact of the Nonpeptide Corticotropin-Releasing Hormone Antagonist Antalarmin on Behavioral and Endocrine Responses to Stress*","publication_year":2013,"publication_date":"2013-08-26","ids":{"openalex":"https://openalex.org/W7096374197"},"language":"en","primary_location":{"id":"pmh:oai:CiteSeerX.psu:10.1.1.335.8639","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.335.8639","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://psych.colorado.edu/~spencer/Spencer Lab Reprints/Deak1999Endo.pdf","raw_type":"text"},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5078833825","display_name":"Terrence Deak","orcid":"https://orcid.org/0000-0002-1514-4600","observed_orcids":["https://orcid.org/0000-0002-1514-4600"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Terrence Deak","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"Kien T. Nguyen","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Kien T. Nguyen","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066148080","display_name":"Andrea L. Ehrlich","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Andrea L. Ehrlich","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"Linda R. Watkins","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Linda R. Watkins","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"Robert L. Spencer","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Robert L. Spencer","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022821273","display_name":"STEVEN F MAIER","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Steven F. Maier","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021913455","display_name":"J\u00falio Licinio","orcid":"https://orcid.org/0000-0001-6905-5884","observed_orcids":["https://orcid.org/0000-0001-6905-5884"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Julio Licinio","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"Ma-li Wong","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ma-li Wong","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":null,"display_name":"George P. Chrousos","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"George P. Chrousos","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":true,"primary_topic":{"id":"https://openalex.org/T10529","display_name":"Stress Responses and Cortisol","score":0.8476999998092651,"subfield":{"id":"https://openalex.org/subfields/2802","display_name":"Behavioral Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10529","display_name":"Stress Responses and Cortisol","score":0.8476999998092651,"subfield":{"id":"https://openalex.org/subfields/2802","display_name":"Behavioral Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10814","display_name":"Neuropeptides and Animal Physiology","score":0.13529999554157257,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10448","display_name":"Memory and Neural Mechanisms","score":0.005400000140070915,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/antalarmin","display_name":"antalarmin","score":0.9990000128746033},{"id":"https://openalex.org/keywords/corticotropin-releasing-factor","display_name":"corticotropin-releasing factor","score":0.9190000295639038},{"id":"https://openalex.org/keywords/fear-conditioning","display_name":"fear conditioning","score":0.9049999713897705},{"id":"https://openalex.org/keywords/freezing-behavior","display_name":"freezing behavior","score":0.7710000276565552},{"id":"https://openalex.org/keywords/stress","display_name":"stress","score":0.38999998569488525},{"id":"https://openalex.org/keywords/endocrine-stress-response","display_name":"endocrine stress response","score":0.7039999961853027}],"concepts":[{"id":"https://openalex.org/C46699223","wikidata":"https://www.wikidata.org/wiki/Q11078","display_name":"Endocrine system","level":3,"score":0.7355999946594238},{"id":"https://openalex.org/C2776885963","wikidata":"https://www.wikidata.org/wiki/Q245204","display_name":"Antagonist","level":3,"score":0.6680999994277954},{"id":"https://openalex.org/C2779343474","wikidata":"https://www.wikidata.org/wiki/Q3109175","display_name":"Context (archaeology)","level":2,"score":0.6445000171661377},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.642300009727478},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.5577999949455261},{"id":"https://openalex.org/C2778468042","wikidata":"https://www.wikidata.org/wiki/Q273976","display_name":"Blockade","level":3,"score":0.5522000193595886},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5271999835968018},{"id":"https://openalex.org/C2777383412","wikidata":"https://www.wikidata.org/wiki/Q4770891","display_name":"Antagonism","level":3,"score":0.4794999957084656},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.42239999771118164},{"id":"https://openalex.org/C2778458438","wikidata":"https://www.wikidata.org/wiki/Q386664","display_name":"Corticotropin-releasing hormone","level":3,"score":0.41119998693466187},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.35740000009536743},{"id":"https://openalex.org/C182203180","wikidata":"https://www.wikidata.org/wiki/Q324663","display_name":"Endocrine gland","level":3,"score":0.3531000018119812},{"id":"https://openalex.org/C2107291","wikidata":"https://www.wikidata.org/wiki/Q14886885","display_name":"Mediator","level":2,"score":0.3427000045776367},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.3192000091075897},{"id":"https://openalex.org/C2778122271","wikidata":"https://www.wikidata.org/wiki/Q410943","display_name":"Receptor antagonist","level":4,"score":0.29269999265670776},{"id":"https://openalex.org/C2777886879","wikidata":"https://www.wikidata.org/wiki/Q16875676","display_name":"Hormone antagonist","level":4,"score":0.2766999900341034},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.25119999051094055}],"mesh":[],"locations_count":1,"locations":[{"id":"pmh:oai:CiteSeerX.psu:10.1.1.335.8639","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.335.8639","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://psych.colorado.edu/~spencer/Spencer Lab Reprints/Deak1999Endo.pdf","raw_type":"text"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.8048999905586243,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4234048661","https://openalex.org/W2149878393","https://openalex.org/W1975218744","https://openalex.org/W2065139995","https://openalex.org/W1963722749","https://openalex.org/W4237467817","https://openalex.org/W1979216601","https://openalex.org/W2896847387","https://openalex.org/W2022390810","https://openalex.org/W2048465808"],"abstract_inverted_index":{"The":[0],"nonpeptide":[1],"CRH":[2,38,41,78],"antagonist":[3],"antalarmin":[4,50],"has":[5,30],"been":[6,32],"shown":[7],"to":[8,15,48,60],"block":[9],"both":[10],"behavioral":[11,23],"and":[12,24],"endocrine":[13,25],"responses":[14],"CRH.":[16],"However,":[17],"it\u2019s":[18],"potential":[19],"activity":[20],"in":[21,51,88],"blunting":[22],"sequelae":[26],"of":[27,36,66,84],"stressor":[28],"exposure":[29],"not":[31],"assessed.":[33],"Because":[34],"antagonism":[35],"central":[37],"by":[39],"\ufffd-helical":[40],"attenuates":[42],"conditioned":[43,85],"fear":[44,86],"responses,":[45],"we":[46,75],"sought":[47],"test":[49],"this":[52,62],"regard.":[53],"In":[54],"addition,":[55],"it":[56],"remains":[57],"unclear":[58],"as":[59],"whether":[61,77],"is":[63],"a":[64,89],"result":[65],"receptor":[67],"blockade":[68],"during":[69,72],"conditioning":[70],"or":[71,82],"testing.":[73],"Thus,":[74],"explored":[76],"mediates":[79],"the":[80],"induction":[81],"expression":[83],"(freezing":[87],"context":[90],"previously":[91],"associated":[92],"with":[93],"2":[94],"footshocks;":[95],"1.0":[96],"mA,":[97],"5":[98],"sec":[99],"each).":[100]},"counts_by_year":[],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2025-10-27T00:00:00"}