{"id":"https://openalex.org/W7094584185","doi":null,"title":"Origine de l'homochiralit\u00e9 de la terre: investigations th\u00e9oriques et exp\u00e9rimentales","display_name":"Origine de l'homochiralit\u00e9 de la terre: investigations th\u00e9oriques et exp\u00e9rimentales","publication_year":2009,"publication_date":"2009-02-17","ids":{"openalex":"https://openalex.org/W7094584185"},"language":"fr","primary_location":{"id":"pmh:oai:dipot.ulb.ac.be:2013/210362","doi":null,"is_oa":true,"landing_page_url":"https://dipot.ulb.ac.be/dspace/bitstream/2013/210362/1/223551f6-450e-476c-a948-feb0f4c1e230.txt","pdf_url":null,"source":{"id":"https://openalex.org/S4306401063","display_name":"D\u00e9p\u00f4t institutionnel de l'Universit\u00e9 libre de Bruxelles (Universit\u00e9 Libre de Bruxelles)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I132053463","host_organization_name":"Universit\u00e9 Libre de Bruxelles","host_organization_lineage":["https://openalex.org/I132053463"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/doctoralThesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://dipot.ulb.ac.be/dspace/bitstream/2013/210362/1/223551f6-450e-476c-a948-feb0f4c1e230.txt","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Vandenbussche, Sophie","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Vandenbussche, Sophie","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":true,"primary_topic":{"id":"https://openalex.org/T11445","display_name":"Origins and Evolution of Life","score":1.0,"subfield":{"id":"https://openalex.org/subfields/3103","display_name":"Astronomy and Astrophysics"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11445","display_name":"Origins and Evolution of Life","score":1.0,"subfield":{"id":"https://openalex.org/subfields/3103","display_name":"Astronomy and Astrophysics"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12788","display_name":"Space Science and Extraterrestrial Life","score":0.0,"subfield":{"id":"https://openalex.org/subfields/3103","display_name":"Astronomy and Astrophysics"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/homochirality","display_name":"homochirality","score":0.8389999866485596},{"id":"https://openalex.org/keywords/origin-of-homochirality","display_name":"origin of homochirality","score":0.9660000205039978},{"id":"https://openalex.org/keywords/origin-of-life","display_name":"origin of life","score":0.8930000066757202},{"id":"https://openalex.org/keywords/enantiomeric-excess","display_name":"enantiomeric excess","score":0.9539999961853027},{"id":"https://openalex.org/keywords/circularly-polarized-light","display_name":"circularly polarized light","score":0.8159999847412109},{"id":"https://openalex.org/keywords/photolysis","display_name":"photolysis","score":0.6380000114440918},{"id":"https://openalex.org/keywords/electronic-circular-dichroism","display_name":"electronic circular dichroism","score":0.8270000219345093},{"id":"https://openalex.org/keywords/circular-dichroism","display_name":"circular dichroism","score":0.5210000276565552},{"id":"https://openalex.org/keywords/alpha-hydroxy-acids","display_name":"\u03b1-hydroxy acids","score":0.8240000009536743},{"id":"https://openalex.org/keywords/meteorites","display_name":"meteorites","score":0.6449999809265137},{"id":"https://openalex.org/keywords/rna-nucleotides","display_name":"RNA nucleotides","score":0.6600000262260437},{"id":"https://openalex.org/keywords/chirality-transfer","display_name":"chirality transfer","score":0.6050000190734863},{"id":"https://openalex.org/keywords/prebiotic-chemistry","display_name":"prebiotic chemistry","score":0.5410000085830688}],"concepts":[{"id":"https://openalex.org/C146888428","wikidata":"https://www.wikidata.org/wiki/Q903478","display_name":"Homochirality","level":3,"score":0.9843999743461609},{"id":"https://openalex.org/C190161988","wikidata":"https://www.wikidata.org/wiki/Q231218","display_name":"Abiogenesis","level":2,"score":0.7003999948501587},{"id":"https://openalex.org/C87355193","wikidata":"https://www.wikidata.org/wiki/Q411","display_name":"Astrobiology","level":1,"score":0.6593999862670898},{"id":"https://openalex.org/C124668440","wikidata":"https://www.wikidata.org/wiki/Q2305173","display_name":"Chirality (physics)","level":5,"score":0.6407999992370605},{"id":"https://openalex.org/C155242204","wikidata":"https://www.wikidata.org/wiki/Q407525","display_name":"RNA world hypothesis","level":5,"score":0.5809000134468079},{"id":"https://openalex.org/C486523","wikidata":"https://www.wikidata.org/wiki/Q494483","display_name":"Enantiomer","level":2,"score":0.5249999761581421},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.47040000557899475},{"id":"https://openalex.org/C24107716","wikidata":"https://www.wikidata.org/wiki/Q123619","display_name":"Nucleic acid","level":2,"score":0.43860000371932983},{"id":"https://openalex.org/C130635790","wikidata":"https://www.wikidata.org/wiki/Q60186","display_name":"Meteorite","level":2,"score":0.41850000619888306},{"id":"https://openalex.org/C2776744078","wikidata":"https://www.wikidata.org/wiki/Q5326645","display_name":"Early Earth","level":2,"score":0.40869998931884766},{"id":"https://openalex.org/C26148502","wikidata":"https://www.wikidata.org/wiki/Q2488752","display_name":"Earth (classical element)","level":2,"score":0.36649999022483826},{"id":"https://openalex.org/C67705224","wikidata":"https://www.wikidata.org/wiki/Q11053","display_name":"RNA","level":3,"score":0.36070001125335693},{"id":"https://openalex.org/C2779461342","wikidata":"https://www.wikidata.org/wiki/Q59817493","display_name":"Ribose","level":3,"score":0.33059999346733093},{"id":"https://openalex.org/C78458016","wikidata":"https://www.wikidata.org/wiki/Q840400","display_name":"Evolutionary biology","level":1,"score":0.31040000915527344},{"id":"https://openalex.org/C2776184637","wikidata":"https://www.wikidata.org/wiki/Q6506039","display_name":"Living systems","level":2,"score":0.3084000051021576},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2948000133037567},{"id":"https://openalex.org/C204389451","wikidata":"https://www.wikidata.org/wiki/Q178593","display_name":"Macromolecule","level":2,"score":0.2870999872684479},{"id":"https://openalex.org/C3141732","wikidata":"https://www.wikidata.org/wiki/Q568761","display_name":"Enantiomeric excess","level":4,"score":0.27959999442100525},{"id":"https://openalex.org/C168167062","wikidata":"https://www.wikidata.org/wiki/Q1117970","display_name":"Component (thermodynamics)","level":2,"score":0.27570000290870667},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.2605000138282776},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.2529999911785126}],"mesh":[],"locations_count":1,"locations":[{"id":"pmh:oai:dipot.ulb.ac.be:2013/210362","doi":null,"is_oa":true,"landing_page_url":"https://dipot.ulb.ac.be/dspace/bitstream/2013/210362/1/223551f6-450e-476c-a948-feb0f4c1e230.txt","pdf_url":null,"source":{"id":"https://openalex.org/S4306401063","display_name":"D\u00e9p\u00f4t institutionnel de l'Universit\u00e9 libre de Bruxelles (Universit\u00e9 Libre de Bruxelles)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I132053463","host_organization_name":"Universit\u00e9 Libre de Bruxelles","host_organization_lineage":["https://openalex.org/I132053463"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/doctoralThesis"}],"best_oa_location":{"id":"pmh:oai:dipot.ulb.ac.be:2013/210362","doi":null,"is_oa":true,"landing_page_url":"https://dipot.ulb.ac.be/dspace/bitstream/2013/210362/1/223551f6-450e-476c-a948-feb0f4c1e230.txt","pdf_url":null,"source":{"id":"https://openalex.org/S4306401063","display_name":"D\u00e9p\u00f4t institutionnel de l'Universit\u00e9 libre de Bruxelles (Universit\u00e9 Libre de Bruxelles)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I132053463","host_organization_name":"Universit\u00e9 Libre de Bruxelles","host_organization_lineage":["https://openalex.org/I132053463"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/doctoralThesis"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W1428236614","https://openalex.org/W7070446841","https://openalex.org/W2026566544","https://openalex.org/W4389582259","https://openalex.org/W7023670764","https://openalex.org/W7098904707","https://openalex.org/W2037827350","https://openalex.org/W3117181775","https://openalex.org/W4407775911","https://openalex.org/W2018847257"],"abstract_inverted_index":{"Chirality":[0],"is":[1,67,82,126,135,174,266,642,694,704,728,776,822],"the":[2,25,71,74,94,99,130,151,162,188,194,210,228,232,260,269,273,293,313,316,343,358,388,394,398,408,421,428,432,438,457,462,470,473,480,488,497,525,538,548,566,602,640,645,666,686,719,736,757,765,779,783,799,812,838,847,860],"property":[3],"of":[4,27,46,62,73,79,101,110,122,132,212,217,227,230,234,238,247,296,315,320,345,364,407,420,434,440,461,464,472,520,524,569,604,647,651,668,672,688,699,738,767,771,782,785,798,849,853],"objects,":[5],"including":[6],"molecules,":[7,108],"which":[8,153,255,469,598],"are":[9,19,34,52,332,376,599,619,627],"not":[10,620,858],"superimposable":[11],"on":[12,124,159,187,193,214,257,436,466,547,654,718,746],"their":[13,63,368],"materialized":[14],"mirror":[15],"image.":[16],"Chiral":[17],"molecules":[18],"omnipresent":[20],"in":[21,56,93,253,272,308,397,431,479,487,537,574,585,607,622,632,639,644,764,811,846,867],"living":[22,57,75],"organisms":[23,58],"and":[24,31,40,48,113,134,157,168,178,190,277,371,381,508,522,576,595,624,650,692,740,803,830],"constituents":[26],"biological":[28],"macromolecules":[29],"(proteins":[30],"nucleic":[32],"acids)":[33],"chiral.":[35],"Amino-acids":[36],"(constituting":[37],"proteins),":[38],"ribose":[39,682,693],"2-deoxy-ribose":[41],"(the":[42],"only":[43,59,163,630,695],"chiral":[44,118,447],"constituent":[45],"RNA":[47,239,673,739,749,772,854],"DNA":[49],"nucleotides":[50],"respectively)":[51],"furthermore":[53],"generally":[54],"present":[55,621,717,745],"under":[60,722],"one":[61,372,723],"enantiomeric":[64,104,264,284,322,443,458,516,724],"forms.":[65],"This":[66,425,774],"referred":[68],"to":[69,116,129,138,148,155,166,175,209,222,244,328,334,356,386,456,502,509,540,601,612,681,685,778,808],"as":[70,236,670,769,851],"homochirality":[72,81,123,213,435,465],"world.":[76],"The":[77,120,449,636,675],"origin":[78,121,131,211,229,314,433,463,784],"this":[80,111,172,543,588,753,868],"still":[83],"unexplained,":[84],"even":[85],"if":[86,301,565,581,625],"many":[87,689],"partial":[88],"scenarios":[89,97,207,219],"have":[90,139,250,286,484,510,545,708,762,844,865],"been":[91,251,287,477,485,500,528,535,709],"proposed":[92,536],"literature.":[95,481],"All":[96],"involve":[98],"creation":[100,439],"a":[102,223,346,384,441,504,511,662,696,731],"small":[103,278,442],"excess":[105,112,265,323,444],"for":[106,268,289,324,445,468,513,665],"certain":[107],"amplification":[109,459,517],"chirality":[114,787],"transfer":[115],"other":[117,690],"molecules.":[119,448],"Earth":[125,196,258,721,747],"closely":[127],"related":[128,208,777],"life,":[133,158],"currently":[136,676],"supposed":[137],"preceded":[140],"life.":[141],"As":[142,657],"no-one":[143],"will":[144],"ever":[145],"be":[146,311,503,631],"able":[147,611,807],"directly":[149],"observe":[150],"phenomena":[152],"lead":[154,684],"homochirality,":[156],"our":[160,202,297,349,648],"planet,":[161],"scientific":[164],"approach":[165],"try":[167],"help":[169],"explain":[170,387,541],"how":[171,542],"occurred":[173,546],"build":[176],"scenarios,":[177],"test":[179],"them":[180],"taking":[181],"into":[182],"account":[183],"all":[184],"available":[185],"information":[186],"physical":[189],"chemical":[191],"conditions":[192,417],"primitive":[195,549,720],"(Earth":[197],"before":[198,735],"life":[199],"appeared).":[200],"In":[201,292,348],"work,":[203,298,350],"we":[204,299,351,382,453,578,590,660,755,815],"investigated":[205,300,454,580,661,756,792],"three":[206],"Earth.":[215],"One":[216],"these":[218,325,379,416,495,700],"also":[220,572,683],"relates":[221,455],"very":[224,823],"precise":[225],"step":[226,430,460,781],"life:":[231],"selection":[233,667,766,848],"beta-d-ribofuranose":[235,669,706,850],"component":[237,671,770,852],"nucleotides.":[240,674,773],"Enantiomeric":[241],"excesses":[242,285],"(up":[243],"15":[245],"%)":[246],"alpha-methylated":[248],"alpha-amino-acids":[249,409,715,743,802,841],"detected":[252,267],"meteorites":[254],"fell":[256],"during":[259],"20th":[261],"century.":[262],"No":[263,530],"corresponding":[270,369],"alpha-hydroxy-acids":[271,370,422],"same":[274],"meteoritic":[275],"samples":[276],"(2%":[279],"at":[280,312,401,405,563],"most)":[281],"or":[282],"no":[283,418],"measured":[288],"non-methylated":[290,373],"alpha-amino-acids.":[291],"first":[294,429,579],"part":[295],"photolysis":[302,331,419],"by":[303,410,491],"circularly":[304,339],"polarized":[305,340],"light":[306,646],"(CPL)":[307],"space":[309],"could":[310,544,629,707,761,843,864],"presence":[317,737],"(or":[318],"absence)":[319],"an":[321,558,818],"compounds.":[326],"Experiments":[327],"reproduce":[329],"UV-CPL":[330,411],"difficult":[333],"undertake:":[335],"they":[336,626],"require":[337],"high-energy":[338],"photons,":[341],"hence":[342],"use":[344],"synchrotron.":[347],"used":[352,591],"quantum":[353],"mechanical":[354],"calculations":[355],"obtain":[357],"electronic":[359],"circular":[360],"dichro\u00efsm":[361],"(ECD)":[362],"spectra":[363],"two":[365],"-methylated":[366],"-amino-acids,":[367],"alpha-amino-acid.":[374],"Differences":[375],"observed":[377,486],"between":[378,801],"spectra,":[380],"propose":[383],"scenario":[385,426,451,532,553,637,664,790],"experimental":[389],"measurements":[390],"reported":[391],"here":[392],"above:":[393],"enantioselective":[395],"photolysis,":[396],"gas":[399,489],"phase":[400,490],"low":[402,634],"temperatures":[403],"(20K":[404],"most),":[406],"with":[412,714],"lambda>210":[413],"nm.":[414],"Under":[415,752],"would":[423,554],"occur.":[424],"concerns":[427],"Earth:":[437],"some":[446],"second":[450],"that":[452,614,705,730,741,759,814,840,862],"Earth,":[467,550],"role":[471,758,839,861],"alpha-amino-acid":[474],"serine":[475,570,582,617,655],"has":[476,499,527,533],"suggested":[478,638],"Serine":[482],"clusters":[483,496,618],"mass":[492],"spectrometry.":[493],"Among":[494],"octamer":[498,526],"shown":[501],"magic":[505],"number":[506],"cluster":[507],"preference":[512,568],"homochirality.":[514],"An":[515],"via":[518,793],"cycles":[519],"formation":[521,687],"dissociation":[523],"suggested.":[529],"complete":[531],"however":[534],"literature":[539,641,652],"but":[551,856],"any":[552],"most":[555,615,835],"probably":[556,616,836],"include":[557],"aqueous":[559],"phase.":[560],"We":[561,609,805],"aimed":[562],"determining":[564],"homochiral":[567,742],"octamers":[571,583],"exists":[573],"solution":[575],"therefore":[577],"exist":[584],"solution.":[586,608],"For":[587],"study,":[589],"nuclear":[592,794],"magnetic":[593,795],"resonance":[594,796],"infrared":[596],"spectroscopies,":[597],"well-adapted":[600],"study":[603],"molecular":[605],"assemblies":[606],"were":[610,744,806],"demonstrate":[613],"solution,":[623],"it":[628,727,821],"extremely":[633],"concentration.":[635],"discussed":[643],"results":[649,834],"data":[653],"clusters.":[656],"last":[658,780],"hypothesis,":[659,754],"possible":[663],"known":[677],"prebiotic":[678],"synthesis":[679],"pathways":[680],"carbohydrates,":[691],"minor":[697],"product":[698],"syntheses.":[701],"Our":[702,789,833],"hypothesis":[703],"selected":[710],"through":[711],"favorable":[712],"interactions":[713],"already":[716],"form.":[725],"Indeed,":[726],"plausible":[729],"peptidic":[732],"world":[733],"emerged":[734],"when":[748,817],"was":[750,791],"synthesized.":[751],"alpha-l-amino-acids":[760],"played":[763,845,866],"alpha-d-ribofuranose":[768],"work":[775],"homochirality:":[786],"transfer.":[788],"studies":[797],"interaction":[800,819],"carbohydrates.":[804],"show":[809],"that,":[810],"systems":[813],"studied,":[816],"occurs":[820],"weak":[824],"(affinity":[825],"constant":[826],"less":[827],"than":[828],"1M\u22121)":[829],"non":[831],"enantioselective.":[832],"discard":[837,859],"alone":[842],"nucleotides,":[855],"does":[857],"peptides":[863],"selection.":[869]},"counts_by_year":[],"updated_date":"2026-08-08T01:25:22.217667","created_date":"2025-10-24T00:00:00"}