{"id":"https://openalex.org/W7091715344","doi":"https://doi.org/10.4103/ijo.ijo_84_25","title":"Bilateral orbital Castleman disease: Building castles around the eye","display_name":"Bilateral orbital Castleman disease: Building castles around the eye","publication_year":2025,"publication_date":"2025-10-01","ids":{"openalex":"https://openalex.org/W7091715344","doi":"https://doi.org/10.4103/ijo.ijo_84_25"},"language":"en","primary_location":{"id":"doi:10.4103/ijo.ijo_84_25","doi":"https://doi.org/10.4103/ijo.ijo_84_25","is_oa":true,"landing_page_url":"https://doi.org/10.4103/ijo.ijo_84_25","pdf_url":null,"source":{"id":"https://openalex.org/S4210197377","display_name":"Indian Journal of Ophthalmology - Case Reports","issn_l":"2772-3070","issn":["2772-3070","2772-3089"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj"],"host_organization":"https://openalex.org/P4310320448","host_organization_name":"Medknow","host_organization_lineage":["https://openalex.org/P4310320448","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Medknow","Wolters Kluwer"],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Indian Journal of Ophthalmology - Case Reports","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://doi.org/10.4103/ijo.ijo_84_25","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5045537392","display_name":"Anna Kurian Mullasseril","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210126009","display_name":"Little Flower Hospital & Research Centre","ror":"https://ror.org/0375jhj23","country_code":"IN","type":"healthcare","lineage":["https://openalex.org/I4210126009"]}],"countries":["IN"],"is_corresponding":true,"raw_author_name":"Anna Kurian Mullasseril","raw_affiliation_strings":["Orbit and Oculoplasty Fellow, Little Flower Hospital and Research Institute, Angamaly, Kerala, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Orbit and Oculoplasty Fellow, Little Flower Hospital and Research Institute, Angamaly, Kerala, India","institution_ids":["https://openalex.org/I4210126009"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068859472","display_name":"Ani Sreedhar","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210126009","display_name":"Little Flower Hospital & Research Centre","ror":"https://ror.org/0375jhj23","country_code":"IN","type":"healthcare","lineage":["https://openalex.org/I4210126009"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Ani Sreedhar","raw_affiliation_strings":["Orbit and Oculoplasty, Ophthalmology Department, Little Flower Hospital and Research Institute, Angamaly, Kerala, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Orbit and Oculoplasty, Ophthalmology Department, Little Flower Hospital and Research Institute, Angamaly, Kerala, India","institution_ids":["https://openalex.org/I4210126009"]}]},{"author_position":"middle","author":{"id":null,"display_name":"JK Ann","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210126009","display_name":"Little Flower Hospital & Research Centre","ror":"https://ror.org/0375jhj23","country_code":"IN","type":"healthcare","lineage":["https://openalex.org/I4210126009"]}],"countries":["IN"],"is_corresponding":true,"raw_author_name":"JK Ann","raw_affiliation_strings":["Orbit and Oculoplasty, Ophthalmology Department, Little Flower Hospital and Research Institute, Angamaly, Kerala, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Orbit and Oculoplasty, Ophthalmology Department, Little Flower Hospital and Research Institute, Angamaly, Kerala, India","institution_ids":["https://openalex.org/I4210126009"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Dona Ann Mathew","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210126009","display_name":"Little Flower Hospital & Research Centre","ror":"https://ror.org/0375jhj23","country_code":"IN","type":"healthcare","lineage":["https://openalex.org/I4210126009"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Dona Ann Mathew","raw_affiliation_strings":["Orbit and Oculoplasty, Ophthalmology Department, Little Flower Hospital and Research Institute, Angamaly, Kerala, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Orbit and Oculoplasty, Ophthalmology Department, Little Flower Hospital and Research Institute, Angamaly, Kerala, India","institution_ids":["https://openalex.org/I4210126009"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Sajitha Abdusamad","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210126009","display_name":"Little Flower Hospital & Research Centre","ror":"https://ror.org/0375jhj23","country_code":"IN","type":"healthcare","lineage":["https://openalex.org/I4210126009"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Sajitha Abdusamad","raw_affiliation_strings":["Pathology, Little Flower Hospital and Research Institute, Angamaly, Kerala, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pathology, Little Flower Hospital and Research Institute, Angamaly, Kerala, India","institution_ids":["https://openalex.org/I4210126009"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5111878489","display_name":"Jophy Varghese","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jophy Varghese","raw_affiliation_strings":["Consultant Pathologist, DDRC Agilus Diagnostics, Ernakulam, Kerala, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Consultant Pathologist, DDRC Agilus Diagnostics, Ernakulam, Kerala, India","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5045537392"],"corresponding_institution_ids":["https://openalex.org/I4210126009"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.53571405,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"5","issue":"4","first_page":"611","last_page":"615"},"is_retracted":false,"is_paratext":false,"is_xpac":true,"primary_topic":{"id":"https://openalex.org/T13314","display_name":"Lymphadenopathy Diagnosis and Analysis","score":0.9063000082969666,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T13314","display_name":"Lymphadenopathy Diagnosis and Analysis","score":0.9063000082969666,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10685","display_name":"Viral-associated cancers and disorders","score":0.08250000327825546,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10185","display_name":"Lymphoma Diagnosis and Treatment","score":0.00419999985024333,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/castleman-disease","display_name":"Castleman disease","score":0.8870000243186951},{"id":"https://openalex.org/keywords/bilateral-orbital-involvement","display_name":"bilateral orbital involvement","score":0.8420000076293945},{"id":"https://openalex.org/keywords/lymphoproliferative-disorders","display_name":"lymphoproliferative disorders","score":0.8550000190734863},{"id":"https://openalex.org/keywords/differential-diagnosis-from-lymphoma","display_name":"differential diagnosis from lymphoma","score":0.7929999828338623},{"id":"https://openalex.org/keywords/histopathology","display_name":"histopathology","score":0.7350000143051147}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8025000095367432},{"id":"https://openalex.org/C196644772","wikidata":"https://www.wikidata.org/wiki/Q3884964","display_name":"Orbit (dynamics)","level":2,"score":0.6840999722480774},{"id":"https://openalex.org/C2776054410","wikidata":"https://www.wikidata.org/wiki/Q1947302","display_name":"Castleman disease","level":3,"score":0.5145999789237976},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.47440001368522644},{"id":"https://openalex.org/C2779338263","wikidata":"https://www.wikidata.org/wiki/Q208414","display_name":"Lymphoma","level":2,"score":0.45750001072883606},{"id":"https://openalex.org/C2779701055","wikidata":"https://www.wikidata.org/wiki/Q929833","display_name":"Rare disease","level":3,"score":0.41100001335144043},{"id":"https://openalex.org/C2780581723","wikidata":"https://www.wikidata.org/wiki/Q775940","display_name":"Diplopia","level":2,"score":0.3790999948978424},{"id":"https://openalex.org/C16005928","wikidata":"https://www.wikidata.org/wiki/Q171171","display_name":"Dermatology","level":1,"score":0.3587000072002411},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.3580999970436096},{"id":"https://openalex.org/C2909668393","wikidata":"https://www.wikidata.org/wiki/Q156075","display_name":"Orbital Diseases","level":4,"score":0.3465000092983246},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.32409998774528503},{"id":"https://openalex.org/C57742111","wikidata":"https://www.wikidata.org/wiki/Q7168","display_name":"Histology","level":2,"score":0.3003000020980835},{"id":"https://openalex.org/C2779231881","wikidata":"https://www.wikidata.org/wiki/Q5977147","display_name":"Medical literature","level":2,"score":0.2946000099182129},{"id":"https://openalex.org/C2777073666","wikidata":"https://www.wikidata.org/wiki/Q1592207","display_name":"Pseudolymphoma","level":3,"score":0.2800999879837036},{"id":"https://openalex.org/C2776148792","wikidata":"https://www.wikidata.org/wiki/Q3041498","display_name":"Eye disease","level":2,"score":0.27390000224113464},{"id":"https://openalex.org/C146357865","wikidata":"https://www.wikidata.org/wiki/Q1123245","display_name":"Stage (stratigraphy)","level":2,"score":0.2736000120639801}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.4103/ijo.ijo_84_25","doi":"https://doi.org/10.4103/ijo.ijo_84_25","is_oa":true,"landing_page_url":"https://doi.org/10.4103/ijo.ijo_84_25","pdf_url":null,"source":{"id":"https://openalex.org/S4210197377","display_name":"Indian Journal of Ophthalmology - Case Reports","issn_l":"2772-3070","issn":["2772-3070","2772-3089"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj"],"host_organization":"https://openalex.org/P4310320448","host_organization_name":"Medknow","host_organization_lineage":["https://openalex.org/P4310320448","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Medknow","Wolters Kluwer"],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Indian Journal of Ophthalmology - Case Reports","raw_type":"journal-article"},{"id":"pmh:oai:doaj.org/article:7a1aad143b4944dfbe00daa6c52fc4e6","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/7a1aad143b4944dfbe00daa6c52fc4e6","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Indian Journal of Ophthalmology. Case Reports, Vol 5, Iss 4, Pp 611-615 (2025)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.4103/ijo.ijo_84_25","doi":"https://doi.org/10.4103/ijo.ijo_84_25","is_oa":true,"landing_page_url":"https://doi.org/10.4103/ijo.ijo_84_25","pdf_url":null,"source":{"id":"https://openalex.org/S4210197377","display_name":"Indian Journal of Ophthalmology - Case Reports","issn_l":"2772-3070","issn":["2772-3070","2772-3089"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj"],"host_organization":"https://openalex.org/P4310320448","host_organization_name":"Medknow","host_organization_lineage":["https://openalex.org/P4310320448","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Medknow","Wolters Kluwer"],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Indian Journal of Ophthalmology - Case Reports","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9476000070571899}],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":17,"referenced_works":["https://openalex.org/W1811265259","https://openalex.org/W1967053056","https://openalex.org/W1989512873","https://openalex.org/W1997983865","https://openalex.org/W2010877578","https://openalex.org/W2024170931","https://openalex.org/W2029814506","https://openalex.org/W2037597157","https://openalex.org/W2051605066","https://openalex.org/W2067407728","https://openalex.org/W2572250031","https://openalex.org/W2955566036","https://openalex.org/W3006713791","https://openalex.org/W3211388776","https://openalex.org/W4385350527","https://openalex.org/W4386346791","https://openalex.org/W4403969486"],"related_works":[],"abstract_inverted_index":{"Castleman":[0,12,65,81],"disease":[1,13,82],"is":[2,14],"a":[3,33,49,94],"rare,":[4],"benign,":[5],"clinicopathological":[6],"entity":[7],"associated":[8],"with":[9,19,38],"lymphoproliferation.":[10],"Orbital":[11],"an":[15],"even":[16],"rarer":[17],"condition,":[18],"multicentric":[20],"involvement":[21],"of":[22,32,54,74,80,96,107],"the":[23,30,41,72,77,97,101],"orbit":[24],"being":[25],"exceptionally":[26],"uncommon.":[27],"We":[28],"report":[29],"case":[31],"61-year-old":[34],"male":[35],"who":[36],"presented":[37],"swelling":[39],"in":[40,76],"right":[42],"infraorbital":[43],"region.":[44],"However,":[45],"upon":[46],"detailed":[47],"evaluation,":[48],"bilateral":[50],"mass":[51],"clinically":[52],"suggestive":[53],"lymphoma":[55],"was":[56,61],"diagnosed,":[57],"which,":[58],"on":[59],"biopsy,":[60],"revealed":[62],"to":[63],"be":[64],"disease.":[66],"In":[67],"this":[68,108],"report,":[69],"we":[70,89],"highlight":[71],"importance":[73],"histology":[75],"definitive":[78],"diagnosis":[79],"and":[83,105,110],"its":[84],"distinctiveness":[85],"from":[86],"lymphoma.":[87],"Additionally,":[88],"provide":[90],"new":[91],"insights":[92],"(through":[93],"review":[95],"medical":[98],"literature)":[99],"into":[100],"clinical":[102],"features,":[103],"diagnosis,":[104],"treatment":[106],"rare":[109],"relatively":[111],"benign":[112],"disorder.":[113]},"counts_by_year":[],"updated_date":"2026-10-12T09:40:04.860316","created_date":"2025-10-16T00:00:00"}