{"id":"https://openalex.org/W70889396","doi":null,"title":"Impact of early vs. late tracheostomy on weaning: a retrospective analysis.","display_name":"Impact of early vs. late tracheostomy on weaning: a retrospective analysis.","publication_year":2011,"publication_date":"2011-12-01","ids":{"openalex":"https://openalex.org/W70889396","mag":"70889396","pmid":"https://pubmed.ncbi.nlm.nih.gov/21617598"},"language":"en","primary_location":{"id":"pmid:21617598","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21617598","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Minerva anestesiologica","raw_type":"Journal Article"},"volume":null,"type":"article","indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5029680202","display_name":"Johannes Bickenbach","orcid":"https://orcid.org/0000-0002-0039-8448","observed_orcids":["https://orcid.org/0000-0002-0039-8448"]},"institutions":[{"id":"https://openalex.org/I4210120689","display_name":"Universit\u00e4tsklinikum Aachen","ror":"https://ror.org/02gm5zw39","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210120689"]},{"id":"https://openalex.org/I887968799","display_name":"RWTH Aachen University","ror":"https://ror.org/04xfq0f34","country_code":"DE","type":"education","lineage":["https://openalex.org/I887968799"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"J Bickenbach","raw_affiliation_strings":["Department of Intensive Care, University Hospital Aachen, RWTH Aachen University, Aachen, Germany. jbickenbach@ukaachen.de"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Intensive Care, University Hospital Aachen, RWTH Aachen University, Aachen, Germany. jbickenbach@ukaachen.de","institution_ids":["https://openalex.org/I4210120689","https://openalex.org/I887968799"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001151898","display_name":"Michael Fries","orcid":"https://orcid.org/0000-0002-3958-8775","observed_orcids":["https://orcid.org/0000-0002-3958-8775"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M Fries","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049482984","display_name":"Vincent Offermanns","orcid":"https://orcid.org/0000-0002-2588-9390","observed_orcids":["https://orcid.org/0000-0002-2588-9390"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"V Offermanns","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036099737","display_name":"R. von Stillfried","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"R Von Stillfried","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021767295","display_name":"Rolf Rossaint","orcid":"https://orcid.org/0000-0001-7587-1693","observed_orcids":["https://orcid.org/0000-0001-7587-1693"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"R Rossaint","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"G Marx","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"G Marx","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5111534549","display_name":"R. Dembinski","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"R Dembinski","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.9043,"has_fulltext":false,"cited_by_count":37,"citation_normalized_percentile":{"value":0.85501283,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"77","issue":"12","first_page":"1176","last_page":"83"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11260","display_name":"Tracheal and airway disorders","score":0.9146000146865845,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11260","display_name":"Tracheal and airway disorders","score":0.9146000146865845,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10322","display_name":"Respiratory Support and Mechanisms","score":0.04650000110268593,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10830","display_name":"Airway Management and Intubation Techniques","score":0.026200000196695328,"subfield":{"id":"https://openalex.org/subfields/2703","display_name":"Anesthesiology and Pain Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/tracheostomy-timing","display_name":"tracheostomy timing","score":0.9039999842643738},{"id":"https://openalex.org/keywords/early-tracheostomy","display_name":"early tracheostomy","score":0.9940000176429749},{"id":"https://openalex.org/keywords/weaning-from-mechanical-ventilation","display_name":"weaning from mechanical ventilation","score":0.8659999966621399},{"id":"https://openalex.org/keywords/weaning-failure","display_name":"weaning failure","score":0.6690000295639038},{"id":"https://openalex.org/keywords/extubation-failure","display_name":"extubation failure","score":0.890999972820282},{"id":"https://openalex.org/keywords/icu-mortality","display_name":"ICU mortality","score":0.7960000038146973},{"id":"https://openalex.org/keywords/ventilator-associated-pneumonia","display_name":"ventilator-associated pneumonia","score":0.9909999966621399},{"id":"https://openalex.org/keywords/sepsis","display_name":"sepsis","score":0.9750000238418579},{"id":"https://openalex.org/keywords/duration-of-mechanical-ventilation","display_name":"mechanical ventilation duration","score":0.7929999828338623},{"id":"https://openalex.org/keywords/icu-length-of-stay","display_name":"ICU length of stay","score":0.9120000004768372},{"id":"https://openalex.org/keywords/critically-ill-patients","display_name":"critically ill patients","score":0.972000002861023}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9604614973068237},{"id":"https://openalex.org/C2780655333","wikidata":"https://www.wikidata.org/wiki/Q333203","display_name":"Weaning","level":2,"score":0.8501533269882202},{"id":"https://openalex.org/C2777080012","wikidata":"https://www.wikidata.org/wiki/Q3766250","display_name":"Mechanical ventilation","level":2,"score":0.7151486277580261},{"id":"https://openalex.org/C2776376669","wikidata":"https://www.wikidata.org/wiki/Q5094647","display_name":"Intensive care unit","level":2,"score":0.5979117155075073},{"id":"https://openalex.org/C167135981","wikidata":"https://www.wikidata.org/wiki/Q2146302","display_name":"Retrospective cohort study","level":2,"score":0.5762439370155334},{"id":"https://openalex.org/C2778716859","wikidata":"https://www.wikidata.org/wiki/Q939018","display_name":"Intubation","level":2,"score":0.5628122687339783},{"id":"https://openalex.org/C2778384902","wikidata":"https://www.wikidata.org/wiki/Q183134","display_name":"Sepsis","level":2,"score":0.5590563416481018},{"id":"https://openalex.org/C127808970","wikidata":"https://www.wikidata.org/wiki/Q385989","display_name":"Bonferroni correction","level":2,"score":0.4973752796649933},{"id":"https://openalex.org/C61511704","wikidata":"https://www.wikidata.org/wiki/Q1671857","display_name":"Incidence (geometry)","level":2,"score":0.48935455083847046},{"id":"https://openalex.org/C2991859549","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Critically ill","level":2,"score":0.4793761074542999},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.45932623744010925},{"id":"https://openalex.org/C67761136","wikidata":"https://www.wikidata.org/wiki/Q2105849","display_name":"Post-hoc analysis","level":2,"score":0.4266813099384308},{"id":"https://openalex.org/C200457457","wikidata":"https://www.wikidata.org/wiki/Q584049","display_name":"Ventilation (architecture)","level":2,"score":0.41058939695358276},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.2832562327384949},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.21890392899513245},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.14042282104492188},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.0},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C78519656","wikidata":"https://www.wikidata.org/wiki/Q101333","display_name":"Mechanical engineering","level":1,"score":0.0},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.0},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007902","descriptor_name":"Length of Stay","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014139","descriptor_name":"Tracheostomy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015300","descriptor_name":"Ventilator Weaning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015331","descriptor_name":"Cohort Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015992","descriptor_name":"Body Mass Index","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016638","descriptor_name":"Critical Illness","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017052","descriptor_name":"Hospital Mortality","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D023381","descriptor_name":"Endpoint Determination","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D053717","descriptor_name":"Pneumonia, Ventilator-Associated","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false}],"locations_count":3,"locations":[{"id":"pmid:21617598","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21617598","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Minerva anestesiologica","raw_type":"Journal Article"},{"id":"pmh:oai:publications.rwth-aachen.de:182866","doi":null,"is_oa":false,"landing_page_url":"https://publications.rwth-aachen.de/record/182866","pdf_url":null,"source":{"id":"https://openalex.org/S4306401362","display_name":"RWTH Publications (RWTH Aachen)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I887968799","host_organization_name":"RWTH Aachen University","host_organization_lineage":["https://openalex.org/I887968799"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Minerva anestesiologica 77(12), 1176-1183 (2011).","raw_type":"info:eu-repo/semantics/article"},{"id":"mag:70889396","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21617598","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[{"display_name":"Good health and well-being","score":0.8700000047683716,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W587661581","https://openalex.org/W2970160859","https://openalex.org/W3157106405","https://openalex.org/W2940730534","https://openalex.org/W7124748246","https://openalex.org/W7220669222","https://openalex.org/W4280648069","https://openalex.org/W3031510930","https://openalex.org/W4392949054","https://openalex.org/W2887881413"],"abstract_inverted_index":{"BACKGROUND:":[0],"Early":[1,92],"tracheostomy":[2,39,51,57,81,93,101,104,110,222,235],"has":[3],"been":[4],"advocated":[5],"for":[6,75,139,202],"a":[7,178,186,193],"number":[8],"of":[9,38,49,182,189,197,207,219,242],"reasons.":[10],"Especially":[11],"in":[12,60,153,236],"association":[13],"with":[14,53,160,168],"weaning":[15,87,208,220],"from":[16,33,67],"mechanical":[17,243],"ventilation,":[18],"it":[19],"is":[20,40,45,223],"known":[21],"that":[22],"an":[23],"early":[24,50,234],"timepoint":[25],"can":[26],"help":[27],"patients":[28,79],"being":[29,158,166],"weaned":[30],"more":[31],"rapidly":[32],"the":[34,127,154,161,169,203,214,227,240],"ventilator.":[35],"However,":[36],"timing":[37],"still":[41],"unknown":[42],"and":[43,55,108,184,192,245],"evidence":[44],"lacking.":[46],"The":[47,217],"effects":[48],"compared":[52,159,167],"intermediate":[54,100],"late":[56,109],"were":[58,73,89,130],"assessed":[59],"critically":[61],"ill":[62],"patients.":[63],"METHODS:":[64],"Data":[65],"collected":[66],"January":[68],"2005":[69],"to":[70,83,232,238],"December":[71],"2007":[72],"conducted":[74],"retrospective":[76],"analysis.":[77],"All":[78],"needing":[80],"due":[82],"extubation":[84],"failure":[85,88],"and/or":[86],"included":[90],"(N.=296).":[91],"(ET)":[94],"was":[95,112,150,209],"defined":[96,113],"as":[97,103,114],"\u22644":[98],"days,":[99,107],"(IT)":[102],"within":[105],"5-9":[106],"(LT)":[111],"\u226510":[115],"days":[116,191],"after":[117,221],"endotracheal":[118],"intubation.":[119],"After":[120],"proving":[121],"normal":[122],"distribution,":[123],"significant":[124],"changes":[125],"between":[126,213],"three":[128],"groups":[129],"tested":[131],"by":[132,135,226],"ANOVA":[133],"followed":[134],"post":[136],"hoc":[137],"tests":[138],"multiple":[140],"comparisons":[141],"(Bonferroni's":[142],"test).":[143],"RESULTS:":[144],"Intensive":[145],"care":[146],"unit":[147],"(ICU)":[148],"mortality":[149],"significantly":[151,179,211],"higher":[152],"LT":[155],"group":[156,171],"when":[157,165],"ET":[162,204],"but":[163],"not":[164,210,224],"IT":[170],"(40.7%":[172],"vs.":[173,175],"24.8%":[174],"17.1%).":[176],"Further,":[177],"reduced":[180],"incidence":[181],"VAP":[183],"sepsis,":[185],"smaller":[187],"amount":[188],"ventilator":[190],"shorter":[194],"ICU":[195],"length":[196,218],"stay":[198],"could":[199],"be":[200],"observed":[201],"group.":[205],"Length":[206],"different":[212],"groups.":[215],"CONCLUSION:":[216],"affected":[225],"timing.":[228],"It":[229],"seems":[230],"beneficial":[231],"favour":[233],"order":[237],"reduce":[239],"time":[241],"ventilation":[244],"its":[246],"associated":[247],"risks.":[248]},"counts_by_year":[{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":4},{"year":2020,"cited_by_count":6},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":2},{"year":2015,"cited_by_count":4},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}