{"id":"https://openalex.org/W70863301","doi":null,"title":"[A new approach to the treatment of delirium: atypical antipsychotics].","display_name":"[A new approach to the treatment of delirium: atypical antipsychotics].","publication_year":2005,"publication_date":"2005-01-01","ids":{"openalex":"https://openalex.org/W70863301","mag":"70863301","pmid":"https://pubmed.ncbi.nlm.nih.gov/16180154"},"language":"tr","primary_location":{"id":"pmid:16180154","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16180154","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Turk psikiyatri dergisi = Turkish journal of psychiatry","raw_type":"English Abstract"},"volume":null,"type":"article","indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5107858470","display_name":"Elif Onur","orcid":"https://orcid.org/0000-0002-1690-3170","observed_orcids":["https://orcid.org/0000-0002-1690-3170"]},"institutions":[{"id":"https://openalex.org/I193615760","display_name":"Dokuz Eyl\u00fcl University","ror":"https://ror.org/00dbd8b73","country_code":"TR","type":"education","lineage":["https://openalex.org/I193615760"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Elif Onur","raw_affiliation_strings":["Dokuz Eyl\u00fcl U Tip Fak., Psikiyatri AD., Izmir"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dokuz Eyl\u00fcl U Tip Fak., Psikiyatri AD., Izmir","institution_ids":["https://openalex.org/I193615760"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5007826148","display_name":"Can Cimilli","orcid":"https://orcid.org/0000-0002-3024-0027","observed_orcids":["https://orcid.org/0000-0002-3024-0027"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Can Cimilli","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":5,"citation_normalized_percentile":{"value":0.01340283,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"16","issue":"3","first_page":"216","last_page":"24"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10867","display_name":"Intensive Care Unit Cognitive Disorders","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2706","display_name":"Critical Care and Intensive Care Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10867","display_name":"Intensive Care Unit Cognitive Disorders","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2706","display_name":"Critical Care and Intensive Care Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12494","display_name":"Alcoholism and Thiamine Deficiency","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10023","display_name":"Schizophrenia research and treatment","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/delirium","display_name":"delirium","score":0.9990000128746033},{"id":"https://openalex.org/keywords/atypical-antipsychotics","display_name":"atypical antipsychotics","score":1.0},{"id":"https://openalex.org/keywords/risperidone","display_name":"risperidone","score":0.9480000138282776},{"id":"https://openalex.org/keywords/olanzapine","display_name":"olanzapine","score":1.0},{"id":"https://openalex.org/keywords/quetiapine","display_name":"quetiapine","score":0.9990000128746033},{"id":"https://openalex.org/keywords/ziprasidone","display_name":"ziprasidone","score":0.9990000128746033},{"id":"https://openalex.org/keywords/qt-interval-prolongation","display_name":"QT prolongation","score":0.8579999804496765},{"id":"https://openalex.org/keywords/typical-antipsychotics","display_name":"typical antipsychotics","score":0.8289999961853027},{"id":"https://openalex.org/keywords/benzodiazepines","display_name":"benzodiazepines","score":0.9959999918937683},{"id":"https://openalex.org/keywords/anticholinergic-effects","display_name":"anticholinergic effects","score":0.7839999794960022},{"id":"https://openalex.org/keywords/extrapyramidal-symptoms","display_name":"extrapyramidal symptoms","score":0.9089999794960022}],"concepts":[{"id":"https://openalex.org/C2779753318","wikidata":"https://www.wikidata.org/wiki/Q160796","display_name":"Delirium","level":2,"score":0.8587489128112793},{"id":"https://openalex.org/C2780634440","wikidata":"https://www.wikidata.org/wiki/Q408535","display_name":"Quetiapine","level":3,"score":0.7391170859336853},{"id":"https://openalex.org/C2776619155","wikidata":"https://www.wikidata.org/wiki/Q201872","display_name":"Olanzapine","level":3,"score":0.731598973274231},{"id":"https://openalex.org/C2780057945","wikidata":"https://www.wikidata.org/wiki/Q412443","display_name":"Risperidone","level":3,"score":0.5929025411605835},{"id":"https://openalex.org/C2777270317","wikidata":"https://www.wikidata.org/wiki/Q205517","display_name":"Ziprasidone","level":4,"score":0.5907803177833557},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5625240802764893},{"id":"https://openalex.org/C2780616385","wikidata":"https://www.wikidata.org/wiki/Q1385411","display_name":"Extrapyramidal symptoms","level":4,"score":0.5504679083824158},{"id":"https://openalex.org/C2778689640","wikidata":"https://www.wikidata.org/wiki/Q113259","display_name":"Anticholinergic","level":2,"score":0.5190628170967102},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.4987468719482422},{"id":"https://openalex.org/C2777393122","wikidata":"https://www.wikidata.org/wiki/Q416417","display_name":"Akathisia","level":4,"score":0.43370482325553894},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.3768481910228729},{"id":"https://openalex.org/C2780494398","wikidata":"https://www.wikidata.org/wiki/Q208144","display_name":"Antipsychotic","level":3,"score":0.32235243916511536},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.2738529443740845},{"id":"https://openalex.org/C2776412080","wikidata":"https://www.wikidata.org/wiki/Q7431605","display_name":"Schizophrenia (object-oriented programming)","level":2,"score":0.2381226122379303}],"mesh":[{"descriptor_ui":"D003693","descriptor_name":"Delirium","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014150","descriptor_name":"Antipsychotic Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true}],"locations_count":1,"locations":[{"id":"pmid:16180154","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16180154","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Turk psikiyatri dergisi = Turkish journal of psychiatry","raw_type":"English Abstract"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2143832835","https://openalex.org/W7097862640","https://openalex.org/W1835525282","https://openalex.org/W2153516004","https://openalex.org/W2574333839","https://openalex.org/W2047325996","https://openalex.org/W2080863392","https://openalex.org/W1948565301","https://openalex.org/W6928873854","https://openalex.org/W1951236991"],"abstract_inverted_index":{"Delirium":[0,35],"is":[1,36,56],"a":[2,8,40,137],"common":[3],"neuropsychiatric":[4],"syndrome":[5],"that":[6,175,208],"involves":[7,66],"number":[9,138],"of":[10,30,61,64,84,92,99,131,139,156,163,166,180,194,219,230,236,242],"symptoms":[11,63],"including":[12],"diffuse":[13],"cognitive":[14,102],"impairment,":[15],"delusions,":[16],"hallucinations,":[17],"mood":[18],"lability":[19],"and":[20,44,48,50,58,68,75,88,95,114,154,178,182,189,192,201,204],"disturbances":[21],"in":[22,28,80,107,128,186,198,221,227,239],"the":[23,62,81,96,129,161,164,176,190,209,213,217,228,231,234,240],"sleep-wake":[24],"cycle.":[25],"It":[26],"occurs":[27],"10-30%":[29],"hospitalized":[31],"medically":[32],"ill":[33],"patients.":[34],"also":[37],"associated":[38],"with":[39,168],"prolonged":[41],"hospital":[42],"stay":[43],"increased":[45],"functional":[46],"decline":[47],"morbidity":[49],"mortality":[51],"rates,":[52],"particularly":[53],"if":[54],"it":[55,171,205],"unrecognized":[57],"untreated.":[59],"Management":[60],"delirium":[65,108,167,222],"non-pharmacological":[67],"pharmacological":[69,82],"interventions.":[70],"Until":[71],"recently,":[72],"typical":[73,93],"antipsychotics":[74,94,121,238],"benzodiazepines":[76,100],"were":[77,184,196,225],"commonly":[78],"used":[79],"treatment":[83,130,165,241],"delirium.":[85,243],"The":[86],"extrapyramidal":[87],"anticholinergic":[89],"side":[90,210],"effects":[91,98],"negative":[97],"on":[101,233],"functions":[103],"limit":[104],"their":[105,142],"use":[106,218,235],"patients,":[109],"who":[110,115],"are":[111,136],"generally":[112],"old":[113],"have":[116,122,146],"other":[117],"medical":[118],"problems.":[119],"Atypical":[120],"been":[123,173],"shown":[124,185,197,207],"to":[125],"be":[126],"effective":[127],"psychotic":[132],"symptoms.":[133],"Although":[134],"there":[135],"studies":[140,145,162],"showing":[141],"efficacy,":[143],"most":[144],"some":[147],"limitations":[148],"such":[149],"as":[150],"small":[151],"sample":[152],"size":[153],"absence":[155],"control":[157],"groups.":[158],"Upon":[159],"reviewing":[160],"atypical":[169,237],"antipsychotics,":[170],"has":[172],"observed":[174],"efficacy":[177,191],"safety":[179,193],"risperidone":[181],"olanzapine":[183],"randomized":[187],"trials,":[188],"quetiapine":[195],"case":[199],"reports":[200],"retrospective":[202],"studies,":[203],"was":[206],"effect":[211],"over":[212],"QT":[214],"interval":[215],"limits":[216],"ziprasidone":[220],"treatment.":[223],"Suggestions":[224],"made":[226],"light":[229],"literature":[232]},"counts_by_year":[{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}