{"id":"https://openalex.org/W70672240","doi":"https://doi.org/10.1007/978-1-4419-1160-5_2","title":"Mouse Xenograft Models for Drug Discovery in Pancreatic Cancer","display_name":"Mouse Xenograft Models for Drug Discovery in Pancreatic Cancer","publication_year":2010,"publication_date":"2010-01-01","ids":{"openalex":"https://openalex.org/W70672240","doi":"https://doi.org/10.1007/978-1-4419-1160-5_2","mag":"70672240"},"language":"en","primary_location":{"id":"doi:10.1007/978-1-4419-1160-5_2","doi":"https://doi.org/10.1007/978-1-4419-1160-5_2","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-1-4419-1160-5_2","pdf_url":null,"source":{"id":"https://openalex.org/S4306463937","display_name":"Springer eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Drug Discovery in Pancreatic Cancer","raw_type":"book-chapter"},"volume":{"id":"https://openalex.org/W2498648578","display_name":"Drug Discovery in Pancreatic Cancer"},"type":"book-chapter","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5017739964","display_name":"Bel\u00e9n Rubio\u2010Viqueira","orcid":"https://orcid.org/0000-0001-5987-9214","observed_orcids":["https://orcid.org/0000-0001-5987-9214"]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]},{"id":"https://openalex.org/I4210164401","display_name":"Sidney Kimmel Comprehensive Cancer Center","ror":"https://ror.org/05m5b8x20","country_code":"US","type":"facility","lineage":["https://openalex.org/I2799853436","https://openalex.org/I4210164401"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Belen Rubio-Viqueira","raw_affiliation_strings":["The Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, 1650 Orleans St., Baltimore, MD, 21231-1000, USA","Hospital Madrid Norte Sanchinarro"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, 1650 Orleans St., Baltimore, MD, 21231-1000, USA","institution_ids":["https://openalex.org/I145311948","https://openalex.org/I4210164401"]},{"raw_affiliation_string":"Hospital Madrid Norte Sanchinarro","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5086660695","display_name":"Manuel M. Hidalgo","orcid":"https://orcid.org/0000-0002-3765-3318","observed_orcids":["https://orcid.org/0000-0002-3765-3318"]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]},{"id":"https://openalex.org/I4210164401","display_name":"Sidney Kimmel Comprehensive Cancer Center","ror":"https://ror.org/05m5b8x20","country_code":"US","type":"facility","lineage":["https://openalex.org/I2799853436","https://openalex.org/I4210164401"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Manuel Hidalgo","raw_affiliation_strings":["The Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, 1650 Orleans St., Baltimore, MD, 21231-1000, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, 1650 Orleans St., Baltimore, MD, 21231-1000, USA","institution_ids":["https://openalex.org/I145311948","https://openalex.org/I4210164401"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5086660695"],"corresponding_institution_ids":["https://openalex.org/I145311948","https://openalex.org/I4210164401"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.03726708,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":null,"issue":null,"first_page":"29","last_page":"49"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10231","display_name":"Pancreatic and Hepatic Oncology Research","score":0.9937000274658203,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10231","display_name":"Pancreatic and Hepatic Oncology Research","score":0.9937000274658203,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10336","display_name":"Cancer Cells and Metastasis","score":0.0015999999595806003,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10760","display_name":"Pancreatitis Pathology and Treatment","score":0.0008999999845400453,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pancreatic-cancer","display_name":"pancreatic cancer","score":0.953000009059906},{"id":"https://openalex.org/keywords/mouse-xenograft-model","display_name":"xenograft mouse model","score":0.984000027179718},{"id":"https://openalex.org/keywords/anticancer-drug-discovery","display_name":"anticancer drug discovery","score":0.8479999899864197},{"id":"https://openalex.org/keywords/preclinical-drug-screening","display_name":"preclinical drug screening","score":0.8429999947547913},{"id":"https://openalex.org/keywords/pharmacokinetics","display_name":"pharmacokinetics","score":0.6859999895095825},{"id":"https://openalex.org/keywords/pharmacodynamics","display_name":"pharmacodynamics","score":0.921999990940094}],"concepts":[{"id":"https://openalex.org/C2780210213","wikidata":"https://www.wikidata.org/wiki/Q212961","display_name":"Pancreatic cancer","level":3,"score":0.6450310349464417},{"id":"https://openalex.org/C74187038","wikidata":"https://www.wikidata.org/wiki/Q1418791","display_name":"Drug discovery","level":2,"score":0.5816607475280762},{"id":"https://openalex.org/C2780035454","wikidata":"https://www.wikidata.org/wiki/Q8386","display_name":"Drug","level":2,"score":0.5353842973709106},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4569672644138336},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.4542527496814728},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.4499005079269409},{"id":"https://openalex.org/C3020340455","wikidata":"https://www.wikidata.org/wiki/Q974135","display_name":"Cancer drugs","level":3,"score":0.41977548599243164},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.33125007152557373},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2816982865333557},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.27855798602104187},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.23166820406913757},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.16220968961715698}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1007/978-1-4419-1160-5_2","doi":"https://doi.org/10.1007/978-1-4419-1160-5_2","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-1-4419-1160-5_2","pdf_url":null,"source":{"id":"https://openalex.org/S4306463937","display_name":"Springer eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Drug Discovery in Pancreatic Cancer","raw_type":"book-chapter"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9391000270843506,"id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":87,"referenced_works":["https://openalex.org/W25117316","https://openalex.org/W36141288","https://openalex.org/W54649336","https://openalex.org/W88876866","https://openalex.org/W93205879","https://openalex.org/W132042431","https://openalex.org/W159782486","https://openalex.org/W1258890488","https://openalex.org/W1494987922","https://openalex.org/W1518709998","https://openalex.org/W1527872329","https://openalex.org/W1536420296","https://openalex.org/W1544246953","https://openalex.org/W1785779992","https://openalex.org/W1838229861","https://openalex.org/W1866472760","https://openalex.org/W1891860149","https://openalex.org/W1943657748","https://openalex.org/W1963761815","https://openalex.org/W1966687379","https://openalex.org/W1969066633","https://openalex.org/W1973460244","https://openalex.org/W1984523724","https://openalex.org/W1992252639","https://openalex.org/W1993336164","https://openalex.org/W1999433592","https://openalex.org/W2000692224","https://openalex.org/W2001679453","https://openalex.org/W2007366900","https://openalex.org/W2008714016","https://openalex.org/W2010965178","https://openalex.org/W2025167618","https://openalex.org/W2029150803","https://openalex.org/W2037554647","https://openalex.org/W2039828110","https://openalex.org/W2043696829","https://openalex.org/W2044969094","https://openalex.org/W2049545781","https://openalex.org/W2050555902","https://openalex.org/W2056687480","https://openalex.org/W2061969206","https://openalex.org/W2063038041","https://openalex.org/W2068391687","https://openalex.org/W2071057030","https://openalex.org/W2071895577","https://openalex.org/W2077484102","https://openalex.org/W2081669881","https://openalex.org/W2082140471","https://openalex.org/W2082717401","https://openalex.org/W2089837703","https://openalex.org/W2100874086","https://openalex.org/W2101977659","https://openalex.org/W2102119680","https://openalex.org/W2105830911","https://openalex.org/W2109694492","https://openalex.org/W2112329736","https://openalex.org/W2115215389","https://openalex.org/W2120191503","https://openalex.org/W2121120744","https://openalex.org/W2121175754","https://openalex.org/W2121604817","https://openalex.org/W2129056290","https://openalex.org/W2131002009","https://openalex.org/W2132919001","https://openalex.org/W2134819449","https://openalex.org/W2137905602","https://openalex.org/W2142007492","https://openalex.org/W2142152915","https://openalex.org/W2142496199","https://openalex.org/W2151957470","https://openalex.org/W2159166087","https://openalex.org/W2159698605","https://openalex.org/W2161821474","https://openalex.org/W2162151760","https://openalex.org/W2163057848","https://openalex.org/W2172077519","https://openalex.org/W2182021524","https://openalex.org/W2193705234","https://openalex.org/W2222638000","https://openalex.org/W2243979287","https://openalex.org/W2256532529","https://openalex.org/W2324684567","https://openalex.org/W2334507849","https://openalex.org/W2406855309","https://openalex.org/W2414639566","https://openalex.org/W2415616186","https://openalex.org/W3126876813"],"related_works":["https://openalex.org/W2039058362","https://openalex.org/W1891860149","https://openalex.org/W2166783527","https://openalex.org/W2172077519","https://openalex.org/W2951605527","https://openalex.org/W2245408165","https://openalex.org/W2001679453","https://openalex.org/W7160833840","https://openalex.org/W98413476","https://openalex.org/W2940157760"],"abstract_inverted_index":null,"counts_by_year":[{"year":2014,"cited_by_count":1}],"updated_date":"2026-10-14T16:39:01.820549","created_date":"2016-06-24T00:00:00"}