{"id":"https://openalex.org/W7061963580","doi":null,"title":"The Role of Internal Copies in Dexterous Forelimb Movement","display_name":"The Role of Internal Copies in Dexterous Forelimb Movement","publication_year":2023,"publication_date":"2023-01-01","ids":{"openalex":"https://openalex.org/W7061963580"},"language":"en","primary_location":{"id":"pmh:oai:escholarship.org:ark:/13030/qt3881h0cp","doi":null,"is_oa":true,"landing_page_url":"https://escholarship.org/uc/item/3881h0cp","pdf_url":"https://escholarship.org/content/qt3881h0cp/qt3881h0cp.pdf","source":{"id":"https://openalex.org/S4306400115","display_name":"eScholarship (California Digital Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2801248553","host_organization_name":"California Digital Library","host_organization_lineage":["https://openalex.org/I2801248553"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"etd"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://escholarship.org/content/qt3881h0cp/qt3881h0cp.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Sanders, Elischa Jamal","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Sanders, Elischa Jamal","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":true,"primary_topic":{"id":"https://openalex.org/T10982","display_name":"Motor Control and Adaptation","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10982","display_name":"Motor Control and Adaptation","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10448","display_name":"Memory and Neural Mechanisms","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10784","display_name":"Muscle activation and electromyography studies","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/lateral-reticular-nucleus","display_name":"lateral reticular nucleus","score":0.9660000205039978},{"id":"https://openalex.org/keywords/propriospinal-neurons","display_name":"propriospinal neurons","score":0.8730000257492065},{"id":"https://openalex.org/keywords/cerebellum","display_name":"cerebellum","score":0.8820000290870667},{"id":"https://openalex.org/keywords/online-motor-control","display_name":"online motor control","score":0.5350000262260437},{"id":"https://openalex.org/keywords/ataxia","display_name":"ataxia","score":0.7260000109672546},{"id":"https://openalex.org/keywords/single-unit-recording","display_name":"single-unit recording","score":0.5849999785423279},{"id":"https://openalex.org/keywords/cervical-spinal-cord","display_name":"cervical spinal cord","score":0.6930000185966492}],"concepts":[{"id":"https://openalex.org/C2778646069","wikidata":"https://www.wikidata.org/wiki/Q5468632","display_name":"Forelimb","level":2,"score":0.9215999841690063},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.6722000241279602},{"id":"https://openalex.org/C28427503","wikidata":"https://www.wikidata.org/wiki/Q13580300","display_name":"Internal model","level":3,"score":0.592199981212616},{"id":"https://openalex.org/C2780226923","wikidata":"https://www.wikidata.org/wiki/Q929848","display_name":"Movement (music)","level":2,"score":0.5679000020027161},{"id":"https://openalex.org/C2779652256","wikidata":"https://www.wikidata.org/wiki/Q130983","display_name":"Cerebellum","level":2,"score":0.5554999709129333},{"id":"https://openalex.org/C551621295","wikidata":"https://www.wikidata.org/wiki/Q182228","display_name":"Brainstem","level":2,"score":0.5525000095367432},{"id":"https://openalex.org/C2776956477","wikidata":"https://www.wikidata.org/wiki/Q6495688","display_name":"Lateral reticular nucleus","level":4,"score":0.49639999866485596},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4645000100135803},{"id":"https://openalex.org/C94487597","wikidata":"https://www.wikidata.org/wiki/Q11101","display_name":"Sensory system","level":2,"score":0.454800009727478},{"id":"https://openalex.org/C137813230","wikidata":"https://www.wikidata.org/wiki/Q2996165","display_name":"Motor control","level":2,"score":0.4481000006198883},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.36570000648498535},{"id":"https://openalex.org/C2778655484","wikidata":"https://www.wikidata.org/wiki/Q750588","display_name":"Reticular formation","level":3,"score":0.3513000011444092},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.35120001435279846},{"id":"https://openalex.org/C39920418","wikidata":"https://www.wikidata.org/wiki/Q11476","display_name":"Kinematics","level":2,"score":0.31060001254081726},{"id":"https://openalex.org/C2780723820","wikidata":"https://www.wikidata.org/wiki/Q1934178","display_name":"Nucleus","level":2,"score":0.30480000376701355},{"id":"https://openalex.org/C95190701","wikidata":"https://www.wikidata.org/wiki/Q3268002","display_name":"Reticular connective tissue","level":2,"score":0.30230000615119934},{"id":"https://openalex.org/C2775845787","wikidata":"https://www.wikidata.org/wiki/Q5250377","display_name":"Deep cerebellar nuclei","level":4,"score":0.27059999108314514},{"id":"https://openalex.org/C171139928","wikidata":"https://www.wikidata.org/wiki/Q2915553","display_name":"Motor system","level":2,"score":0.2635999917984009},{"id":"https://openalex.org/C2780196419","wikidata":"https://www.wikidata.org/wiki/Q1762173","display_name":"Nerve net","level":2,"score":0.25769999623298645},{"id":"https://openalex.org/C152478114","wikidata":"https://www.wikidata.org/wiki/Q660910","display_name":"Neurophysiology","level":2,"score":0.2574000060558319}],"mesh":[],"locations_count":1,"locations":[{"id":"pmh:oai:escholarship.org:ark:/13030/qt3881h0cp","doi":null,"is_oa":true,"landing_page_url":"https://escholarship.org/uc/item/3881h0cp","pdf_url":"https://escholarship.org/content/qt3881h0cp/qt3881h0cp.pdf","source":{"id":"https://openalex.org/S4306400115","display_name":"eScholarship (California Digital Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2801248553","host_organization_name":"California Digital Library","host_organization_lineage":["https://openalex.org/I2801248553"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"etd"}],"best_oa_location":{"id":"pmh:oai:escholarship.org:ark:/13030/qt3881h0cp","doi":null,"is_oa":true,"landing_page_url":"https://escholarship.org/uc/item/3881h0cp","pdf_url":"https://escholarship.org/content/qt3881h0cp/qt3881h0cp.pdf","source":{"id":"https://openalex.org/S4306400115","display_name":"eScholarship (California Digital Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2801248553","host_organization_name":"California Digital Library","host_organization_lineage":["https://openalex.org/I2801248553"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"etd"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7061963580.pdf","grobid_xml":"https://content.openalex.org/works/W7061963580.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2125043585","https://openalex.org/W2047911256","https://openalex.org/W2137731584","https://openalex.org/W2106162105","https://openalex.org/W1584822079","https://openalex.org/W4409431982","https://openalex.org/W2604660342","https://openalex.org/W7103171699","https://openalex.org/W4413933963","https://openalex.org/W2789022097"],"abstract_inverted_index":{"It":[0],"has":[1],"long":[2],"been":[3],"proposed":[4],"that":[5,50,64,137,211,239],"volitional,":[6],"dexterous":[7,220,247],"forelimb":[8,122,221,248,313,318],"movements":[9,35,249],"require":[10],"rapid":[11],"online":[12],"correction":[13],"to":[14,39,58,61,102,120,130,142,149,165,185,197,230,274,291,336],"achieve":[15],"consistent":[16],"end-point":[17],"accuracy.":[18],"Sensory":[19],"feedback":[20,74],"from":[21,86],"the":[22,59,66,69,92,103,126,131,143,150,166,169,176,181,213,225,228,240,297,321,332],"limb":[23,284],"provides":[24,204,237],"one":[25,117],"source":[26,81],"of":[27,53,68,82,89,207,216,227,299,317,324],"information":[28,112,164],"about":[29],"movement":[30,77,222],"errors.":[31],"However,":[32],"some":[33],"corrective":[34],"occur":[36],"too":[37],"quickly":[38],"be":[40,186],"explained":[41],"purely":[42],"by":[43],"sensory":[44],"feedback.":[45],"Instead,":[46],"it":[47,134],"is":[48,135,168,183,242,255],"thought":[49,136],"internal":[51,83,140,162,191,199,217,232,325],"copies":[52,84,141,192,218,326],"motor":[54,111,123,208,343],"commands":[55],"are":[56,147,260,308],"sent":[57,148],"cerebellum":[60,167],"generate":[62],"estimates":[63],"predict":[65],"state":[67],"limb,":[70],"providing":[71],"a":[72,87,153,171,187,205,279],"faster":[73],"pathway":[75],"for":[76,157,189,219,282],"correction.":[78],"A":[79],"potential":[80],"comes":[85],"subset":[88],"interneurons":[90],"in":[91,175,244,296],"cervical":[93],"spinal":[94,190],"cord,":[95],"propriospinal":[96],"neurons":[97,259,307],"(PNs),":[98],"which":[99],"send":[100,114,139],"projections":[101],"lateral":[104],"reticular":[105],"nucleus":[106,173],"(LRN).":[107],"PNs":[108,138],"receive":[109],"descending":[110],"and":[113,125,160,193,223,269,339,344],"bifurcating":[115],"projections;":[116],"branch":[118,128],"descends":[119],"innervate":[121],"neurons,":[124],"other":[127],"ascends":[129],"LRN.":[132],"Thus,":[133],"LRN":[144,182,229,241,258,298,306],"before":[145],"they":[146],"cerebellum.":[151],"Therefore,":[152],"putative":[154],"neural":[155],"candidate":[156],"receiving,":[158],"processing,":[159],"sending":[161],"copy":[163,200,233],"LRN,":[170],"brainstem":[172],"located":[174],"ventral,":[177],"caudal":[178],"medulla.":[179],"Ultimately,":[180],"hypothesized":[184,214],"hub":[188],"an":[194,289],"access":[195],"point":[196],"evaluate":[198,231],"function.":[201,234],"Chapter":[202,235,286],"1":[203],"review":[206],"control":[209,316],"principles":[210],"highlight":[212],"function":[215],"motivates":[224],"use":[226],"2":[236],"evidence":[238],"involved":[243],"executing":[245],"accurate":[246],"because":[250],"mouse":[251],"pellet":[252],"reaching":[253,277],"behavior":[254],"changed":[256],"when":[257],"ablated":[261],"or":[262],"optogenetically":[263],"silenced.":[264],"Reach":[265],"trajectories":[266],"change":[267],"(ablation)":[268],"slow":[270],"down":[271],"(optogenetic":[272],"inhibition)":[273],"maintain":[275],"their":[276],"accuracy,":[278],"classic":[280],"compensation":[281],"ataxic":[283],"movements.":[285],"3":[287],"describes":[288],"approach":[290],"recording":[292],"single":[293],"unit":[294],"activity":[295],"awake":[300],"behaving":[301],"animals.":[302],"Our":[303],"results":[304],"indicate,":[305],"heterogeneously":[309],"modulated":[310],"during":[311],"active":[312],"movement.":[314],"Beyond":[315],"movement,":[319],"determining":[320],"functional":[322],"significance":[323],"will":[327],"provide":[328],"insight":[329],"into":[330],"strategies":[331],"nervous":[333],"system":[334],"uses":[335],"continuously":[337],"monitor":[338],"rapidly":[340],"update":[341],"different":[342],"cognitive":[345],"behaviors.":[346]},"counts_by_year":[],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2025-10-10T00:00:00"}